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PDB: 5 results
7JK1
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BU of 7jk1 by Molmil
Human PrimPol inserting correct dCTP opposite the 8-oxoguanine lesion
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Rechkoblit, O, Aggarwal, A.K.
Deposit date:2020-07-27
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Structural basis of DNA synthesis opposite 8-oxoguanine by human PrimPol primase-polymerase.
Nat Commun, 12, 2021
7JKL
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BU of 7jkl by Molmil
Human PrimPol misinserting dATP opposite the 8-oxoguanine lesion (3'-end base of the primer strand is 2',3'-dideoxy-terminated).
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*GP*TP*GP*TP*GP*GP*TP*AP*GP*CP*(DDG))-3'), ...
Authors:Rechkoblit, O, Aggarwal, A.K.
Deposit date:2020-07-28
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.384 Å)
Cite:Structural basis of DNA synthesis opposite 8-oxoguanine by human PrimPol primase-polymerase.
Nat Commun, 12, 2021
7JLG
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BU of 7jlg by Molmil
Human PrimPol extending from the erroneous primer base A opposite the 8-oxoguanine lesion
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Rechkoblit, O, Aggarwal, A.K.
Deposit date:2020-07-29
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structural basis of DNA synthesis opposite 8-oxoguanine by human PrimPol primase-polymerase.
Nat Commun, 12, 2021
7JKP
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BU of 7jkp by Molmil
Human PrimPol misinserting dATP opposite the 8-oxoguanine lesion
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*GP*TP*GP*TP*GP*GP*TP*AP*GP*CP*G)-3'), ...
Authors:Rechkoblit, O, Aggarwal, A.K.
Deposit date:2020-07-28
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.592 Å)
Cite:Structural basis of DNA synthesis opposite 8-oxoguanine by human PrimPol primase-polymerase.
Nat Commun, 12, 2021
7JL8
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BU of 7jl8 by Molmil
Human PrimPol extending from the correct primer base C opposite the 8-oxoguanine lesion
Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, ...
Authors:Rechkoblit, O, Aggarwal, A.K.
Deposit date:2020-07-29
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of DNA synthesis opposite 8-oxoguanine by human PrimPol primase-polymerase.
Nat Commun, 12, 2021

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