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3OVS
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BU of 3ovs by Molmil
How the CCA-adding Enzyme Selects Adenine over Cytosine in Position 76 of tRNA
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, CCA-Adding Enzyme, ...
Authors:Pan, B.C, Xiong, Y, Steitz, T.A.
Deposit date:2010-09-17
Release date:2010-12-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:How the CCA-Adding Enzyme Selects Adenine over Cytosine at Position 76 of tRNA.
Science, 330, 2010
7WM4
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BU of 7wm4 by Molmil
Cryo-EM structure of tetrameric TLR3 in complex with dsRNA (90 bp)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RNA (81-MER), ...
Authors:Sakaniwa, K, Ohto, U, Shimizu, T.
Deposit date:2022-01-14
Release date:2023-01-25
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:TLR3 forms a laterally aligned multimeric complex along double-stranded RNA for efficient signal transduction.
Nat Commun, 14, 2023
3IZ4
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BU of 3iz4 by Molmil
Modified E. coli tmRNA in the resume state with the tRNA-like domain in the ribosomal P site interacting with the SmpB
Descriptor: Modified E. coli transfer-messenger RNA, SsrA-binding protein
Authors:Hashem, Y, Fu, J, Frank, J.
Deposit date:2010-09-21
Release date:2010-10-20
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (13.6 Å)
Cite:Visualizing the transfer-messenger RNA as the ribosome resumes translation.
Embo J., 29, 2010
3AEV
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BU of 3aev by Molmil
Crystal structure of a/eIF2alpha-aDim2p-rRNA complex from Pyrococcus horikoshii OT3
Descriptor: Putative uncharacterized protein PH1566, RNA (5'-R(*GP*GP*AP*UP*CP*AP*CP*CP*UP*CP*C)-3'), Translation initiation factor 2 subunit alpha
Authors:Tanokura, M, Jia, M.Z, Nagata, K.
Deposit date:2010-02-10
Release date:2010-04-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:An archaeal Dim2-like protein, aDim2p, forms a ternary complex with a/eIF2 alpha and the 3' end fragment of 16S rRNA
J.Mol.Biol., 398, 2010
2AZ2
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BU of 2az2 by Molmil
Flock House virus B2-dsRNA Complex (P4122)
Descriptor: 5'-R(*GP*CP*AP*(5BU)P*GP*GP*AP*CP*GP*CP*GP*(5BU)P*CP*CP*AP*(5BU)P*GP*C)-3', B2 protein
Authors:Chao, J.A, Lee, J.H, Chapados, B.R, Debler, E.W, Schneemann, A, Williamson, J.R.
Deposit date:2005-09-09
Release date:2005-10-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Dual modes of RNA-silencing suppression by Flock House virus protein B2.
Nat.Struct.Mol.Biol., 12, 2005
6VPB
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BU of 6vpb by Molmil
A novel membrane-bound 6-phosphogluconate dehydrogenase from the acetic acid bacteria Gluconacetobacter diazotrophicus (Gd6PGD)
Descriptor: 6-phosphogluconate dehydrogenase, DI(HYDROXYETHYL)ETHER, ISOPROPYL ALCOHOL, ...
Authors:Rodriguez-Romero, A, Rodriguez-Hernandez, A.
Deposit date:2020-02-02
Release date:2020-07-22
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:The structure of a novel membrane-associated 6-phosphogluconate dehydrogenase from Gluconacetobacter diazotrophicus (Gd6PGD) reveals a subfamily of short-chain 6PGDs.
Febs J., 288, 2021
6SVS
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BU of 6svs by Molmil
Crystal Structure of U:A-U-rich RNA triple helix with 11 consecutive base triples
Descriptor: ADENOSINE-5'-PHOSPHATE-2',3'-CYCLIC PHOSPHATE, CALCIUM ION, GLYCEROL, ...
Authors:Ruszkowska, A, Ruszkowski, M, Hulewicz, J.P, Dauter, Z, Brown, J.A.
Deposit date:2019-09-18
Release date:2020-01-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular structure of a U•A-U-rich RNA triple helix with 11 consecutive base triples.
Nucleic Acids Res., 48, 2020
1DI2
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BU of 1di2 by Molmil
CRYSTAL STRUCTURE OF A DSRNA-BINDING DOMAIN COMPLEXED WITH DSRNA: MOLECULAR BASIS OF DOUBLE-STRANDED RNA-PROTEIN INTERACTIONS
Descriptor: DOUBLE STRANDED RNA BINDING PROTEIN A, RNA (5'-R(*GP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3')
Authors:Ryter, J.M, Schultz, S.C.
Deposit date:1999-11-28
Release date:1999-12-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular basis of double-stranded RNA-protein interactions: structure of a dsRNA-binding domain complexed with dsRNA.
EMBO J., 17, 1998
4MDX
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BU of 4mdx by Molmil
Crystal structure of Bacillus subtilis MazF in complex with RNA
Descriptor: IODIDE ION, RNA, mRNA, ...
Authors:Simanshu, D.K, Patel, D.J.
Deposit date:2013-08-23
Release date:2013-10-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Basis of mRNA Recognition and Cleavage by Toxin MazF and Its Regulation by Antitoxin MazE in Bacillus subtilis.
Mol.Cell, 52, 2013
8OVD
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BU of 8ovd by Molmil
Respiratory supercomplex (III2-IV2) from Mycobacterium smegmatis
Descriptor: (1R)-2-(dodecanoyloxy)-1-[(phosphonooxy)methyl]ethyl tetradecanoate, (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2S)-1-(hexadecanoyloxy)propan-2-yl (10S)-10-methyloctadecanoate, ...
Authors:Kovalova, T, Krol, S, Sjostrand, D, Riepl, D, Gamiz-Hernandez, A, Brzezinski, P, Kaila, V, Hogbom, M.
Deposit date:2023-04-25
Release date:2024-07-17
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Long-range charge transfer mechanism of the III 2 IV 2 mycobacterial supercomplex.
Nat Commun, 15, 2024
8OVC
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BU of 8ovc by Molmil
Respiratory supercomplex (III2-IV2) from Mycobacterium smegmatis
Descriptor: (1R)-2-(dodecanoyloxy)-1-[(phosphonooxy)methyl]ethyl tetradecanoate, (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2S)-1-(hexadecanoyloxy)propan-2-yl (10S)-10-methyloctadecanoate, ...
Authors:Kovalova, T, Krol, S, Sjostrand, D, Riepl, D, Gamiz-Hernandez, A, Brzezinski, P, Kaila, V, Hogbom, M.
Deposit date:2023-04-25
Release date:2024-07-17
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Long-range charge transfer mechanism of the III 2 IV 2 mycobacterial supercomplex.
Nat Commun, 15, 2024
1OB5
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BU of 1ob5 by Molmil
T. aquaticus elongation factor EF-Tu complexed with the antibiotic enacyloxin IIa, a GTP analog, and Phe-tRNA
Descriptor: ELONGATION FACTOR TU, ENACYLOXIN IIA, MAGNESIUM ION, ...
Authors:Dahlberg, C, Nielsen, R.C, Parmeggiani, A, Nyborg, J, Nissen, P.
Deposit date:2003-01-24
Release date:2005-10-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Enacyloxin Iia Pinpoints a Binding Pocket of Elongation Factor TU for Development of Novel Antibiotics.
J.Biol.Chem., 281, 2006
6DPB
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BU of 6dpb by Molmil
Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 8 mM Mn2+ and 200 mM K+ for 40 s at 21 C
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*AP*TP*GP*T)-3'), GLYCEROL, ...
Authors:Samara, N.L, Yang, W.
Deposit date:2018-06-09
Release date:2018-08-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.324 Å)
Cite:Cation trafficking propels RNA hydrolysis.
Nat. Struct. Mol. Biol., 25, 2018
6EOJ
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BU of 6eoj by Molmil
PolyA polymerase module of the cleavage and polyadenylation factor (CPF) from Saccharomyces cerevisiae
Descriptor: Polyadenylation factor subunit 2,Polyadenylation factor subunit 2, Protein CFT1, ZINC ION, ...
Authors:Casanal, A, Kumar, A, Hill, C.H, Emsley, P, Passmore, L.A.
Deposit date:2017-10-09
Release date:2017-11-15
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Architecture of eukaryotic mRNA 3'-end processing machinery.
Science, 358, 2017
2BE0
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BU of 2be0 by Molmil
Complex Between Paromomycin Derivative JS5-39 and the 16S-Rrna A-Site.
Descriptor: (2S,3S,4R,5R,6R)-5-AMINO-2-(AMINOMETHYL)-6-((2R,3R,4R,5S)-5-((1R,2R,3S,5R,6S)-3,5-DIAMINO-2-((2S,3R,4R,5S,6R)-3-AMINO-4 ,5-DIHYDROXY-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-6-HYDROXYCYCLOHEXYLOXY)-2-(HYDROXYMETHYL)-4-(2-((R)-PIPERIDI N-3-YLMETHYLAMINO)ETHOXY)-TETRAHYDROFURAN-3-YLOXY)-TETRAHYDRO-2H-PYRAN-3,4-DIOL, 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3'
Authors:Francois, B, Westhof, E.
Deposit date:2005-10-21
Release date:2005-12-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Antibacterial aminoglycosides with a modified mode of binding to the ribosomal-RNA decoding site
ANGEW.CHEM.INT.ED.ENGL., 43, 2004
6DPA
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BU of 6dpa by Molmil
Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 4 mM Mn2+ and 200 mM K+ for 40 s at 21 C
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*AP*TP*GP*T)-3'), GLYCEROL, ...
Authors:Samara, N.L, Yang, W.
Deposit date:2018-06-09
Release date:2018-08-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.489 Å)
Cite:Cation trafficking propels RNA hydrolysis.
Nat. Struct. Mol. Biol., 25, 2018
6DPF
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BU of 6dpf by Molmil
Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 40 mM Mn2+ and 200 mM K+ for 40 s at 21 C
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*AP*TP*GP*T)-3'), GLYCEROL, ...
Authors:Samara, N.L, Yang, W.
Deposit date:2018-06-09
Release date:2018-08-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Cation trafficking propels RNA hydrolysis.
Nat. Struct. Mol. Biol., 25, 2018
7XSP
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BU of 7xsp by Molmil
Structure of gRAMP-target RNA
Descriptor: RAMP superfamily protein, RNA (35-MER), RNA (5'-R(P*GP*GP*GP*GP*CP*AP*GP*AP*AP*AP*AP*UP*UP*GP*G)-3'), ...
Authors:Feng, Y, Zhang, L.X.
Deposit date:2022-05-15
Release date:2022-11-09
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Target RNA activates the protease activity of Craspase to confer antiviral defense.
Mol.Cell, 82, 2022
7XSR
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BU of 7xsr by Molmil
Structure of Craspase-target RNA
Descriptor: CHAT domain protein, RAMP superfamily protein, RNA (34-MER), ...
Authors:Feng, Y, Zhang, L.
Deposit date:2022-05-15
Release date:2022-11-09
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Target RNA activates the protease activity of Craspase to confer antiviral defense.
Mol.Cell, 82, 2022
7ELT
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BU of 7elt by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Trp-AMP
Descriptor: TRYPTOPHANYL-5'AMP, Tryptophan--tRNA ligase
Authors:Xu, M, Chen, S.
Deposit date:2021-04-12
Release date:2022-02-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
7ENS
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BU of 7ens by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Indolmycin and ATP
Descriptor: (5S)-5-[(1R)-1-(1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4(5H)-one, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Xu, M, Chen, S.
Deposit date:2021-04-19
Release date:2022-02-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
7ENT
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BU of 7ent by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Y-13 and ATP
Descriptor: (5S)-2-(methylamino)-5-[(1R)-1-(4-methyl-1H-indol-3-yl)ethyl]-1,3-oxazol-4-one, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Xu, M, Chen, S.
Deposit date:2021-04-19
Release date:2022-02-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
1I9V
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BU of 1i9v by Molmil
CRYSTAL STRUCTURE ANALYSIS OF A TRNA-NEOMYCIN COMPLEX
Descriptor: MAGNESIUM ION, NEOMYCIN, PHENYLALANINE TRANSFER RNA
Authors:Mikkelsen, N.E, Johansson, K, Virtanen, A, Kirsebom, L.A.
Deposit date:2001-03-21
Release date:2001-06-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Aminoglycoside binding displaces a divalent metal ion in a tRNA-neomycin B complex.
Nat.Struct.Biol., 8, 2001
3K0J
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BU of 3k0j by Molmil
Crystal structure of the E. coli ThiM riboswitch in complex with thiamine pyrophosphate and the U1A crystallization module
Descriptor: MAGNESIUM ION, RNA (87-MER), THIAMINE DIPHOSPHATE, ...
Authors:Kulshina, N, Edwards, T.E, Ferre-D'Amare, A.R.
Deposit date:2009-09-24
Release date:2009-12-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Thermodynamic analysis of ligand binding and ligand binding-induced tertiary structure formation by the thiamine pyrophosphate riboswitch.
Rna, 16, 2010
2YH1
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BU of 2yh1 by Molmil
Model of human U2AF65 tandem RRM1 and RRM2 domains with eight-site uridine binding
Descriptor: 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP)-3', SPLICING FACTOR U2AF 65 KDA SUBUNIT
Authors:Mackereth, C.D, Madl, T, Simon, B, Zanier, K, Gasch, A, Sattler, M.
Deposit date:2011-04-26
Release date:2011-07-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Multi-Domain Conformational Selection Underlies Pre-Mrna Splicing Regulation by U2Af
Nature, 475, 2011

223532

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