PDB: 72308 resultsInfo pagesStatus searchChemie searchBIRD

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2G8U	B. halodurans RNase H catalytic domain D132N mutant in complex with Mg2+ and RNA/DNA hybrid (non-P nick at the active site) Descriptor: 5'-D(*AP*TP*GP*TP*CP*G)-3', 5'-R(*UP*CP*GP*AP*CP*A)-3', MAGNESIUM ION, ... Authors: Nowotny, M, Yang, W. Deposit date: 2006-03-03 Release date: 2006-04-25 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release. Embo J., 25, 2006
4OZ0	Crystal structure of human CAPERalpha U2AF homology motif (apo-state) Descriptor: CHLORIDE ION, RNA-binding protein 39 Authors: Loerch, S, Kielkopf, C.L. Deposit date: 2014-02-13 Release date: 2014-05-14 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Cancer-relevant splicing factor CAPER alpha engages the essential splicing factor SF3b155 in a specific ternary complex. J.Biol.Chem., 289, 2014
2G92	Crystal Structure Analysis of the RNA Dodecamer CGC-(NF2)-AAUUAGCG, with an Incorporated 2,4-Difluorotoluyl Residue (NF2) Descriptor: 5'-R(*CP*GP*CP*(NF2)P*AP*AP*UP*UP*AP*GP*CP*G)-3' Authors: Egli, M, Li, F. Deposit date: 2006-03-04 Release date: 2006-04-18 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.61 Å) Cite: Gene silencing activity of siRNAs with a ribo-difluorotoluyl nucleotide. Acs Chem.Biol., 1, 2006
6KLB	Structure of LbCas12a-crRNA complex bound to AcrVA4 (form B complex) Descriptor: AcrVA4, LbCas12a, MAGNESIUM ION, ... Authors: Peng, R, Li, Z, Xu, Y, He, S, Peng, Q, Shi, Y, Gao, G.F. Deposit date: 2019-07-30 Release date: 2019-09-11 Last modified: 2019-11-06 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Structural insight into multistage inhibition of CRISPR-Cas12a by AcrVA4. Proc.Natl.Acad.Sci.USA, 116, 2019
7LVK	Cfr-modified 50S subunit from Escherichia coli Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... Authors: Stojkovic, V, Myasnikov, A.G, Frost, A, Fujimori, D.G. Deposit date: 2021-02-25 Release date: 2021-12-15 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (2.2 Å) Cite: Investigating antibiotic resistance of a ribosomal-RNA methylating enzyme through directed evolution To Be Published
6DCB	Structure of methylphosphate capping enzyme methyltransferase domain in complex with 5' end of 7SK RNA Descriptor: 7SK snRNA methylphosphate capping enzyme, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... Authors: Yang, Y, Eichhorn, C, Cascio, D, Feigon, J. Deposit date: 2018-05-04 Release date: 2018-12-19 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.998 Å) Cite: Structural basis of 7SK RNA 5'-gamma-phosphate methylation and retention by MePCE. Nat. Chem. Biol., 15, 2019
6DCC	Structure of methylphosphate capping enzyme methyltransferase domain in complex with 5' end of 7SK RNA Descriptor: 7SK snRNA methylphosphate capping enzyme, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... Authors: Yang, Y, Eichhorn, C, Cascio, D, Feigon, J. Deposit date: 2018-05-04 Release date: 2018-12-19 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural basis of 7SK RNA 5'-gamma-phosphate methylation and retention by MePCE. Nat. Chem. Biol., 15, 2019
8EEX	Cas7-11 in complex with Csx29 Descriptor: Cas7-11, Csx29, ZINC ION, ... Authors: Demircioglu, F.E, Wilkinson, M.E, Strecker, J, Li, D, Faure, G, Macrae, R.K, Zhang, F. Deposit date: 2022-09-07 Release date: 2022-11-16 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.95 Å) Cite: RNA-activated protein cleavage with a CRISPR-associated endopeptidase. Science, 378, 2022
2G32	Crystal structure of an RNA racemate Descriptor: CALCIUM ION, GLYCEROL, RNA (5'-R(*(0C)P*(0C)P*(0G)P*(0C)P*(0C)P*(0U)P*(0G)P*(0G))-3'), ... Authors: Rypniewski, W, Vallazza, M, Perbandt, M, Klussmann, S, Betzel, C, Erdmann, V.A. Deposit date: 2006-02-17 Release date: 2006-05-30 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.3 Å) Cite: The first crystal structure of an RNA racemate. Acta Crystallogr.,Sect.D, 62, 2006
4V5K	Structure of cytotoxic domain of colicin E3 bound to the 70S ribosome Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... Authors: Ng, C.L, Lang, K, Meenan, N.A.G, Sharma, A, Kelley, A.C, Kleanthous, C, Ramakrishnan, V. Deposit date: 2010-05-29 Release date: 2014-07-09 Last modified: 2019-07-31 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structural Basis for 16S Ribosomal RNA Cleavage by the Cytotoxic Domain of Colicin E3. Nat.Struct.Mol.Biol., 17, 2010
8EMB	X-ray crystal structure of Thermosynechococcus elongatus Si3 domain of RNA polymerase RpoC2 subunit Descriptor: DNA-directed RNA polymerase subunit beta' Authors: Murakami, K.S, Imashimizu, M, Qayyum, M.Z, Vishwakarma, R.K, Yuzenkova, Y. Deposit date: 2022-09-27 Release date: 2022-11-09 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.06 Å) Cite: Structure and function of the Si3 insertion integrated into the trigger loop/helix of cyanobacterial RNA polymerase. Proc.Natl.Acad.Sci.USA, 121, 2024
5E02	Structure of RNA Helicase FRH a Critical Component of the Neurospora Crassa Circadian Clock Descriptor: ADENOSINE-5'-DIPHOSPHATE, FRQ-interacting RNA helicase, RNA (5'-R(*AP*AP*AP*A)-3') Authors: Conrad, K.S, Crane, B.C. Deposit date: 2015-09-28 Release date: 2016-07-06 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.8 Å) Cite: Structure of the frequency-interacting RNA helicase: a protein interaction hub for the circadian clock. Embo J., 35, 2016
6Z6J	Cryo-EM structure of yeast Lso2 bound to 80S ribosomes under native condition Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... Authors: Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R. Deposit date: 2020-05-28 Release date: 2020-07-29 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes. Plos Biol., 18, 2020
6Z6K	Cryo-EM structure of yeast reconstituted Lso2 bound to 80S ribosomes Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... Authors: Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R. Deposit date: 2020-05-28 Release date: 2020-07-29 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes. Plos Biol., 18, 2020
2G1G	Solution structure of the anticodon loop of S. Pombe tRNAi including the naturally occurring N6-threonyl adenine Descriptor: 5'-R(*AP*CP*GP*GP*GP*CP*UP*CP*AP*UP*(T6A)P*AP*CP*CP*CP*GP*U)-3' Authors: Lescrinier, E. Deposit date: 2006-02-14 Release date: 2006-06-20 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: The naturally occurring N6-threonyl adenine in anticodon loop of Schizosaccharomyces pombe tRNAi causes formation of a unique U-turn motif Nucleic Acids Res., 34, 2006
6DTI	Structure of the Thermus thermophilus 30S ribosomal subunit complexed with an unmodifed anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 2 (TRNAARG2) bound to an mRNA with an CGU-codon in the A-site and paromomycin Descriptor: 16s rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... Authors: Cantara, W.A, DeMirci, H, Agris, P.F. Deposit date: 2018-06-16 Release date: 2019-04-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.54 Å) Cite: A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine. J.Mol.Biol., 432, 2020
8EA4	V-K CAST Transpososome from Scytonema hofmanni, minor configuration Descriptor: 30S ribosomal protein S15, ADENOSINE-5'-TRIPHOSPHATE, Cas12k, ... Authors: Rizo, A.R, Park, J.-U, Tsai, A.W, Kellogg, E.K. Deposit date: 2022-08-27 Release date: 2022-11-30 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structures of the holo CRISPR RNA-guided transposon integration complex. Nature, 613, 2023
8EA3	V-K CAST Transpososome from Scytonema hofmanni, major configuration Descriptor: 30S ribosomal protein S15, ADENOSINE-5'-TRIPHOSPHATE, Cas12k, ... Authors: Rizo, A.N, Park, J.-U, Tsai, A.W, Kellogg, E.H. Deposit date: 2022-08-27 Release date: 2022-11-30 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structures of the holo CRISPR RNA-guided transposon integration complex. Nature, 613, 2023
8S9T	CRISPR-Cas type III-D effector complex Descriptor: CRISPR RNA, Cas10, Cas7-2x, ... Authors: Schwartz, E.A, Taylor, D.W. Deposit date: 2023-03-30 Release date: 2024-04-24 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.52 Å) Cite: RNA targeting and cleavage by the type III-Dv CRISPR effector complex. Nat Commun, 15, 2024
4V7B	Visualization of two tRNAs trapped in transit during EF-G-mediated translocation Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... Authors: Ramrath, D.J.F, Lancaster, L, Sprink, T, Mielke, T, Loerke, J, Noller, H.F, Spahn, C.M.T. Deposit date: 2013-10-27 Release date: 2014-07-09 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (6.8 Å) Cite: Visualization of two transfer RNAs trapped in transit during elongation factor G-mediated translocation. Proc.Natl.Acad.Sci.USA, 110, 2013
6DB9	Structural basis for promiscuous binding and activation of fluorogenic dyes by DIR2s RNA aptamer Descriptor: Fab-Heavy-Chain, Fab-Light-Chain, MAGNESIUM ION, ... Authors: Shao, Y, Shelke, S.A, Laski, A, Piccirilli, J.A. Deposit date: 2018-05-02 Release date: 2018-11-14 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.025 Å) Cite: Structural basis for activation of fluorogenic dyes by an RNA aptamer lacking a G-quadruplex motif. Nat Commun, 9, 2018
6DB8	Structural basis for promiscuous binding and activation of fluorogenic dyes by DIR2s RNA aptamer Descriptor: 2-[(Z)-(3-methyl-1,3-benzoxazol-2(3H)-ylidene)methyl]-3-(3-sulfopropyl)-1,3-benzothiazol-3-ium, Fab-Heavy chain, Fab-Light chain, ... Authors: Shao, Y, Shelke, S.A, Laski, A, Piccirilli, J.A. Deposit date: 2018-05-02 Release date: 2018-11-14 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.86541343 Å) Cite: Structural basis for activation of fluorogenic dyes by an RNA aptamer lacking a G-quadruplex motif. Nat Commun, 9, 2018
4V8E	Crystal structure analysis of ribosomal decoding (near-cognate tRNA-tyr complex). Descriptor: 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... Authors: Jenner, L, Demeshkina, N, Yusupov, M, Yusupova, G. Deposit date: 2011-12-07 Release date: 2014-07-09 Last modified: 2019-07-03 Method: X-RAY DIFFRACTION (3.3 Å) Cite: A new understanding of the decoding principle on the ribosome. Nature, 484, 2012
4V8D	Structure analysis of ribosomal decoding (cognate tRNA-tyr complex). Descriptor: 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... Authors: Jenner, L, Demeshkina, N, Yusupov, M, Yusupova, G. Deposit date: 2011-12-07 Release date: 2014-07-09 Last modified: 2019-07-03 Method: X-RAY DIFFRACTION (3 Å) Cite: A new understanding of the decoding principle on the ribosome. Nature, 484, 2012
4V8B	Crystal structure analysis of ribosomal decoding (near-cognate tRNA-leu complex). Descriptor: 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... Authors: Jenner, L, Demeshkina, N, Yusupov, M, Yusupova, G. Deposit date: 2011-12-06 Release date: 2014-07-09 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (3 Å) Cite: A new understanding of the decoding principle on the ribosome. Nature, 484, 2012

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