8VKU
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![BU of 8vku by Molmil](/molmil-images/mine/8vku) | Structure of VCP in complex with an ATPase activator (D2 domains only, hexameric form) | Descriptor: | (3R)-N-[2-(ethylsulfanyl)phenyl]-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)butanamide, Transitional endoplasmic reticulum ATPase | Authors: | Jones, N.H, Urnivicius, L, Kapoor, T.M. | Deposit date: | 2024-01-09 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Allosteric activation of VCP, an AAA unfoldase, by small molecule mimicry. Proc.Natl.Acad.Sci.USA, 121, 2024
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8RN0
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8RN8
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![BU of 8rn8 by Molmil](/molmil-images/mine/8rn8) | Influenza B polymerase pseudo-symmetrical apo-dimer (FluPol(E)|FluPol(S)) | Descriptor: | MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ... | Authors: | Arragain, B, Cusack, S. | Deposit date: | 2024-01-09 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase. Nat Commun, 15, 2024
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8RNB
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![BU of 8rnb by Molmil](/molmil-images/mine/8rnb) | |
8RN4
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![BU of 8rn4 by Molmil](/molmil-images/mine/8rn4) | |
8RN1
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![BU of 8rn1 by Molmil](/molmil-images/mine/8rn1) | Influenza B polymerase, monomeric encapsidase with 5' cRNA hook bound | Descriptor: | 5' cRNA hook (1-12), Polymerase acidic protein, Polymerase basic protein 2, ... | Authors: | Arragain, B, Cusack, S. | Deposit date: | 2024-01-09 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.64 Å) | Cite: | Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase. Nat Commun, 15, 2024
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8RN6
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8RN2
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![BU of 8rn2 by Molmil](/molmil-images/mine/8rn2) | Monomeric apo-influenza B polymerase, encapsidase conformation | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit | Authors: | Arragain, B, Cusack, S. | Deposit date: | 2024-01-09 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase. Nat Commun, 15, 2024
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8RN7
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8RN5
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![BU of 8rn5 by Molmil](/molmil-images/mine/8rn5) | |
8RN3
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8RN9
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8RNA
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![BU of 8rna by Molmil](/molmil-images/mine/8rna) | Influenza B polymerase apo-trimer | Descriptor: | Acidic leucine-rich nuclear phosphoprotein 32 family member A, Polymerase acidic protein, Polymerase basic protein 2, ... | Authors: | Arragain, B, Cusack, S. | Deposit date: | 2024-01-09 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.57 Å) | Cite: | Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase. Nat Commun, 15, 2024
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8RNC
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![BU of 8rnc by Molmil](/molmil-images/mine/8rnc) | Influenza B polymerase, replication complex, an asymmetric polymerase dimer bound to human ANP32A (from "Influenza B polymerase apo-trimer" | Local refinement) | Descriptor: | Acidic leucine-rich nuclear phosphoprotein 32 family member A, Polymerase acidic protein, Polymerase basic protein 2, ... | Authors: | Arragain, B, Cusack, S. | Deposit date: | 2024-01-09 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase. Nat Commun, 15, 2024
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8VKR
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![BU of 8vkr by Molmil](/molmil-images/mine/8vkr) | CW Flagellar Switch Complex with extra density - FliF, FliG, FliM, and FliN forming the C-ring from Salmonella | Descriptor: | Flagellar M-ring protein, Flagellar motor switch protein FliG, Flagellar motor switch protein FliM, ... | Authors: | Singh, P.K, Iverson, T.M. | Deposit date: | 2024-01-09 | Release date: | 2024-02-28 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (5.9 Å) | Cite: | CryoEM structures reveal how the bacterial flagellum rotates and switches direction. Nat Microbiol, 9, 2024
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8VKQ
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![BU of 8vkq by Molmil](/molmil-images/mine/8vkq) | CW Flagellar Switch Complex - FliF, FliG, FliM, and FliN forming the C-ring from Salmonella | Descriptor: | Flagellar M-ring protein, Flagellar motor switch protein FliG, Flagellar motor switch protein FliM, ... | Authors: | Singh, P.K, Iverson, T.M. | Deposit date: | 2024-01-09 | Release date: | 2024-02-28 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | CryoEM structures reveal how the bacterial flagellum rotates and switches direction. Nat Microbiol, 9, 2024
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8VK3
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8VK4
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8RMO
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![BU of 8rmo by Molmil](/molmil-images/mine/8rmo) | Crystal structure of anti-FLAG M2 Fab fragment bound to FLAG-tag peptide epitope | Descriptor: | CHLORIDE ION, FLAG-tag, anti-FLAG M2 heavy chain, ... | Authors: | Beugelink, J.W, Janssen, B.J.C, Pronker, M.F. | Deposit date: | 2024-01-08 | Release date: | 2024-04-03 | Last modified: | 2024-07-03 | Method: | X-RAY DIFFRACTION (1.163 Å) | Cite: | Structural Basis for Recognition of the FLAG-tag by Anti-FLAG M2. J.Mol.Biol., 436, 2024
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8VKA
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![BU of 8vka by Molmil](/molmil-images/mine/8vka) | Crystal structure of Plasmodium vivax glycylpeptide N-tetradecanoyltransferase (N-myristoyltransferase, NMT) bound to myristoyl-CoA and inhibitor 9c | Descriptor: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CHLORIDE ION, GLYCEROL, ... | Authors: | Fenwick, M.K, Staker, B.L, Phan, I.Q, Early, J, Myler, P.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | Deposit date: | 2024-01-08 | Release date: | 2024-07-17 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Exploring Subsite Selectivity within Plasmodium vivax N -Myristoyltransferase Using Pyrazole-Derived Inhibitors. J.Med.Chem., 67, 2024
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8VKB
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![BU of 8vkb by Molmil](/molmil-images/mine/8vkb) | Crystal structure of Plasmodium vivax glycylpeptide N-tetradecanoyltransferase (N-myristoyltransferase, NMT) bound to myristoyl-CoA and inhibitor 10b | Descriptor: | CHLORIDE ION, GLYCEROL, Glycylpeptide N-tetradecanoyltransferase, ... | Authors: | Fenwick, M.K, Staker, B.L, Phan, I.Q, Early, J, Myler, P.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | Deposit date: | 2024-01-08 | Release date: | 2024-07-17 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Exploring Subsite Selectivity within Plasmodium vivax N -Myristoyltransferase Using Pyrazole-Derived Inhibitors. J.Med.Chem., 67, 2024
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8RMP
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![BU of 8rmp by Molmil](/molmil-images/mine/8rmp) | Influenza polymerase A/H7N9-4M (ENDO(R) | Core1) | Descriptor: | MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ... | Authors: | Arragain, B, Cusack, S. | Deposit date: | 2024-01-08 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.77 Å) | Cite: | Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase. Nat Commun, 15, 2024
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8RMQ
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![BU of 8rmq by Molmil](/molmil-images/mine/8rmq) | Influenza polymerase A/H7N9-4M (ENDO(R) | Core2) | Descriptor: | MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ... | Authors: | Arragain, B, Cusack, S. | Deposit date: | 2024-01-08 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.54 Å) | Cite: | Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase. Nat Commun, 15, 2024
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8RMS
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8VKD
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![BU of 8vkd by Molmil](/molmil-images/mine/8vkd) | Crystal structure of dehaloperoxidase A in complex with substrate 4-nitrocatechol | Descriptor: | 4-NITROCATECHOL, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... | Authors: | Aktar, M.S, de Serrano, V.S, Ghiladi, R.A, Franzen, S. | Deposit date: | 2024-01-08 | Release date: | 2024-07-17 | Last modified: | 2024-07-24 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural Comparison of Substrate Binding Sites in Dehaloperoxidase A and B. Biochemistry, 63, 2024
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