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5YW8
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BU of 5yw8 by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (all particles at 4.4A)
Descriptor: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Chen, L, Wu, J.X.
Deposit date:2017-11-29
Release date:2018-05-02
Last modified:2018-06-13
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YWD
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BU of 5ywd by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (focused refinement of SUR1 ABC transporter module at 4.22A)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family C member 8 isoform X2, MAGNESIUM ION
Authors:Chen, L, Wu, J.X.
Deposit date:2017-11-29
Release date:2018-05-02
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
6R84
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BU of 6r84 by Molmil
Yeast Vms1 (Q295L)-60S ribosomal subunit complex (pre-state with Arb1)
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Su, T, Izawa, T, Cheng, J, Yamashita, Y, Berninghausen, O, Inada, T, Neupert, W, Beckmann, R.
Deposit date:2019-03-31
Release date:2019-06-26
Last modified:2019-07-10
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis.
Nature, 570, 2019
6RAF
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BU of 6raf by Molmil
Heterodimeric ABC exporter TmrAB in inward-facing narrow conformation under turnover conditions
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Anti-vesicular stomatitis virus N VHH, ...
Authors:Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R.
Deposit date:2019-04-06
Release date:2019-07-31
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Conformation space of a heterodimeric ABC exporter under turnover conditions.
Nature, 571, 2019
6RAL
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BU of 6ral by Molmil
Heterodimeric ABC exporter TmrAB under turnover conditions in asymmetric unlocked return conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R.
Deposit date:2019-04-06
Release date:2019-07-31
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Conformation space of a heterodimeric ABC exporter under turnover conditions.
Nature, 571, 2019
5YW7
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BU of 5yw7 by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (focused refinement on SUR1 ABC transporter module at 4.4A)
Descriptor: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Chen, L, Wu, J.X.
Deposit date:2017-11-29
Release date:2018-05-02
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YWA
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BU of 5ywa by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (CTD class 2 at 6.1A)
Descriptor: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Chen, L, Wu, J.X.
Deposit date:2017-11-29
Release date:2018-05-02
Last modified:2018-06-13
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
6S47
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BU of 6s47 by Molmil
Saccharomyces cerevisiae 80S ribosome bound with ABCF protein New1
Descriptor: 18S rRNA (1707-MER), 28S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Kasari, V, Pochopien, A.A, Margus, T, Murina, V, Turnbull, K, Zhou, Y, Nissan, T, Graf, M, Novacek, J, Atkinson, G.C, Johansson, M.J.O, Wilson, D.N, Hauryliuk, V.
Deposit date:2019-06-26
Release date:2019-07-24
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:A role for the Saccharomyces cerevisiae ABCF protein New1 in translation termination/recycling.
Nucleic Acids Res., 47, 2019
6TEJ
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BU of 6tej by Molmil
Structure of apo IrtAB devoid SID in complex with sybody Syb_NL5
Descriptor: DECYL-BETA-D-MALTOPYRANOSIDE, Drug ABC transporter ATP-binding protein, NICKEL (II) ION, ...
Authors:Gonda, I, Arnold, F.M, Hutter, C.A.J, Weber, M.S, Seeger, M.A, Hurlimann, L.M.
Deposit date:2019-11-12
Release date:2020-04-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The ABC exporter IrtAB imports and reduces mycobacterial siderophores.
Nature, 580, 2020
6TQE
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BU of 6tqe by Molmil
The structure of ABC transporter Rv1819c without addition of substrate
Descriptor: ABC transporter ATP-binding protein/permease, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Rempel, S, Gati, C, Slotboom, D.J, Guskov, A.
Deposit date:2019-12-16
Release date:2020-04-01
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds.
Nature, 580, 2020
5ZLU
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BU of 5zlu by Molmil
Ribosome Structure bound to ABC-F protein.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Su, W.X, Kumar, V, Ero, R, Andrew, S.W.W, Jian, S, Yong-Gui, G.
Deposit date:2018-03-29
Release date:2018-08-01
Last modified:2019-12-04
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Ribosome protection by antibiotic resistance ATP-binding cassette protein.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6TMF
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BU of 6tmf by Molmil
Structure of an archaeal ABCE1-bound ribosomal post-splitting complex
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Kratzat, H, Becker, T, Tampe, R, Beckmann, R.
Deposit date:2019-12-04
Release date:2020-02-12
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Molecular analysis of the ribosome recycling factor ABCE1 bound to the 30S post-splitting complex.
Embo J., 39, 2020
6A6M
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BU of 6a6m by Molmil
Crystal structure of an outward-open nucleotide-bound state of the eukaryotic ABC multidrug transporter CmABCB1
Descriptor: ATP-binding cassette, sub-family B, member 1, ...
Authors:Kato, H, Nakatsu, T, Kodan, A.
Deposit date:2018-06-28
Release date:2019-02-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Inward- and outward-facing X-ray crystal structures of homodimeric P-glycoprotein CmABCB1.
Nat Commun, 10, 2019
8EOP
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BU of 8eop by Molmil
Cryo-EM Structure of Nanodisc reconstituted human ABCA7 EQ mutant in ATP bound closed state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Alam, A, Le, L.T.M, Thompson, J.R.
Deposit date:2022-10-04
Release date:2022-12-21
Last modified:2023-02-15
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms.
Embo J., 42, 2023
8F4B
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BU of 8f4b by Molmil
Bovine multidrug resistance protein 1 (MRP1) bound to cyclic peptide inhibitor 1 (CPI1)
Descriptor: Cyclic peptide inhibitor 1 (CPI1), Multidrug resistance-associated protein 1
Authors:Pietz, H.L, Chen, J.
Deposit date:2022-11-10
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:A macrocyclic peptide inhibitor traps MRP1 in a catalytically incompetent conformation.
Proc.Natl.Acad.Sci.USA, 120, 2023
8F5B
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BU of 8f5b by Molmil
Human ABCA4 structure in complex with AMP-PNP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Scortecci, J.F, Van Petegem, F, Molday, R.S.
Deposit date:2022-11-13
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.95 Å)
Cite:Structural and Functional Characterization of ABCA4 in its Nucleotide-Bound State
To Be Published
8FWK
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BU of 8fwk by Molmil
CryoEM structure of Human ABCB6 Transporter
Descriptor: ATP-binding cassette sub-family B member 6
Authors:Shaik, M.M, Myasnikov, A.
Deposit date:2023-01-22
Release date:2023-02-08
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:CryoEM structure of Human ABCB6 Transporter
To Be Published
8FEF
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BU of 8fef by Molmil
Structure of Mce1 transporter from Mycobacterium smegmatis (Map0)
Descriptor: ABC transporter, ATP-binding protein,Green fluorescent protein chimera, ABC-transporter integral membrane protein, ...
Authors:Chen, J, Bhabha, G, Ekiert, D.C.
Deposit date:2022-12-06
Release date:2023-02-22
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (2.71 Å)
Cite:Structure of an endogenous mycobacterial MCE lipid transporter.
Nature, 620, 2023
8FED
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BU of 8fed by Molmil
Structure of Mce1-LucB complex from Mycobacterium smegmatis (Map1)
Descriptor: ABC transporter, ATP-binding protein,Green fluorescent protein chimera, ABC-transporter integral membrane protein, ...
Authors:Chen, J, Bhabha, G, Ekiert, D.C.
Deposit date:2022-12-06
Release date:2023-02-22
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Structure of an endogenous mycobacterial MCE lipid transporter.
Nature, 620, 2023
8FEE
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BU of 8fee by Molmil
Structure of Mce1 transporter from Mycobacterium smegmatis in the absence of LucB (Map2)
Descriptor: ABC transporter, ATP-binding protein,Green fluorescent protein chimera, ABC-transporter integral membrane protein, ...
Authors:Chen, J, Bhabha, G, Ekiert, D.C.
Deposit date:2022-12-06
Release date:2023-02-22
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure of an endogenous mycobacterial MCE lipid transporter.
Nature, 620, 2023
8FMV
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BU of 8fmv by Molmil
Heterodimeric ABC transporter BmrCD in the inward-facing conformation bound to substrate and ATP: BmrCD_IF-2HT/ATP
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Tang, Q, Mchaourab, H.
Deposit date:2022-12-24
Release date:2023-11-15
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter.
Nat Commun, 14, 2023
8FHK
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BU of 8fhk by Molmil
Heterodimeric ABC transporter BmrCD in the occluded conformation bound to ATP: BmrCD_OC-ATP
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Tang, Q, Mchaourab, H.
Deposit date:2022-12-14
Release date:2023-11-15
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter.
Nat Commun, 14, 2023
8FPF
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BU of 8fpf by Molmil
Heterodimeric ABC transporter BmrCD in the inward-facing conformation bound to ATP: BmrCD_IF-ATP
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH, ...
Authors:Qingyu, T, Hassane, M.
Deposit date:2023-01-04
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter
Nat Commun, 14, 2023
8FRP
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BU of 8frp by Molmil
Acinetobacter baylyi LptB2FGC
Descriptor: LPS export ABC transporter permease LptG, Lipopolysaccharide export system ATP-binding protein LptB, Lipopolysaccharide export system permease protein LptF, ...
Authors:Pahil, K.S, Gilman, M.S.A, Kruse, A.C, Kahne, D.
Deposit date:2023-01-07
Release date:2024-01-03
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:A new antibiotic traps lipopolysaccharide in its intermembrane transporter.
Nature, 625, 2024
8FRM
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BU of 8frm by Molmil
Acinetobacter baylyi LptB2FG bound to lipopolysaccharide.
Descriptor: (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-5-[(2~{S},3~{S},4~{R},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{R},5~{S},6~{R})-6-[(1~{S})-2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-1-oxidanyl-ethyl]-3,4-bis(oxidanyl)-5-phosphonooxy-oxan-2-yl]oxy-3-oxidanyl-5-phosphonooxy-oxan-2-yl]oxy-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, LPS export ABC transporter permease LptG, Lipopolysaccharide export system ATP-binding protein LptB, ...
Authors:Pahil, K.S, Gilman, M.S.A, Kruse, A.C, Kahne, D.
Deposit date:2023-01-07
Release date:2024-01-03
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:A new antibiotic traps lipopolysaccharide in its intermembrane transporter.
Nature, 625, 2024

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