PDB: 13252 resultsInfo pagesStatus searchChemie searchBIRD

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3FTM	Class II ligase ribozyme product-template duplex, structure 1 Descriptor: 5'-R(*CP*CP*AP*GP*UP*CP*GP*GP*AP*AP*CP*A)-3', 5'-R(*GP*UP*GP*UP*GP*AP*GP*GP*CP*UP*G)-3', MAGNESIUM ION, ... Authors: Pitt, J.N, Ferre-D'Amare, A.R. Deposit date: 2009-01-13 Release date: 2009-02-24 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structure-guided engineering of the regioselectivity of RNA ligase ribozymes. J.Am.Chem.Soc., 131, 2009
3K75	X-ray crystal structure of reduced XRCC1 bound to DNA pol beta catalytic domain Descriptor: DNA polymerase beta, DNA repair protein XRCC1 Authors: Cuneo, M.J, London, R.E. Deposit date: 2009-10-12 Release date: 2010-04-28 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity. Proc.Natl.Acad.Sci.USA, 107, 2010
3LQC	X-ray crystal structure of oxidized XRCC1 bound to DNA pol beta Palm thumb domain Descriptor: CARBONATE ION, DNA polymerase beta, DNA repair protein XRCC1, ... Authors: Cuneo, M.J, Krahn, J.M, London, R.E. Deposit date: 2010-02-09 Release date: 2010-04-28 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.349 Å) Cite: Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity. Proc.Natl.Acad.Sci.USA, 107, 2010
3B0Y	K263D mutant of PolX from Thermus thermophilus HB8 complexed with Ca-dGTP Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, CHLORIDE ION, ... Authors: Nakane, S, Nakagawa, N, Masui, R, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2011-06-17 Release date: 2012-05-02 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.45 Å) Cite: The structural basis of the kinetic mechanism of a gap-filling X-family DNA polymerase that binds Mg(2+)-dNTP before binding to DNA. J.Mol.Biol., 417, 2012
3B0X	K263A mutant of PolX from Thermus thermophilus HB8 complexed with Ca-dGTP Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, CHLORIDE ION, ... Authors: Nakane, S, Nakagawa, N, Masui, R, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2011-06-17 Release date: 2012-05-02 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.36 Å) Cite: The structural basis of the kinetic mechanism of a gap-filling X-family DNA polymerase that binds Mg(2+)-dNTP before binding to DNA. J.Mol.Biol., 417, 2012
4R5W	Human artd1 (parp1) - catalytic domain in complex with inhibitor xav939 Descriptor: 2-[4-(trifluoromethyl)phenyl]-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-4-ol, Poly [ADP-ribose] polymerase 1, SULFATE ION Authors: Karlberg, T, Thorsell, A.G, Schuler, H. Deposit date: 2014-08-22 Release date: 2015-09-02 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.84 Å) Cite: Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors. J.Med.Chem., 60, 2017
5QRI	PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z2856434826 Descriptor: CADMIUM ION, T-box transcription factor T, [4-(propan-2-yl)piperazin-1-yl](thiophen-2-yl)methanone Authors: Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. Deposit date: 2019-05-25 Release date: 2019-07-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.83 Å) Cite: PanDDA analysis group deposition To Be Published
5QRG	PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z275151340 Descriptor: 4-chloro-N-cyclopentyl-1-methyl-1H-pyrazole-3-carboxamide, CADMIUM ION, T-box transcription factor T Authors: Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. Deposit date: 2019-05-25 Release date: 2019-07-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.95 Å) Cite: PanDDA analysis group deposition To Be Published
5QRF	PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z373768900 Descriptor: CADMIUM ION, N-(1-ethyl-1H-pyrazol-4-yl)cyclobutanecarboxamide, T-box transcription factor T Authors: Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. Deposit date: 2019-05-25 Release date: 2019-07-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.03 Å) Cite: PanDDA analysis group deposition To Be Published
5QRN	PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z54226006 Descriptor: (2,6-difluorophenyl)(pyrrolidin-1-yl)methanone, CADMIUM ION, T-box transcription factor T Authors: Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. Deposit date: 2019-05-25 Release date: 2019-07-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.62 Å) Cite: PanDDA analysis group deposition To Be Published
5QRL	PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z437516460 Descriptor: CADMIUM ION, N-[(6-methylpyridin-3-yl)methyl]cyclobutanecarboxamide, T-box transcription factor T Authors: Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. Deposit date: 2019-05-25 Release date: 2019-07-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.76 Å) Cite: PanDDA analysis group deposition To Be Published
5QRS	PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z1891773393 Descriptor: CADMIUM ION, N-{4-[(1S)-1-aminoethyl]phenyl}cyclopropanecarboxamide, T-box transcription factor T Authors: Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. Deposit date: 2019-05-25 Release date: 2019-07-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.06 Å) Cite: PanDDA analysis group deposition To Be Published
5QRW	PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z1509882419 Descriptor: 1-(propan-2-yl)-1H-imidazole-4-sulfonamide, CADMIUM ION, T-box transcription factor T Authors: Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. Deposit date: 2019-05-25 Release date: 2019-07-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.74 Å) Cite: PanDDA analysis group deposition To Be Published
5QS1	PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z1954800564 Descriptor: 5-methoxy-1,3-benzothiazol-2-amine, CADMIUM ION, T-box transcription factor T Authors: Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. Deposit date: 2019-05-25 Release date: 2019-07-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.66 Å) Cite: PanDDA analysis group deposition To Be Published
5QRT	PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z31735562 Descriptor: CADMIUM ION, T-box transcription factor T, ~{N}-(3-acetamidophenyl)-2-methoxy-ethanamide Authors: Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. Deposit date: 2019-05-25 Release date: 2019-07-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.77 Å) Cite: PanDDA analysis group deposition To Be Published
5QRY	PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z2856434890 Descriptor: 4-methyl-N-phenylpiperazine-1-carboxamide, CADMIUM ION, T-box transcription factor T Authors: Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. Deposit date: 2019-05-25 Release date: 2019-07-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.58 Å) Cite: PanDDA analysis group deposition To Be Published
5QS5	PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z32400357 Descriptor: 1-(3-methylbenzene-1-carbonyl)piperidine-4-carboxamide, CADMIUM ION, T-box transcription factor T Authors: Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. Deposit date: 2019-05-25 Release date: 2019-07-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.81 Å) Cite: PanDDA analysis group deposition To Be Published
5QS2	PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z291279160 Descriptor: 1-[2-(trifluoromethyloxy)phenyl]thiourea, CADMIUM ION, T-box transcription factor T Authors: Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. Deposit date: 2019-05-25 Release date: 2019-07-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.68 Å) Cite: PanDDA analysis group deposition To Be Published
5QRJ	PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z416341642 Descriptor: (2R)-N,2-dimethyl-N-(propan-2-yl)morpholine-4-sulfonamide, CADMIUM ION, T-box transcription factor T Authors: Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. Deposit date: 2019-05-25 Release date: 2019-07-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.81 Å) Cite: PanDDA analysis group deposition To Be Published
5QRO	PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z1506050651 Descriptor: (1S)-N,2,2-trimethyl-N-(pyridin-3-yl)cyclopropane-1-carboxamide, CADMIUM ION, T-box transcription factor T Authors: Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. Deposit date: 2019-05-25 Release date: 2019-07-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.61 Å) Cite: PanDDA analysis group deposition To Be Published
5QRR	PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z31720228 Descriptor: 2-(2-methyl-1,3-thiazol-4-yl)-1-(morpholin-4-yl)ethan-1-one, CADMIUM ION, T-box transcription factor T Authors: Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. Deposit date: 2019-05-25 Release date: 2019-07-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.69 Å) Cite: PanDDA analysis group deposition To Be Published
5QRX	PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z364328788 Descriptor: 3-(acetylamino)-4-fluorobenzoic acid, CADMIUM ION, T-box transcription factor T Authors: Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. Deposit date: 2019-05-25 Release date: 2019-07-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.87 Å) Cite: PanDDA analysis group deposition To Be Published
5QS3	PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z198195770 Descriptor: CADMIUM ION, N-[3-(carbamoylamino)phenyl]acetamide, T-box transcription factor T Authors: Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. Deposit date: 2019-05-25 Release date: 2019-07-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.71 Å) Cite: PanDDA analysis group deposition To Be Published
5QRP	PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z2442270563 Descriptor: 4-[(3-cyclopropyl-1,2,4-oxadiazol-5-yl)methyl]piperidine, CADMIUM ION, T-box transcription factor T Authors: Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. Deposit date: 2019-05-25 Release date: 2019-07-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.67 Å) Cite: PanDDA analysis group deposition To Be Published
5QRU	PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z235341991 Descriptor: CADMIUM ION, N-(2-methoxy-5-methylphenyl)glycinamide, T-box transcription factor T Authors: Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. Deposit date: 2019-05-25 Release date: 2019-07-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.76 Å) Cite: PanDDA analysis group deposition To Be Published

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