5VA2
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3J4Q
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5V4S
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![BU of 5v4s by Molmil](/molmil-images/mine/5v4s) | CryoEM Structure of a Prokaryotic Cyclic Nucleotide-Gated Ion Channel | Descriptor: | Transporter, cation channel family / cyclic nucleotide-binding domain multi-domain protein | Authors: | James, Z.M, Borst, A.J, Haitin, Y, Frenz, B, DiMaio, F, Zagotta, W.N, Veesler, D. | Deposit date: | 2017-03-10 | Release date: | 2017-04-12 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | CryoEM structure of a prokaryotic cyclic nucleotide-gated ion channel. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5VA1
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3N4M
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![BU of 3n4m by Molmil](/molmil-images/mine/3n4m) | E. coli RNA polymerase alpha subunit C-terminal domain in complex with CAP and DNA | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, DI(HYDROXYETHYL)ETHER, ... | Authors: | Lara-Gonzalez, S, Birktoft, J.J, Lawson, C.L. | Deposit date: | 2010-05-21 | Release date: | 2011-05-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.987 Å) | Cite: | The RNA Polymerase alpha Subunit Recognizes the DNA Shape of the Upstream Promoter Element. Biochemistry, 59, 2020
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7LV3
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![BU of 7lv3 by Molmil](/molmil-images/mine/7lv3) | Crystal structure of human protein kinase G (PKG) R-C complex in inhibited state | Descriptor: | 1,2-ETHANEDIOL, Isoform Beta of cGMP-dependent protein kinase 1, MANGANESE (II) ION, ... | Authors: | Sharma, R, Lying, Q, Casteel, D, Kim, C. | Deposit date: | 2021-02-23 | Release date: | 2022-08-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | An auto-inhibited state of protein kinase G and implications for selective activation. Elife, 11, 2022
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6V1X
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![BU of 6v1x by Molmil](/molmil-images/mine/6v1x) | Cryo-EM Structure of the Hyperpolarization-Activated Potassium Channel KAT1: Tetramer | Descriptor: | (2S)-1-(nonanoyloxy)-3-(phosphonooxy)propan-2-yl tetradecanoate, (3beta,5beta,14beta,17alpha)-cholestan-3-ol, Potassium channel KAT1 | Authors: | Clark, M.D, Contreras, G.F, Shen, R, Perozo, E. | Deposit date: | 2019-11-21 | Release date: | 2020-06-03 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Electromechanical coupling in the hyperpolarization-activated K + channel KAT1. Nature, 583, 2020
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6UQF
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![BU of 6uqf by Molmil](/molmil-images/mine/6uqf) | Human HCN1 channel in a hyperpolarized conformation | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, MERCURY (II) ION, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | Authors: | Lee, C.-H, MacKinnon, R. | Deposit date: | 2019-10-19 | Release date: | 2019-12-11 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Voltage Sensor Movements during Hyperpolarization in the HCN Channel. Cell, 179, 2019
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6UQG
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![BU of 6uqg by Molmil](/molmil-images/mine/6uqg) | Human HCN1 channel Y289D mutant | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | Authors: | Lee, C.-H, MacKinnon, R. | Deposit date: | 2019-10-19 | Release date: | 2019-12-11 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Voltage Sensor Movements during Hyperpolarization in the HCN Channel. Cell, 179, 2019
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7NP3
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![BU of 7np3 by Molmil](/molmil-images/mine/7np3) | cAMP-free rabbit HCN4 stabilized in LMNG-CHS detergent mixture | Descriptor: | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4,Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | Authors: | Giese, H.M, Chaves-Sanjuan, A, Saponaro, A, Clarke, O, Bolognesi, M, Mancia, F, Hendrickson, W.A, Thiel, G, Santoro, B, Moroni, A. | Deposit date: | 2021-02-26 | Release date: | 2021-08-11 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Gating movements and ion permeation in HCN4 pacemaker channels. Mol.Cell, 81, 2021
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1LB2
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![BU of 1lb2 by Molmil](/molmil-images/mine/1lb2) | Structure of the E. coli alpha C-terminal domain of RNA polymerase in complex with CAP and DNA | Descriptor: | 5'-D(*CP*TP*AP*GP*AP*TP*CP*AP*CP*AP*TP*TP*TP*TP*AP*GP*GP*AP*AP*AP*AP*AP*AP*G)-3', 5'-D(*CP*TP*TP*TP*TP*TP*TP*CP*CP*TP*AP*AP*AP*AP*TP*GP*TP*GP*AP*T)-3', ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ... | Authors: | Benoff, B, Yang, H, Lawson, C.L, Parkinson, G, Liu, J, Blatter, E, Ebright, Y.W, Berman, H.M, Ebright, R.H. | Deposit date: | 2002-04-01 | Release date: | 2002-09-06 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural basis of transcription activation: the CAP-alpha CTD-DNA complex. Science, 297, 2002
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4AVB
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![BU of 4avb by Molmil](/molmil-images/mine/4avb) | Crystal structure of protein lysine acetyltransferase Rv0998 in complex with acetyl CoA and cAMP | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, ACETYL COENZYME *A, ... | Authors: | Lee, H.J, Lang, P.T, Fortune, S.M, Sassetti, C.M, Alber, T. | Deposit date: | 2012-05-24 | Release date: | 2012-07-11 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Cyclic AMP Regulation of Protein Lysine Acetylation in Mycobacterium Tuberculosis. Nat.Struct.Mol.Biol., 19, 2012
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4AVC
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![BU of 4avc by Molmil](/molmil-images/mine/4avc) | Crystal structure of protein lysine acetyltransferase Rv0998 in complex with acetyl CoA and cAMP | Descriptor: | 1,2-ETHANEDIOL, ACETYL COENZYME *A, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ... | Authors: | Lee, H.J, Lang, P.T, Fortune, S.M, Sassetti, C.M, Alber, T. | Deposit date: | 2012-05-24 | Release date: | 2012-07-11 | Last modified: | 2012-08-22 | Method: | X-RAY DIFFRACTION (2.806 Å) | Cite: | Cyclic AMP Regulation of Protein Lysine Acetylation in Mycobacterium Tuberculosis. Nat.Struct.Mol.Biol., 19, 2012
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4AVA
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![BU of 4ava by Molmil](/molmil-images/mine/4ava) | Crystal structure of protein lysine acetyltransferase Rv0998 from Mycobacterium tuberculosis | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, ACETYL COENZYME *A, ... | Authors: | Lee, H.J, Lang, P.T, Fortune, S.M, Sassetti, C.M, Alber, T. | Deposit date: | 2012-05-24 | Release date: | 2012-07-11 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.698 Å) | Cite: | Cyclic AMP Regulation of Protein Lysine Acetylation in Mycobacterium Tuberculosis. Nat.Struct.Mol.Biol., 19, 2012
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4BH9
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4BHP
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7N16
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![BU of 7n16 by Molmil](/molmil-images/mine/7n16) | Structure of TAX-4_R421W apo closed state | Descriptor: | 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cyclic nucleotide-gated cation channel, SODIUM ION | Authors: | Zheng, X, Li, H, Hu, Z, Su, D, Yang, J. | Deposit date: | 2021-05-27 | Release date: | 2022-03-16 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural and functional characterization of an achromatopsia-associated mutation in a phototransduction channel. Commun Biol, 5, 2022
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7N17
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![BU of 7n17 by Molmil](/molmil-images/mine/7n17) | Structure of TAX-4_R421W apo open state | Descriptor: | 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cyclic nucleotide-gated cation channel | Authors: | Zheng, X, Li, H, Hu, Z, Su, D, Yang, J. | Deposit date: | 2021-05-27 | Release date: | 2022-03-16 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural and functional characterization of an achromatopsia-associated mutation in a phototransduction channel. Commun Biol, 5, 2022
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7N15
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![BU of 7n15 by Molmil](/molmil-images/mine/7n15) | Structure of TAX-4_R421W w/cGMP open state | Descriptor: | 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CYCLIC GUANOSINE MONOPHOSPHATE, ... | Authors: | Zheng, X, Li, H, Hu, Z, Su, D, Yang, J. | Deposit date: | 2021-05-27 | Release date: | 2022-03-16 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural and functional characterization of an achromatopsia-associated mutation in a phototransduction channel. Commun Biol, 5, 2022
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6VXZ
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![BU of 6vxz by Molmil](/molmil-images/mine/6vxz) | SthK P300A cyclic nucleotide-gated potassium channel in the closed state, in complex with cAMP | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SthK | Authors: | Schmidpeter, P.A.M, Rheinberger, J, Nimigean, C.M. | Deposit date: | 2020-02-25 | Release date: | 2020-11-11 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | Prolyl isomerization controls activation kinetics of a cyclic nucleotide-gated ion channel. Nat Commun, 11, 2020
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7NMN
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![BU of 7nmn by Molmil](/molmil-images/mine/7nmn) | Rabbit HCN4 stabilised in amphipol A8-35 | Descriptor: | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4,Rabbit HCN4 | Authors: | Chaves-Sanjuan, A. | Deposit date: | 2021-02-23 | Release date: | 2021-06-30 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Gating movements and ion permeation in HCN4 pacemaker channels. Mol.Cell, 81, 2021
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6VY0
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7NP4
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![BU of 7np4 by Molmil](/molmil-images/mine/7np4) | cAMP-bound rabbit HCN4 stabilized in LMNG-CHS detergent mixture | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4,Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | Authors: | Giese, H, Chaves-Sanjuan, A, Saponaro, A, Clarke, O, Bolognesi, M, Mancia, F, Hendrickson, W.A, Thiel, G, Santoro, B, Moroni, A. | Deposit date: | 2021-02-26 | Release date: | 2021-08-11 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Gating movements and ion permeation in HCN4 pacemaker channels. Mol.Cell, 81, 2021
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1O3R
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![BU of 1o3r by Molmil](/molmil-images/mine/1o3r) | PROTEIN-DNA RECOGNITION AND DNA DEFORMATION REVEALED IN CRYSTAL STRUCTURES OF CAP-DNA COMPLEXES | Descriptor: | 5'-D(*AP*AP*AP*AP*AP*TP*GP*CP*GP*AP*T)-3', 5'-D(*CP*TP*AP*GP*AP*TP*CP*GP*CP*AP*TP*TP*TP*TP*T)-3', ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ... | Authors: | Chen, S, Vojtechovsky, J, Parkinson, G.N, Ebright, R.H, Berman, H.M. | Deposit date: | 2003-03-18 | Release date: | 2003-04-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Indirect Readout of DNA Sequence at the Primary-kink Site in the CAP-DNA Complex: DNA Binding Specificity Based on Energetics of DNA Kinking J.Mol.Biol., 314, 2001
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1O3Q
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![BU of 1o3q by Molmil](/molmil-images/mine/1o3q) | PROTEIN-DNA RECOGNITION AND DNA DEFORMATION REVEALED IN CRYSTAL STRUCTURES OF CAP-DNA COMPLEXES | Descriptor: | 5'-D(*AP*AP*AP*AP*AP*TP*GP*TP*GP*AP*T)-3', 5'-D(*CP*TP*AP*GP*AP*TP*CP*AP*CP*AP*TP*TP*TP*TP*T)-3', ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ... | Authors: | Chen, S, Vojtechovsky, J, Parkinson, G.N, Ebright, R.H, Berman, H.M. | Deposit date: | 2003-03-18 | Release date: | 2003-04-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Indirect Readout of DNA Sequence at the Primary-kink Site in the CAP-DNA Complex: DNA Binding Specificity Based on Energetics of DNA Kinking J.Mol.Biol., 314, 2001
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