7P7S
| PoxtA-EQ2 antibiotic resistance ABCF bound to E. faecalis 70S ribosome, state II | Descriptor: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | Authors: | Crowe-McAuliffe, C, Wilson, D.N. | Deposit date: | 2021-07-20 | Release date: | 2022-02-23 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics. Nat Commun, 13, 2022
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7P7U
| E. faecalis 70S ribosome with P-tRNA, state IV | Descriptor: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | Authors: | Crowe-McAuliffe, C, Wilson, D.N. | Deposit date: | 2021-07-20 | Release date: | 2022-02-23 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics. Nat Commun, 13, 2022
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7P7R
| PoxtA-EQ2 antibiotic resistance ABCF bound to E. faecalis 70S ribosome, state I | Descriptor: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | Authors: | Crowe-McAuliffe, C, Wilson, D.N. | Deposit date: | 2021-07-20 | Release date: | 2022-03-23 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics. Nat Commun, 13, 2022
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7P6Z
| Mycoplasma pneumoniae 70S ribosome in untreated cells | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Xue, L, Lenz, S, Rappsilber, J, Mahamid, J. | Deposit date: | 2021-07-18 | Release date: | 2022-05-25 | Last modified: | 2022-10-19 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Visualizing translation dynamics at atomic detail inside a bacterial cell. Nature, 610, 2022
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7P48
| Staphylococcus aureus ribosome in complex with Sal(B) | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Nicholson, D, Ranson, N.A, O'Neill, A.J. | Deposit date: | 2021-07-09 | Release date: | 2022-02-02 | Last modified: | 2022-03-09 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Sal-type ABC-F proteins: intrinsic and common mediators of pleuromutilin resistance by target protection in staphylococci. Nucleic Acids Res., 50, 2022
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7P3K
| Cryo-EM structure of 70S ribosome stalled with TnaC peptide (control) | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Buschauer, R, Komar, T, Becker, T, Berninghausen, O, Cheng, J, Beckmann, R. | Deposit date: | 2021-07-08 | Release date: | 2021-10-27 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis of l-tryptophan-dependent inhibition of release factor 2 by the TnaC arrest peptide. Nucleic Acids Res., 49, 2021
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7R81
| Structure of the translating Neurospora crassa ribosome arrested by cycloheximide | Descriptor: | 18S rRNA, 26S rRNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... | Authors: | Shen, L, Su, Z, Yang, K, Wu, C, Becker, T, Bell-Pedersen, D, Zhang, J, Sachs, M.S. | Deposit date: | 2021-06-25 | Release date: | 2021-12-01 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structure of the translating Neurospora ribosome arrested by cycloheximide Proc.Natl.Acad.Sci.USA, 118, 2021
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7OYA
| Cryo-EM structure of the 1 hpf zebrafish embryo 80S ribosome | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | Authors: | Leesch, F, Lorenzo-Orts, L, Grishkovskaya, I, Kandolf, S, Belacic, K, Meinhart, A, Haselbach, D, Pauli, A. | Deposit date: | 2021-06-24 | Release date: | 2022-07-13 | Last modified: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature, 613, 2023
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7OYB
| Cryo-EM structure of the 6 hpf zebrafish embryo 80S ribosome | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | Authors: | Leesch, F, Lorenzo-Orts, L, Grishkovskaya, I, Kandolf, S, Belacic, K, Meinhart, A, Haselbach, D, Pauli, A. | Deposit date: | 2021-06-24 | Release date: | 2022-07-13 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature, 613, 2023
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7OYD
| Cryo-EM structure of a rabbit 80S ribosome with zebrafish Dap1b | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | Authors: | Leesch, F, Lorenzo-Orts, L, Grishkovskaya, I, Kandolf, S, Belacic, K, Meinhart, A, Haselbach, D, Pauli, A. | Deposit date: | 2021-06-24 | Release date: | 2022-07-20 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature, 613, 2023
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7OYC
| Cryo-EM structure of the Xenopus egg 80S ribosome | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Leesch, F, Lorenzo-Orts, L, Grishkovskaya, I, Kandolf, S, Belacic, K, Meinhart, A, Haselbach, D, Pauli, A. | Deposit date: | 2021-06-24 | Release date: | 2022-07-20 | Last modified: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature, 613, 2023
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7N8B
| Cycloheximide bound vacant 80S structure isolated from cbf5-D95A | Descriptor: | 18S RIBOSOMAL RNA, 25S, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... | Authors: | Rai, J, Zhao, Y, Li, H. | Deposit date: | 2021-06-14 | Release date: | 2022-05-11 | Last modified: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | CryoEM structures of pseudouridine-free ribosome suggest impacts of chemical modifications on ribosome conformations. Structure, 30, 2022
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7OTC
| Cryo-EM structure of an Escherichia coli 70S ribosome in complex with elongation factor G and the antibiotic Argyrin B | Descriptor: | 1,4-DIAMINOBUTANE, 16S ribosomal RNA, 23S ribosomal RNA, ... | Authors: | Wieland, M, Koller, T.O, Wilson, D.N. | Deposit date: | 2021-06-10 | Release date: | 2022-05-11 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation. Proc.Natl.Acad.Sci.USA, 119, 2022
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7OPE
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7N31
| Elongating 70S ribosome complex in a post-translocation (POST) conformation | Descriptor: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | Authors: | Rundlet, E.J, Holm, M, Schacherl, M, Natchiar, K.S, Altman, R.B, Spahn, C.M.T, Myasnikov, A.G, Blanchard, S.C. | Deposit date: | 2021-05-31 | Release date: | 2021-07-14 | Last modified: | 2021-08-11 | Method: | ELECTRON MICROSCOPY (2.69 Å) | Cite: | Structural basis of early translocation events on the ribosome. Nature, 595, 2021
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7N30
| Elongating 70S ribosome complex in a hybrid-H2* pre-translocation (PRE-H2*) conformation | Descriptor: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | Authors: | Rundlet, E.J, Holm, M, Schacherl, M, Natchiar, K.S, Altman, R.B, Spahn, C.M.T, Myasnikov, A.G, Blanchard, S.C. | Deposit date: | 2021-05-30 | Release date: | 2021-07-14 | Last modified: | 2021-08-11 | Method: | ELECTRON MICROSCOPY (2.66 Å) | Cite: | Structural basis of early translocation events on the ribosome. Nature, 595, 2021
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7N2U
| Elongating 70S ribosome complex in a hybrid-H1 pre-translocation (PRE-H1) conformation | Descriptor: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | Authors: | Rundlet, E.J, Holm, M, Schacherl, M, Natchiar, K.S, Altman, R.B, Spahn, C.M.T, Myasnikov, A.G, Blanchard, S.C. | Deposit date: | 2021-05-29 | Release date: | 2021-07-14 | Last modified: | 2021-08-11 | Method: | ELECTRON MICROSCOPY (2.53 Å) | Cite: | Structural basis of early translocation events on the ribosome. Nature, 595, 2021
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7N2V
| Elongating 70S ribosome complex in a spectinomycin-stalled intermediate state of translocation bound to EF-G in an active, GTP conformation (INT1) | Descriptor: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | Authors: | Rundlet, E.J, Holm, M, Schacherl, M, Natchiar, K.S, Altman, R.B, Spahn, C.M.T, Myasnikov, A.G, Blanchard, S.C. | Deposit date: | 2021-05-29 | Release date: | 2021-07-14 | Last modified: | 2021-08-11 | Method: | ELECTRON MICROSCOPY (2.54 Å) | Cite: | Structural basis of early translocation events on the ribosome. Nature, 595, 2021
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7N1P
| Elongating 70S ribosome complex in a classical pre-translocation (PRE-C) conformation | Descriptor: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | Authors: | Rundlet, E.J, Holm, M, Schacherl, M, Natchiar, S.K, Altman, R.B, Spahn, C.M.T, Myasnikov, A.G, Blanchard, S.C. | Deposit date: | 2021-05-28 | Release date: | 2021-07-14 | Last modified: | 2021-08-11 | Method: | ELECTRON MICROSCOPY (2.33 Å) | Cite: | Structural basis of early translocation events on the ribosome. Nature, 595, 2021
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7N2C
| Elongating 70S ribosome complex in a fusidic acid-stalled intermediate state of translocation bound to EF-G(GDP) (INT2) | Descriptor: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | Authors: | Rundlet, E.J, Holm, M, Schacherl, M, Natchiar, K.S, Altman, R.B, Spahn, C.M.T, Myasnikov, A.G, Blanchard, S.C. | Deposit date: | 2021-05-28 | Release date: | 2021-07-14 | Last modified: | 2021-08-11 | Method: | ELECTRON MICROSCOPY (2.72 Å) | Cite: | Structural basis of early translocation events on the ribosome. Nature, 595, 2021
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7OOC
| Mycoplasma pneumoniae 30S subunit of ribosomes in chloramphenicol-treated cells | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Xue, L, Lenz, S, Rappsilber, J, Mahamid, J. | Deposit date: | 2021-05-27 | Release date: | 2022-05-25 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Visualizing translation dynamics at atomic detail inside a bacterial cell. Nature, 610, 2022
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7OLD
| Thermophilic eukaryotic 80S ribosome at pe/E (TI)-POST state | Descriptor: | 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ... | Authors: | Kisonaite, M, Wild, K, Sinning, I. | Deposit date: | 2021-05-19 | Release date: | 2022-01-26 | Last modified: | 2022-02-09 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation. Nat Commun, 13, 2022
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7OLC
| Thermophilic eukaryotic 80S ribosome at idle POST state | Descriptor: | 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ... | Authors: | Kisonaite, M, Wild, K, Sinning, I. | Deposit date: | 2021-05-19 | Release date: | 2022-01-26 | Last modified: | 2022-04-06 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation. Nat Commun, 13, 2022
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7OIZ
| Cryo-EM structure of 70S ribosome stalled with TnaC peptide | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Su, T, Kudva, R, Becker, T, Berninghausen, O, Heijne, G, Cheng, J, Beckmann, R. | Deposit date: | 2021-05-13 | Release date: | 2021-09-15 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis of l-tryptophan-dependent inhibition of release factor 2 by the TnaC arrest peptide. Nucleic Acids Res., 49, 2021
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7OJ0
| Cryo-EM structure of 70S ribosome stalled with TnaC peptide and RF2 | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Su, T, Kudva, R, Becker, T, Berninghausen, O, Heijne, G, Cheng, J, Beckmann, R. | Deposit date: | 2021-05-13 | Release date: | 2021-09-15 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of l-tryptophan-dependent inhibition of release factor 2 by the TnaC arrest peptide. Nucleic Acids Res., 49, 2021
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