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PDB: 127 results
4XFY
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BU of 4xfy by Molmil
Structure of the native full-length dehydrated HIV-1 capsid protein
Descriptor: CHLORIDE ION, HIV-1 capsid protein, PENTAETHYLENE GLYCOL
Authors:Gres, A.T, Kirby, K.A, Sarafianos, S.G.
Deposit date:2014-12-29
Release date:2015-06-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:STRUCTURAL VIROLOGY. X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability.
Science, 349, 2015
8CKV
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BU of 8ckv by Molmil
HIV-1 mature capsid hexamer from CA-IP6 CLPs
Descriptor: Gag polyprotein
Authors:Stacey, J.C.V, Briggs, J.A.G.
Deposit date:2023-02-16
Release date:2023-04-26
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding.
Proc.Natl.Acad.Sci.USA, 120, 2023
7MN0
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BU of 7mn0 by Molmil
N74D mutant of the HIV-1 capsid protein
Descriptor: IODIDE ION, capsid protein
Authors:Gres, A.T, Kirby, K.A, Sarafianos, S.G.
Deposit date:2021-04-30
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:TRIM5alpha Restriction of HIV-1-N74D Viruses in Lymphocytes Is Caused by a Loss of Cyclophilin A Protection.
Viruses, 14, 2022
6OBH
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BU of 6obh by Molmil
Structure of HIV-1 CA 1/2-hexamer
Descriptor: CA, SODIUM ION
Authors:Summers, B.J, Xiong, Y.
Deposit date:2019-03-20
Release date:2019-08-28
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Modular HIV-1 Capsid Assemblies Reveal Diverse Host-Capsid Recognition Mechanisms.
Cell Host Microbe, 26, 2019
8CKX
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BU of 8ckx by Molmil
HIV-1 mature capsid hexamer next to pentamer (type I) from CA-IP6 CLPs
Descriptor: Gag polyprotein
Authors:Stacey, J.C.V, Briggs, J.A.G.
Deposit date:2023-02-16
Release date:2023-04-26
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding.
Proc.Natl.Acad.Sci.USA, 120, 2023
4U0D
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BU of 4u0d by Molmil
Hexameric HIV-1 CA in complex with Nup153 peptide, P212121 crystal form
Descriptor: CHLORIDE ION, Gag polyprotein, Nuclear pore complex protein Nup153
Authors:Price, A.J, Jacques, D.A, James, L.C.
Deposit date:2014-07-11
Release date:2014-11-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly.
Plos Pathog., 10, 2014
8CKZ
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BU of 8ckz by Molmil
HIV-1 mature capsid pentamer from CA-IP6 CLPs bound to Nup153 peptide
Descriptor: Gag polyprotein
Authors:Stacey, J.C.V, Briggs, J.A.G.
Deposit date:2023-02-16
Release date:2023-04-26
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EET
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BU of 8eet by Molmil
T=1 particle HIV-1 CA M66A
Descriptor: Gag polyprotein, INOSITOL HEXAKISPHOSPHATE
Authors:Pornillos, O, Ganser-Pornillos, B.K, Schirra, R.T.
Deposit date:2022-09-07
Release date:2023-02-15
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:A molecular switch modulates assembly and host factor binding of the HIV-1 capsid.
Nat.Struct.Mol.Biol., 30, 2023
5HGL
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BU of 5hgl by Molmil
Hexameric HIV-1 CA, open conformation
Descriptor: CHLORIDE ION, Capsid protein P24, N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE
Authors:Price, A.J, Jacques, D.A, James, L.C.
Deposit date:2016-01-08
Release date:2016-08-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis.
Nature, 536, 2016
8G6O
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BU of 8g6o by Molmil
HIV-1 capsid lattice bound to IP6 and Lenacapavir
Descriptor: Capsid protein
Authors:Highland, C.M, Dick, R.A.
Deposit date:2023-02-15
Release date:2023-05-03
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM.
Proc.Natl.Acad.Sci.USA, 120, 2023
8G6M
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BU of 8g6m by Molmil
HIV-1 CA lattice bound to IP6, pH 7.4
Descriptor: Capsid protein
Authors:Highland, C.M, Dick, R.A.
Deposit date:2023-02-15
Release date:2023-05-03
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM.
Proc.Natl.Acad.Sci.USA, 120, 2023
8CL0
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BU of 8cl0 by Molmil
HIV-1 mature capsid hexamer next to pentamer (type I) from CA-IP6 CLPs bound to Nup153 peptide.
Descriptor: Gag polyprotein, Nuclear pore complex protein Nup153
Authors:Stacey, J.C.V, Briggs, J.A.G.
Deposit date:2023-02-16
Release date:2023-04-26
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding.
Proc.Natl.Acad.Sci.USA, 120, 2023
8CKW
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BU of 8ckw by Molmil
HIV-1 mature capsid pentamer from CA-IP6 CLPs
Descriptor: Gag polyprotein
Authors:Stacey, J.C.V, Briggs, J.A.G.
Deposit date:2023-02-16
Release date:2023-04-26
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding.
Proc.Natl.Acad.Sci.USA, 120, 2023
8CL3
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BU of 8cl3 by Molmil
HIV-1 mature capsid hexamer from CA-IP6 CLPs, bound to Sec24C peptide.
Descriptor: Gag polyprotein, Protein transport protein Sec24C
Authors:Stacey, J.C.V, Briggs, J.A.G.
Deposit date:2023-02-16
Release date:2023-04-26
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding.
Proc.Natl.Acad.Sci.USA, 120, 2023
8CL4
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BU of 8cl4 by Molmil
HIV-1 mature capsid pentamer from CA-IP6 CLPs bound to Sec24C peptide
Descriptor: Gag polyprotein
Authors:Stacey, J.C.V, Briggs, J.A.G.
Deposit date:2023-02-16
Release date:2023-04-26
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding.
Proc.Natl.Acad.Sci.USA, 120, 2023
7T13
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BU of 7t13 by Molmil
Hexameric HIV-1 (M-group) CA Q50Y mutant
Descriptor: Capsid protein p24
Authors:Jacques, D.A, James, L.C.
Deposit date:2021-12-01
Release date:2022-10-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Evasion of cGAS and TRIM5 defines pandemic HIV.
Nat Microbiol, 7, 2022
7N9U
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BU of 7n9u by Molmil
CA-targeting nanobody is a tool for studying HIV-1 capsid lattice interactions
Descriptor: Capsid protein, Nanobody
Authors:Gerber, E.E, Digianantonio, K.M, Tripler, T.N, Smaga, S.S, Summers, B.J, Xiong, Y.
Deposit date:2021-06-18
Release date:2022-06-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:CA-targeting nanobody is a tool for studying HIV-1 capsid lattice interactions
To Be Published
6MQA
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BU of 6mqa by Molmil
Structure of HIV-1 CA P207S
Descriptor: CHLORIDE ION, Capsid protein, IODIDE ION
Authors:Smaga, S.S, Xiong, Y.
Deposit date:2018-10-09
Release date:2019-06-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.199 Å)
Cite:MxB Restricts HIV-1 by Targeting the Tri-hexamer Interface of the Viral Capsid.
Structure, 27, 2019
6MQO
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BU of 6mqo by Molmil
Structure of HIV-1 CA G208R
Descriptor: Capsid protein, IODIDE ION
Authors:Smaga, S.S, Xiong, Y.
Deposit date:2018-10-10
Release date:2019-06-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:MxB Restricts HIV-1 by Targeting the Tri-hexamer Interface of the Viral Capsid.
Structure, 27, 2019
6MQP
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BU of 6mqp by Molmil
Structure of HIV-1 CA T210K
Descriptor: CHLORIDE ION, Capsid protein, IODIDE ION
Authors:Smaga, S.S, Xiong, Y.
Deposit date:2018-10-10
Release date:2019-06-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.296 Å)
Cite:MxB Restricts HIV-1 by Targeting the Tri-hexamer Interface of the Viral Capsid.
Structure, 27, 2019
8GDV
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BU of 8gdv by Molmil
Structure of M66I mutant of disulfide stabilized HIV-1 CA hexamer in complex with CPSF6 peptide and IP6
Descriptor: Cleavage and polyadenylation specificity factor subunit 6, Gag polyprotein, INOSITOL HEXAKISPHOSPHATE
Authors:Briganti, L, Schope, L, Kvaratskhelia, M.
Deposit date:2023-03-06
Release date:2024-03-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of M66I mutant of disulfide stabilized HIV-1 CA hexamer in complex with CPSF6 peptide and IP6
To Be Published
8TY6
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BU of 8ty6 by Molmil
Disulfide-stabilized HIV-1 CA hexamer in complex with PQBP1 Nt
Descriptor: Capsid protein p24
Authors:Piacentini, J, Pornillos, O, Ganser-Pornillos, B.K.
Deposit date:2023-08-24
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Molecular Determinants of PQBP1 Binding to the HIV-1 Capsid Lattice.
J.Mol.Biol., 436, 2024
8G6L
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BU of 8g6l by Molmil
HIV-1 capsid lattice bound to IP6, pH 6.2
Descriptor: Capsid protein
Authors:Highland, C.M, Dick, R.A.
Deposit date:2023-02-15
Release date:2023-05-03
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM.
Proc.Natl.Acad.Sci.USA, 120, 2023
7E1I
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BU of 7e1i by Molmil
Crystal structure of Pr55Gag-matrix domain in complex with IP6 at ambient temperature in space group P1
Descriptor: Capsid protein p24, INOSITOL HEXAKISPHOSPHATE
Authors:DeMirci, H, Destan, E.
Deposit date:2021-02-01
Release date:2021-08-04
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.301 Å)
Cite:Crystal structure of Pr55Gag-matrix domain in complex with IP6 at ambient temperature in space group P1
To Be Published
7RJ4
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BU of 7rj4 by Molmil
Co-crystal structure of lenacapavir bound to N74D mutant of disulfide stabilized HIV-1 CA hexamer
Descriptor: CAPSID PROTEIN P24, CHLORIDE ION, IODIDE ION, ...
Authors:Bester, S.M, Kvaratskhelia, M.
Deposit date:2021-07-20
Release date:2022-07-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Structural and Mechanistic Bases of Viral Resistance to HIV-1 Capsid Inhibitor Lenacapavir.
Mbio, 13, 2022

222415

건을2024-07-10부터공개중

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