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8UQ4
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BU of 8uq4 by Molmil
Structure of human RyR2-S2808D in the subprimed state in the presence of H2O2/NOC-12/GSH
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
Authors:Miotto, M.C, Marks, A.R.
Deposit date:2023-10-23
Release date:2023-11-15
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
3QTY
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BU of 3qty by Molmil
Crystal structure of Phosphoribosylaminoimidazole Synthetase from Francisella tularensis complexed with pyrophosphate
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, PHOSPHATE ION, ...
Authors:Maltseva, N, Kim, Y, Hasseman, J, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-02-23
Release date:2011-03-16
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of Phosphoribosylaminoimidazole Synthetase from Francisella tularensis complexed with pyrophosphate
To be Published
4O7T
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BU of 4o7t by Molmil
SAICAR synthetase (Type-2) in complex with ADP, ASP and TMP
Descriptor: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ASPARTIC ACID, ...
Authors:Manjunath, K, Jeyakanthan, J, Sekar, K.
Deposit date:2013-12-26
Release date:2014-12-31
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:SAICAR synthetase (Type-2) in complex with ADP, ASP and TMP
To be Published
4O7R
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BU of 4o7r by Molmil
SAICAR synthetase (Type-2) in complex with UMP/UDP
Descriptor: ACETATE ION, PHOSPHATE ION, Phosphoribosylaminoimidazole-succinocarboxamide synthase, ...
Authors:Manjunath, K, Jeyakanthan, J, Sekar, K.
Deposit date:2013-12-26
Release date:2014-12-31
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:SAICAR synthetase (Type-2) in complex with UMP/UDP
To be Published
4O84
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BU of 4o84 by Molmil
SAICAR synthetase (Type-1) in complex with GMP
Descriptor: 1,4-BUTANEDIOL, CADMIUM ION, GUANOSINE-5'-MONOPHOSPHATE, ...
Authors:Manjunath, K, Jeyakanthan, J, Sekar, K.
Deposit date:2013-12-26
Release date:2014-12-31
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:SAICAR synthetase (Type-1) in complex with GMP
To be Published
3PPF
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BU of 3ppf by Molmil
Crystal structure of the Candida albicans methionine synthase by surface entropy reduction, alanine variant without zinc
Descriptor: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
Authors:Ubhi, D, Kavanagh, K, Monzingo, A.F, Robertus, J.D.
Deposit date:2010-11-24
Release date:2011-10-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of Candida albicans methionine synthase determined by employing surface residue mutagenesis.
Arch.Biochem.Biophys., 513, 2011
6VCU
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BU of 6vcu by Molmil
Homo sapiens FKBP12 protein bound with APX879 in P32 space group
Descriptor: ACETATE ION, N'-[(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-1,20,21-trioxo-8-(prop-2-en-1-yl)-1,3,4,5,6,8,11,12,13,14,15,16,17,18,19,20,21,23,24,25,26,26a-docosahydro-7H-15,19-epoxypyrido[2,1-c][1,4]oxazacyclotricosin-7-ylidene]acetohydrazide, Peptidyl-prolyl cis-trans isomerase FKBP1A
Authors:Gobeil, S, Spicer, L.
Deposit date:2019-12-23
Release date:2020-12-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Leveraging Fungal and Human Calcineurin-Inhibitor Structures, Biophysical Data, and Dynamics To Design Selective and Nonimmunosuppressive FK506 Analogs.
Mbio, 12, 2021
3NRB
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BU of 3nrb by Molmil
Crystal structure of a formyltetrahydrofolate deformylase (purU, PP_1943) from PSEUDOMONAS PUTIDA KT2440 at 2.05 A resolution
Descriptor: 1,2-ETHANEDIOL, CITRATE ANION, Formyltetrahydrofolate deformylase, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2010-06-30
Release date:2010-07-28
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of a formyltetrahydrofolate deformylase (purU, PP_1943) from PSEUDOMONAS PUTIDA KT2440 at 2.05 A resolution
To be published
8STD
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BU of 8std by Molmil
S127A variant of LarB, a carboxylase/hydrolase involved in synthesis of the cofactor for lactate racemase, in complex with authentic substrate NaAD and soaked with CS2
Descriptor: MAGNESIUM ION, NICOTINIC ACID ADENINE DINUCLEOTIDE, Pyridinium-3,5-biscarboxylic acid mononucleotide synthase
Authors:Chatterjee, S, Rankin, J.A, Hu, J, Hausinger, R.P.
Deposit date:2023-05-10
Release date:2023-12-27
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of the LarB-Substrate Complex and Identification of a Reaction Intermediate during Nickel-Pincer Nucleotide Cofactor Biosynthesis.
Biochemistry, 62, 2023
8SOQ
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BU of 8soq by Molmil
S127A variant of LarB, a carboxylase/hydrolase involved in synthesis of the cofactor for lactate racemase, in complex with authentic substrate NaAD
Descriptor: MAGNESIUM ION, NICOTINIC ACID ADENINE DINUCLEOTIDE, Pyridinium-3,5-biscarboxylic acid mononucleotide synthase
Authors:Chatterjee, S, Rankin, J.A, Hu, J, Hausinger, R.P.
Deposit date:2023-04-29
Release date:2023-12-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the LarB-Substrate Complex and Identification of a Reaction Intermediate during Nickel-Pincer Nucleotide Cofactor Biosynthesis.
Biochemistry, 62, 2023
3OET
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BU of 3oet by Molmil
D-Erythronate-4-Phosphate Dehydrogenase complexed with NAD
Descriptor: Erythronate-4-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Filippova, E.V, Wawrzak, Z, Onopriyenko, O, Savchenko, A, Edwards, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2010-08-13
Release date:2010-08-25
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:D-Erythronate-4-Phosphate Dehydrogenase complexed with NAD
To be Published
6TNH
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BU of 6tnh by Molmil
Deoxyguanylosuccinate synthase (DgsS) quaternary structure with AMPPcP, dGMP, Asp, Magnesium at 2.21 Angstrom resolution
Descriptor: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, ASPARTIC ACID, Adenylosuccinate synthetase, ...
Authors:Sleiman, D, Loc'h, J, Haouz, A, Kaminski, P.A.
Deposit date:2019-12-08
Release date:2020-12-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:A third purine biosynthetic pathway encoded by aminoadenine-based viral DNA genomes.
Science, 372, 2021
6VTN
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BU of 6vtn by Molmil
Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM557
Descriptor: Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ...
Authors:Deng, X, Phillips, M.
Deposit date:2020-02-13
Release date:2020-04-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Lead Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series for the Treatment of Malaria.
J.Med.Chem., 63, 2020
3PNU
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BU of 3pnu by Molmil
2.4 Angstrom Crystal Structure of Dihydroorotase (pyrC) from Campylobacter jejuni.
Descriptor: Dihydroorotase, PHOSPHATE ION, ZINC ION
Authors:Minasov, G, Halavaty, A, Shuvalova, L, Dubrovska, I, Winsor, J, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2010-11-19
Release date:2010-12-01
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:2.4 Angstrom Crystal Structure of Dihydroorotase (pyrC) from Campylobacter jejuni.
TO BE PUBLISHED
3PPH
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BU of 3pph by Molmil
Crystal structure of the Candida albicans methionine synthase by surface entropy reduction, threonine variant
Descriptor: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
Authors:Ubhi, D, Kavanagh, K, Monzingo, A.F, Robertus, J.D.
Deposit date:2010-11-24
Release date:2011-10-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of Candida albicans methionine synthase determined by employing surface residue mutagenesis.
Arch.Biochem.Biophys., 513, 2011
4O7N
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BU of 4o7n by Molmil
SAICAR synthetase (Type-2) in complex with ADP
Descriptor: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Manjunath, K, Jeyakanthan, J, Sekar, K.
Deposit date:2013-12-26
Release date:2014-12-31
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:SAICAR synthetase (Type-2) in complex with ADP
To be Published
4O7Y
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BU of 4o7y by Molmil
SAICAR synthetase (Type-2) in complex with CMP
Descriptor: ACETATE ION, CYTIDINE-5'-MONOPHOSPHATE, PHOSPHATE ION, ...
Authors:Manjunath, K, Jeyakanthan, J, Sekar, K.
Deposit date:2013-12-26
Release date:2014-12-31
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:SAICAR synthetase (Type-2) in complex with CMP
To be Published
4OC9
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BU of 4oc9 by Molmil
2.35 Angstrom resolution crystal structure of putative O-acetylhomoserine (thiol)-lyase (metY) from Campylobacter jejuni subsp. jejuni NCTC 11168 with N'-Pyridoxyl-Lysine-5'-Monophosphate at position 205
Descriptor: GLYCEROL, IMIDAZOLE, PHOSPHATE ION, ...
Authors:Halavaty, A.S, Brunzelle, J.S, Wawrzak, Z, Onopriyenko, O, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2014-01-08
Release date:2014-03-12
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:2.35 Angstrom resolution crystal structure of putative O-acetylhomoserine (thiol)-lyase (metY) from Campylobacter jejuni subsp. jejuni NCTC 11168 with N'-Pyridoxyl-Lysine-5'-Monophosphate at position 205
To be Published
4OHC
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BU of 4ohc by Molmil
Crystal structure of orotate phosphoribosyltransferase (OPRTase) from Burkholderia cenocepacia
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Orotate phosphoribosyltransferase, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2014-01-17
Release date:2014-02-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of orotate phosphoribosyltransferase (OPRTase) from Burkholderia cenocepacia
To be Published
4O7V
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BU of 4o7v by Molmil
SAICAR synthetase (Type-2) in complex with ADP and UDP/UMP
Descriptor: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, ...
Authors:Manjunath, K, Jeyakanthan, J, Sekar, K.
Deposit date:2013-12-26
Release date:2014-12-31
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:SAICAR synthetase (Type-2) in complex with ADP and UDP/UMP
To be Published
3R7T
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BU of 3r7t by Molmil
Crystal Structure of Adenylosuccinate Synthetase from Campylobacter jejuni
Descriptor: Adenylosuccinate synthetase, CHLORIDE ION, CITRIC ACID, ...
Authors:Kim, Y, Gu, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-03-23
Release date:2011-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Adenylosuccinate Synthetase from Campylobacter jejuni
To be Published
4PAW
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BU of 4paw by Molmil
Structure of hypothetical protein HP1257.
Descriptor: Orotate phosphoribosyltransferase, PHOSPHATE ION, THIOCYANATE ION, ...
Authors:Battaile, K.P, Lam, R, Lam, K, Romanov, V, Jones, K, Soloveychik, M, Pai, E.F, Chirgadze, N.Y.
Deposit date:2014-04-10
Release date:2015-05-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structure of hypothetical protein HP1257.
To Be Published
3R9R
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BU of 3r9r by Molmil
Structure of a Phosphoribosylaminoimidazole-succinocarboxamide synthase from Mycobacterium abscessus ATCC 19977 / DSM 44196
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-03-25
Release date:2011-04-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.849 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4O7S
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BU of 4o7s by Molmil
SAICAR synthetase (Type-2) in complex with TMP/TDP
Descriptor: ACETATE ION, PHOSPHATE ION, Phosphoribosylaminoimidazole-succinocarboxamide synthase, ...
Authors:Manjunath, K, Jeyakanthan, J, Sekar, K.
Deposit date:2013-12-26
Release date:2014-12-31
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:SAICAR synthetase (Type-2) in complex with TMP/TDP
To be Published
4O86
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BU of 4o86 by Molmil
SAICAR synthetase (Type-2) in complex with ADP and CDP
Descriptor: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, CYTIDINE-5'-DIPHOSPHATE, ...
Authors:Manjunath, K, Jeyakanthan, J, Sekar, K.
Deposit date:2013-12-26
Release date:2014-12-31
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:SAICAR synthetase (Type-2) in complex with ADP and CDP
To be Published

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