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PDB: 39 results

8C2F
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BU of 8c2f by Molmil
Structure of 14-3-3 sigma delta C with electrophilic peptide 3MHR-5
Descriptor: 14-3-3 protein sigma, ARG-ALA-HIS-SEP-CYS-PRO-ALA-SER-LEU-GLN, CHLORIDE ION, ...
Authors:van den Oetelaar, M.C.M, Ottmann, C.
Deposit date:2022-12-22
Release date:2023-11-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A simple method for developing lysine targeted covalent protein reagents.
Nat Commun, 14, 2023
6HIL
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BU of 6hil by Molmil
X-ray structure of TEAD1(Y421H mutant) complexed with YAP(wildtype): Molecular and structural characterization of a TEAD mutation at the origin of Sveinsson's chorioretinal atrophy
Descriptor: MYRISTIC ACID, Transcriptional coactivator YAP1, Transcriptional enhancer factor TEF-1
Authors:Kallen, J.
Deposit date:2018-08-30
Release date:2019-04-03
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular and structural characterization of a TEAD mutation at the origin of Sveinsson's chorioretinal atrophy.
Febs J., 286, 2019
3KYS
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BU of 3kys by Molmil
Crystal structure of human YAP and TEAD complex
Descriptor: 65 kDa Yes-associated protein, Transcriptional enhancer factor TEF-1
Authors:Li, Z, Zhao, B, Wang, P, Chen, F, Dong, Z, Yang, H, Guan, K.L, Xu, Y.
Deposit date:2009-12-07
Release date:2010-02-23
Last modified:2020-10-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural insights into the YAP and TEAD complex
Genes Dev., 24, 2010
1K5R
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BU of 1k5r by Molmil
YAP65 WW domain S24-Amino-Ethylsulfanyl-Acetic Acid mutant
Descriptor: 65 KDA YES-ASSOCIATED PROTEIN, Fragment of WBP-1
Authors:Ferguson, N, Pires, J.R, Toepert, F, Johnson, C.M, Pan, Y.P, Volkmer-Engert, R, Schneider-Mergener, J, Daggett, V, Oschkinat, H, Fersht, A.R.
Deposit date:2001-10-12
Release date:2001-11-02
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Using flexible loop mimetics to extend phi-value analysis to secondary structure interactions.
Proc.Natl.Acad.Sci.USA, 98, 2001
2LAX
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BU of 2lax by Molmil
Structure of first WW domain of human YAP in complex with a human Smad1 doubly-phosphorilated derived peptide.
Descriptor: Mothers against decapentaplegic homolog 1, Yorkie homolog
Authors:Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J.
Deposit date:2011-03-22
Release date:2011-07-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
1K9Q
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BU of 1k9q by Molmil
YAP65 WW domain complexed to N-(n-octyl)-GPPPY-NH2
Descriptor: 65 kDa Yes-associated protein, N-OCTANE, WW domain binding protein-1
Authors:Pires, J.R, Taha-Nejad, F, Toepert, F, Ast, T, Hoffmuller, U, Schneider-Mergener, J, Kuhne, R, Macias, M.J, Oschkinat, H.
Deposit date:2001-10-30
Release date:2001-12-28
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Solution structures of the YAP65 WW domain and the variant L30 K in complex with the peptides GTPPPPYTVG, N-(n-octyl)-GPPPY and PLPPY and the application of peptide libraries reveal a minimal binding epitope.
J.Mol.Biol., 314, 2001
1K9R
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BU of 1k9r by Molmil
YAP65 WW domain complexed to Acetyl-PLPPY
Descriptor: 65 kDa Yes-associated protein, WW domain binding protein-1
Authors:Pires, J.R, Taha-Nejad, F, Toepert, F, Ast, T, Hoffmuller, U, Schneider-Mergener, J, Kuhne, R, Macias, M.J, Oschkinat, H.
Deposit date:2001-10-30
Release date:2001-12-28
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Solution structures of the YAP65 WW domain and the variant L30 K in complex with the peptides GTPPPPYTVG, N-(n-octyl)-GPPPY and PLPPY and the application of peptide libraries reveal a minimal binding epitope.
J.Mol.Biol., 314, 2001
2LTV
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BU of 2ltv by Molmil
YAP WW2 in complex with a Smad7 derived peptide
Descriptor: Smad7 derived peptide, Yorkie homolog
Authors:Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J.
Deposit date:2012-06-04
Release date:2012-11-21
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways.
Structure, 20, 2012
2LAY
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BU of 2lay by Molmil
Structure of the first WW domain of human YAP in complex with a phosphorylated human Smad1 derived peptide
Descriptor: Mothers against decapentaplegic homolog 1, Yorkie homolog
Authors:Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J.
Deposit date:2011-03-22
Release date:2011-07-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
5YDX
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BU of 5ydx by Molmil
NMR structure of YAP1-2 WW1 domain with LATS1 PPxY motif complex
Descriptor: WW domain with PPxY motif
Authors:Fan, J.S, Sivaraman, J.
Deposit date:2017-09-15
Release date:2018-05-02
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Biophysical studies and NMR structure of YAP2 WW domain - LATS1 PPxY motif complexes reveal the basis of their interaction.
Oncotarget, 9, 2018
5YDY
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BU of 5ydy by Molmil
NMR structure of YAP1-2 WW2 domain with LATS1 PPxY motif complex
Descriptor: WW2 domain and PPxY motif complex
Authors:Fan, J.S, Sivaraman, J.
Deposit date:2017-09-15
Release date:2018-05-02
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Biophysical studies and NMR structure of YAP2 WW domain - LATS1 PPxY motif complexes reveal the basis of their interaction.
Oncotarget, 9, 2018
2LTW
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BU of 2ltw by Molmil
YAP WW1 in complex with a Smad7 derived peptide
Descriptor: Smad7 derived peptide, Yorkie homolog
Authors:Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J.
Deposit date:2012-06-04
Release date:2012-11-21
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways.
Structure, 20, 2012
2LAW
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BU of 2law by Molmil
Structure of the second WW domain from human YAP in complex with a human Smad1 derived peptide
Descriptor: Mothers against decapentaplegic homolog 1, Yorkie homolog
Authors:Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J.
Deposit date:2011-03-22
Release date:2011-07-06
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
1JMQ
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BU of 1jmq by Molmil
YAP65 (L30K mutant) WW domain in Complex with GTPPPPYTVG peptide
Descriptor: 65 KDA YES-ASSOCIATED PROTEIN, WW Domain Binding Protein-1
Authors:Pires, J.R, Taha-Nejad, F, Toepert, F, Ast, T, Hoffmuller, U, Schneider-Mergener, J, Kuhne, R, Macias, M.J, Oschkinat, H.
Deposit date:2001-07-19
Release date:2001-12-21
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structures of the YAP65 WW domain and the variant L30 K in complex with the peptides GTPPPPYTVG, N-(n-octyl)-GPPPY and PLPPY and the application of peptide libraries reveal a minimal binding epitope.
J.Mol.Biol., 314, 2001
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