PDB: 8697 resultsInfo pagesStatus searchChemie searchBIRD

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3AYH	Crystal structure of the C17/25 subcomplex from S. pombe RNA Polymerase III Descriptor: DNA-directed RNA polymerase III subunit rpc8, DNA-directed RNA polymerase III subunit rpc9, SULFATE ION Authors: Ehara, H, Sekine, S, Yokoyama, S. Deposit date: 2011-05-06 Release date: 2011-07-13 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.193 Å) Cite: Crystal structure of the C17/25 subcomplex from Schizosaccharomyces pombe RNA polymerase III Protein Sci., 20, 2011
7NVV	XPB-containing part of TFIIH in a post-translocated state (with ADP-BeF3) Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, General transcription and DNA repair factor IIH helicase subunit XPB, ... Authors: Aibara, S, Schilbach, S, Cramer, P. Deposit date: 2021-03-16 Release date: 2021-05-05 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
8JLB	Cryo-EM structure of the 145 bp human nucleosome containing H3.2 C110A mutant Descriptor: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... Authors: Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. Deposit date: 2023-06-02 Release date: 2023-10-04 Last modified: 2023-11-08 Method: ELECTRON MICROSCOPY (2.36 Å) Cite: Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II. Nucleic Acids Res., 51, 2023
8JL9	Cryo-EM structure of the human nucleosome with scFv Descriptor: DNA (193-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... Authors: Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. Deposit date: 2023-06-02 Release date: 2023-10-04 Last modified: 2023-11-08 Method: ELECTRON MICROSCOPY (2.65 Å) Cite: Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II. Nucleic Acids Res., 51, 2023
8JLD	Cryo-EM structure of the 145 bp human nucleosome containing acetylated H3 tail Descriptor: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... Authors: Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. Deposit date: 2023-06-02 Release date: 2023-10-04 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (2.48 Å) Cite: Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II. Nucleic Acids Res., 51, 2023
4YGX	Crystal Structure of D. melanogaster Ssu72+Symplekin bound to cis peptidomimetic CTD phospho-Ser5 peptide Descriptor: LD40846p, Symplekin, cis peptidomimetic CTD phospho-Ser5 peptide Authors: Mayfield, J.E, Zhang, Y. Deposit date: 2015-02-26 Release date: 2015-09-16 Last modified: 2015-10-28 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Chemical Tools To Decipher Regulation of Phosphatases by Proline Isomerization on Eukaryotic RNA Polymerase II. Acs Chem.Biol., 10, 2015
8JLA	Cryo-EM structure of the human nucleosome lacking N-terminal region of H2A, H2B, H3, and H4 Descriptor: DNA (193-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... Authors: Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. Deposit date: 2023-06-02 Release date: 2023-10-04 Last modified: 2023-11-08 Method: ELECTRON MICROSCOPY (3.44 Å) Cite: Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II. Nucleic Acids Res., 51, 2023
5MDT	Structure of the CTD-interacting domain (CID) of Seb1 from S. pombe. Descriptor: Rpb7-binding protein seb1 Authors: Wittmann, S, Renner, M, Vasiljeva, L, Grimes, J. Deposit date: 2016-11-13 Release date: 2017-04-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.62 Å) Cite: The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA. Nat Commun, 8, 2017
2EC0	RNA-dependent RNA polymerase of foot-and-mouth disease virus in complex with a template-primer RNA and ATP Descriptor: 5'-R(*GP*GP*GP*CP*CP*CP*A)-3', 5'-R(P*AP*UP*GP*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ... Authors: Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. Deposit date: 2007-02-09 Release date: 2007-06-26 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Sequential structures provide insights into the fidelity of RNA replication Proc.Natl.Acad.Sci.Usa, 104, 2007
1NB7	HC-J4 RNA polymerase complexed with short RNA template strand Descriptor: 5'-R(*UP*UP*UP*U)-3', MANGANESE (II) ION, polyprotein Authors: O'Farrell, D.J, Trowbridge, R, Rowlands, D.J, Jaeger, J. Deposit date: 2002-12-02 Release date: 2003-03-25 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Substrate complexes of hepatitis C virus RNA polymerase (HC-J4): structural evidence for nucleotide import and de-novo initiation. J.Mol.Biol., 326, 2003
7KKF	Crystal Structure of S. cerevisiae Ess1 Descriptor: Peptidyl-prolyl cis-trans isomerase ESS1 Authors: Namitz, K.E.W, Alicea-Velazquez, N.L, Cosgrove, M.S, Hanes, S.D. Deposit date: 2020-10-27 Release date: 2021-03-31 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structure analysis suggests Ess1 isomerizes the carboxy-terminal domain of RNA polymerase II via a bivalent anchoring mechanism. Commun Biol, 4, 2021
2O5J	Crystal structure of the T. thermophilus RNAP polymerase elongation complex with the NTP substrate analog Descriptor: 5'-D(*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*AP*GP*GP*G)-3', 5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP*CP*GP*CP*CP*G)-3', 5'-R(P*GP*AP*GP*UP*CP*UP*GP*CP*GP*GP*CP*GP*CP*GP*CP*G)-3', ... Authors: Vassylyev, D.G, Vassylyeva, M.N. Deposit date: 2006-12-06 Release date: 2007-07-03 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural basis for substrate loading in bacterial RNA polymerase. Nature, 448, 2007
2PPB	Crystal structure of the T. thermophilus RNAP polymerase elongation complex with the ntp substrate analog and antibiotic streptolydigin Descriptor: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA (5'-D(*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*AP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP*CP*GP*CP*CP*G)-3'), ... Authors: Vassylyev, D.G, Vassylyeva, M.N, Artsimovitch, I, Landick, R. Deposit date: 2007-04-28 Release date: 2007-07-17 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural basis for substrate loading in bacterial RNA polymerase. Nature, 448, 2007
2WHO	CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE FROM 1B GENOTYPE IN COMPLEX WITH A NON-NUCLEOSIDE INHIBITOR Descriptor: 2-(3-bromophenyl)-6-[(2-hydroxyethyl)amino]-1h-benzo[de]isoquinoline-1,3(2h)-dione, MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE Authors: Di Marco, S. Deposit date: 2009-05-05 Release date: 2009-08-11 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Identification and biological evaluation of a series of 1H-benzo[de]isoquinoline-1,3(2H)-diones as hepatitis C virus NS5B polymerase inhibitors. J. Med. Chem., 52, 2009
1NB6	HC-J4 RNA polymerase complexed with UTP Descriptor: MANGANESE (II) ION, URIDINE 5'-TRIPHOSPHATE, polyprotein Authors: O'Farrell, D.J, Trowbridge, R, Rowlands, D.J, Jaeger, J. Deposit date: 2002-12-02 Release date: 2003-03-25 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Substrate complexes of hepatitis C virus RNA polymerase (HC-J4): structural evidence for nucleotide import and de-novo initiation. J.Mol.Biol., 326, 2003
6IRV	Crystal structure of the human cap-specific adenosine methyltransferase Descriptor: Phosphorylated CTD-interacting factor 1 Authors: Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. Deposit date: 2018-11-14 Release date: 2018-12-05 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase. Science, 363, 2019
6IRX	Crystal structure of the zebrafish cap-specific adenosine methyltransferase Descriptor: PDX1 C-terminal-inhibiting factor 1 Authors: Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. Deposit date: 2018-11-14 Release date: 2018-12-05 Last modified: 2020-10-28 Method: X-RAY DIFFRACTION (2 Å) Cite: Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase. Science, 363, 2019
6IRY	Crystal structure of the zebrafish cap-specific adenosine methyltransferase bound to SAH Descriptor: 1,2-ETHANEDIOL, PDX1 C-terminal-inhibiting factor 1, S-ADENOSYL-L-HOMOCYSTEINE Authors: Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. Deposit date: 2018-11-14 Release date: 2018-12-05 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase. Science, 363, 2019
6IRW	Crystal structure of the human cap-specific adenosine methyltransferase bound to SAH Descriptor: Phosphorylated CTD-interacting factor 1, S-ADENOSYL-L-HOMOCYSTEINE Authors: Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. Deposit date: 2018-11-14 Release date: 2018-12-05 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase. Science, 363, 2019
2O5I	Crystal structure of the T. thermophilus RNA polymerase elongation complex Descriptor: 5'-D(*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*AP*GP*GP*G)-3', 5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP*CP*GP*CP*CP*G)-3', 5'-R(P*GP*AP*GP*UP*CP*UP*GP*CP*GP*GP*CP*GP*CP*GP*CP*G)-3', ... Authors: Vassylyev, D.G, Tahirov, T.H, Vassylyeva, M.N. Deposit date: 2006-12-06 Release date: 2007-07-03 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural basis for transcription elongation by bacterial RNA polymerase. Nature, 448, 2007
1YV2	Hepatitis C virus NS5B RNA-dependent RNA Polymerase genotype 2a Descriptor: GLYCEROL, RNA dependent RNA polymerase, SULFATE ION Authors: Biswal, B.K, Cherney, M.M, Wang, M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Nicolas, O, Bedard, J, James, M.N.G. Deposit date: 2005-02-14 Release date: 2005-03-22 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal Structures of the RNA-dependent RNA Polymerase Genotype 2a of Hepatitis C Virus Reveal Two Conformations and Suggest Mechanisms of Inhibition by Non-nucleoside Inhibitors J.Biol.Chem., 280, 2005
2A69	Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with antibiotic rifapentin Descriptor: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... Authors: Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2005-07-02 Release date: 2005-09-20 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
2A68	Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic rifabutin Descriptor: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... Authors: Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2005-07-01 Release date: 2005-09-20 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
2BF0	crystal structure of the rpr of pcf11 Descriptor: CALCIUM ION, PCF11 Authors: Noble, C.G, Hollingworth, D, Martin, S.R, Adeniran, V.E, Smerdon, S.J, Kelly, G, Taylor, I.A, Ramos, A. Deposit date: 2004-12-02 Release date: 2005-01-18 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Key Features of the Interaction between Pcf11 Cid and RNA Polymerase II Ctd. Nat.Struct.Mol.Biol., 12, 2005
6FO1	Human R2TP subcomplex containing 1 RUVBL1-RUVBL2 hexamer bound to 1 RBD domain from RPAP3. Descriptor: ADENOSINE-5'-DIPHOSPHATE, RNA polymerase II-associated protein 3, RuvB-like 1, ... Authors: Martino, F, Munoz-Hernandez, H, Rodriguez, C.F, Pearl, L.H, Llorca, O. Deposit date: 2018-02-05 Release date: 2018-04-04 Last modified: 2019-12-11 Method: ELECTRON MICROSCOPY (3.57 Å) Cite: RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex. Nat Commun, 9, 2018

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