3HG0
 
 | | Crystal structure of a DARPin in complex with ORF49 from Lactococcal phage TP901-1 | | Descriptor: | Baseplate protein, Designed Ankyrin Repeat Protein (DARPin) 20 | | Authors: | Veesler, D, Dreier, B, Blangy, S, Lichiere, J, Tremblay, D, Moineau, S, Spinelli, S, Tegoni, M, Pluckthun, A, Campanacci, V, Cambillau, C. | | Deposit date: | 2009-05-13 | | Release date: | 2009-09-08 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure and function of a DARPin neutralizing inhibitor of lactococcal phage TP901-1: comparison of DARPin and camelid VHH binding mode.
J.Biol.Chem., 284, 2009
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2W8V
 | | SPT with PLP, N100W | | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, SERINE PALMITOYLTRANSFERASE | | Authors: | Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H. | | Deposit date: | 2009-01-19 | | Release date: | 2009-01-27 | | Last modified: | 2015-11-18 | | Method: | X-RAY DIFFRACTION (1.43 Å) | | Cite: | The External-Aldimine Form of Serine Palmitoyltranserase; Structural, Kinetic and Spectroscopic Analysis of the Wild-Type Enzyme and Hsan1 Mutant Mimics.
J.Biol.Chem., 284, 2009
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3FAJ
 | | Structure of the structural protein P131 of the archaeal virus Acidianus Two-tailed virus (ATV) | | Descriptor: | CHLORIDE ION, Putative uncharacterized protein | | Authors: | Goulet, A, Vestergaard, G, Scheele, U, Campanacci, V, Garrett, R.A, Cambillau, C. | | Deposit date: | 2008-11-17 | | Release date: | 2009-11-24 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure of the structural protein P131 of the archaeal virus Acidianus Two-tailed virus (ATV)
To be Published
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3FBZ
 | | Crystal structure of ORF140 of the archaeal virus Acidianus Filamentous Virus 1 (AFV1) | | Descriptor: | CHLORIDE ION, Putative uncharacterized protein, octyl beta-D-glucopyranoside | | Authors: | Goulet, A, Prangishvili, D, van Tilbeurgh, H, Campanacci, V, Cambillau, C. | | Deposit date: | 2008-11-20 | | Release date: | 2009-11-10 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Acidianus filamentous virus 1 coat proteins display a helical fold spanning the filamentous archaeal viruses lineage.
Proc.Natl.Acad.Sci.USA, 106, 2009
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2W1A
 | | Non-covalent complex between dahp synthase and chorismate mutase from Mycobacterium tuberculosis with bound tsa | | Descriptor: | 3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE AROG, 8-HYDROXY-2-OXA-BICYCLO[3.3.1]NON-6-ENE-3,5-DICARBOXYLIC ACID, CHORISMATE MUTASE, ... | | Authors: | Okvist, M, Sasso, S, Roderer, K, Gamper, M, Codoni, G, Krengel, U, Kast, P. | | Deposit date: | 2008-10-16 | | Release date: | 2009-07-07 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structure and Function of a Complex between Chorismate Mutase and Dahp Synthase: Efficiency Boost for the Junior Partner.
Embo J., 28, 2009
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3FA2
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2R9F
 | | Calpain 1 proteolytic core inactivated by ZLAK-3002, an alpha-ketoamide | | Descriptor: | CALCIUM ION, CHLORIDE ION, Calpain-1 catalytic subunit, ... | | Authors: | Qian, J, Campbell, R.L, Davies, P.L. | | Deposit date: | 2007-09-12 | | Release date: | 2008-08-26 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Cocrystal structures of primed side-extending alpha-ketoamide inhibitors reveal novel calpain-inhibitor aromatic interactions.
J.Med.Chem., 51, 2008
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3HCS
 | | Crystal structure of the N-terminal domain of TRAF6 | | Descriptor: | TNF receptor-associated factor 6, ZINC ION | | Authors: | Yin, Q, Lin, S.-C, Lamothe, B, Lu, M, Lo, Y.-C, Hura, G, Zheng, L, Rich, R.L, Campos, A.D, Myszka, D.G, Lenardo, M.J, Darnay, B.G, Wu, H. | | Deposit date: | 2009-05-06 | | Release date: | 2009-05-26 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | E2 interaction and dimerization in the crystal structure of TRAF6.
Nat.Struct.Mol.Biol., 16, 2009
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3GUV
 | | Crystal structure of a resolvase family site-specific recombinase from Streptococcus pneumoniae | | Descriptor: | Site-specific recombinase, resolvase family protein | | Authors: | Bonanno, J.B, Freeman, J, Bain, K.T, Do, J, Sampathkumar, P, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2009-03-30 | | Release date: | 2009-04-07 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of a resolvase family site-specific recombinase from Streptococcus pneumoniae
To be Published
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3GUY
 | | Crystal structure of a short-chain dehydrogenase/reductase from Vibrio parahaemolyticus | | Descriptor: | Short-chain dehydrogenase/reductase SDR | | Authors: | Patskovsky, Y, Bonanno, J.B, Freeman, J, Bain, K.T, Miller, S, Sampathkumar, P, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2009-03-30 | | Release date: | 2009-04-14 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of a short-chain dehydrogenase/reductase from Vibrio parahaemolyticus
To be Published
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2W2F
 | | CRYSTAL STRUCTURE OF SINGLE POINT MUTANT ARG48GLN OF P-COUMARIC ACID DECARBOXYLASE FROM LACTOBACILLUS PLANTARUM STRUCTURAL INSIGHTS INTO THE ACTIVE SITE AND DECARBOXYLATION CATALYTIC MECHANISM | | Descriptor: | BARIUM ION, P-COUMARIC ACID DECARBOXYLASE | | Authors: | Rodriguez, H, Angulo, I, De Las Rivas, B, Campillo, N, Paez, J.A, Munoz, R, Mancheno, J.M. | | Deposit date: | 2008-10-29 | | Release date: | 2010-02-09 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | P-Coumaric Acid Decarboxylase from Lactobacillus Plantarum: Structural Insights Into the Active Site and Decarboxylation Catalytic Mechanism.
Proteins, 78, 2010
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1CC2
 | | CHOLESTEROL OXIDASE FROM STREPTOMYCES HIS447GLN MUTANT | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, PROTEIN (CHOLESTEROL OXIDASE) | | Authors: | Vrielink, A, Yue, Q.K. | | Deposit date: | 1999-03-03 | | Release date: | 1999-03-11 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure determination of cholesterol oxidase from Streptomyces and structural characterization of key active site mutants.
Biochemistry, 38, 1999
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2W8J
 | | SPT with PLP-ser | | Descriptor: | SERINE PALMITOYLTRANSFERASE, [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE | | Authors: | Carter, L.G, Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H. | | Deposit date: | 2009-01-16 | | Release date: | 2009-01-27 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The External-Aldimine Form of Serine Palmitoyltranserase; Structural, Kinetic and Spectroscopic Analysis of the Wild-Type Enzyme and Hsan1 Mutant Mimics.
J.Biol.Chem., 284, 2009
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2VZG
 | | Crystal structure of the C-terminal calponin homology domain of alpha- parvin in complex with paxillin LD2 motif | | Descriptor: | 1,2-ETHANEDIOL, Alpha-parvin, Paxillin, ... | | Authors: | Lorenz, S, Vakonakis, I, Lowe, E.D, Campbell, I.D, Noble, M.E.M, Hoellerer, M.K. | | Deposit date: | 2008-08-01 | | Release date: | 2008-10-28 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural analysis of the interactions between paxillin LD motifs and alpha-parvin.
Structure, 16, 2008
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2W8T
 | | SPT with PLP, N100C | | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, SERINE PALMITOYLTRANSFERASE | | Authors: | Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H. | | Deposit date: | 2009-01-19 | | Release date: | 2009-01-27 | | Last modified: | 2015-11-18 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | The External-Aldimine Form of Serine Palmitoyltranserase; Structural, Kinetic and Spectroscopic Analysis of the Wild-Type Enzyme and Hsan1 Mutant Mimics.
J.Biol.Chem., 284, 2009
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3IGE
 | | Small outer capsid protein (Soc) from bacteriophage RB69 | | Descriptor: | IMIDAZOLE, Soc small outer capsid protein | | Authors: | Li, Q, Fokine, A, O'Donnell, E, Rao, V.B, Rossmann, M.G. | | Deposit date: | 2009-07-27 | | Release date: | 2009-12-08 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.254 Å) | | Cite: | Structure of the Small Outer Capsid Protein, Soc: A Clamp for Stabilizing Capsids of T4-like Phages
J.Mol.Biol., 395, 2010
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3IP2
 | | Crystal structure of red fluorescent protein Neptune at pH 7.0 | | Descriptor: | Neptune red fluorescent protein | | Authors: | Lin, M.Z, McKeown, M.R, Ng, H.L, Aguilera, T.A, Shaner, N.C, Ma, W, Adams, S.R, Campbell, R.E, Alber, T, Tsien, R.Y. | | Deposit date: | 2009-08-15 | | Release date: | 2009-12-15 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Autofluorescent proteins with excitation in the optical window for intravital imaging in mammals.
Chem.Biol., 16, 2009
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1OTS
 | | Structure of the Escherichia coli ClC Chloride channel and Fab Complex | | Descriptor: | CHLORIDE ION, Fab fragment (heavy chain), Fab fragment (light chain), ... | | Authors: | Dutzler, R, Campbell, E.B, MacKinnon, R. | | Deposit date: | 2003-03-22 | | Release date: | 2003-04-15 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | Gating the Selectivity Filter in ClC Chloride Channels
Science, 300, 2003
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1B4V
 | | CHOLESTEROL OXIDASE FROM STREPTOMYCES | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, PROTEIN (CHOLESTEROL OXIDASE) | | Authors: | Vrielink, A, Yue, Q.K. | | Deposit date: | 1998-12-30 | | Release date: | 1999-01-06 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal structure determination of cholesterol oxidase from Streptomyces and structural characterization of key active site mutants.
Biochemistry, 38, 1999
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2VZD
 | | Crystal structure of the C-terminal calponin homology domain of alpha parvin in complex with paxillin LD1 motif | | Descriptor: | 1,2-ETHANEDIOL, ALPHA-PARVIN, GLYCEROL, ... | | Authors: | Lorenz, S, Vakonakis, I, Lowe, E.D, Campbell, I.D, Noble, M.E.M, Hoellerer, M.K. | | Deposit date: | 2008-07-31 | | Release date: | 2008-10-28 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural Analysis of the Interactions between Paxillin Ld Motifs and Alpha-Parvin
Structure, 16, 2008
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4HW3
 | | Discovery of potent Mcl-1 inhibitors using fragment-based methods and structure-based design | | Descriptor: | 3-[3-(4-chloro-3,5-dimethylphenoxy)propyl]-1-benzothiophene-2-carboxylic acid, Induced myeloid leukemia cell differentiation protein Mcl-1 | | Authors: | Zhao, B. | | Deposit date: | 2012-11-07 | | Release date: | 2013-01-09 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Discovery of potent myeloid cell leukemia 1 (Mcl-1) inhibitors using fragment-based methods and structure-based design.
J.Med.Chem., 56, 2013
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4HW4
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3ILD
 | | Structure of ORF157-K57A from Acidianus filamentous virus 1 | | Descriptor: | MAGNESIUM ION, Putative uncharacterized protein | | Authors: | Goulet, A, Lichiere, J, Prangishvili, D, van Tilbeurgh, H, Cambillau, C, Campanacci, V. | | Deposit date: | 2009-08-07 | | Release date: | 2010-03-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | ORF157 from the archaeal virus Acidianus filamentous virus 1 defines a new class of nuclease
J.Virol., 84, 2010
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2W8U
 | | SPT with PLP, N100Y | | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, SERINE PALMITOYLTRANSFERASE | | Authors: | Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H. | | Deposit date: | 2009-01-19 | | Release date: | 2009-01-27 | | Last modified: | 2015-11-18 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The External-Aldimine Form of Serine Palmitoyltranserase; Structural, Kinetic and Spectroscopic Analysis of the Wild-Type Enzyme and Hsan1 Mutant Mimics.
J.Biol.Chem., 284, 2009
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1OTU
 | | Structure of the Escherichia coli ClC Chloride channel E148Q mutant and Fab Complex | | Descriptor: | CHLORIDE ION, Fab fragment (Heavy chain), Fab fragment (Light chain), ... | | Authors: | Dutzler, R, Campbell, E.B, MacKinnon, R. | | Deposit date: | 2003-03-23 | | Release date: | 2003-04-15 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Gating the Selectivity Filter in ClC Chloride Channels
Science, 300, 2003
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