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4YE9	The crystal structure of the G45V mutant of human GlnRS Descriptor: Glutamine--tRNA ligase Authors: Ognjenovic, J, Wu, J, Ling, J, Simonovic, M. Deposit date: 2015-02-23 Release date: 2016-02-17 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.7 Å) Cite: The crystal structure of human GlnRS provides basis for the development of neurological disorders. Nucleic Acids Res., 44, 2016
6BRL	Crystal structure of a glutamate tRNA ligase from Elizabethkingia meningosepticum CCUG26117 in complex with its amino acid Descriptor: 1,2-ETHANEDIOL, GLUTAMIC ACID, Glutamate tRNA ligase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2017-11-30 Release date: 2018-01-17 Last modified: 2024-07-03 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structures of glutamyl-tRNA synthetase from Elizabethkingia anopheles and E. meningosepticum. Acta Crystallogr.,Sect.F, 78, 2022
4YE8	The crystal structure of the Y57H mutant of human GlnRS Descriptor: Glutamine--tRNA ligase Authors: Ognjenovic, J, Wu, J, Ling, J, Simonovic, M. Deposit date: 2015-02-23 Release date: 2016-02-17 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.3 Å) Cite: The crystal structure of human GlnRS provides basis for the development of neurological disorders. Nucleic Acids Res., 44, 2016
2O5R	Crystal structure of Glutamyl-tRNA synthetase 1 (EC 6.1.1.17) (Glutamate-tRNA ligase 1) (GluRS 1) (TM1351) from Thermotoga maritima at 2.5 A resolution Descriptor: CHLORIDE ION, GLYCEROL, Glutamyl-tRNA synthetase 1 Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2006-12-06 Release date: 2006-12-19 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.34 Å) Cite: Crystal structure of Glutamyl-tRNA synthetase 1 (EC 6.1.1.17) (Glutamate-tRNA ligase 1) (GluRS 1) (TM1351) from Thermotoga maritima at 2.5 A resolution To be published
2RE8	Glutaminyl-tRNA synthetase mutant C229R with bound analog 5'-O-[N-(L-GLUTAMYL)-SULFAMOYL]ADENOSINE Descriptor: Glutamine tRNA, Glutaminyl-tRNA synthetase, O5'-(L-GLUTAMYL-SULFAMOYL)-ADENOSINE, ... Authors: Bullock, T.L, Perona, J.J. Deposit date: 2007-09-25 Release date: 2008-01-15 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.6 Å) Cite: A rationally engineered misacylating aminoacyl-tRNA synthetase. Proc.Natl.Acad.Sci.Usa, 105, 2008
2RD2	Glutaminyl-tRNA synthetase mutant C229R with bound analog 5'-O-[N-(L-GLUTAMINYL)-SULFAMOYL]ADENOSINE Descriptor: 5'-O-[N-(L-GLUTAMINYL)-SULFAMOYL]ADENOSINE, Glutamine tRNA, Glutaminyl-tRNA synthetase, ... Authors: Bullock, T.L, Perona, J.J. Deposit date: 2007-09-20 Release date: 2008-01-15 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.6 Å) Cite: A rationally engineered misacylating aminoacyl-tRNA synthetase. Proc.Natl.Acad.Sci.Usa, 105, 2008
3AFH	Crystal structure of Thermotoga maritima nondiscriminating glutamyl-tRNA synthetase in complex with a glutamyl-AMP analog Descriptor: Glutamyl-tRNA synthetase 2, O5'-(L-GLUTAMYL-SULFAMOYL)-ADENOSINE Authors: Ito, T, Yokoyama, S. Deposit date: 2010-03-01 Release date: 2010-06-30 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure of nondiscriminating glutamyl-tRNA synthetase from Thermotoga maritima Acta Crystallogr.,Sect.D, 66, 2010
3AII	Archaeal non-discriminating glutamyl-tRNA synthetase from Methanothermobacter thermautotrophicus Descriptor: 1,2-ETHANEDIOL, ACETIC ACID, CALCIUM ION, ... Authors: Nureki, O, Ishitani, R. Deposit date: 2010-05-14 Release date: 2010-08-04 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Structure of an archaeal non-discriminating glutamyl-tRNA synthetase: a missing link in the evolution of Gln-tRNAGln formation Nucleic Acids Res., 2010
3AL0	Crystal structure of the glutamine transamidosome from Thermotoga maritima in the glutamylation state. Descriptor: Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Glutamyl-tRNA(Gln) amidotransferase subunit A, Glutamyl-tRNA(Gln) amidotransferase subunit C,Linker,Glutamate--tRNA ligase 2, ... Authors: Ito, T, Yokoyama, S. Deposit date: 2010-07-19 Release date: 2010-09-29 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (3.368 Å) Cite: Two enzymes bound to one transfer RNA assume alternative conformations for consecutive reactions. Nature, 467, 2010
3AKZ	Crystal structure of Thermotoga maritima nondiscriminating glutamyl-tRNA synthetase in complex with tRNAGln and a glutamyl-AMP analog Descriptor: Glutamyl-tRNA synthetase 2, O5'-(L-GLUTAMYL-SULFAMOYL)-ADENOSINE, tRNAGln Authors: Ito, T, Yokoyama, S. Deposit date: 2010-07-19 Release date: 2010-09-29 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Two enzymes bound to one transfer RNA assume alternative conformations for consecutive reactions. Nature, 467, 2010
2CV1	Glutamyl-tRNA synthetase from Thermus thermophilus in complex with tRNA(Glu), ATP, and an analog of L-glutamate: a quaternary complex Descriptor: (4S)-4-AMINO-5-HYDROXYPENTANOIC ACID, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2005-05-31 Release date: 2006-09-05 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.41 Å) Cite: Glutamyl-tRNA synthetase from Thermus thermophilus in complex with tRNA(Glu), ATP, and an analog of L-glutamate: a quaternary complex To be Published
2CV0	Glutamyl-tRNA synthetase from Thermus thermophilus in complex with tRNA(Glu) and L-glutamate Descriptor: GLUTAMIC ACID, MAGNESIUM ION, glutamyl-tRNA synthetase, ... Authors: Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2005-05-31 Release date: 2006-09-05 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural bases of transfer RNA-dependent amino acid recognition and activation by glutamyl-tRNA synthetase Structure, 14, 2006
2CUZ	Glutamyl-tRNA synthetase from Thermus thermophilus in complex with L-glutamate Descriptor: GLUTAMIC ACID, Glutamyl-tRNA synthetase Authors: Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2005-05-31 Release date: 2006-09-05 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Structural bases of transfer RNA-dependent amino acid recognition and activation by glutamyl-tRNA synthetase Structure, 14, 2006
2CV2	Glutamyl-tRNA synthetase from Thermus thermophilus in complex with tRNA(Glu) and an enzyme inhibitor, Glu-AMS Descriptor: CHLORIDE ION, MAGNESIUM ION, O5'-(L-GLUTAMYL-SULFAMOYL)-ADENOSINE, ... Authors: Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2005-05-31 Release date: 2006-09-05 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.69 Å) Cite: Structural bases of transfer RNA-dependent amino acid recognition and activation by glutamyl-tRNA synthetase Structure, 14, 2006
4G6Z	Crystal structure of a glutamyl-tRNA synthetase GluRS from Burkholderia thailandensis bound to L-glutamate Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, GLUTAMIC ACID, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-07-19 Release date: 2012-08-01 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms. Sci Rep, 7, 2017
2DXI	2.2 A crystal structure of glutamyl-tRNA synthetase from Thermus thermophilus complexed with tRNA(Glu), ATP, and L-glutamol Descriptor: (4S)-4-AMINO-5-HYDROXYPENTANOIC ACID, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2006-08-28 Release date: 2006-10-31 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural bases of transfer RNA-dependent amino acid recognition and activation by glutamyl-tRNA synthetase Structure, 14, 2006
4GRI	Crystal structure of a glutamyl-tRNA synthetase GluRS from Borrelia burgdorferi bound to glutamic acid and zinc Descriptor: CHLORIDE ION, GLUTAMIC ACID, Glutamate--tRNA ligase, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-08-24 Release date: 2012-09-05 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms. Sci Rep, 7, 2017
2CFO	Non-Discriminating Glutamyl-tRNA Synthetase from Thermosynechococcus elongatus in Complex with Glu Descriptor: GLUTAMIC ACID, GLUTAMYL-TRNA SYNTHETASE Authors: Schulze, J.O, Nickel, D, Schubert, W.-D, Jahn, D, Heinz, D.W. Deposit date: 2006-02-22 Release date: 2006-08-16 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Crystal Structure of a Non-Discriminating Glutamyl- tRNA Synthetase. J.Mol.Biol., 361, 2006
4H3S	The Structure of Glutaminyl-tRNA Synthetase from Saccharomyces Cerevisiae Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ACETATE ION, BROMIDE ION, ... Authors: Snell, E.H, Grant, T.D. Deposit date: 2012-09-14 Release date: 2013-04-24 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.15 Å) Cite: The Structure of Yeast Glutaminyl-tRNA Synthetase and Modeling of Its Interaction with tRNA. J.Mol.Biol., 425, 2013
4JXX	Crystal structure of E coli E. coli glutaminyl-tRNA synthetase bound to tRNA(Gln)(CUG) and ATP from novel cryostabilization conditions Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Glutamine--tRNA ligase, RNA (71-MER), ... Authors: Perona, J.J, Rodriguez-Hernandez, A. Deposit date: 2013-03-28 Release date: 2013-05-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural and Mechanistic Basis for Enhanced Translational Efficiency by 2-Thiouridine at the tRNA Anticodon Wobble Position. J.Mol.Biol., 425, 2013
4JXZ	Structure of E. coli glutaminyl-tRNA synthetase bound to ATP and a tRNA(Gln) acceptor containing a UUG anticodon Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Glutamine--tRNA ligase, RNA (71-MER), ... Authors: Perona, J.J, Rodriguez-Hernandez, A. Deposit date: 2013-03-28 Release date: 2013-05-01 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural and Mechanistic Basis for Enhanced Translational Efficiency by 2-Thiouridine at the tRNA Anticodon Wobble Position. J.Mol.Biol., 425, 2013
4JYZ	Crystal structure of E. coli glutaminyl-tRNA synthetase bound to ATP and native tRNA(Gln) containing the cmnm5s2U34 anticodon wobble base Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Glutamine--tRNA ligase, RNA (72-MER), ... Authors: Perona, J.J, Rodriguez-Hernandez, A. Deposit date: 2013-04-01 Release date: 2013-05-29 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural and Mechanistic Basis for Enhanced Translational Efficiency by 2-Thiouridine at the tRNA Anticodon Wobble Position. J.Mol.Biol., 425, 2013
7WRS	Crystal structure of the chicken isoleucyl-tRNA synthetase 1 (IARS1) UNE-I complexed with glutamyl-tRNA synthetase 1 (EARS1) Descriptor: Glutamyl-tRNA synthetase, Isoleucyl-tRNA synthetase Authors: Chung, S, Cho, Y. Deposit date: 2022-01-27 Release date: 2022-11-23 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Regulation of BRCA1 stability through the tandem UBX domains of isoleucyl-tRNA synthetase 1. Nat Commun, 13, 2022
7WRU	Crystal structure of the apo chicken glutamyl-tRNA synthetase 1 (EARS1) Descriptor: Glutamyl-tRNA synthetase, MERCURY (II) ION Authors: Chung, S, Cho, Y. Deposit date: 2022-01-27 Release date: 2022-11-23 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Regulation of BRCA1 stability through the tandem UBX domains of isoleucyl-tRNA synthetase 1. Nat Commun, 13, 2022
7WAK	Glutamyl-tRNA synthetase from Plasmodium falciparum (PfERS) in complex with ADP Descriptor: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Glutamyl-tRNA synthetase, ... Authors: Sharma, V, Manickam, Y, Babbar, P, Sharma, A. Deposit date: 2021-12-14 Release date: 2022-12-21 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.782 Å) Cite: Structural characterization of glutamyl-tRNA synthetase (GluRS) from Plasmodium falciparum. Mol.Biochem.Parasitol., 253, 2022

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