4ABI
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![BU of 4abi by Molmil](/molmil-images/mine/4abi) | Co-complex structure of bovine trypsin with a modified Bowman-Birk inhibitor (PtA)SFTI-1(1,14), that was 1,4-disubstituted with a 1,2,3- trizol to mimic a trans amide bond | Descriptor: | CALCIUM ION, CATIONIC TRYPSIN, DIMETHYLFORMAMIDE, ... | Authors: | Schmelz, S, Empting, M, Tischler, M, Nasu, D, Heinz, D, Kolmar, H. | Deposit date: | 2011-12-08 | Release date: | 2012-03-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Braces for the Peptide Backbone: Insights Into Structure-Activity Relation-Ships of Protease Inhibitor Mimics with Locked Amide Conformations Angew.Chem.Int.Ed.Engl., 51, 2012
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4ABJ
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![BU of 4abj by Molmil](/molmil-images/mine/4abj) | Co-complex structure of bovine trypsin with a modified Bowman-Birk inhibitor (IcA)SFTI-1(1,14), that was 1,5-disubstituted with 1,2,3- trizol to mimic a cis amide bond | Descriptor: | CALCIUM ION, CATIONIC TRYPSIN, DIMETHYLFORMAMIDE, ... | Authors: | Schmelz, S, Empting, M, Tischler, M, Nasu, D, Heinz, D, Kolmar, H. | Deposit date: | 2011-12-08 | Release date: | 2012-03-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Braces for the Peptide Backbone: Insights Into Structure-Activity Relation-Ships of Protease Inhibitor Mimics with Locked Amide Conformations Angew.Chem.Int.Ed.Engl., 51, 2012
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4ABF
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![BU of 4abf by Molmil](/molmil-images/mine/4abf) | Fragments bound to bovine trypsin for the SAMPL challenge | Descriptor: | 1,2-ETHANEDIOL, 1-(5-BROMO-1-BENZOTHIOPHEN-3-YL)METHANAMINE, CALCIUM ION, ... | Authors: | Newman, J, Peat, T.S. | Deposit date: | 2011-12-08 | Release date: | 2012-02-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | The Dingo Dataset: A Comprehensive Set of Data for the Sampl Challenge. J.Comput.Aided Mol.Des., 26, 2012
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6GFI
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![BU of 6gfi by Molmil](/molmil-images/mine/6gfi) | Structure of Human Mesotrypsin in complex with APPI variant T11V/M17R/I18F/F34V | Descriptor: | 1,2-ETHANEDIOL, Amyloid-beta A4 protein, PRSS3 protein | Authors: | Shahar, A, Cohen, I, Radisky, E, Papo, N, Naftaly, S. | Deposit date: | 2018-04-30 | Release date: | 2018-09-12 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Mapping protein selectivity landscapes using multi-target selective screening and next-generation sequencing of combinatorial libraries. Nat Commun, 9, 2018
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6XYG
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![BU of 6xyg by Molmil](/molmil-images/mine/6xyg) | Femtosecond structure of bovine trypsin at room temperature | Descriptor: | BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... | Authors: | Jensen, M. | Deposit date: | 2020-01-30 | Release date: | 2021-02-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.50000238 Å) | Cite: | High-resolution macromolecular crystallography at the FemtoMAX beamline with time-over-threshold photon detection J.Synchrotron Radiat., 2021
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6AVL
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![BU of 6avl by Molmil](/molmil-images/mine/6avl) | Orthorhombic Trypsin (295 K) in the presence of 50% xylose | Descriptor: | BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... | Authors: | Juers, D.H. | Deposit date: | 2017-09-02 | Release date: | 2017-09-20 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The impact of cryosolution thermal contraction on proteins and protein crystals: volumes, conformation and order. Acta Crystallogr D Struct Biol, 74, 2018
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6B6R
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![BU of 6b6r by Molmil](/molmil-images/mine/6b6r) | Orthorhombic trypsin cryocooled to 100 K with 50% mpd as cryoprotectant | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, BENZAMIDINE, CALCIUM ION, ... | Authors: | Juers, D.H. | Deposit date: | 2017-10-03 | Release date: | 2017-11-01 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (2.00005865 Å) | Cite: | The impact of cryosolution thermal contraction on proteins and protein crystals: volumes, conformation and order. Acta Crystallogr D Struct Biol, 74, 2018
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6BFP
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![BU of 6bfp by Molmil](/molmil-images/mine/6bfp) | Bovine trypsin bound to potent inhibitor | Descriptor: | 3-{2-[(4-carbamimidoylphenyl)carbamoyl]-4-ethenyl-5-methoxyphenyl}-6-[(cyclopropylmethyl)carbamoyl]pyridine-2-carboxylic acid, CALCIUM ION, Cationic trypsin | Authors: | Partridge, J.R, Choy, R.M. | Deposit date: | 2017-10-26 | Release date: | 2018-10-31 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.292 Å) | Cite: | Structures of full-length plasma kallikrein bound to highly specific inhibitors describe a new mode of targeted inhibition. J.Struct.Biol., 206, 2019
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6B6Q
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![BU of 6b6q by Molmil](/molmil-images/mine/6b6q) | |
6B6N
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![BU of 6b6n by Molmil](/molmil-images/mine/6b6n) | Orthorhombic trypsin (295 K) in the presence of 50% mpd | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, BENZAMIDINE, CALCIUM ION, ... | Authors: | Juers, D.H. | Deposit date: | 2017-10-03 | Release date: | 2017-11-01 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The impact of cryosolution thermal contraction on proteins and protein crystals: volumes, conformation and order. Acta Crystallogr D Struct Biol, 74, 2018
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6B6T
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![BU of 6b6t by Molmil](/molmil-images/mine/6b6t) | |
6B6S
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![BU of 6b6s by Molmil](/molmil-images/mine/6b6s) | |
6B6O
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![BU of 6b6o by Molmil](/molmil-images/mine/6b6o) | |
6B6P
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![BU of 6b6p by Molmil](/molmil-images/mine/6b6p) | |
6DZF
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![BU of 6dzf by Molmil](/molmil-images/mine/6dzf) | |
2BY7
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![BU of 2by7 by Molmil](/molmil-images/mine/2by7) | Is radiation damage dependent on the dose-rate used during macromolecular crystallography data collection | Descriptor: | BENZAMIDINE, CALCIUM ION, CATIONIC TRYPSIN, ... | Authors: | Leiros, H.-K.S, Timmins, J, Ravelli, R.B.G, McSweeney, S.M. | Deposit date: | 2005-07-29 | Release date: | 2006-02-06 | Last modified: | 2021-08-04 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Is Radiation Damage Dependent on the Dose-Rate Used During Macromolecular Crystallography Data Collection? Acta Crystallogr.,Sect.D, 62, 2006
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2BYA
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![BU of 2bya by Molmil](/molmil-images/mine/2bya) | Is radiation damage dependent on the dose-rate used during macromolecular crystallography data collection | Descriptor: | BENZAMIDINE, CALCIUM ION, CATIONIC TRYPSIN, ... | Authors: | Leiros, H.-K.S, Timmins, J, Ravelli, R.B.G, McSweeney, S.M. | Deposit date: | 2005-07-29 | Release date: | 2006-02-06 | Last modified: | 2021-08-04 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Is Radiation Damage Dependent on the Dose-Rate Used During Macromolecular Crystallography Data Collection? Acta Crystallogr.,Sect.D, 62, 2006
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2BY6
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![BU of 2by6 by Molmil](/molmil-images/mine/2by6) | Is radiation damage dependent on the dose-rate used during macromolecular crystallography data collection | Descriptor: | BENZAMIDINE, CALCIUM ION, CATIONIC TRYPSIN, ... | Authors: | Leiros, H.-K.S, Timmins, J, Ravelli, R.B.G, McSweeney, S.M. | Deposit date: | 2005-07-29 | Release date: | 2006-02-06 | Last modified: | 2021-08-04 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Is Radiation Damage Dependent on the Dose-Rate Used During Macromolecular Crystallography Data Collection? Acta Crystallogr.,Sect.D, 62, 2006
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2BY9
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![BU of 2by9 by Molmil](/molmil-images/mine/2by9) | Is radiation damage dependent on the dose-rate used during macromolecular crystallography data collection | Descriptor: | BENZAMIDINE, CALCIUM ION, CATIONIC TRYPSIN, ... | Authors: | Leiros, H.-K.S, Timmins, J, Ravelli, R.B.G, McSweeney, S.M. | Deposit date: | 2005-07-29 | Release date: | 2006-02-06 | Last modified: | 2021-08-04 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Is Radiation Damage Dependent on the Dose-Rate Used During Macromolecular Crystallography Data Collection? Acta Crystallogr.,Sect.D, 62, 2006
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2BY8
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![BU of 2by8 by Molmil](/molmil-images/mine/2by8) | Is radiation damage dependent on the dose-rate used during macromolecular crystallography data collection | Descriptor: | BENZAMIDINE, CALCIUM ION, CATIONIC TRYPSIN, ... | Authors: | Leiros, H.-K.S, Timmins, J, Ravelli, R.B.G, McSweeney, S.M. | Deposit date: | 2005-07-29 | Release date: | 2006-02-06 | Last modified: | 2021-08-04 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Is Radiation Damage Dependent on the Dose-Rate Used During Macromolecular Crystallography Data Collection? Acta Crystallogr.,Sect.D, 62, 2006
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2BY5
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![BU of 2by5 by Molmil](/molmil-images/mine/2by5) | Is radiation damage dependent on the dose-rate used during macromolecular crystallography data collection | Descriptor: | BENZAMIDINE, CALCIUM ION, CATIONIC TRYPSIN, ... | Authors: | Leiros, H.-K.S, Timmins, J, Ravelli, R.B.G, McSweeney, S.M. | Deposit date: | 2005-07-29 | Release date: | 2006-02-06 | Last modified: | 2021-08-04 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Is Radiation Damage Dependent on the Dose-Rate Used During Macromolecular Crystallography Data Collection? Acta Crystallogr.,Sect.D, 62, 2006
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5XW1
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![BU of 5xw1 by Molmil](/molmil-images/mine/5xw1) | Crystal Structure of Porcine pancreatic trypsin with tripeptide inhibitor, PRN, at pH10 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Acetylated-Pro-Arg-Asn Inhibitor, CALCIUM ION, ... | Authors: | Saikhedkar, N.S, Bhoite, A.S, Giri, A.P, Kulkarni, K.A. | Deposit date: | 2017-06-28 | Release date: | 2018-07-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Reactive centre loop peptides devoid of potato protease inhibitor-II protein scaffold inhibit serine proteases To Be Published
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8I0J
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![BU of 8i0j by Molmil](/molmil-images/mine/8i0j) | JB13GH39P28 mutant-D41G | Descriptor: | CHLORIDE ION, Glycoside hydrolase family 39 beta-xylosidase | Authors: | Zhou, J.P, Cao, L.J, Lin, M.Y, Zhang, R, Huang, Z.X. | Deposit date: | 2023-01-11 | Release date: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | beta-Xylosidase JB13GH39P28 (D41G) showing salt/ethanol/trypsin tolerance and transformation of notoginsenosides To Be Published
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3GYM
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![BU of 3gym by Molmil](/molmil-images/mine/3gym) | Structure of Prostasin in Complex with Aprotinin | Descriptor: | Pancreatic trypsin inhibitor, Prostasin | Authors: | Spraggon, G, Hornsby, M, Shipway, A, Harris, J.L, Lesley, S.A. | Deposit date: | 2009-04-03 | Release date: | 2009-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations. Protein Sci., 18, 2009
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5JB4
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![BU of 5jb4 by Molmil](/molmil-images/mine/5jb4) | |