6DNC
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![BU of 6dnc by Molmil](/molmil-images/mine/6dnc) | E.coli RF1 bound to E.coli 70S ribosome in response to UAU sense A-site codon | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Svidritskiy, E, Demo, G, Korostelev, A.A. | Deposit date: | 2018-06-06 | Release date: | 2018-07-04 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Mechanism of premature translation termination on a sense codon. J. Biol. Chem., 293, 2018
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4V4R
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![BU of 4v4r by Molmil](/molmil-images/mine/4v4r) | Crystal structure of the whole ribosomal complex. | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Petry, S, Brodersen, D.E, Murphy IV, F.V, Dunham, C.M, Selmer, M, Tarry, M.J, Kelley, A.C, Ramakrishnan, V. | Deposit date: | 2005-09-30 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (5.9 Å) | Cite: | Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon. Cell(Cambridge,Mass.), 123, 2005
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7NQH
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![BU of 7nqh by Molmil](/molmil-images/mine/7nqh) | 55S mammalian mitochondrial ribosome with mtRF1a and P-site tRNAMet | Descriptor: | 12S rRNA, 16S rRNA, 28S ribosomal protein S16, ... | Authors: | Kummer, E, Schubert, K, Ban, N. | Deposit date: | 2021-03-01 | Release date: | 2021-05-05 | Last modified: | 2021-12-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of translation termination, rescue, and recycling in mammalian mitochondria. Mol.Cell, 81, 2021
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5O2R
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![BU of 5o2r by Molmil](/molmil-images/mine/5o2r) | Cryo-EM structure of the proline-rich antimicrobial peptide Api137 bound to the terminating ribosome | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Graf, M, Berninghausen, O, Beckmann, R, Wilson, D.N. | Deposit date: | 2017-05-22 | Release date: | 2017-07-26 | Last modified: | 2019-02-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome. Nat. Struct. Mol. Biol., 24, 2017
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2IHR
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![BU of 2ihr by Molmil](/molmil-images/mine/2ihr) | RF2 of Thermus thermophilus | Descriptor: | Peptide chain release factor 2 | Authors: | Dobbek, H, Voertler, C.S, Sprinzl, M. | Deposit date: | 2006-09-27 | Release date: | 2007-02-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Release factors 2 from Escherichia coli and Thermus thermophilus: structural, spectroscopic and microcalorimetric studies. Nucleic Acids Res., 35, 2007
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6SZS
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![BU of 6szs by Molmil](/molmil-images/mine/6szs) | Release factor-dependent ribosome rescue by BrfA in the Gram-positive bacterium Bacillus subtilis | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Muller, C, Beckert, B, Wilson, D.N. | Deposit date: | 2019-10-02 | Release date: | 2019-12-04 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | Release factor-dependent ribosome rescue by BrfA in the Gram-positive bacterium Bacillus subtilis. Nat Commun, 10, 2019
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1GQE
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![BU of 1gqe by Molmil](/molmil-images/mine/1gqe) | |
1RQ0
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![BU of 1rq0 by Molmil](/molmil-images/mine/1rq0) | Crystal structure of peptide releasing factor 1 | Descriptor: | Peptide chain release factor 1 | Authors: | Shin, D.H, Brandsen, J, Jancarik, J, Yokota, H, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC) | Deposit date: | 2003-12-03 | Release date: | 2004-08-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural analyses of peptide release factor 1 from Thermotoga maritima reveal domain flexibility required for its interaction with the ribosome. J.Mol.Biol., 341, 2004
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8AKN
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![BU of 8akn by Molmil](/molmil-images/mine/8akn) | Cryo-EM structure of the proline-rich antimicrobial peptide drosocin bound to the terminating ribosome | Descriptor: | 16S ribosomal RNA, 2-acetamido-2-deoxy-alpha-D-galactopyranose, 23S ribosomal RNA, ... | Authors: | Koller, T.O, Morici, M, Wilson, D.N. | Deposit date: | 2022-07-30 | Release date: | 2023-03-08 | Last modified: | 2023-09-06 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Structural basis for translation inhibition by the glycosylated drosocin peptide. Nat.Chem.Biol., 19, 2023
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5H5U
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![BU of 5h5u by Molmil](/molmil-images/mine/5h5u) | Mechanistic insights into the alternative translation termination by ArfA and RF2 | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Ma, C, Kurita, D, Li, N, Chen, Y, Himeno, H, Gao, N. | Deposit date: | 2016-11-09 | Release date: | 2017-01-25 | Last modified: | 2018-10-24 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Mechanistic insights into the alternative translation termination by ArfA and RF2 Nature, 541, 2017
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7M5D
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![BU of 7m5d by Molmil](/molmil-images/mine/7m5d) | |
1ZBT
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![BU of 1zbt by Molmil](/molmil-images/mine/1zbt) | |
4V4S
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![BU of 4v4s by Molmil](/molmil-images/mine/4v4s) | Crystal structure of the whole ribosomal complex. | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Petry, S, Brodersen, D.E, Murphy IV, F.V, Dunham, C.M, Selmer, M, Tarry, M.J, Kelley, A.C, Ramakrishnan, V. | Deposit date: | 2005-10-12 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (6.76 Å) | Cite: | Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon. Cell(Cambridge,Mass.), 123, 2005
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4V9N
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![BU of 4v9n by Molmil](/molmil-images/mine/4v9n) | Crystal structure of the 70S ribosome bound with the Q253P mutant of release factor RF2. | Descriptor: | 16S rRNA (1504-MER), 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Santos, N, Zhu, J, Donohue, J.P, Korostelev, A.A, Noller, H.F. | Deposit date: | 2013-04-26 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Crystal Structure of the 70S Ribosome Bound with the Q253P Mutant Form of Release Factor RF2. Structure, 21, 2013
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5CZP
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![BU of 5czp by Molmil](/molmil-images/mine/5czp) | 70S termination complex containing E. coli RF2 | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Hoffer, E.D, Dunham, C.M. | Deposit date: | 2015-07-31 | Release date: | 2016-10-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.29995918 Å) | Cite: | Uniformity of Peptide Release Is Maintained by Methylation of Release Factors. Cell Rep, 17, 2016
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7O1C
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![BU of 7o1c by Molmil](/molmil-images/mine/7o1c) | Cryo-EM structure of an Escherichia coli TnaC(R23F)-ribosome-RF2 complex stalled in response to L-tryptophan | Descriptor: | 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | Authors: | van der Stel, A.X, Gordon, E.R, Sengupta, A, Martinez, A.K, Klepacki, D, Perry, T.N, Herrero del Valle, A, Vazquez-Laslop, N, Sachs, M.S, Cruz-Vera, L.R, Innis, C.A. | Deposit date: | 2021-03-29 | Release date: | 2021-09-01 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural basis for the tryptophan sensitivity of TnaC-mediated ribosome stalling. Nat Commun, 12, 2021
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7OJ0
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![BU of 7oj0 by Molmil](/molmil-images/mine/7oj0) | Cryo-EM structure of 70S ribosome stalled with TnaC peptide and RF2 | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Su, T, Kudva, R, Becker, T, Berninghausen, O, Heijne, G, Cheng, J, Beckmann, R. | Deposit date: | 2021-05-13 | Release date: | 2021-09-15 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of l-tryptophan-dependent inhibition of release factor 2 by the TnaC arrest peptide. Nucleic Acids Res., 49, 2021
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5DFE
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![BU of 5dfe by Molmil](/molmil-images/mine/5dfe) | 70S termination complex containing E. coli RF2 | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Hoffer, E.D, Dunham, C.M. | Deposit date: | 2015-08-26 | Release date: | 2016-10-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.09997559 Å) | Cite: | Uniformity of Peptide Release Is Maintained by Methylation of Release Factors. Cell Rep, 17, 2016
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2B3T
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![BU of 2b3t by Molmil](/molmil-images/mine/2b3t) | Structure of complex between E. coli translation termination factor RF1 and the PrmC methyltransferase | Descriptor: | Peptide chain release factor 1, Protein methyltransferase hemK, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Graille, M, Heurgue-Hamard, V, Champ, S, Mora, L, Scrima, N, Ulryck, N, van Tilbeurgh, H, Buckingham, R.H. | Deposit date: | 2005-09-21 | Release date: | 2006-01-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Molecular basis for bacterial class I release factor methylation by PrmC Mol.Cell, 20, 2005
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1ML5
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![BU of 1ml5 by Molmil](/molmil-images/mine/1ml5) | Structure of the E. coli ribosomal termination complex with release factor 2 | Descriptor: | 30S 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | Authors: | Klaholz, B.P, Pape, T, Zavialov, A.V, Myasnikov, A.G, Orlova, E.V, Vestergaard, B, Ehrenberg, M, van Heel, M. | Deposit date: | 2002-08-30 | Release date: | 2003-01-14 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (14 Å) | Cite: | Structure of the Escherichia coli ribosomal termination complex with release factor 2 Nature, 421, 2003
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1MI6
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![BU of 1mi6 by Molmil](/molmil-images/mine/1mi6) | Docking of the modified RF2 X-ray structure into the Low Resolution Cryo-EM map of RF2 E.coli 70S Ribosome | Descriptor: | peptide chain release factor RF-2 | Authors: | Rawat, U.B.S, Zavialov, A.V, Sengupta, J, Valle, M, Grassucci, R.A, Linde, J, Vestergaard, B, Ehrenberg, M, Frank, J. | Deposit date: | 2002-08-22 | Release date: | 2003-01-14 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (12.8 Å) | Cite: | A cryo-electron microscopic study of ribosome-bound termination factor RF2 Nature, 421, 2003
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2FVO
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![BU of 2fvo by Molmil](/molmil-images/mine/2fvo) | Docking of the modified RF1 X-ray structure into the Low Resolution Cryo-EM map of E.coli 70S Ribosome bound with RF1 | Descriptor: | Peptide chain release factor 1 | Authors: | Rawat, U, Gao, H, Zavialov, A, Gursky, R, Ehrenberg, M, Frank, J. | Deposit date: | 2006-01-31 | Release date: | 2006-04-04 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (12.8 Å) | Cite: | Interactions of the Release Factor RF1 with the Ribosome as Revealed by Cryo-EM. J.Mol.Biol., 357, 2006
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5J3C
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![BU of 5j3c by Molmil](/molmil-images/mine/5j3c) | |
5J30
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![BU of 5j30 by Molmil](/molmil-images/mine/5j30) | |
5J4D
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![BU of 5j4d by Molmil](/molmil-images/mine/5j4d) | |