9FH9
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9FGQ
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7CJ0
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3AFA
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![BU of 3afa by Molmil](/molmil-images/mine/3afa) | The human nucleosome structure | Descriptor: | 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... | Authors: | Tachiwana, H, Kagawa, W, Osakabe, A, Koichiro, K, Shiga, T, Kimura, H, Kurumizaka, H. | Deposit date: | 2010-02-24 | Release date: | 2010-05-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis of instability of the nucleosome containing a testis-specific histone variant, human H3T Proc.Natl.Acad.Sci.USA, 107, 2010
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3NQU
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6L9Z
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![BU of 6l9z by Molmil](/molmil-images/mine/6l9z) | 338 bp di-nucleosome assembled with linker histone H1.X | Descriptor: | CALCIUM ION, CHLORIDE ION, DNA (338-MER), ... | Authors: | Adhireksan, Z, Sharma, D, Lee, P.L, Davey, C.A. | Deposit date: | 2019-11-11 | Release date: | 2021-02-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Engineering nucleosomes for generating diverse chromatin assemblies. Nucleic Acids Res., 49, 2021
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5JRG
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![BU of 5jrg by Molmil](/molmil-images/mine/5jrg) | Crystal structure of the nucleosome containing the DNA with tetrahydrofuran (THF) | Descriptor: | CHLORIDE ION, DNA (145-MER), Histone H2A type 1-B/E, ... | Authors: | Osakabe, A, Arimura, Y, Horikoshi, N, Kurumizaka, H. | Deposit date: | 2016-05-06 | Release date: | 2017-03-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Polymorphism of apyrimidinic DNA structures in the nucleosome Sci Rep, 7, 2017
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6JR0
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![BU of 6jr0 by Molmil](/molmil-images/mine/6jr0) | Crystal structure of the human nucleosome phased with 12 selenium atoms | Descriptor: | CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... | Authors: | Saotome, M, Horikoshi, N, Urano, K, Kujirai, T, Yuzurihara, H, Kurumizaka, H, Kagawa, W. | Deposit date: | 2019-04-02 | Release date: | 2019-10-02 | Last modified: | 2019-10-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure determination of the nucleosome core particle by selenium SAD phasing. Acta Crystallogr D Struct Biol, 75, 2019
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3AV1
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![BU of 3av1 by Molmil](/molmil-images/mine/3av1) | The human nucleosome structure containing the histone variant H3.2 | Descriptor: | 146-MER DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Tachiwana, H, Osakabe, A, Shiga, T, Miya, Y, Kimura, H, Kagawa, W, Kurumizaka, H. | Deposit date: | 2011-02-18 | Release date: | 2011-06-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of human nucleosomes containing major histone H3 variants Acta Crystallogr.,Sect.D, 67, 2011
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2CV5
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![BU of 2cv5 by Molmil](/molmil-images/mine/2cv5) | Crystal structure of human nucleosome core particle | Descriptor: | CHLORIDE ION, DNA (146-MER), Histone H2A.a, ... | Authors: | Tsunaka, Y, Kajimura, N, Tate, S, Morikawa, K. | Deposit date: | 2005-05-31 | Release date: | 2005-06-28 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Alteration of the nucleosomal DNA path in the crystal structure of a human nucleosome core particle Nucleic Acids Res., 33, 2005
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8Q3M
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![BU of 8q3m by Molmil](/molmil-images/mine/8q3m) | Structure of Nucleosome Core with a Bound Kaposi Sarcoma Associated Herpesvirus LANA Peptide Having a Methionine to Ornithine Substitution | Descriptor: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | Authors: | De Falco, L, Batchelor, L.K, Dyson, P.J, Davey, C.A. | Deposit date: | 2023-08-04 | Release date: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.503 Å) | Cite: | Viral peptide conjugates for metal-warhead delivery to chromatin. Rsc Adv, 14, 2024
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8GUK
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![BU of 8guk by Molmil](/molmil-images/mine/8guk) | Human nucleosome core particle (free form) | Descriptor: | DNA (147-mer), Histone H2A type 1, Histone H2B type 1-J, ... | Authors: | Onishi, S, Sato, K, Nishizawa, T, Nureki, O, Ogata, K, Sengoku, T. | Deposit date: | 2022-09-12 | Release date: | 2023-09-20 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (2.51 Å) | Cite: | Structure of the human Bre1 complex bound to the nucleosome. Nat Commun, 15, 2024
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8OX0
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![BU of 8ox0 by Molmil](/molmil-images/mine/8ox0) | Structure of apo telomeric nucleosome | Descriptor: | Histone H2A type 1-C, Histone H2B type 1-C/E/F/G/I, Histone H3.1, ... | Authors: | Hu, H, van Roon, A.M.M, Ghanim, G.E, Ahsan, B, Oluwole, A, Peak-Chew, S, Robinson, C.V, Nguyen, T.H.D. | Deposit date: | 2023-04-28 | Release date: | 2023-08-30 | Last modified: | 2023-09-06 | Method: | ELECTRON MICROSCOPY (2.52 Å) | Cite: | Structural basis of telomeric nucleosome recognition by shelterin factor TRF1. Sci Adv, 9, 2023
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5B0Y
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![BU of 5b0y by Molmil](/molmil-images/mine/5b0y) | Crystal structure of the nucleosome containing histone H3 with the crotonylated lysine 122 | Descriptor: | CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... | Authors: | Suzuki, Y, Horikoshi, N, Kurumizaka, H. | Deposit date: | 2015-11-13 | Release date: | 2016-01-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.557 Å) | Cite: | Crystal structure of the nucleosome containing histone H3 with crotonylated lysine 122 Biochem.Biophys.Res.Commun., 469, 2016
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7XCR
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![BU of 7xcr by Molmil](/molmil-images/mine/7xcr) | Cryo-EM structure of Dot1L and H2BK34ub-H3K79Nle nucleosome 1:1 complex | Descriptor: | DNA (146-MER), Histone H2A, Histone H2B type 1-K, ... | Authors: | Ai, H.S, Liu, A.J, Lou, Z.Y, Liu, L. | Deposit date: | 2022-03-25 | Release date: | 2022-04-20 | Last modified: | 2022-09-07 | Method: | ELECTRON MICROSCOPY (2.57 Å) | Cite: | H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity. Nat.Chem.Biol., 18, 2022
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5ZBX
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![BU of 5zbx by Molmil](/molmil-images/mine/5zbx) | The crystal structure of the nucleosome containing histone H3.1 CATD(V76Q, K77D) | Descriptor: | CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... | Authors: | Arimura, Y, Takagi, H, Kurumizaka, H. | Deposit date: | 2018-02-13 | Release date: | 2019-02-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | The CENP-A centromere targeting domain facilitates H4K20 monomethylation in the nucleosome by structural polymorphism. Nat Commun, 10, 2019
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8SYP
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![BU of 8syp by Molmil](/molmil-images/mine/8syp) | Genomic CX3CR1 nucleosome | Descriptor: | DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | Authors: | Lian, T, Guan, R, Bai, Y. | Deposit date: | 2023-05-25 | Release date: | 2023-11-01 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBP alpha. Nat.Struct.Mol.Biol., 31, 2024
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6E0P
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5XF3
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![BU of 5xf3 by Molmil](/molmil-images/mine/5xf3) | Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having a 1,2-diphenylethylenediamine linker (R,R-configuration) | Descriptor: | (1R,2R)-1,2-diphenylethane-1,2-diamine, DNA (145-MER), Histone H2A type 1-B/E, ... | Authors: | Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A. | Deposit date: | 2017-04-07 | Release date: | 2017-10-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation Nat Commun, 8, 2017
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6LE9
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![BU of 6le9 by Molmil](/molmil-images/mine/6le9) | The Human Telomeric Nucleosome Displays Distinct Structural and Dynamic Properties | Descriptor: | Histone H2A type 1-B/E, Histone H2B type 1-K, Histone H3.1, ... | Authors: | Soman, A, Liew, C.W, Teo, H.L, Berezhnoy, N, Korolev, N, Rhodes, D, Nordenskiold, L. | Deposit date: | 2019-11-24 | Release date: | 2020-04-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The human telomeric nucleosome displays distinct structural and dynamic properties. Nucleic Acids Res., 48, 2020
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6L9H
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![BU of 6l9h by Molmil](/molmil-images/mine/6l9h) | The Human Telomeric Nucleosome Displays Distinct Structural and Dynamic Properties | Descriptor: | Histone H2A type 1-B/E, Histone H2B type 1-K, Histone H3.1, ... | Authors: | Soman, A, Liew, C.W, Teo, H.L, Berezhnoy, N, Korolev, N, Rhodes, D, Nordenskiold, L. | Deposit date: | 2019-11-10 | Release date: | 2020-04-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The human telomeric nucleosome displays distinct structural and dynamic properties. Nucleic Acids Res., 48, 2020
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7U0G
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![BU of 7u0g by Molmil](/molmil-images/mine/7u0g) | structure of LIN28b nucleosome bound 3 OCT4 | Descriptor: | DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | Authors: | Lian, T, Guan, R, Bai, Y. | Deposit date: | 2022-02-18 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural mechanism of LIN28B nucleosome targeting by OCT4. Mol.Cell, 83, 2023
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7U0I
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![BU of 7u0i by Molmil](/molmil-images/mine/7u0i) | Structure of LIN28b nucleosome bound 2 OCT4 | Descriptor: | DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | Authors: | Tengfei, L, Guan, R, Bai, Y. | Deposit date: | 2022-02-18 | Release date: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural mechanism of LIN28B nucleosome targeting by OCT4. Mol.Cell, 83, 2023
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6V2K
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![BU of 6v2k by Molmil](/molmil-images/mine/6v2k) | The nucleosome structure after H2A-H2B exchange | Descriptor: | CHLORIDE ION, DNA (146-MER), Histone H2A, ... | Authors: | Arimura, Y, Hirano, R, Kurumizaka, H. | Deposit date: | 2019-11-24 | Release date: | 2020-11-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Histone variant H2A.B-H2B dimers are spontaneously exchanged with canonical H2A-H2B in the nucleosome. Commun Biol, 4, 2021
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5B2J
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![BU of 5b2j by Molmil](/molmil-images/mine/5b2j) | Human nucleosome containing CpG methylated DNA | Descriptor: | DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Fujii, Y, Wakamori, M, Umehara, T, Yokoyama, S. | Deposit date: | 2016-01-18 | Release date: | 2016-06-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of human nucleosome core particle containing enzymatically introduced CpG methylation. Febs Open Bio, 6, 2016
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