6HDB
 
 | | Crystal structure of the potassium channel MtTMEM175 with zinc | | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Nanobody,Maltose/maltodextrin-binding periplasmic protein, POTASSIUM ION, ... | | Authors: | Brunner, J.D, Jakob, R.P, Schulze, T, Neldner, Y, Moroni, A, Thiel, G, Maier, T, Schenck, S. | | Deposit date: | 2018-08-17 | | Release date: | 2019-08-28 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural basis for ion selectivity in TMEM175 K+channels.
Elife, 9, 2020
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8ILD
 | | The crystal structure of native dGTP:DNApre-I:Pol X substrate ternary complex | | Descriptor: | DNA (5'-D(*CP*AP*GP*GP*AP*TP*CP*CP*T)-3'), GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... | | Authors: | Qin, T, Chen, Y.Q, Gan, J.H, Huang, Z. | | Deposit date: | 2023-03-03 | | Release date: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structural Insight into Polymerase Mechanism via a Chiral Center Generated with a Single Selenium Atom.
Int J Mol Sci, 24, 2023
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6HGP
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8ILH
 | | The crystal structure of dG(Se-Sp)-DNA:Pol X product binary complex | | Descriptor: | 2'-DEOXYGUANOSINE-5'-MONOSELENOPHOSPHATE, DNA (5'-D(*CP*GP*GP*AP*TP*CP*C)-3'), MAGNESIUM ION, ... | | Authors: | Qin, T, Gan, J.H, Huang, Z. | | Deposit date: | 2023-03-03 | | Release date: | 2024-01-10 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural Insight into Polymerase Mechanism via a Chiral Center Generated with a Single Selenium Atom.
Int J Mol Sci, 24, 2023
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8ILI
 | | The crystal structure of dG(Se-Rp)-DNA:Pol X product binary complex | | Descriptor: | DNA (5'-D(*CP*GP*GP*AP*TP*CP*CP*(7S8))-3'), MAGNESIUM ION, Repair DNA polymerase X, ... | | Authors: | Qin, T, Gan, J.H, Huang, Z. | | Deposit date: | 2023-03-03 | | Release date: | 2024-01-10 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural Insight into Polymerase Mechanism via a Chiral Center Generated with a Single Selenium Atom.
Int J Mol Sci, 24, 2023
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6ZWM
 | | cryo-EM structure of human mTOR complex 2, overall refinement | | Descriptor: | ACETYL GROUP, INOSITOL HEXAKISPHOSPHATE, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Scaiola, A, Mangia, F, Imseng, S, Boehringer, D, Ban, N, Maier, T. | | Deposit date: | 2020-07-28 | | Release date: | 2020-11-18 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | The 3.2- angstrom resolution structure of human mTORC2.
Sci Adv, 6, 2020
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5GS2
 | | Crystal structure of diabody complex with repebody and MBP | | Descriptor: | Maltose-binding periplasmic protein, anti-MBP, anti-repebody, ... | | Authors: | Kim, J.H, Song, D.H, Youn, S.J, Kim, J.W, Cho, G, Lee, H, Lee, J.O. | | Deposit date: | 2016-08-13 | | Release date: | 2016-10-12 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.592 Å) | | Cite: | Crystal structure of mono- and bi-specific diabodies and reduction of their structural flexibility by introduction of disulfide bridges at the Fv interface.
Sci Rep, 6, 2016
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8ILE
 | | The crystal structure of dGTPalphaSe-Rp:DNApre-II:Pol X substrate ternary complex | | Descriptor: | DNA (5'-D(*CP*TP*GP*GP*AP*TP*CP*CP*A)-3'), MANGANESE (II) ION, Repair DNA polymerase X, ... | | Authors: | Qin, T, Gan, J.H, Huang, Z. | | Deposit date: | 2023-03-03 | | Release date: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural Insight into Polymerase Mechanism via a Chiral Center Generated with a Single Selenium Atom.
Int J Mol Sci, 24, 2023
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8ILG
 | | The crystal structure of dG-DNA:Pol X product binary complex | | Descriptor: | DNA (5'-D(*CP*GP*GP*AP*TP*CP*CP*G)-3'), FORMIC ACID, MANGANESE (II) ION, ... | | Authors: | Qin, T, Gan, J.H, Huang, Z. | | Deposit date: | 2023-03-03 | | Release date: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.805 Å) | | Cite: | Structural Insight into Polymerase Mechanism via a Chiral Center Generated with a Single Selenium Atom.
Int J Mol Sci, 24, 2023
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6HD9
 | | Crystal structure of the potassium channel MtTMEM175 with rubidium | | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Nanobody,Maltose/maltodextrin-binding periplasmic protein, RUBIDIUM ION, ... | | Authors: | Brunner, J.D, Jakob, R.P, Schulze, T, Neldner, Y, Moroni, A, Thiel, G, Maier, T, Schenck, S. | | Deposit date: | 2018-08-17 | | Release date: | 2019-08-28 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structural basis for ion selectivity in TMEM175 K+channels.
Elife, 9, 2020
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5AZ9
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4DN1
 | | Crystal structure of an ENOLASE (mandelate racemase subgroup member) from Agrobacterium tumefaciens (target EFI-502088) with bound mg and formate | | Descriptor: | CHLORIDE ION, FORMIC ACID, Isomerase/lactonizing enzyme, ... | | Authors: | Vetting, M.W, Toro, R, Bhosle, R, Bouvier, J.T, Wasserman, S.R, Morisco, L.L, Sojitra, S, Al Obaidi, N.F, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | | Deposit date: | 2012-02-08 | | Release date: | 2012-03-07 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Crystal structure of an enolase (mandelate racemase subgroup member) from Agrobacterium tumefaciens (target EFI-502088) with bound mg and formate
to be published
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8ILF
 | | The crystal structure of dGTPalphaSe-Sp:DNApre-II:Pol X substrate ternary complex | | Descriptor: | DNA (5'-D(*CP*TP*GP*GP*AP*TP*CP*CP*A)-3'), MANGANESE (II) ION, Repair DNA polymerase X, ... | | Authors: | Qin, T, Zhao, Q.W, Gan, J.H, Huang, Z. | | Deposit date: | 2023-03-03 | | Release date: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural Insight into Polymerase Mechanism via a Chiral Center Generated with a Single Selenium Atom.
Int J Mol Sci, 24, 2023
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5B3Y
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2OOW
 | | MIF Bound to a Fluorinated OXIM Derivative | | Descriptor: | 3-FLUORO-4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME, GLYCEROL, ISOPROPYL ALCOHOL, ... | | Authors: | Crichlow, G.V, Al-Abed, Y, Lolis, E. | | Deposit date: | 2007-01-26 | | Release date: | 2007-06-05 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor.
J.Biol.Chem., 282, 2007
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7RLU
 | | Structure of ALDH1L1 (10-formyltetrahydrofolate dehydrogenase) in complex with NADP | | Descriptor: | 4'-PHOSPHOPANTETHEINE, Cytosolic 10-formyltetrahydrofolate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Tsybovsky, Y, Sereda, V, Golczak, M, Krupenko, N.I, Krupenko, S.A. | | Deposit date: | 2021-07-26 | | Release date: | 2022-01-12 | | Last modified: | 2022-02-02 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structure of putative tumor suppressor ALDH1L1.
Commun Biol, 5, 2022
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7RLT
 | | Structure of ligand-free ALDH1L1 (10-formyltetrahydrofolate dehydrogenase) | | Descriptor: | 4'-PHOSPHOPANTETHEINE, Cytosolic 10-formyltetrahydrofolate dehydrogenase | | Authors: | Tsybovsky, Y, Sereda, V, Golczak, M, Krupenko, N.I, Krupenko, S.A. | | Deposit date: | 2021-07-26 | | Release date: | 2022-01-12 | | Last modified: | 2022-02-02 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structure of putative tumor suppressor ALDH1L1.
Commun Biol, 5, 2022
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4BLD
 | | Crystal structure of a human Suppressor of fused (SUFU)-GLI3p complex | | Descriptor: | MALTOSE-BINDING PERIPLASMIC PROTEIN, SUPPRESSOR OF FUSED HOMOLOG, TRANSCRIPTIONAL ACTIVATOR GLI3, ... | | Authors: | Cherry, A.L, Finta, C, Karlstrom, M, De Sanctis, D, Toftgard, R, Jovine, L. | | Deposit date: | 2013-05-02 | | Release date: | 2013-11-27 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.802 Å) | | Cite: | Structural Basis of Sufu-GLI Interaction in Hedgehog Signalling Regulation
Acta Crystallogr.,Sect.D, 69, 2013
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4BL8
 | | Crystal structure of full-length human Suppressor of fused (SUFU) | | Descriptor: | MALTOSE-BINDING PERIPLASMIC PROTEIN, SUPPRESSOR OF FUSED HOMOLOG, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | Authors: | Karlstrom, M, Finta, C, Cherry, A.L, Toftgard, R, Jovine, L. | | Deposit date: | 2013-05-02 | | Release date: | 2013-11-27 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.04 Å) | | Cite: | Structural Basis of Sufu-GLI Interaction in Hedgehog Signalling Regulation
Acta Crystallogr.,Sect.D, 69, 2013
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3MP8
 | | Crystal structure of Sgf29 tudor domain | | Descriptor: | 4-(HYDROXYMETHYL)BENZAMIDINE, ACETIC ACID, GLYCEROL, ... | | Authors: | Li, J, Wu, M, Ruan, J, Zang, J. | | Deposit date: | 2010-04-26 | | Release date: | 2011-05-04 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation
Embo J., 30, 2011
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3SEW
 | | Zn-mediated Polymer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form I) | | Descriptor: | CHLORIDE ION, GLYCEROL, Maltose-binding periplasmic protein, ... | | Authors: | Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O. | | Deposit date: | 2011-06-11 | | Release date: | 2011-09-21 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
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3N9X
 | | Crystal structure of Map Kinase from plasmodium berghei, PB000659.00.0 | | Descriptor: | GLYCEROL, Phosphotransferase | | Authors: | Wernimont, A.K, Hutchinson, A, Sullivan, H, MacKenzie, F, Kozieradzki, I, Chau, I, Lew, J, Senisterra, G, Artz, J, Amani, M, Cossar, D, Bochkarev, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Hui, R, Hills, T, Structural Genomics Consortium (SGC) | | Deposit date: | 2010-05-31 | | Release date: | 2010-07-28 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Crystal structure of Map Kinase from plasmodium berghei, PB000659.00.0
To be Published
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5EDU
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7TT7
 | | BamABCDE bound to substrate EspP in the barrelized EspP/continuous open BamA state | | Descriptor: | Maltose/maltodextrin-binding periplasmic protein,Serine protease EspP chimera, Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamC, ... | | Authors: | Doyle, M.T, Jimah, J.R, Dowdy, T, Ohlemacher, S.I, Larion, M, Hinshaw, J.E, Bernstein, H.D. | | Deposit date: | 2022-01-31 | | Release date: | 2022-03-30 | | Last modified: | 2022-04-13 | | Method: | ELECTRON MICROSCOPY (4.8 Å) | | Cite: | Cryo-EM structures reveal multiple stages of bacterial outer membrane protein folding.
Cell, 185, 2022
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7TT6
 | | BamABCDE bound to substrate EspP in the intermediate-open EspP state | | Descriptor: | Maltose/maltodextrin-binding periplasmic protein,Serine protease EspP chimera, Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamC, ... | | Authors: | Doyle, M.T, Jimah, J.R, Dowdy, T, Ohlemacher, S.I, Larion, M, Hinshaw, J.E, Bernstein, H.D. | | Deposit date: | 2022-01-31 | | Release date: | 2022-03-30 | | Last modified: | 2022-04-13 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Cryo-EM structures reveal multiple stages of bacterial outer membrane protein folding.
Cell, 185, 2022
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