8TSY
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7C48
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4V24
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![BU of 4v24 by Molmil](/molmil-images/mine/4v24) | Sphingosine kinase 1 in complex with PF-543 | Descriptor: | ACETATE ION, SPHINGOSINE KINASE 1, {(2R)-1-[4-({3-METHYL-5-[(PHENYLSULFONYL)METHYL]PHENOXY}METHYL)BENZYL]PYRROLIDIN-2-YL}METHANOL | Authors: | Elkins, J.M, Wang, J, Sorrell, F, Tallant, C, Wang, D, Shrestha, L, Bountra, C, von Delft, F, Knapp, S, Edwards, A. | Deposit date: | 2014-10-05 | Release date: | 2014-10-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of Sphingosine Kinase 1 with Pf-543. Acs Med.Chem.Lett., 5, 2014
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4USA
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![BU of 4usa by Molmil](/molmil-images/mine/4usa) | Aldehyde Oxidoreductase from Desulfovibrio gigas (MOP), soaked with trans-cinnamaldehyde | Descriptor: | (MOLYBDOPTERIN-CYTOSINE DINUCLEOTIDE-S,S)-DIOXO-AQUA-MOLYBDENUM(V), ALDEHYDE OXIDOREDUCTASE, BICARBONATE ION, ... | Authors: | Correia, H.D, Romao, M.J, Santos-Silva, T. | Deposit date: | 2014-07-03 | Release date: | 2014-10-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.13 Å) | Cite: | Aromatic Aldehydes at the Active Site of Aldehyde Oxidoreductase from Desulfovibrio Gigas: Reactivity and Molecular Details of the Enzyme-Substrate and Enzyme-Product Interaction. J.Biol.Inorg.Chem., 20, 2015
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7C46
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4UW4
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![BU of 4uw4 by Molmil](/molmil-images/mine/4uw4) | Human galectin-7 in complex with a galactose based dendron D2-1. | Descriptor: | DENDRON D2-1, GALECTIN-7 | Authors: | Ramaswamy, S, Sleiman, M.H, Masuyer, G, Arbez-Gindre, C, Micha-Screttas, M, Calogeropoulou, T, Steele, B.R, Acharya, K.R. | Deposit date: | 2014-08-08 | Release date: | 2014-11-12 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.766 Å) | Cite: | Structural Basis of Multivalent Galactose-Based Dendrimer Recognition by Human Galectin-7. FEBS J., 282, 2015
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4UYZ
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4USO
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![BU of 4uso by Molmil](/molmil-images/mine/4uso) | X-ray structure of the CCL2 lectin in complex with sialyl lewis X | Descriptor: | CCL2 LECTIN, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Bleuler-Martinez, S, Varrot, A, Schubert, M, Stutz, M, Sieber, R, Hengartner, M, Aebi, M, Kunzler, M. | Deposit date: | 2014-07-11 | Release date: | 2015-07-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Dimerization of the fungal defense lectin CCL2 is essential for its toxicity against nematodes. Glycobiology, 27, 2017
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7C8L
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![BU of 7c8l by Molmil](/molmil-images/mine/7c8l) | Hybrid designing of potent inhibitors of Striga strigolactone receptor ShHTL7 | Descriptor: | 2-(2-{2-[2-(2-{2-[2-(2-{2-[4-(1,1,3,3-TETRAMETHYL-BUTYL)-PHENOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOX Y}-ETHOXY)-ETHANOL, GLYCEROL, Hyposensitive to light 7, ... | Authors: | Shahul Hameed, U.F, Arold, S.T. | Deposit date: | 2020-06-02 | Release date: | 2021-06-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Rational design of Striga hermonthica-specific seed germination inhibitors. Plant Physiol., 188, 2022
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4UW7
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![BU of 4uw7 by Molmil](/molmil-images/mine/4uw7) | Structure of the carboxy-terminal domain of the bacteriophage T5 L- shaped tail fiber without its intra-molecular chaperone domain | Descriptor: | GLYCEROL, L-SHAPED TAIL FIBER PROTEIN | Authors: | Garcia-Doval, C, Luque, D, Caston, J.R, Otero, J.M, Llamas-Saiz, A.L, Boulanger, P, van Raaij, M.J. | Deposit date: | 2014-08-08 | Release date: | 2015-08-05 | Last modified: | 2018-01-17 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Structure of the Receptor-Binding Carboxy-Terminal Domain of the Bacteriophage T5 L-Shaped Tail Fibre with and without Its Intra-Molecular Chaperone. Viruses, 7, 2015
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4V2K
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![BU of 4v2k by Molmil](/molmil-images/mine/4v2k) | Crystal structure of the thiosulfate dehydrogenase TsdA in complex with thiosulfate | Descriptor: | HEME C, THIOSULFATE, THIOSULFATE DEHYDROGENASE | Authors: | Grabarczyk, D.B, Chappell, P.E, Eisel, B, Johnson, S, Lea, S.M, Berks, B.C. | Deposit date: | 2014-10-10 | Release date: | 2015-02-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.29 Å) | Cite: | Mechanism of Thiosulfate Oxidation in the Soxa Family of Cysteine-Ligated Cytochromes J.Biol.Chem., 290, 2015
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7C91
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![BU of 7c91 by Molmil](/molmil-images/mine/7c91) | Blasnase-T13A with D-asn | Descriptor: | D-ASPARAGINE, FORMIC ACID, L-asparaginase, ... | Authors: | Lu, F, Ran, T, Jiao, L, Wang, W. | Deposit date: | 2020-06-04 | Release date: | 2021-06-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structures of l-asparaginase from Bacillus licheniformis Reveal an Essential Residue for its Substrate Stereoselectivity. J.Agric.Food Chem., 69, 2021
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7CB4
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![BU of 7cb4 by Molmil](/molmil-images/mine/7cb4) | Crystal structures of of BlAsnase | Descriptor: | FORMIC ACID, GLYCEROL, L-asparaginase, ... | Authors: | Lu, F, Ran, T, Jiao, L, Wang, W. | Deposit date: | 2020-06-10 | Release date: | 2021-06-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Structures of l-asparaginase from Bacillus licheniformis Reveal an Essential Residue for its Substrate Stereoselectivity. J.Agric.Food Chem., 69, 2021
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4UQZ
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![BU of 4uqz by Molmil](/molmil-images/mine/4uqz) | Coevolution of the ATPase ClpV, the TssB-TssC Sheath and the Accessory HsiE Protein Distinguishes Two Type VI Secretion Classes | Descriptor: | ACETATE ION, HSIB1, HSIE1 | Authors: | Forster, A, Planamente, S, Manoli, E, Lossi, N.S, Freemont, P.S, Filloux, A. | Deposit date: | 2014-06-25 | Release date: | 2014-10-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.599 Å) | Cite: | Coevolution of the ATPase Clpv, the Sheath Proteins Tssb and Tssc and the Accessory Protein Tagj/Hsie1 Distinguishes Type Vi Secretion Classes. RNA, 20, 2014
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7CC2
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4UT3
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![BU of 4ut3 by Molmil](/molmil-images/mine/4ut3) | X-ray structure of the human PP1 gamma catalytic subunit treated with hydrogen peroxide | Descriptor: | MANGANESE (II) ION, PHOSPHATE ION, SERINE/THREONINE-PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUBUNIT | Authors: | Zeh Silva, M, Kopec, J, Fotinou, D, Steiner, R.A. | Deposit date: | 2014-07-17 | Release date: | 2015-07-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Targeted Redox Inhibition of Protein Phosphatase 1 by Nox4 Regulates Eif2Alpha-Mediated Stress Signaling. Embo J., 35, 2016
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7C9B
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![BU of 7c9b by Molmil](/molmil-images/mine/7c9b) | Crystal structure of dipeptidase-E from Xenopus laevis | Descriptor: | Alpha-aspartyl dipeptidase, CALCIUM ION, SODIUM ION | Authors: | Kumar, A, Singh, R, Makde, R.D. | Deposit date: | 2020-06-05 | Release date: | 2021-06-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structure of aspartyl dipeptidase from Xenopus laevis revealed ligand binding induced loop ordering and catalytic triad assembly. Proteins, 90, 2022
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4UT2
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![BU of 4ut2 by Molmil](/molmil-images/mine/4ut2) | X-ray structure of the human PP1 gamma catalytic subunit treated with ascorbate | Descriptor: | MANGANESE (II) ION, PHOSPHATE ION, SERINE/THREONINE-PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUBUNIT | Authors: | Kopec, J, Zeh Silva, M, Fotinou, C, Steiner, R.A. | Deposit date: | 2014-07-17 | Release date: | 2015-07-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Targeted Redox Inhibition of Protein Phosphatase 1 by Nox4 Regulates Eif2Alpha-Mediated Stress Signaling. Embo J., 35, 2016
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7CBW
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![BU of 7cbw by Molmil](/molmil-images/mine/7cbw) | Blasnase-T13A with D-asn | Descriptor: | FORMIC ACID, L-asparaginase, MAGNESIUM ION | Authors: | Lu, F, Ran, T, Jiao, L, Wang, W. | Deposit date: | 2020-06-15 | Release date: | 2021-06-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.978 Å) | Cite: | Structures of l-asparaginase from Bacillus licheniformis Reveal an Essential Residue for its Substrate Stereoselectivity. J.Agric.Food Chem., 69, 2021
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4UWQ
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![BU of 4uwq by Molmil](/molmil-images/mine/4uwq) | Crystal structure of the disulfide-linked complex of the thiosulfodyrolase SoxB with the carrier-protein SoxYZ from Thermus thermophilus | Descriptor: | MANGANESE (II) ION, SOXY PROTEIN, SOXZ, ... | Authors: | Grabarczyk, D.B, Chappell, P.E, Johnson, S, Stelzl, L.S, Lea, S.M, Berks, B.C. | Deposit date: | 2014-08-14 | Release date: | 2015-12-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.28 Å) | Cite: | Structural Basis for Specificity and Promiscuity in a Carrier Protein/Enzyme System from the Sulfur Cycle Proc.Natl.Acad.Sci.USA, 112, 2015
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7C8X
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![BU of 7c8x by Molmil](/molmil-images/mine/7c8x) | Blasnase-T13A with L-asn | Descriptor: | ASPARAGINE, Asparaginase, FORMIC ACID, ... | Authors: | Lu, F, Ran, T, Jiao, L, Wang, W. | Deposit date: | 2020-06-03 | Release date: | 2021-06-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.994 Å) | Cite: | Structures of l-asparaginase from Bacillus licheniformis Reveal an Essential Residue for its Substrate Stereoselectivity. J.Agric.Food Chem., 69, 2021
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4V3U
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![BU of 4v3u by Molmil](/molmil-images/mine/4v3u) | Structure of human nNOS R354A G357D mutant heme domain in complex with N-2-(2-(1H-imidazol-1-yl)pyrimidin-4-yl)ethyl-3-(pyridin-3-yl) propan-1-amine | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, GLYCEROL, N-{2-[2-(1H-imidazol-1-yl)pyrimidin-4-yl]ethyl}-3-(pyridin-3-yl)propan-1-amine, ... | Authors: | Li, H, Poulos, T.L. | Deposit date: | 2014-10-20 | Release date: | 2014-12-24 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Novel 2,4-Disubstituted Pyrimidines as Potent, Selective, and Cell-Permeable Inhibitors of Neuronal Nitric Oxide Synthase. J.Med.Chem., 58, 2015
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4W82
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![BU of 4w82 by Molmil](/molmil-images/mine/4w82) | Enoyl-acyl carrier protein-reductase domain from human fatty acid synthase | Descriptor: | CHLORIDE ION, Fatty acid synthase, MAGNESIUM ION, ... | Authors: | Sippel, K.H, Vyas, N.K, Sankaran, B, Quiocho, F.A. | Deposit date: | 2014-08-22 | Release date: | 2014-10-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of the human Fatty Acid synthase enoyl-acyl carrier protein-reductase domain complexed with triclosan reveals allosteric protein-protein interface inhibition. J.Biol.Chem., 289, 2014
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7CB2
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4WB0
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