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2GSI
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BU of 2gsi by Molmil
Crystal Structure of a Murine Fab in Complex with an 11 Residue Peptide Derived from Staphylococcal Nuclease
Descriptor: Immunoglobulin (gamma) heavy chain (VH + CH1 fragment), Immunoglobulin (kappa) light chain, SODIUM ION, ...
Authors:Armstrong, A.A, Amzel, L.M.
Deposit date:2006-04-26
Release date:2006-05-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Crystal Structure of a Murine Fab in Complex with an 11 Residue Peptide Derived from Staphylococcal Nuclease
To be Published
2P1Q
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BU of 2p1q by Molmil
Mechanism of Auxin Perception by the TIR1 ubiquitin ligase
Descriptor: 1H-INDOL-3-YLACETIC ACID, Auxin-responsive protein IAA7, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Tan, X, Calderon-Villalobos, L.I.A, Sharon, M, Robinson, C.V, Estelle, M, Zheng, N.
Deposit date:2007-03-06
Release date:2007-04-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Mechanism of auxin perception by the TIR1 ubiquitin ligase.
Nature, 446, 2007
7MQX
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BU of 7mqx by Molmil
P. putida mandelate racemase forms an oxobenzoxaborole adduct with 2-formylphenylboronic acid
Descriptor: (3S)-2,1-benzoxaborole-1,3(3H)-diol, 1,2-ETHANEDIOL, MAGNESIUM ION, ...
Authors:Grandinetti, L, Bearne, S.L, St.Maurice, M.
Deposit date:2021-05-06
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.914 Å)
Cite:Slow-Onset, Potent Inhibition of Mandelate Racemase by 2-Formylphenylboronic Acid. An Unexpected Adduct Clasps the Catalytic Machinery.
Biochemistry, 2021
7JH7
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BU of 7jh7 by Molmil
cardiac actomyosin complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ...
Authors:Galkin, V.E, Schroeder, G.F.
Deposit date:2020-07-20
Release date:2020-10-28
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:High-Resolution Cryo-EM Structure of the Cardiac Actomyosin Complex.
Structure, 29, 2021
2P27
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BU of 2p27 by Molmil
Crystal Structure of Human Pyridoxal Phosphate Phosphatase with Mg2+ at 1.9 A resolution
Descriptor: MAGNESIUM ION, Pyridoxal phosphate phosphatase
Authors:Ramagopal, U.A, Freeman, J, Izuka, M, Toro, R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2007-03-07
Release date:2007-03-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural genomics of protein phosphatases.
J.Struct.Funct.Genom., 8, 2007
7MRL
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BU of 7mrl by Molmil
Structure of HIV-1 matrix domain bound to human tRNALys3
Descriptor: HIV-1 matrix domain, MAGNESIUM ION, tRNA Lys3
Authors:Bou-Nader, C, Zhang, J.
Deposit date:2021-05-07
Release date:2021-08-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:HIV-1 matrix-tRNA complex structure reveals basis for host control of Gag localization.
Cell Host Microbe, 29, 2021
7JKB
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BU of 7jkb by Molmil
2xVH Fab
Descriptor: Anti-Her2, Anti-lysozyme
Authors:Lord, D.M, Zhou, Y.F.
Deposit date:2020-07-28
Release date:2020-11-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Bringing the Heavy Chain to Light: Creating a Symmetric, Bivalent IgG-Like Bispecific.
Antibodies, 9, 2020
2P2L
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BU of 2p2l by Molmil
Rac1-GDP-Zinc Complex
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Ras-related C3 botulinum toxin substrate 1, ZINC ION
Authors:Prehna, G, Stebbins, C.E.
Deposit date:2007-03-07
Release date:2007-05-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Rac1-GDP trimer complex binds zinc with tetrahedral and octahedral coordination, displacing magnesium.
Acta Crystallogr.,Sect.D, 63, 2007
2HAX
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BU of 2hax by Molmil
Crystal structure of Bacillus caldolyticus cold shock protein in complex with hexathymidine
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 5'-D(*TP*TP*TP*TP*TP*T)-3', CALCIUM ION, ...
Authors:Max, K.E.A, Heinemann, U.
Deposit date:2006-06-13
Release date:2007-04-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:Common mode of DNA binding to cold shock domains. Crystal structure of hexathymidine bound to the domain-swapped form of a major cold shock protein from Bacillus caldolyticus.
Febs J., 274, 2007
2GTP
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BU of 2gtp by Molmil
Crystal structure of the heterodimeric complex of human RGS1 and activated Gi alpha 1
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i), alpha-1 subunit, ...
Authors:Soundararajan, M, Turnbull, A.P, Ugochukwu, E, Gorrec, F, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
Deposit date:2006-04-28
Release date:2006-05-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
7ICJ
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BU of 7icj by Molmil
DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CUCL2 (0.1 MILLIMOLAR)
Descriptor: COPPER (II) ION, DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*G)-3'), ...
Authors:Pelletier, H, Sawaya, M.R.
Deposit date:1996-04-19
Release date:1996-11-15
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta
Biochemistry, 35, 1996
7ICI
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BU of 7ici by Molmil
DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CRCL3 (0.1 MILLIMOLAR)
Descriptor: DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ...
Authors:Pelletier, H, Sawaya, M.R.
Deposit date:1996-04-19
Release date:1996-11-15
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta
Biochemistry, 35, 1996
7ICT
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BU of 7ict by Molmil
DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF ZNCL2 AND MGCL2
Descriptor: DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ...
Authors:Pelletier, H, Sawaya, M.R.
Deposit date:1996-04-19
Release date:1996-11-15
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta
Biochemistry, 35, 1996
2HBL
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BU of 2hbl by Molmil
Structure of the yeast nuclear exosome component, Rrp6p, reveals an interplay between the active site and the HRDC domain; Protein in complex with Mn, Zn, and AMP
Descriptor: ADENOSINE MONOPHOSPHATE, Exosome complex exonuclease RRP6, MANGANESE (II) ION, ...
Authors:Midtgaard, S.F, Assenholt, J, Jonstrup, A.T, Van, L.B, Jensen, T.H, Brodersen, D.E.
Deposit date:2006-06-14
Release date:2006-07-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the nuclear exosome component Rrp6p reveals an interplay between the active site and the HRDC domain.
Proc.Natl.Acad.Sci.Usa, 103, 2006
3B3O
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BU of 3b3o by Molmil
Structure of neuronal nos heme domain in complex with a inhibitor (+-)-n1-{cis-4'-[(6"-amino-4"-methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-n2-(4'-chlorobenzyl)ethane-1,2-diamine
Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N-{(3S,4S)-4-[(6-AMINO-4-METHYLPYRIDIN-2-YL)METHYL]PYRROLIDIN-3-YL}-N'-(4-CHLOROBENZYL)ETHANE-1,2-DIAMINE, ...
Authors:Igarashi, J, Li, H, Poulos, T.L.
Deposit date:2007-10-22
Release date:2008-11-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structures of constitutive nitric oxide synthases in complex with de novo designed inhibitors.
J.Med.Chem., 52, 2009
2HBU
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BU of 2hbu by Molmil
Crystal structure of HIF prolyl hydroxylase EGLN-1 in complex with a biologically active inhibitor
Descriptor: Egl nine homolog 1, FE (II) ION, N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE
Authors:Evdokimov, A.G, Walter, R.L, Mekel, M, Pokross, M.E, Kawamoto, R, Boyer, A.
Deposit date:2006-06-14
Release date:2006-06-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of HIF prolyl hydroxylase in complex with a biologically active inhibitor
To be Published
7ME6
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BU of 7me6 by Molmil
Structure of the apo form of YcnI
Descriptor: MALONATE ION, Uncharacterized protein YcnI
Authors:Damle, M, Fisher, O.S.
Deposit date:2021-04-06
Release date:2021-08-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.053 Å)
Cite:The YcnI protein from Bacillus subtilis contains a copper-binding domain.
J.Biol.Chem., 297, 2021
3B2Z
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BU of 3b2z by Molmil
Crystal Structure of ADAMTS4 (apo form)
Descriptor: ADAMTS-4, CALCIUM ION, ZINC ION
Authors:Mosyak, L, Stahl, M, Somers, W.
Deposit date:2007-10-19
Release date:2007-12-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5.
Protein Sci., 17, 2008
2P23
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BU of 2p23 by Molmil
Crystal structure of human FGF19
Descriptor: Fibroblast growth factor 19
Authors:Mohammadi, M.
Deposit date:2007-03-06
Release date:2007-04-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members.
Mol.Cell.Biol., 27, 2007
3GZ2
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BU of 3gz2 by Molmil
Crystal structure of IpgC in complex with an IpaB peptide
Descriptor: Chaperone protein ipgC, GLYCEROL, IMIDAZOLE, ...
Authors:Lokareddy, R.K, Lunelli, M, Kolbe, M.
Deposit date:2009-04-06
Release date:2010-04-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Combination of two separate binding domains defines stoichiometry between type III secretion system chaperone IpgC and translocator protein IpaB
J.Biol.Chem., 285, 2010
7JFO
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BU of 7jfo by Molmil
EPYC1(49-72)-bound Rubisco
Descriptor: LCI5, Ribulose bisphosphate carboxylase large chain, Ribulose bisphosphate carboxylase small chain 2, ...
Authors:Matthies, D, Jonikas, M.C, He, S.
Deposit date:2020-07-17
Release date:2020-11-18
Last modified:2020-12-23
Method:ELECTRON MICROSCOPY (2.13 Å)
Cite:The structural basis of Rubisco phase separation in the pyrenoid.
Nat.Plants, 6, 2020
7JGN
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BU of 7jgn by Molmil
Crystal Structure of the Zn-bound Human Heavy-chain variant 122H-delta C-star with meta-benzenedihyrdoxamate collected at 100K
Descriptor: Ferritin heavy chain, N~1~,N~3~-dihydroxybenzene-1,3-dicarboxamide, SODIUM ION, ...
Authors:Bailey, J.B, Tezcan, F.A.
Deposit date:2020-07-19
Release date:2020-10-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Tunable and Cooperative Thermomechanical Properties of Protein-Metal-Organic Frameworks.
J.Am.Chem.Soc., 142, 2020
7ICE
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BU of 7ice by Molmil
DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF CACL2
Descriptor: DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), DNA (5'-D(P*CP*AP*GP*AP*TP*G)-3'), PROTEIN (DNA POLYMERASE BETA), ...
Authors:Pelletier, H, Sawaya, M.R.
Deposit date:1996-04-19
Release date:1996-11-15
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta
Biochemistry, 35, 1996
7MJA
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BU of 7mja by Molmil
HLA-A*24:02 bound to Neuroblastoma derived PHOX2B peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Toor, J.S, Tripathi, S.M, Truong, H.V, Yarmarkovich, M, Maris, J.M, Sgourakis, N.G.
Deposit date:2021-04-19
Release date:2021-08-18
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs.
Nature, 599, 2021
3GZU
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BU of 3gzu by Molmil
VP7 recoated rotavirus DLP
Descriptor: Inner capsid protein VP2, Intermediate capsid protein VP6, ZINC ION
Authors:Chen, J.Z, Settembre, E.C, Harrison, S.C, Grigorieff, N.
Deposit date:2009-04-07
Release date:2009-07-14
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM.
Proc.Natl.Acad.Sci.USA, 106, 2009

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