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7ANW
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BU of 7anw by Molmil
hSARM1 NAD+ complex
Descriptor: NAD(+) hydrolase SARM1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Sporny, M, Guez-Haddad, J, Khazma, T, Yaron, A, Mim, C, Isupov, M.N, Zalk, R, Dessau, M, Hons, M, Opatowsky, Y.
Deposit date:2020-10-13
Release date:2020-11-11
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Structural basis for SARM1 inhibition and activation under energetic stress.
Elife, 9, 2020
7AO8
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BU of 7ao8 by Molmil
Structure of the MTA1/HDAC1/MBD2 NURD deacetylase complex
Descriptor: Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, Metastasis-associated protein MTA1, ...
Authors:Millard, C.J, Fairall, L, Ragan, T.J, Savva, C.G, Schwabe, J.W.R.
Deposit date:2020-10-14
Release date:2020-11-11
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:The topology of chromatin-binding domains in the NuRD deacetylase complex.
Nucleic Acids Res., 48, 2020
2J3Z
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BU of 2j3z by Molmil
Crystal structure of the enzymatic component C2-I of the C2-toxin from Clostridium botulinum at pH 6.1
Descriptor: C2 TOXIN COMPONENT I, COBALT (II) ION, GLYCEROL, ...
Authors:Schleberger, C, Hochmann, H, Barth, H, Aktories, K, Schulz, G.E.
Deposit date:2006-08-23
Release date:2006-10-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and Action of the Binary C2 Toxin from Clostridium Botulinum.
J.Mol.Biol., 364, 2006
2LZQ
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BU of 2lzq by Molmil
Structure of NS2(32-57) GBVB protein
Descriptor: NS2 peptide
Authors:Montserret, R, Penin, F, Martin, A.
Deposit date:2012-10-08
Release date:2014-04-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NS2 Proteins of GB Virus B and Hepatitis C Virus Share Common Protease Activities and Membrane Topologies.
J.Virol., 88, 2014
7SV1
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BU of 7sv1 by Molmil
Carbonic Anhydrase IX-mimic Complexed with 3-((2-((Naphthalen-2-ylmethyl)(4-sulfamoylphenethyl)amino)-2-oxoethyl)(phenethyl)amino)propanoic acid
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Carbonic anhydrase 2, N~2~-(3-aminopropyl)-N-[(4-fluorophenyl)methyl]-N~2~-(2-phenylethyl)-N-[2-(4-sulfamoylphenyl)ethyl]glycinamide, ...
Authors:Combs, J.E, McKenna, R.
Deposit date:2021-11-18
Release date:2022-04-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.559 Å)
Cite:The three-tails approach as a new strategy to improve selectivity of action of sulphonamide inhibitors against tumour-associated carbonic anhydrase IX and XII.
J Enzyme Inhib Med Chem, 37, 2022
3IKJ
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BU of 3ikj by Molmil
Structural characterization for the nucleotide binding ability of subunit A mutant S238A of the A1AO ATP synthase
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, V-type ATP synthase alpha chain
Authors:Kumar, A, Manimekali, M.S.S, Balakrishna, A.M, Jeyakanthan, J, Gruber, G.
Deposit date:2009-08-06
Release date:2010-01-12
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Nucleotide binding states of subunit A of the A-ATP synthase and the implication of P-loop switch in evolution.
J.Mol.Biol., 396, 2010
2ICE
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BU of 2ice by Molmil
CRIg bound to C3c
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C3 alpha chain, ...
Authors:Wiesmann, C.
Deposit date:2006-09-12
Release date:2006-11-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of C3b in complex with CRIg gives insights into regulation of complement activation.
Nature, 444, 2006
5KMY
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BU of 5kmy by Molmil
Crystal structure of tryptophan synthase subunit alpha from Legionella pneumophila str. Paris
Descriptor: Tryptophan synthase alpha chain
Authors:Nocek, B, Hatzos-Skintges, C, Endres, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2016-06-27
Release date:2016-08-03
Last modified:2017-02-08
Method:X-RAY DIFFRACTION (1.908 Å)
Cite:Crystal structure of tryptophan synthase subunit alpha from Legionella pneumophila str. Paris
To Be Published
7KRM
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BU of 7krm by Molmil
Putative FabG bound to NADH from Acinetobacter baumannii
Descriptor: 3-oxoacyl-[acyl-carrier-protein] reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Shaw, K.I, Smith, K.M, Cross, E.M.
Deposit date:2020-11-20
Release date:2020-12-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Putative FabG bound to NADH from Acinetobacter baumannii
To Be Published
3IKY
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BU of 3iky by Molmil
Structural model of ParM filament in the open state by cryo-EM
Descriptor: Plasmid segregation protein parM
Authors:Galkin, V.E, Orlova, A, Rivera, C, Mullins, R.D, Egelman, E.H.
Deposit date:2009-08-06
Release date:2009-09-29
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (18 Å)
Cite:Structural polymorphism of the ParM filament and dynamic instability
Structure, 17, 2009
2ZWZ
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BU of 2zwz by Molmil
alpha-L-fucosidase complexed with inhibitor, Core1
Descriptor: (2R,3R,4R,5R,6S)-2-(aminomethyl)-6-methylpiperidine-3,4,5-triol, Alpha-L-fucosidase, putative
Authors:Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J.
Deposit date:2008-12-19
Release date:2009-12-08
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
Angew.Chem.Int.Ed.Engl., 49, 2010
7ARY
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BU of 7ary by Molmil
Twist-Tower_twist-corrected-variant
Descriptor: SCAFFOLD STRAND, STAPLE STRAND
Authors:Kube, M, Kohler, F, Feigl, E, Nagel-Yuksel, B, Willner, E.M, Funke, J.J, Gerling, T, Stommer, P, Honemann, M.N, Martin, T.G, Scheres, S.H.W, Dietz, H.
Deposit date:2020-10-26
Release date:2020-11-18
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution.
Nat Commun, 11, 2020
7KUS
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BU of 7kus by Molmil
Crystal Structure of Danio rerio Histone Deacetylase 10 H137A Mutant in Complex with N8-Acetylspermidine (Tetrahedral Intermediate)
Descriptor: 1,2-ETHANEDIOL, 1-({4-[(3-aminopropyl)amino]butyl}amino)ethane-1,1-diol, DI(HYDROXYETHYL)ETHER, ...
Authors:Herbst-Gervasoni, C.J, Christianson, D.W.
Deposit date:2020-11-25
Release date:2021-02-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray Crystallographic Snapshots of Substrate Binding in the Active Site of Histone Deacetylase 10.
Biochemistry, 60, 2021
7TDO
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BU of 7tdo by Molmil
Cryo-EM structure of transmembrane AAA+ protease FtsH in the ADP state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent zinc metalloprotease FtsH
Authors:Liu, W, Schoonen, M, Wang, T, McSweeney, S, Liu, Q.
Deposit date:2022-01-02
Release date:2022-04-06
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Cryo-EM structure of transmembrane AAA+ protease FtsH in the ADP state.
Commun Biol, 5, 2022
2ZXD
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BU of 2zxd by Molmil
alpha-L-fucosidase complexed with inhibitor, iso-6FNJ
Descriptor: (2S,3R,4S,5R)-2-(1-methylethyl)piperidine-3,4,5-triol, Alpha-L-fucosidase, putative
Authors:Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J.
Deposit date:2008-12-22
Release date:2009-12-08
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
Angew.Chem.Int.Ed.Engl., 49, 2010
7SNE
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BU of 7sne by Molmil
Pertussis toxin S1 subunit bound to BaAD
Descriptor: Pertussis toxin subunit 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3S,4R,5S)-5-(3-carbamoylanilino)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen diphosphate (non-preferred name)
Authors:Littler, D.R, Beddoe, T.
Deposit date:2021-10-28
Release date:2022-04-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.00011 Å)
Cite:Crystal structures of pertussis toxin with NAD + and analogs provide structural insights into the mechanism of its cytosolic ADP-ribosylation activity.
J.Biol.Chem., 298, 2022
2ZXY
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BU of 2zxy by Molmil
Crystal Structure of Cytochrome c555 from Aquifex aeolicus
Descriptor: Cytochrome c552, HEME C
Authors:Obuchi, M, Kawahara, K, Motooka, D, Nakamura, S, Yamanaka, M, Takeda, T, Uchiyama, S, Kobayashi, Y, Ohkubo, T, Sambongi, Y.
Deposit date:2009-01-09
Release date:2009-08-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Hyperstability and crystal structure of cytochrome c(555) from hyperthermophilic Aquifex aeolicus
Acta Crystallogr.,Sect.D, 65, 2009
7SP8
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BU of 7sp8 by Molmil
Chlorella virus Hyaluronan Synthase bound to UDP-GlcNAc
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, CHOLESTEROL HEMISUCCINATE, Hyaluronan synthase, ...
Authors:Maloney, F.P, Kuklewicz, J, Zimmer, J.
Deposit date:2021-11-02
Release date:2022-04-06
Last modified:2022-04-20
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structure, substrate recognition and initiation of hyaluronan synthase.
Nature, 604, 2022
7E5E
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BU of 7e5e by Molmil
Crystal structure of GDP-bound GNAS in complex with the cyclic peptide inhibitor GD20
Descriptor: CHLORIDE ION, GD20, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Hu, Q, Dai, S, Shokat, K.M.
Deposit date:2021-02-18
Release date:2022-03-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:State-selective modulation of heterotrimeric G alpha s signaling with macrocyclic peptides.
Cell, 185, 2022
3AC0
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BU of 3ac0 by Molmil
Crystal structure of Beta-glucosidase from Kluyveromyces marxianus in complex with glucose
Descriptor: Beta-glucosidase I, beta-D-glucopyranose
Authors:Yoshida, E, Hidaka, M, Fushinobu, S, Katayama, T, Kumagai, H.
Deposit date:2009-12-25
Release date:2010-08-11
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Role of a PA14 domain in determining substrate specificity of a glycoside hydrolase family 3 beta-glucosidase from Kluyveromyces marxianus.
Biochem.J., 431, 2010
7SP7
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BU of 7sp7 by Molmil
Chlorella virus hyaluronan synthase inhibited by UDP
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, CHOLESTEROL HEMISUCCINATE, Hyaluronan synthase, ...
Authors:Maloney, F.P, Kuklewicz, J, Zimmer, J.
Deposit date:2021-11-02
Release date:2022-04-06
Last modified:2022-04-20
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure, substrate recognition and initiation of hyaluronan synthase.
Nature, 604, 2022
2ZYI
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BU of 2zyi by Molmil
A. Fulgidus lipase with fatty acid fragment and calcium
Descriptor: CALCIUM ION, Lipase, putative, ...
Authors:Chen, C.K, Ko, T.P, Guo, R.T, Wang, A.H.
Deposit date:2009-01-22
Release date:2009-06-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the alkalohyperthermophilic Archaeoglobus fulgidus lipase contains a unique C-terminal domain essential for long-chain substrate binding.
J.Mol.Biol., 390, 2009
2MHR
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BU of 2mhr by Molmil
STRUCTURE OF MYOHEMERYTHRIN IN THE AZIDOMET STATE AT 1.7(SLASH)1.3 ANGSTROMS RESOLUTION
Descriptor: AZIDE ION, MU-OXO-DIIRON, MYOHEMERYTHRIN, ...
Authors:Sheriff, S, Hendrickson, W.A.
Deposit date:1987-04-20
Release date:1987-10-16
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure of myohemerythrin in the azidomet state at 1.7/1.3 A resolution.
J.Mol.Biol., 197, 1987
7SUY
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BU of 7suy by Molmil
Carbonic Anhydrase IX-mimic Complexed with 2-((3-Aminopropyl)(phenethyl)amino)-N-(4-fluorobenzyl)-N-(4-sulfamoylphenethyl)acetamide
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Carbonic anhydrase 2, N-[(furan-2-yl)methyl]-N-[2-(4-sulfamoylphenyl)ethyl]glycinamide, ...
Authors:Combs, J.E, McKenna, R.
Deposit date:2021-11-18
Release date:2022-04-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.405 Å)
Cite:The three-tails approach as a new strategy to improve selectivity of action of sulphonamide inhibitors against tumour-associated carbonic anhydrase IX and XII.
J Enzyme Inhib Med Chem, 37, 2022
7E73
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BU of 7e73 by Molmil
Crystal structure of human ERK2 mutant (Y36H)
Descriptor: Mitogen-activated protein kinase 1, SULFATE ION
Authors:Park, Y.S, Kim, M, Ryu, S.E.
Deposit date:2021-02-25
Release date:2022-03-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural mechanism of inhibitor-resistance by ERK2 mutations
Biodesign, 9, 2021

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