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7ZEB
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BU of 7zeb by Molmil
Complex I from Ovis aries at pH9, Closed state
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ADENOSINE MONOPHOSPHATE, ...
Authors:Sazanov, L, Petrova, O.
Deposit date:2022-03-30
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
7ZD6
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BU of 7zd6 by Molmil
Complex I from Ovis aries, at pH7.4, Open state
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
Authors:Sazanov, L, Petrova, O.
Deposit date:2022-03-29
Release date:2022-09-21
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
9H7X
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BU of 9h7x by Molmil
SmsC2 dimer from M. jannaschii
Descriptor: AMP PHOSPHORAMIDATE, Uncharacterized ABC transporter ATP-binding protein MJ0035, ZINC ION
Authors:Mechaly, A.E, Dussouchaud, M, Haouz, A, Betton, J.M, Barras, F.
Deposit date:2024-10-28
Release date:2025-06-04
Method:X-RAY DIFFRACTION (2.525 Å)
Cite:SmsC2 dimer from M. jannaschii
To Be Published
7EGK
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BU of 7egk by Molmil
Bicarbonate transporter complex SbtA-SbtB bound to AMP
Descriptor: ADENOSINE MONOPHOSPHATE, Membrane-associated protein SbtB, SODIUM ION, ...
Authors:Fang, S, Huang, X, Zhang, X, Zhang, P.
Deposit date:2021-03-24
Release date:2021-05-26
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Molecular mechanism underlying transport and allosteric inhibition of bicarbonate transporter SbtA.
Proc.Natl.Acad.Sci.USA, 118, 2021
6VXZ
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BU of 6vxz by Molmil
SthK P300A cyclic nucleotide-gated potassium channel in the closed state, in complex with cAMP
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SthK
Authors:Schmidpeter, P.A.M, Rheinberger, J, Nimigean, C.M.
Deposit date:2020-02-25
Release date:2020-11-11
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:Prolyl isomerization controls activation kinetics of a cyclic nucleotide-gated ion channel.
Nat Commun, 11, 2020
3OGJ
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BU of 3ogj by Molmil
Crystal structure of partial apo (92-227) of cGMP-dependent protein kinase
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, PHOSPHATE ION, PRKG1 protein
Authors:Kim, J.J, Huang, G, Kwon, T.K, Zwart, P, Headd, J, Kim, C.
Deposit date:2010-08-16
Release date:2011-05-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.751 Å)
Cite:Co-Crystal Structures of PKG Ibeta (92-227) with cGMP and cAMP Reveal the Molecular Details of Cyclic-Nucleotide Binding
Plos One, 6, 2011
8VT4
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BU of 8vt4 by Molmil
Cryo-EM structure of human ABC transporter ABCC1
Descriptor: CHOLESTEROL HEMISUCCINATE, Multidrug resistance-associated protein 1
Authors:Shinde, O, Li, P.
Deposit date:2024-01-25
Release date:2024-12-25
Last modified:2025-01-29
Method:ELECTRON MICROSCOPY (3.79 Å)
Cite:Structures of ATP-binding cassette transporter ABCC1 reveal the molecular basis of cyclic dinucleotide cGAMP export.
Immunity, 58, 2025
8VVC
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BU of 8vvc by Molmil
Cryo-EM structure of human ABC transporter (hABCC1) with nucleotide-binding domain 2
Descriptor: Multidrug resistance-associated protein 1
Authors:Shinde, O, Li, P.
Deposit date:2024-01-30
Release date:2024-12-25
Last modified:2025-01-29
Method:ELECTRON MICROSCOPY (4.32 Å)
Cite:Structures of ATP-binding cassette transporter ABCC1 reveal the molecular basis of cyclic dinucleotide cGAMP export.
Immunity, 58, 2025
8V4R
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BU of 8v4r by Molmil
Crystal structure of Acetyl-CoA synthetase 2 in complex with AMP and CoA from Candida albicans
Descriptor: ACETIC ACID, ADENOSINE MONOPHOSPHATE, Acetyl-coenzyme A synthetase 2, ...
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2023-11-29
Release date:2023-12-06
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A single Leishmania adenylate-forming enzyme of the ANL superfamily generates both acetyl- and acetoacetyl-CoA.
J.Biol.Chem., 300, 2024
1RDZ
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BU of 1rdz by Molmil
T-STATE STRUCTURE OF THE ARG 243 TO ALA MUTANT OF PIG KIDNEY FRUCTOSE 1,6-BISPHOSPHATASE EXPRESSED IN E. COLI
Descriptor: 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, FRUCTOSE 1,6-BISPHOSPHATASE
Authors:Stec, B, Abraham, R, Giroux, E, Kantrowitz, E.R.
Deposit date:1996-05-17
Release date:1997-01-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structures of the active site mutant (Arg-243-->Ala) in the T and R allosteric states of pig kidney fructose-1,6-bisphosphatase expressed in Escherichia coli.
Protein Sci., 5, 1996
8W0J
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BU of 8w0j by Molmil
Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with a propyne AMP ester inhibitor
Descriptor: 5'-O-{(S)-hydroxy[(prop-2-yn-1-yl)oxy]phosphoryl}adenosine, Acetyl-coenzyme A synthetase 2, CHLORIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-02-13
Release date:2024-02-21
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with a propyne AMP ester inhibitor
To be published
8W0H
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BU of 8w0h by Molmil
Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with an isopropyl AMP ester inhibitor (trigonal form)
Descriptor: 5'-O-{(R)-hydroxy[(propan-2-yl)oxy]phosphoryl}adenosine, Acetyl-coenzyme A synthetase 2, CHLORIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-02-13
Release date:2024-02-21
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with an isopropyl AMP ester inhibitor (trigonal form)
To be published
8W0M
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BU of 8w0m by Molmil
Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with a Acetyl Sulfamate AMP ester inhibitor
Descriptor: 5'-O-(acetylsulfamoyl)adenosine, Acetyl-coenzyme A synthetase 2
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-02-13
Release date:2024-02-21
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with a Acetyl Sulfamate AMP ester inhibitor
To be published
8W0L
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BU of 8w0l by Molmil
Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with a propyne AMP ester inhibitor and CoA
Descriptor: 5'-O-{(S)-hydroxy[(prop-2-yn-1-yl)oxy]phosphoryl}adenosine, Acetyl-coenzyme A synthetase 2, CHLORIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-02-13
Release date:2024-02-21
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with a propyne AMP ester inhibitor and CoA
To be published
8W0B
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BU of 8w0b by Molmil
Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with a cyclopropyl AMP ester inhibitor
Descriptor: 5'-O-[(R)-(cyclopropyloxy)(hydroxy)phosphoryl]adenosine, Acetyl-coenzyme A synthetase 2, GLYCEROL, ...
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-02-13
Release date:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with a cyclopropyl AMP ester inhibitor
To be published
8W0C
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BU of 8w0c by Molmil
Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with a cyclopentyl ester AMP inhibitor
Descriptor: 5'-O-[(S)-(cyclopentyloxy)(hydroxy)phosphoryl]adenosine, Acetyl-coenzyme A synthetase 2, CHLORIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-02-13
Release date:2024-02-21
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with a cyclopentyl ester AMP inhibitor
To be published
8W0D
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BU of 8w0d by Molmil
Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with an isopropyl AMP ester inhibitor
Descriptor: 5'-O-{(R)-hydroxy[(propan-2-yl)oxy]phosphoryl}adenosine, Acetyl-coenzyme A synthetase 2, CHLORIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-02-13
Release date:2024-02-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of Acetyl-CoA synthetase 2 from Candida albicans in complex with an isopropyl AMP ester inhibitor
To be published
1RDY
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BU of 1rdy by Molmil
T-STATE STRUCTURE OF THE ARG 243 TO ALA MUTANT OF PIG KIDNEY FRUCTOSE 1,6-BISPHOSPHATASE EXPRESSED IN E. COLI
Descriptor: 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, FRUCTOSE 1,6-BISPHOSPHATASE
Authors:Stec, B, Abraham, R, Giroux, E, Kantrowitz, E.R.
Deposit date:1996-05-17
Release date:1997-01-11
Last modified:2024-12-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of the active site mutant (Arg-243-->Ala) in the T and R allosteric states of pig kidney fructose-1,6-bisphosphatase expressed in Escherichia coli.
Protein Sci., 5, 1996
7TJ6
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BU of 7tj6 by Molmil
SthK open state, cAMP-bound in the presence of POPA
Descriptor: (2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Putative transcriptional regulator, ...
Authors:Schmidpeter, P.A, Nimigean, C.M.
Deposit date:2022-01-14
Release date:2022-10-26
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Anionic lipids unlock the gates of select ion channels in the pacemaker family.
Nat.Struct.Mol.Biol., 29, 2022
7TJ5
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BU of 7tj5 by Molmil
SthK closed state, cAMP-bound in the presence of POPA
Descriptor: (2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Putative transcriptional regulator, ...
Authors:Schmidpeter, P.A, Nimigean, C.M.
Deposit date:2022-01-14
Release date:2022-10-26
Last modified:2025-06-04
Method:ELECTRON MICROSCOPY (2.41 Å)
Cite:Anionic lipids unlock the gates of select ion channels in the pacemaker family.
Nat.Struct.Mol.Biol., 29, 2022
7TKT
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BU of 7tkt by Molmil
SthK closed state, cAMP-bound in the presence of detergent
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Putative transcriptional regulator, ...
Authors:Rheinberger, J, Schmidpeter, P.A, Nimigean, C.M.
Deposit date:2022-01-17
Release date:2022-10-26
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Anionic lipids unlock the gates of select ion channels in the pacemaker family.
Nat.Struct.Mol.Biol., 29, 2022
3OJ7
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BU of 3oj7 by Molmil
Crystal structure of a histidine triad family protein from entamoeba histolytica, bound to sulfate
Descriptor: Putative histidine triad family protein, SULFATE ION, ZINC ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2010-08-20
Release date:2010-09-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structures of a histidine triad family protein from Entamoeba histolytica bound to sulfate, AMP and GMP.
Acta Crystallogr F Struct Biol Commun, 71, 2015
3OXK
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BU of 3oxk by Molmil
Crystal structure of a histidine triad family protein from Entamoeba histolytica, bound to GMP
Descriptor: ETHANOL, GUANOSINE-5'-MONOPHOSPHATE, Putative histidine triad family protein, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2010-09-21
Release date:2010-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structures of a histidine triad family protein from Entamoeba histolytica bound to sulfate, AMP and GMP.
Acta Crystallogr F Struct Biol Commun, 71, 2015
6V8A
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BU of 6v8a by Molmil
Human CtBP1 (28-375) in complex with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, C-terminal-binding protein 1, CALCIUM ION, ...
Authors:Royer, W.E.
Deposit date:2019-12-10
Release date:2021-02-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:NAD(H) phosphates mediate tetramer assembly of human C-terminal binding protein (CtBP).
J.Biol.Chem., 296, 2021
7LHU
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BU of 7lhu by Molmil
Crystal structure of adenosine-5'-phosphosulfate reductase from Mycobacterium tuberculosis in a complex with product AMP
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE MONOPHOSPHATE, IRON/SULFUR CLUSTER, ...
Authors:Feliciano, P.R, Drennan, C.L.
Deposit date:2021-01-26
Release date:2021-07-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Crystal Structure of the [4Fe-4S] Cluster-Containing Adenosine-5'-phosphosulfate Reductase from Mycobacterium tuberculosis .
Acs Omega, 6, 2021

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