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7FD4
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BU of 7fd4 by Molmil
A complete three-dimensional structure of the Lon protease translocating a protein substrate (conformation 1)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Alpha-S1-casein, Lon protease, ...
Authors:Li, S, Hsieh, K, Kuo, C, Lee, S, Pintilie, G, Zhang, K, Chang, C.
Deposit date:2021-07-16
Release date:2021-11-03
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Complete three-dimensional structures of the Lon protease translocating a protein substrate.
Sci Adv, 7, 2021
7FD5
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BU of 7fd5 by Molmil
A complete three-dimensional structure of the Lon protease translocating a protein substrate (conformation 2)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Alpha-S1-casein, Lon protease, ...
Authors:Li, S, Hsieh, K, Kuo, C, Lee, S, Pintilie, G, Zhang, K, Chang, C.
Deposit date:2021-07-16
Release date:2021-11-03
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Complete three-dimensional structures of the Lon protease translocating a protein substrate.
Sci Adv, 7, 2021
7FID
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BU of 7fid by Molmil
Processive cleavage of substrate at individual proteolytic active sites of the Lon proteasecomplex (conformation 1)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Li, S, Hsieh, K, Kuo, C, Su, S, Huang, K, Zhang, K, Chang, C.I.
Deposit date:2021-07-31
Release date:2021-11-24
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.44 Å)
Cite:Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex.
Sci Adv, 7, 2021
7FIZ
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BU of 7fiz by Molmil
Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex (conformation 3)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Li, S, Hsieh, K, Kuo, C, Su, S, Huang, K, Zhang, K, Chang, C.I.
Deposit date:2021-08-01
Release date:2021-11-24
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex.
Sci Adv, 7, 2021
7FIE
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BU of 7fie by Molmil
Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex (conformation 2)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Li, S, Hsieh, K, Kuo, C, Su, S, Huang, K, Zhang, K, Chang, C.I.
Deposit date:2021-07-31
Release date:2021-11-24
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.36 Å)
Cite:Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex.
Sci Adv, 7, 2021
8R0E
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BU of 8r0e by Molmil
p97 (VCP) mutant - F266A
Descriptor: Transitional endoplasmic reticulum ATPase
Authors:Arie, M, Matzov, D, Karmona, R, Szenkier, N, Stanhill, A, Navon, A.
Deposit date:2023-10-31
Release date:2024-05-29
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:p97 (VCP) mutant - F266A
To Be Published
5WYJ
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BU of 5wyj by Molmil
Cryo-EM structure of the 90S small subunit pre-ribosome (Dhr1-depleted, Enp1-TAP, state 1)
Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S ribosomal RNA, 40S ribosomal protein S1-A, ...
Authors:Ye, K, Zhu, X, Sun, Q.
Deposit date:2017-01-13
Release date:2017-03-29
Last modified:2019-10-09
Method:ELECTRON MICROSCOPY (8.7 Å)
Cite:Molecular architecture of the 90S small subunit pre-ribosome.
Elife, 6, 2017
5WLC
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BU of 5wlc by Molmil
The complete structure of the small subunit processome
Descriptor: 18S pre-rRNA, 5' ETS, Bms1, ...
Authors:Barandun, J, Chaker-Margot, M, Hunziker, M, Klinge, S.
Deposit date:2017-07-26
Release date:2017-09-27
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:The complete structure of the small-subunit processome.
Nat. Struct. Mol. Biol., 24, 2017
5WVK
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BU of 5wvk by Molmil
Yeast proteasome-ADP-AlFx
Descriptor: 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ...
Authors:Ding, Z, Cong, Y.
Deposit date:2016-12-25
Release date:2017-03-22
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:High-resolution cryo-EM structure of the proteasome in complex with ADP-AlFx
Cell Res., 27, 2017
7CTG
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BU of 7ctg by Molmil
Human Origin Recognition Complex, ORC1-5 State I
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Origin recognition complex subunit 1, Origin recognition complex subunit 2, ...
Authors:Cheng, J, Li, N, Wang, X, Hu, J, Zhai, Y, Gao, N.
Deposit date:2020-08-18
Release date:2021-01-06
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Structural insight into the assembly and conformational activation of human origin recognition complex.
Cell Discov, 6, 2020
8OVF
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BU of 8ovf by Molmil
Human Mitochondrial Lon Y186F Mutant ADP Bound
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial
Authors:Kereiche, S, Bauer, J.A, Matyas, P, Novacek, J, Kutejova, E.
Deposit date:2023-04-26
Release date:2024-05-08
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (7.23 Å)
Cite:Polyphosphate and tyrosine phosphorylation in the N-terminal domain of the human mitochondrial Lon protease disrupts its functions.
Sci Rep, 14, 2024
8OVG
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BU of 8ovg by Molmil
Human Mitochondrial Lon Y186E Mutant ADP Bound
Descriptor: Lon protease homolog, mitochondrial
Authors:Kereiche, S, Bauer, J.A, Matyas, P, Novacek, J, Kutejova, E.
Deposit date:2023-04-26
Release date:2024-05-08
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (8.47 Å)
Cite:Polyphosphate and tyrosine phosphorylation in the N-terminal domain of the human mitochondrial Lon protease disrupts its functions.
Sci Rep, 14, 2024
8RSC
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BU of 8rsc by Molmil
p97 (VCP) mutant - F539A
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase
Authors:Arie, M, Matzov, D, Karmona, R, Szenkier, N, Stanhill, A, Navon, A.
Deposit date:2024-01-24
Release date:2024-05-29
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:p97 (VCP) mutant - F539A
To Be Published
5XMK
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BU of 5xmk by Molmil
Cryo-EM structure of the ATP-bound Vps4 mutant-E233Q complex with Vta1 (masked)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Vacuolar protein sorting-associated protein 4, Vacuolar protein sorting-associated protein VTA1
Authors:Sun, S, Li, L, Yang, F, Wang, X, Fan, F, Li, X, Wang, H, Sui, S.
Deposit date:2017-05-15
Release date:2017-08-09
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.18 Å)
Cite:Cryo-EM structures of the ATP-bound Vps4(E233Q) hexamer and its complex with Vta1 at near-atomic resolution
Nat Commun, 8, 2017
8T14
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BU of 8t14 by Molmil
ADP-bound Bcs1 (C7 symmetrized)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Mitochondrial chaperone BCS1
Authors:Zhan, J, Xia, D.
Deposit date:2023-06-01
Release date:2024-06-05
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate.
Nat Commun, 15, 2024
8TBY
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BU of 8tby by Molmil
Apo Bcs1, unsymmetrized
Descriptor: Mitochondrial chaperone BCS1
Authors:Zhan, J, Xia, D.
Deposit date:2023-06-29
Release date:2024-06-05
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate.
Nat Commun, 15, 2024
8T5U
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BU of 8t5u by Molmil
ATP-1 state of Bcs1 (C7 symmetrized)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1
Authors:Zhan, J, Xia, D.
Deposit date:2023-06-14
Release date:2024-06-05
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate.
Nat Commun, 15, 2024
8T7U
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BU of 8t7u by Molmil
ADP-bound Bcs1 (unsymmetrized)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Mitochondrial chaperone BCS1
Authors:Zhan, J, Xia, D.
Deposit date:2023-06-21
Release date:2024-06-05
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate.
Nat Commun, 15, 2024
8D6Y
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BU of 8d6y by Molmil
Structure of the Mycobacterium tuberculosis 20S proteasome bound to the ADP-bound Mpa ATPase
Descriptor: AAA ATPase forming ring-shaped complexes, Proteasome subunit alpha, Proteasome subunit beta, ...
Authors:Xiao, X, Li, H.
Deposit date:2022-06-06
Release date:2022-08-03
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (10 Å)
Cite:The beta-Grasp Domain of Proteasomal ATPase Mpa Makes Critical Contacts with the Mycobacterium tuberculosis 20S Core Particle to Facilitate Degradation.
Msphere, 7, 2022
8CVT
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BU of 8cvt by Molmil
Human 19S-20S proteasome, state SD2
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ...
Authors:Zhao, J.
Deposit date:2022-05-18
Release date:2022-11-02
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins.
Proc.Natl.Acad.Sci.USA, 119, 2022
8D6X
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BU of 8d6x by Molmil
Structure of the Mycobacterium tuberculosis 20S proteasome bound to the ATP-bound Mpa ATPase
Descriptor: AAA ATPase forming ring-shaped complexes, Proteasome subunit alpha, Proteasome subunit beta, ...
Authors:Xiao, X, Li, H.
Deposit date:2022-06-06
Release date:2022-08-03
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:The beta-Grasp Domain of Proteasomal ATPase Mpa Makes Critical Contacts with the Mycobacterium tuberculosis 20S Core Particle to Facilitate Degradation.
Msphere, 7, 2022
8DAW
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BU of 8daw by Molmil
Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex bound to three ubiquitin moieties and one unfolded ubiquitin in presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP, state 2 (uD)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ...
Authors:Lee, H.G, Lima, C.D.
Deposit date:2022-06-14
Release date:2022-11-30
Last modified:2023-01-11
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:SUMO enhances unfolding of SUMO-polyubiquitin-modified substrates by the Ufd1/Npl4/Cdc48 complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DAU
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BU of 8dau by Molmil
Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex bound to two folded ubiquitin moieties and one unfolded ubiquitin in presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP, state 1 (uA)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ...
Authors:Lee, H.G, Lima, C.D.
Deposit date:2022-06-14
Release date:2022-11-30
Last modified:2023-01-11
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:SUMO enhances unfolding of SUMO-polyubiquitin-modified substrates by the Ufd1/Npl4/Cdc48 complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DAR
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BU of 8dar by Molmil
Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex unbound but in the presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ...
Authors:Lee, H.G, Lima, C.D.
Deposit date:2022-06-14
Release date:2022-11-30
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3 Å)
Cite:SUMO enhances unfolding of SUMO-polyubiquitin-modified substrates by the Ufd1/Npl4/Cdc48 complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DAT
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BU of 8dat by Molmil
Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex bound to three ubiquitin moieties in presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP, state 1 (intB)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ...
Authors:Lee, H.G, Lima, C.D.
Deposit date:2022-06-14
Release date:2022-11-30
Last modified:2023-01-11
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:SUMO enhances unfolding of SUMO-polyubiquitin-modified substrates by the Ufd1/Npl4/Cdc48 complex.
Proc.Natl.Acad.Sci.USA, 120, 2023

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