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1QP8	CRYSTAL STRUCTURE OF A PUTATIVE FORMATE DEHYDROGENASE FROM PYROBACULUM AEROPHILUM Descriptor: FORMATE DEHYDROGENASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Peat, T.S, Newman, J, Waldo, G.S, Terwilliger, T.C. Deposit date: 1999-06-01 Release date: 1999-06-11 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.8 Å) Cite: The Crystal Structure of a Putative Formate Dehydrogenase from Pyrobaculum Aerophilum To be Published
1WWK	Crystal structure of phosphoglycerate dehydrogenase from Pyrococcus horikoshii OT3 Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, phosphoglycerate dehydrogenase Authors: Sugahara, M, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2005-01-06 Release date: 2006-01-17 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of phosphoglycerate dehydrogenase from Pyrococcus horikoshii OT3 To be Published
5DNA	Crystal structure of Candida boidinii formate dehydrogenase Descriptor: FORMATE DEHYDROGENASE, SULFATE ION Authors: Guo, Q, Gakhar, L, Wichersham, K, Francis, K, Vardi-Kilshtain, A, Major, D.T, Cheatum, C.M, Kohen, A. Deposit date: 2015-09-09 Release date: 2016-05-04 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structural and Kinetic Studies of Formate Dehydrogenase from Candida boidinii. Biochemistry, 55, 2016
5DT9	Crystal structure of a putative D-Erythronate-4-Phosphate Dehydrogenase from Vibrio cholerae Descriptor: CHLORIDE ION, Erythronate-4-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... Authors: Stogios, P.J, Skarina, T, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2015-09-17 Release date: 2015-09-30 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.663 Å) Cite: Crystal structure of a putative D-Erythronate-4-Phosphate Dehydrogenase from Vibrio cholerae To Be Published
5DN9	Crystal structure of Candida boidinii formate dehydrogenase complexed with NAD+ and azide Descriptor: AZIDE ION, CHLORIDE ION, FDH, ... Authors: Guo, Q, Gakhar, L, Wichersham, K, Francis, K, Vardi-Kilshtain, A, Major, D.T, Cheatum, C.M, Kohen, A. Deposit date: 2015-09-09 Release date: 2016-05-04 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structural and Kinetic Studies of Formate Dehydrogenase from Candida boidinii. Biochemistry, 55, 2016
7CVP	The Crystal Structure of human PHGDH from Biortus. Descriptor: D-3-phosphoglycerate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Wang, F, Lv, Z, Cheng, W, Lin, D, Miao, Q, Huang, Y. Deposit date: 2020-08-26 Release date: 2020-09-09 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The Crystal Structure of human PHGDH from Biortus. To Be Published
1YBA	The active form of phosphoglycerate dehydrogenase Descriptor: 2-OXOGLUTARIC ACID, D-3-phosphoglycerate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... Authors: Thompson, J.R, Banaszak, L.J. Deposit date: 2004-12-20 Release date: 2005-04-26 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.24 Å) Cite: Vmax Regulation through Domain and Subunit Changes. The Active Form of Phosphoglycerate Dehydrogenase Biochemistry, 44, 2005
7YA3	Formate dehydrogenase from Novosphingobium sp. AP12 with NADP and Azide Descriptor: AZIDE ION, Formate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Kim, S, Kim, K.-J. Deposit date: 2022-06-27 Release date: 2023-07-12 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (3 Å) Cite: Dual cofactor specific formate dehydrogenase from Novosphingobium sp. AP12 with high activity. To Be Published
7YA4	Formate dehydrogenase from Novosphingobium sp. AP12 with NAD and Azide Descriptor: 1,2-ETHANEDIOL, ACETATE ION, AZIDE ION, ... Authors: Kim, S, Kim, K.-J. Deposit date: 2022-06-27 Release date: 2023-07-12 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Dual cofactor specific formate dehydrogenase from Novosphingobium sp. AP12 with high activity. To Be Published
8ARI	Cryo-EM structure of human CtBP1/RAI2(303-362) delta(331-341) filament Descriptor: C-terminal-binding protein 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Retinoic acid-induced protein 2 Authors: Mullapudi, E, Goradia, N, Wilmanns, M. Deposit date: 2022-08-16 Release date: 2023-08-23 Method: ELECTRON MICROSCOPY (3 Å) Cite: Cryo-EM structure of human CtBP1/RAI2(303-362) delta(331-341) filament To Be Published
8ATI	Human CtBP2(31-364) in complex with RAI2 peptide(315-322) Descriptor: DI(HYDROXYETHYL)ETHER, Isoform 2 of C-terminal-binding protein 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... Authors: Mullapudi, E, Goradia, N, Wilmanns, M. Deposit date: 2022-08-23 Release date: 2023-08-23 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Human CtBP2(31-364) in complex with RAI2 peptide(315-322) To Be Published
1YGY	Crystal Structure of D-3-Phosphoglycerate dehydrogenase From Mycobacterium tuberculosis Descriptor: D-3-phosphoglycerate dehydrogenase, L(+)-TARTARIC ACID Authors: Dey, S, Grant, G.A, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) Deposit date: 2005-01-05 Release date: 2005-01-25 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal Structure of Mycobacterium tuberculosis D-3-Phosphoglycerate Dehydrogenase: EXTREME ASYMMETRY IN A TETRAMER OF IDENTICAL SUBUNITS J.Biol.Chem., 280, 2005
3NAQ	Apo-form of NAD-dependent formate dehydrogenase from higher-plant Arabidopsis thaliana Descriptor: Formate dehydrogenase, SULFATE ION Authors: Shabalin, I.G, Polyakov, K.M, Serov, A.E, Skirgello, O.E, Sadykhov, E.G, Dorovatovskiy, P.V, Tishkov, V.I, Popov, V.O. Deposit date: 2010-06-02 Release date: 2010-07-07 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structures of the apo and holo forms of NAD-dependent formate dehydrogenase from the higher-plant Arabidopsis Thaliana to be published
2W2K	Crystal structure of the apo forms of Rhodotorula graminis D- mandelate dehydrogenase at 1.8A. Descriptor: D-MANDELATE DEHYDROGENASE Authors: Vachieri, S.G, Cole, A.R, Bagneris, C, Baker, D.P, Fewson, C.A, Basak, A.K. Deposit date: 2008-11-02 Release date: 2009-11-17 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Crystal Structure of the Apo and Holo Forms of Rhodotorula Graminis D(-)-Mandelate Dehydrogenase To be Published
3N7U	NAD-dependent formate dehydrogenase from higher-plant Arabidopsis thaliana in complex with NAD and azide Descriptor: AZIDE ION, Formate dehydrogenase, GLYCEROL, ... Authors: Shabalin, I.G, Polyakov, K.M, Serov, A.E, Skirgello, O.E, Sadykhov, E.G, Dorovatovskiy, P.V, Tishkov, V.I, Popov, V.O. Deposit date: 2010-05-27 Release date: 2010-06-09 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Structures of the apo and holo forms of NAD-dependent formate dehydrogenase from the higher-plant Arabidopsis Thaliana To be Published
8BXX	Crystal structure of formate dehydrogenase FDH2 enzyme from Granulicella mallensis MP5ACTX8 in complex with NAD and azide. Descriptor: 1,2-ETHANEDIOL, AZIDE ION, Formate dehydrogenase, ... Authors: Robescu, M.S, Rubini, R, Filippini, F, Bergantino, B, Cendron, L. Deposit date: 2022-12-10 Release date: 2023-01-18 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (1.97 Å) Cite: From the amelioration of a NADP+-dependent formate dehydrogenase to the discovery of a new enzyme: round trip from theory to practice ChemCatChem, 2020
7DKM	PHGDH covalently linked to oridonin Descriptor: (1beta,6beta,7beta,8alpha,9beta,10alpha,13alpha,14R,16beta)-1,6,7,14-tetrahydroxy-7,20-epoxykauran-15-one, CHLORIDE ION, D-3-phosphoglycerate dehydrogenase, ... Authors: Sun, Q, Lei, Y. Deposit date: 2020-11-25 Release date: 2022-02-02 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Biophysical and biochemical properties of PHGDH revealed by studies on PHGDH inhibitors. Cell.Mol.Life Sci., 79, 2021
2WWR	Crystal Structure of Human Glyoxylate Reductase Hydroxypyruvate Reductase Descriptor: GLYOXYLATE REDUCTASE/HYDROXYPYRUVATE REDUCTASE, MAGNESIUM ION Authors: Booth, M.P.S, Conners, R, Rumsby, G, Brady, R.L. Deposit date: 2009-10-26 Release date: 2010-10-13 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.82 Å) Cite: Structural Basis of Substrate Specificity in Human Glyoxylate Reductase/Hydroxypyruvate Reductase. J.Mol.Biol., 360, 2006
7WN9	Dictyostelium discoideum Lactate dehydrogenase (DicLDHA) Descriptor: ACETATE ION, Putative D-lactate dehydrogenase Authors: Dao, O, Lee, K.H. Deposit date: 2022-01-17 Release date: 2022-04-20 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Dictyostelium discoideum Lactate dehydrogenase (DicLDHA) To Be Published
2W2L	Crystal structure of the holo forms of Rhodotorula graminis D- mandelate dehydrogenase at 2.5A. Descriptor: D-MANDELATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION Authors: Vachieri, S.G, Cole, A.R, Bagneris, C, Baker, D.P, Fewson, C.A, Basak, A.K. Deposit date: 2008-11-02 Release date: 2009-11-17 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal Structure of the Apo and Holo Forms of Rhodotorula Graminis D(-)-Mandelate Dehydrogenase To be Published
7EWH	Crystal structure of human PHGDH in complex with Homoharringtonine Descriptor: (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, D-3-phosphoglycerate dehydrogenase Authors: Hsieh, C.H, Cheng, Y.S, Lee, Y.S, Huang, H.C, Juan, H.F. Deposit date: 2021-05-25 Release date: 2022-12-07 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.99 Å) Cite: Homoharringtonine as a PHGDH inhibitor: Unraveling metabolic dependencies and developing a potent therapeutic strategy for high-risk neuroblastoma. Biomed Pharmacother, 166, 2023
3OET	D-Erythronate-4-Phosphate Dehydrogenase complexed with NAD Descriptor: Erythronate-4-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Filippova, E.V, Wawrzak, Z, Onopriyenko, O, Savchenko, A, Edwards, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2010-08-13 Release date: 2010-08-25 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.36 Å) Cite: D-Erythronate-4-Phosphate Dehydrogenase complexed with NAD To be Published
6JX1	Crystal structure of Formate dehydrogenase mutant V198I/C256I/P260S/E261P/S381N/S383F from Pseudomonas sp. 101 Descriptor: Formate dehydrogenase, GLYCEROL Authors: Feng, Y, Xue, S, Guo, X, Zhao, Z. Deposit date: 2019-04-21 Release date: 2020-05-13 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.233 Å) Cite: Structure-Guided Design of Formate Dehydrogenase for Regeneration of a Non-Natural Redox Cofactor. Chemistry, 26, 2020
6JUK	Crystal structure of Formate dehydrogenase mutant C256I/E261P/S381I from Pseudomonas sp. 101 in complex with non-natural cofactor Nicotinamide Cytosine Dinucleotide Descriptor: Formate dehydrogenase, GLYCEROL, [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate Authors: Feng, Y, Xue, S, Guo, X, Zhao, Z. Deposit date: 2019-04-14 Release date: 2020-05-13 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.293 Å) Cite: Structure-Guided Design of Formate Dehydrogenase for Regeneration of a Non-Natural Redox Cofactor. Chemistry, 26, 2020
6JWG	Crystal structure of Formate dehydrogenase mutant C256I/E261P/S381I from Pseudomonas sp. 101 Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Formate dehydrogenase, GLYCEROL Authors: Feng, Y, Guo, X, Xue, S, Zhao, Z. Deposit date: 2019-04-20 Release date: 2020-05-13 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.081 Å) Cite: Structure-Guided Design of Formate Dehydrogenase for Regeneration of a Non-Natural Redox Cofactor. Chemistry, 26, 2020

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