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PDB: 98 results

6QWU
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4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus at pH 5.5 with Mn2+ and CoA.
Descriptor: COENZYME A, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, ...
Authors:Nguyen, M.C, Mourey, L, Pedelacq, J.D.
Deposit date:2019-03-06
Release date:2020-03-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Conformational flexibility of coenzyme A and its impact on the post-translational modification of acyl carrier proteins by 4'-phosphopantetheinyl transferases.
Febs J., 287, 2020
6QXQ
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4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus at pH 7 with Mn2+ and CoA.
Descriptor: COENZYME A, MANGANESE (II) ION, Possible 4'-phosphopantetheinyl transferase
Authors:Nguyen, M.C, Mourey, L, Pedelacq, J.D.
Deposit date:2019-03-07
Release date:2020-03-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Conformational flexibility of coenzyme A and its impact on the post-translational modification of acyl carrier proteins by 4'-phosphopantetheinyl transferases.
Febs J., 287, 2020
6QYG
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4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus at pH 8.5 with Mg2+ and CoA.
Descriptor: COENZYME A, MAGNESIUM ION, Possible 4'-phosphopantetheinyl transferase
Authors:Nguyen, M.C, Mourey, L, Pedelacq, J.D.
Deposit date:2019-03-08
Release date:2020-03-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Conformational flexibility of coenzyme A and its impact on the post-translational modification of acyl carrier proteins by 4'-phosphopantetheinyl transferases.
Febs J., 287, 2020
6QYF
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4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus at pH 4.6 with Mg2+ and CoA.
Descriptor: COENZYME A, MAGNESIUM ION, Possible 4'-phosphopantetheinyl transferase
Authors:Nguyen, M.C, Mourey, L, Pedelacq, J.D.
Deposit date:2019-03-08
Release date:2020-03-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Conformational flexibility of coenzyme A and its impact on the post-translational modification of acyl carrier proteins by 4'-phosphopantetheinyl transferases.
Febs J., 287, 2020
6QXR
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BU of 6qxr by Molmil
4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus at pH 8.5 with Mn2+ and CoA.
Descriptor: CALCIUM ION, COENZYME A, MANGANESE (II) ION, ...
Authors:Nguyen, M.C, Mourey, L, Pedelacq, J.D.
Deposit date:2019-03-07
Release date:2020-03-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Conformational flexibility of coenzyme A and its impact on the post-translational modification of acyl carrier proteins by 4'-phosphopantetheinyl transferases.
Febs J., 287, 2020
8QZH
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Crystal structure of apo-PptT from Mycobacterium tuberculosis
Descriptor: 4'-phosphopantetheinyl transferase PptT, ACETATE ION, MAGNESIUM ION
Authors:Gavalda, S, Carivenc, C, Mourey, L, Pedelacq, J.D.
Deposit date:2023-10-27
Release date:2024-06-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Catalytic Cycle of Type II 4'-Phosphopantetheinyl Transferases
Acs Catalysis, 14, 2024
8QZJ
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BU of 8qzj by Molmil
Crystal structure of PptT-ADP from Mycobacterium tuberculosis
Descriptor: 4'-phosphopantetheinyl transferase PptT, ADENOSINE-3'-5'-DIPHOSPHATE, MANGANESE (II) ION
Authors:Gavalda, S, Mourey, L, Pedelacq, J.D.
Deposit date:2023-10-27
Release date:2024-06-19
Method:X-RAY DIFFRACTION (2 Å)
Cite:Catalytic Cycle of Type II 4'-Phosphopantetheinyl Transferases
Acs Catalysis, 14, 2024
6U5T
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BU of 6u5t by Molmil
Electron cryomicroscopy Structure of S. cerevisiae FAS in the Apo state
Descriptor: 4'-PHOSPHOPANTETHEINE, FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, ...
Authors:Lou, J.W, Mazhab-Jafari, M.T.
Deposit date:2019-08-28
Release date:2019-10-16
Last modified:2019-10-30
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Electron cryomicroscopy observation of acyl carrier protein translocation in type I fungal fatty acid synthase.
Sci Rep, 9, 2019
7R49
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Crystal structure of the L. plantarum acyl carrier protein synthase (AcpS)in complex with D-alanyl carrier protein (DltC1)
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4'-PHOSPHOPANTETHEINE, D-alanyl carrier protein 1, ...
Authors:Nikolopoulos, N, Ravaud, S, Simorre, J.P, Grangeasse, C.
Deposit date:2022-02-08
Release date:2022-08-03
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:DltC acts as an interaction hub for AcpS, DltA and DltB in the teichoic acid D-alanylation pathway of Lactiplantibacillus plantarum.
Sci Rep, 12, 2022
7Q5S
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BU of 7q5s by Molmil
Protein community member fatty acid synthase complex from C. thermophilum
Descriptor: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase, 3-oxoacyl-[acyl-carrier-protein] reductase
Authors:Chojnowski, G, Skalidis, I, Kyrilis, F.L, Tueting, C, Hamdi, F, Kastritis, P.L.
Deposit date:2021-11-04
Release date:2022-02-02
Last modified:2023-12-13
Method:ELECTRON MICROSCOPY (4.47 Å)
Cite:Cryo-EM and artificial intelligence visualize endogenous protein community members.
Structure, 30, 2022
4DXE
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BU of 4dxe by Molmil
2.52 Angstrom resolution crystal structure of the acyl-carrier-protein synthase (AcpS)-acyl carrier protein (ACP) protein-protein complex from Staphylococcus aureus subsp. aureus COL
Descriptor: Acyl carrier protein, MALONATE ION, acyl-carrier-protein synthase
Authors:Halavaty, A.S, Minasov, G, Filippova, E.V, Dubrovska, I, Winsor, J, Shuvalova, L, Peterson, S.N, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2012-02-27
Release date:2012-03-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:2.52 Angstrom resolution crystal structure of the acyl-carrier-protein synthase (AcpS)-acyl carrier protein (ACP) protein-protein complex from Staphylococcus aureus subsp. aureus COL
To be Published
4MRT
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BU of 4mrt by Molmil
Structure of the Phosphopantetheine Transferase Sfp in Complex with Coenzyme A and a Peptidyl Carrier Protein
Descriptor: 4'-phosphopantetheinyl transferase sfp, COENZYME A, GLYCEROL, ...
Authors:Tufar, P, Rahighi, S, Kraas, F.I, Kirchner, D.K, Loehr, F, Henrich, E, Koepke, J, Dikic, I, Guentert, P, Marahiel, M.A, Doetsch, V.
Deposit date:2013-09-17
Release date:2014-04-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of a PCP/Sfp Complex Reveals the Structural Basis for Carrier Protein Posttranslational Modification.
Chem.Biol., 21, 2014
7TUI
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BU of 7tui by Molmil
Structure of C. albicans FAS in an inhibited state
Descriptor: FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta
Authors:Lou, J.W, Mazhab-Jafari, M.T.
Deposit date:2022-02-02
Release date:2023-02-15
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:Structure of C. albicans FAS in an inhibited state.
Not published
5VCB
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BU of 5vcb by Molmil
Crystal structure of holo-(acyl-carrier-protein) synthase:holo(acyl-carrier-protein) complex from Escherichia Coli.
Descriptor: 4'-PHOSPHOPANTETHEINE, Acyl carrier protein, Holo-[acyl-carrier-protein] synthase
Authors:Marcella, A.M, Barb, A.W.
Deposit date:2017-03-31
Release date:2017-11-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Structure, High Affinity, and Negative Cooperativity of the Escherichia coli Holo-(Acyl Carrier Protein):Holo-(Acyl Carrier Protein) Synthase Complex.
J. Mol. Biol., 429, 2017
6QL5
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BU of 6ql5 by Molmil
Structure of fatty acid synthase complex with bound gamma subunit from Saccharomyces cerevisiae at 2.8 angstrom
Descriptor: 4'-PHOSPHOPANTETHEINE, FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, ...
Authors:Singh, K, Graf, B, Linden, A, Sautner, V, Urlaub, H, Tittmann, K, Stark, H, Chari, A.
Deposit date:2019-01-31
Release date:2020-03-18
Last modified:2020-04-08
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase.
Cell, 180, 2020
6QL7
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BU of 6ql7 by Molmil
Structure of fatty acid synthase complex with bound gamma subunit from Saccharomyces cerevisiae at 4.6 angstrom
Descriptor: Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, Translation machinery-associated protein 17
Authors:Singh, K, Graf, B, Linden, A, Sautner, V, Urlaub, H, Tittmann, K, Stark, H, Chari, A.
Deposit date:2019-01-31
Release date:2020-03-18
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (4.6 Å)
Cite:Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase.
Cell, 180, 2020
3HMJ
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BU of 3hmj by Molmil
Saccharomyces cerevisiae FAS type I
Descriptor: (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, FLAVIN MONONUCLEOTIDE, ...
Authors:Johansson, P, Mulinacci, B, Koestler, C, Vollrath, R, Oesterhelt, D, Grininger, M.
Deposit date:2009-05-29
Release date:2009-09-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (4 Å)
Cite:Multimeric options for the auto-activation of the Saccharomyces cerevisiae FAS type I megasynthase
Structure, 17, 2009
4QVH
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BU of 4qvh by Molmil
Crystal structure of the essential Mycobacterium tuberculosis phosphopantetheinyl transferase PptT, solved as a fusion protein with maltose binding protein
Descriptor: CITRATE ANION, COENZYME A, GLYCEROL, ...
Authors:Jung, J, Bashiri, G, Johnston, J.M, Baker, E.N.
Deposit date:2014-07-15
Release date:2014-12-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of the essential Mycobacterium tuberculosis phosphopantetheinyl transferase PptT, solved as a fusion protein with maltose binding protein.
J.Struct.Biol., 188, 2014
6U5U
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BU of 6u5u by Molmil
Electron cryomicroscopy Structure of S. cerevisiae FAS in the KS-stalled state
Descriptor: 4'-PHOSPHOPANTETHEINE, FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, ...
Authors:Lou, J.W, Mazhab-Jafari, M.T.
Deposit date:2019-08-28
Release date:2019-10-16
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Electron cryomicroscopy observation of acyl carrier protein translocation in type I fungal fatty acid synthase.
Sci Rep, 9, 2019
6U5V
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BU of 6u5v by Molmil
Electron cryomicroscopy Structure of C. albicans FAS in the Apo state
Descriptor: 4'-PHOSPHOPANTETHEINE, FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, ...
Authors:Lou, J.W, Mazhab-Jafari, M.T.
Deposit date:2019-08-28
Release date:2019-10-16
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Electron cryomicroscopy observation of acyl carrier protein translocation in type I fungal fatty acid synthase.
Sci Rep, 9, 2019
6U5W
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BU of 6u5w by Molmil
Electron cryomicroscopy structure of C. albicans FAS in the KS-stalled state
Descriptor: FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, ...
Authors:Lou, J.W, Mazhab-Jafari, M.T.
Deposit date:2019-08-28
Release date:2019-10-16
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Electron cryomicroscopy observation of acyl carrier protein translocation in type I fungal fatty acid synthase.
Sci Rep, 9, 2019
2CG5
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BU of 2cg5 by Molmil
Structure of aminoadipate-semialdehyde dehydrogenase- phosphopantetheinyl transferase in complex with cytosolic acyl carrier protein and coenzyme A
Descriptor: COENZYME A, FATTY ACID SYNTHASE, L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE, ...
Authors:Bunkoczi, G, Joshi, A, Papagrigoriu, E, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, von Delft, F, Smith, S, Oppermann, U.
Deposit date:2006-02-27
Release date:2006-03-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mechanism and Substrate Recognition of Human Holo Acp Synthase.
Chem.Biol., 14, 2007
6WC7
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BU of 6wc7 by Molmil
Acyl carrier protein (ACP) domain bound to dehydratase (DH) domain in fungal fatty acid synthase (FAS)
Descriptor: Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta
Authors:Lou, J.W, Mazhab-Jafari, M.T.
Deposit date:2020-03-29
Release date:2020-06-03
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Steric occlusion regulates proximal interactions of acyl carrier protein domain in fungal fatty acid synthase.
Commun Biol, 3, 2020
7BC4
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BU of 7bc4 by Molmil
Cryo-EM structure of fatty acid synthase (FAS) from Pichia pastoris
Descriptor: FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta
Authors:Snowden, J.S, Alzahrani, J, Sherry, L, Stacey, M, Rowlands, D.J, Ranson, N.A, Stonehouse, N.J.
Deposit date:2020-12-18
Release date:2021-05-19
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insight into Pichia pastoris fatty acid synthase.
Sci Rep, 11, 2021
7BC5
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Cryo-EM structure of ACP domain from Pichia pastoris fatty acid synthase (FAS)
Descriptor: Fatty acid synthase subunit alpha
Authors:Snowden, J.S, Alzahrani, J, Sherry, L, Stacey, M, Rowlands, D.J, Ranson, N.A, Stonehouse, N.J.
Deposit date:2020-12-18
Release date:2021-05-19
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insight into Pichia pastoris fatty acid synthase.
Sci Rep, 11, 2021

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