PDB: 230764 resultsInfo pagesStatus searchChemie searchBIRD

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8IB4	Respiratory complex CI:CIII2, type IA, Wild type mouse under cold temperature Descriptor: 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... Authors: Shin, Y.-C, Liao, M. Deposit date: 2023-02-09 Release date: 2024-09-18 Last modified: 2024-12-04 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Structural basis of respiratory complex adaptation to cold temperatures. Cell, 187, 2024
8IB9	Respiratory complex CI:CIII2, type IB, Wild type mouse under cold temperature Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL, ... Authors: Shin, Y.-C, Liao, M. Deposit date: 2023-02-10 Release date: 2024-09-18 Last modified: 2024-12-04 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Structural basis of respiratory complex adaptation to cold temperatures. Cell, 187, 2024
5D8L	Human HSF2 DNA Binding Domain in complex with 3-site HSE DNA at 2.1 Angstroms Resolution Descriptor: DNA (5'-D(*GP*GP*TP*TP*CP*TP*AP*GP*AP*AP*TP*AP*TP*TP*CP*AP*C)-3'), DNA (5'-D(P*GP*TP*GP*AP*AP*TP*AP*TP*TP*CP*TP*AP*GP*AP*AP*CP*C)-3'), Heat shock factor protein 2 Authors: Jaeger, A.M, Pemble, C.W, Thiele, D.J. Deposit date: 2015-08-17 Release date: 2016-01-06 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.069 Å) Cite: Structures of HSF2 reveal mechanisms for differential regulation of human heat-shock factors. Nat.Struct.Mol.Biol., 23, 2016
5QCD	Crystal structure of human Cathepsin-S with bound ligand Descriptor: Cathepsin S, SULFATE ION, {(3S)-7-[(2-chloro-5-{5-(methylsulfonyl)-1-[3-(morpholin-4-yl)propyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl}phenyl)ethynyl]-1,2,3,4-tetrahydroisoquinolin-3-yl}(piperidin-1-yl)methanone Authors: Bembenek, S.D, Ameriks, M.K, Mirzadegan, T, Yang, H, Shao, C, Burley, S.K. Deposit date: 2017-08-04 Release date: 2017-12-20 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Crystal structure of human Cathepsin-S with bound ligand To be published
5QCI	Crystal structure of human Cathepsin-S with bound ligand Descriptor: Cathepsin S, GLYCEROL, N-benzyl-1-{5-[(2-chloro-5-{5-(methylsulfonyl)-1-[3-(morpholin-4-yl)propyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl}phenyl)ethynyl]-2-methoxyphenyl}methanamine, ... Authors: Bembenek, S.D, Ameriks, M.K, Mirzadegan, T, Yang, H, Shao, C, Burley, S.K. Deposit date: 2017-08-04 Release date: 2017-12-20 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.179 Å) Cite: Crystal structure of human Cathepsin-S with bound ligand To be published
5QCE	Crystal structure of human Cathepsin-S with bound ligand Descriptor: Cathepsin S, N-benzyl-1-{2-chloro-5-[(2-chloro-5-{5-(methylsulfonyl)-1-[3-(morpholin-4-yl)propyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl}phenyl)ethynyl]phenyl}methanamine Authors: Bembenek, S.D, Ameriks, M.K, Mirzadegan, T, Yang, H, Shao, C, Burley, S.K. Deposit date: 2017-08-04 Release date: 2017-12-20 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.78 Å) Cite: Crystal structure of human Cathepsin-S with bound ligand To be published
5QBU	Crystal structure of human Cathepsin-S with bound ligand Descriptor: 1-[1-(3-{5-(1H-imidazole-5-carbonyl)-3-[4-(trifluoromethyl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-1-yl}propyl)piperidin-4-yl]-3-methyl-1,3-dihydro-2H-benzimidazol-2-one, Cathepsin S Authors: Bembenek, S.D, Ameriks, M.K, Mirzadegan, T, Yang, H, Shao, C, Burley, S.K. Deposit date: 2017-08-04 Release date: 2017-12-20 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.78 Å) Cite: Crystal structure of human Cathepsin-S with bound ligand To be published
5QC5	Crystal structure of human Cathepsin-S with bound ligand Descriptor: 1-[5-{1-[3-(4-tert-butylpiperidin-1-yl)propyl]-5-(methylsulfonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl}-2-(trifluoromethyl)phenyl]-N-[(4-fluorophenyl)methyl]methanamine, Cathepsin S Authors: Bembenek, S.D, Ameriks, M.K, Mirzadegan, T, Yang, H, Shao, C, Burley, S.K. Deposit date: 2017-08-04 Release date: 2017-12-20 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structure of human Cathepsin-S with bound ligand To be published
9MO5	Structure of native murine cardiac thin filament at pCa=5.8 in Ca2+-bound partially activated state (lower strand) Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... Authors: Risi, C.M, Galkin, V.E. Deposit date: 2024-12-25 Release date: 2025-05-28 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (5.3 Å) Cite: The role of the troponin T interactions with actin in regulation of cardiac thin filament revealed by the troponin T pathogenic variant Ile79Asn. J.Mol.Cell.Cardiol., 204, 2025
9MO8	Structure of native murine cardiac thin filament at pCa=5.8 in Ca2+-free state (upper strand) Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... Authors: Risi, C.M, Galkin, V.E. Deposit date: 2024-12-25 Release date: 2025-05-28 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (5.2 Å) Cite: The role of the troponin T interactions with actin in regulation of cardiac thin filament revealed by the troponin T pathogenic variant Ile79Asn. J.Mol.Cell.Cardiol., 204, 2025
9MOB	Structure of native murine cardiac thin filament variant I79N in troponin T at pCa=5.8 in Ca2+-free state (upper strand) Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... Authors: Risi, C.M, Galkin, V.E. Deposit date: 2024-12-25 Release date: 2025-05-28 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (5.5 Å) Cite: The role of the troponin T interactions with actin in regulation of cardiac thin filament revealed by the troponin T pathogenic variant Ile79Asn. J.Mol.Cell.Cardiol., 204, 2025
9QOB	CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX with compound 4 Descriptor: (5-phenyl-[1,3]thiazolo[2,3-c][1,2,4]triazol-3-yl)methanol, 1,2-ETHANEDIOL, Bromodomain-containing protein 4 Authors: Krojer, T, Martinez-Cartro, M, Picaud, S, Filippakopoulos, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Barril, X, von Delft, F. Deposit date: 2025-03-25 Release date: 2025-05-14 Method: X-RAY DIFFRACTION (1.37 Å) Cite: CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX with compound 2 To Be Published
9MOP	Structure of native murine cardiac thin filament variant I79N in troponin T at pCa=5.8 in Ca2+-bound fully activated state (lower strand) Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... Authors: Risi, C.M, Galkin, V.E. Deposit date: 2024-12-26 Release date: 2025-06-04 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (5 Å) Cite: The role of the troponin T interactions with actin in regulation of cardiac thin filament revealed by the troponin T pathogenic variant Ile79Asn. J.Mol.Cell.Cardiol., 204, 2025
9MOL	Structure of native murine cardiac thin filament at pCa=5.8 in Ca2+-free tilted state (upper strand) Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... Authors: Risi, C.M, Galkin, V.E. Deposit date: 2024-12-26 Release date: 2025-06-11 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (5.2 Å) Cite: The role of the troponin T interactions with actin in regulation of cardiac thin filament revealed by the troponin T pathogenic variant Ile79Asn. J.Mol.Cell.Cardiol., 204, 2025
9MOO	Structure of native murine cardiac thin filament variant I79N in troponin T at pCa=5.8 in Ca2+-free state (lower strand) Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... Authors: Risi, C.M, Galkin, V.E. Deposit date: 2024-12-26 Release date: 2025-06-11 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (5.2 Å) Cite: The role of the troponin T interactions with actin in regulation of cardiac thin filament revealed by the troponin T pathogenic variant Ile79Asn. J.Mol.Cell.Cardiol., 204, 2025
9MOM	Structure of native murine cardiac thin filament at pCa=5.8 in Ca2+-bound partially activated state (upper strand) Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... Authors: Risi, C.M, Galkin, V.E. Deposit date: 2024-12-26 Release date: 2025-06-11 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (5.1 Å) Cite: The role of the troponin T interactions with actin in regulation of cardiac thin filament revealed by the troponin T pathogenic variant Ile79Asn. J.Mol.Cell.Cardiol., 204, 2025
9MOA	Structure of native murine cardiac thin filament variant I79N in troponin T at pCa=5.8 in Ca2+-free tilted state (lower strand) Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... Authors: Risi, C.M, Galkin, V.E. Deposit date: 2024-12-25 Release date: 2025-05-28 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (5.4 Å) Cite: The role of the troponin T interactions with actin in regulation of cardiac thin filament revealed by the troponin T pathogenic variant Ile79Asn. J.Mol.Cell.Cardiol., 204, 2025
9MO6	Structure of native murine cardiac thin filament at pCa=5.8 in Ca2+-free tilted state (lower strand) Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... Authors: Risi, C.M, Galkin, V.E. Deposit date: 2024-12-25 Release date: 2025-05-28 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (5.3 Å) Cite: The role of the troponin T interactions with actin in regulation of cardiac thin filament revealed by the troponin T pathogenic variant Ile79Asn. J.Mol.Cell.Cardiol., 204, 2025
9MO9	Structure of native murine cardiac thin filament variant I79N in troponin T at pCa=5.8 in Ca2+-free rotated state (lower strand) Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... Authors: Risi, C.M, Galkin, V.E. Deposit date: 2024-12-25 Release date: 2025-05-28 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (5.6 Å) Cite: The role of the troponin T interactions with actin in regulation of cardiac thin filament revealed by the troponin T pathogenic variant Ile79Asn. J.Mol.Cell.Cardiol., 204, 2025
9MO7	Structure of native murine cardiac thin filament at pCa=5.8 in Ca2+-bound fully activated state (lower strand) Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... Authors: Risi, C.M, Galkin, V.E. Deposit date: 2024-12-25 Release date: 2025-05-28 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (5.2 Å) Cite: The role of the troponin T interactions with actin in regulation of cardiac thin filament revealed by the troponin T pathogenic variant Ile79Asn. J.Mol.Cell.Cardiol., 204, 2025
9MZA	Chemically Hijacked BCL6-TCIP3-p300 Complex Descriptor: 1-{1-[5-({1-[5-chloro-4-({8-methoxy-1-methyl-3-[2-(methylamino)-2-oxoethoxy]-2-oxo-1,2-dihydroquinolin-6-yl}amino)pyrimidin-2-yl]piperidine-4-carbonyl}amino)pentanoyl]piperidin-4-yl}-3-[(6M)-7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl]-N-methyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxamide, B-cell lymphoma 6 protein, Histone acetyltransferase p300 Authors: Hinshaw, S.M, Gray, N.S, Nix, M.N, Gourisankar, S, Martinez, M, Crabtree, G.R. Deposit date: 2025-01-22 Release date: 2025-04-16 Method: X-RAY DIFFRACTION (2.1 Å) Cite: A Bivalent Molecular Glue Linking Lysine Acetyltransferases to Oncogene-induced Cell Death. Biorxiv, 2025
9MOI	Structure of native murine cardiac thin filament at pCa=5.8 in Ca2+-free rotated state (lower strand) Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... Authors: Galkin, V.E, Risi, C.M. Deposit date: 2024-12-26 Release date: 2025-06-04 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (5.4 Å) Cite: The role of the troponin T interactions with actin in regulation of cardiac thin filament revealed by the troponin T pathogenic variant Ile79Asn. J.Mol.Cell.Cardiol., 204, 2025
9MOX	Structure of native murine cardiac thin filament variant I79N in troponin T at pCa=5.8 in Ca2+-bound partially activated state (lower strand) Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... Authors: Risi, C.M, Galkin, V.E. Deposit date: 2024-12-27 Release date: 2025-06-04 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (5.2 Å) Cite: The role of the troponin T interactions with actin in regulation of cardiac thin filament revealed by the troponin T pathogenic variant Ile79Asn. J.Mol.Cell.Cardiol., 204, 2025
9MO4	Structure of native murine cardiac thin filament at pCa=5.8 in Ca2+-free state (lower strand) Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... Authors: Risi, C.M, Galkin, V.E. Deposit date: 2024-12-25 Release date: 2025-05-28 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (5.3 Å) Cite: The role of the troponin T interactions with actin in regulation of cardiac thin filament revealed by the troponin T pathogenic variant Ile79Asn. J.Mol.Cell.Cardiol., 204, 2025
9MOD	Structure of native murine cardiac thin filament variant I79N in troponin T at pCa=5.8 in Ca2+-free tilted state (upper strand) Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... Authors: Risi, C.M, Galkin, V.E. Deposit date: 2024-12-25 Release date: 2025-05-28 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (5.7 Å) Cite: The role of the troponin T interactions with actin in regulation of cardiac thin filament revealed by the troponin T pathogenic variant Ile79Asn. J.Mol.Cell.Cardiol., 204, 2025

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