7QI4
| Human mitochondrial ribosome at 2.2 A resolution (bound to partly built tRNAs and mRNA) | Descriptor: | 1,4-DIAMINOBUTANE, 12S mitochondrial rRNA, 16S mitochondrial rRNA, ... | Authors: | Singh, V, Itoh, Y, Amunts, A. | Deposit date: | 2021-12-14 | Release date: | 2022-07-13 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.21 Å) | Cite: | Structure of mitoribosome reveals mechanism of mRNA binding, tRNA interactions with L1 stalk, roles of cofactors and rRNA modifications. Biorxiv, 2023
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7O9M
| Human mitochondrial ribosome large subunit assembly intermediate with MTERF4-NSUN4, MRM2, MTG1 and the MALSU module | Descriptor: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | Authors: | Valentin Gese, G, Hallberg, B.M. | Deposit date: | 2021-04-16 | Release date: | 2021-06-30 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Structural basis for late maturation steps of the human mitoribosomal large subunit. Nat Commun, 12, 2021
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7PO4
| Assembly intermediate of human mitochondrial ribosome large subunit (largely unfolded rRNA with MALSU1, L0R8F8 and ACP) | Descriptor: | 16SrRNA, 39S ribosomal protein L10, mitochondrial, ... | Authors: | Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A. | Deposit date: | 2021-09-08 | Release date: | 2022-06-15 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.56 Å) | Cite: | Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature, 606, 2022
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6ZM6
| Human mitochondrial ribosome in complex with mRNA, A/A tRNA and P/P tRNA | Descriptor: | 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ... | Authors: | Itoh, Y, Andrell, J, Amunts, A. | Deposit date: | 2020-07-01 | Release date: | 2021-01-13 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.59 Å) | Cite: | Mechanism of membrane-tethered mitochondrial protein synthesis. Science, 371, 2021
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7QI5
| Human mitochondrial ribosome in complex with mRNA, A/A-, P/P- and E/E-tRNAs at 2.63 A resolution | Descriptor: | 1,4-DIAMINOBUTANE, 12S mitochondrial rRNA, 16S mitochondrial rRNA, ... | Authors: | Singh, V, Itoh, Y, Amunts, A. | Deposit date: | 2021-12-14 | Release date: | 2023-07-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.63 Å) | Cite: | Structure of mitoribosome reveals mechanism of mRNA binding, tRNA interactions with L1 stalk, roles of cofactors and rRNA modifications. Biorxiv, 2023
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8ANY
| Human mitochondrial ribosome in complex with LRPPRC, SLIRP, A-site, P-site, E-site tRNAs and mRNA | Descriptor: | 1,4-DIAMINOBUTANE, 12S mitochondrial rRNA, 16S mitochondrial rRNA, ... | Authors: | Singh, V, Itoh, Y, Amunts, A. | Deposit date: | 2022-08-06 | Release date: | 2023-08-16 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Structural basis of LRPPRC-SLIRP-dependent translation by the
mitoribosome To Be Published
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6ZM5
| Human mitochondrial ribosome in complex with OXA1L, mRNA, A/A tRNA, P/P tRNA and nascent polypeptide | Descriptor: | 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ... | Authors: | Itoh, Y, Andrell, J, Amunts, A. | Deposit date: | 2020-07-01 | Release date: | 2021-01-13 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Mechanism of membrane-tethered mitochondrial protein synthesis. Science, 371, 2021
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8OIT
| 39S human mitochondrial large ribosomal subunit with mtRF1 and P-site tRNA | Descriptor: | 16S rRNA, 39S ribosomal protein L1, mitochondrial, ... | Authors: | Saurer, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Ban, N. | Deposit date: | 2023-03-23 | Release date: | 2023-06-14 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Molecular basis of translation termination at noncanonical stop codons in human mitochondria. Science, 380, 2023
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6VMI
| Structure of the human mitochondrial ribosome-EF-G1 complex (ClassIII) | Descriptor: | 12s rRNA, 16s rRNA, 28S ribosomal protein S10, ... | Authors: | Sharma, M.R, Koripella, R.K, Agrawal, R.K. | Deposit date: | 2020-01-28 | Release date: | 2020-08-05 | Last modified: | 2021-02-17 | Method: | ELECTRON MICROSCOPY (2.96 Å) | Cite: | Structures of the human mitochondrial ribosome bound to EF-G1 reveal distinct features of mitochondrial translation elongation. Nat Commun, 11, 2020
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6VLZ
| Structure of the human mitochondrial ribosome-EF-G1 complex (ClassI) | Descriptor: | 12s rRNA, 16s rRNA, 28S ribosomal protein S10, ... | Authors: | Sharma, M.R, Koripella, R.K, Agrawal, R.K. | Deposit date: | 2020-01-27 | Release date: | 2020-08-05 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.97 Å) | Cite: | Structures of the human mitochondrial ribosome bound to EF-G1 reveal distinct features of mitochondrial translation elongation. Nat Commun, 11, 2020
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7QI6
| Human mitochondrial ribosome in complex with mRNA, A/P- and P/E-tRNAs at 2.98 A resolution | Descriptor: | 1,4-DIAMINOBUTANE, 12S mitochondrial rRNA, 16S mitochondrial rRNA, ... | Authors: | Singh, V, Itoh, Y, Amunts, A. | Deposit date: | 2021-12-14 | Release date: | 2023-05-17 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | Structure of mitoribosome reveals mechanism of mRNA binding, tRNA interactions with L1 stalk, roles of cofactors and rRNA modifications. Biorxiv, 2023
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7PO2
| Initiation complex of human mitochondrial ribosome small subunit with IF2, fMet-tRNAMet and mRNA | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A. | Deposit date: | 2021-09-08 | Release date: | 2022-06-15 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.09 Å) | Cite: | Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature, 606, 2022
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7O9K
| Human mitochondrial ribosome large subunit assembly intermediate with MTERF4-NSUN4, MRM2, MTG1, the MALSU module, GTPBP5 and mtEF-Tu | Descriptor: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | Authors: | Valentin Gese, G, Hallberg, B.M. | Deposit date: | 2021-04-16 | Release date: | 2021-06-30 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis for late maturation steps of the human mitoribosomal large subunit. Nat Commun, 12, 2021
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8OIR
| 55S human mitochondrial ribosome with mtRF1 and P-site tRNA | Descriptor: | 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ... | Authors: | Saurer, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Ban, N. | Deposit date: | 2023-03-23 | Release date: | 2023-06-14 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Molecular basis of translation termination at noncanonical stop codons in human mitochondria. Science, 380, 2023
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7L20
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7L08
| Cryo-EM structure of the human 55S mitoribosome-RRFmt complex. | Descriptor: | 12S rRNA, 16S RRNA, 28S ribosomal protein S10, ... | Authors: | Koripella, R, Agrawal, E.K, Deep, A, Agrawal, R.K. | Deposit date: | 2020-12-11 | Release date: | 2021-05-12 | Last modified: | 2021-12-01 | Method: | ELECTRON MICROSCOPY (3.49 Å) | Cite: | Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance. Nat Commun, 12, 2021
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6ZSC
| Human mitochondrial ribosome in complex with E-site tRNA | Descriptor: | 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ... | Authors: | Aibara, S, Singh, V, Modelska, A, Amunts, A. | Deposit date: | 2020-07-15 | Release date: | 2020-09-16 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of mitochondrial translation. Elife, 9, 2020
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6ZSD
| Human mitochondrial ribosome in complex with mRNA, P-site tRNA and E-site tRNA | Descriptor: | 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ... | Authors: | Aibara, S, Singh, V, Modelska, A, Amunts, A. | Deposit date: | 2020-07-15 | Release date: | 2020-09-16 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural basis of mitochondrial translation. Elife, 9, 2020
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7OG4
| Human mitochondrial ribosome in complex with P/E-tRNA | Descriptor: | 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ... | Authors: | Aibara, S, Singh, V, Modelska, A, Amunts, A. | Deposit date: | 2021-05-06 | Release date: | 2021-06-23 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis of mitochondrial translation. Elife, 9, 2020
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6ZS9
| Human mitochondrial ribosome in complex with ribosome recycling factor | Descriptor: | 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ... | Authors: | Aibara, S, Singh, V, Modelska, A, Amunts, A. | Deposit date: | 2020-07-15 | Release date: | 2020-10-14 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural basis of mitochondrial translation. Elife, 9, 2020
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6ZSG
| Human mitochondrial ribosome in complex with mRNA, A-site tRNA, P-site tRNA and E-site tRNA | Descriptor: | 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ... | Authors: | Aibara, S, Singh, V, Modelska, A, Amunts, A. | Deposit date: | 2020-07-15 | Release date: | 2020-10-14 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural basis of mitochondrial translation. Elife, 9, 2020
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6ZSA
| Human mitochondrial ribosome bound to mRNA, A-site tRNA and P-site tRNA | Descriptor: | 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ... | Authors: | Aibara, S, Singh, V, Modelska, A, Amunts, A. | Deposit date: | 2020-07-15 | Release date: | 2020-10-21 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural basis of mitochondrial translation. Elife, 9, 2020
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6ZSB
| Human mitochondrial ribosome in complex with mRNA and P-site tRNA | Descriptor: | 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ... | Authors: | Aibara, S, Singh, V, Modelska, A, Amunts, A. | Deposit date: | 2020-07-15 | Release date: | 2020-09-16 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structural basis of mitochondrial translation. Elife, 9, 2020
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6ZSE
| Human mitochondrial ribosome in complex with mRNA, A/P-tRNA and P/E-tRNA | Descriptor: | 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ... | Authors: | Aibara, S, Singh, V, Modelska, A, Amunts, A. | Deposit date: | 2020-07-15 | Release date: | 2020-09-16 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (5 Å) | Cite: | Structural basis of mitochondrial translation. Elife, 9, 2020
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