PDB: 91 件ウェブページステータス検索Chemie searchBIRD

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1Z0W	Crystal Structure of A. fulgidus Lon proteolytic domain at 1.2A resolution 分子名称: CALCIUM ION, Putative protease La homolog type 著者 Botos, I, Melnikov, E.E, Cherry, S, Kozlov, S, Makhovskaya, O.V, Tropea, J.E, Gustchina, A, Rotanova, T.V, Wlodawer, A. 登録日 2005-03-02 公開日 2005-08-02 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Atomic-resolution Crystal Structure of the Proteolytic Domain of Archaeoglobus fulgidus Lon Reveals the Conformational Variability in the Active Sites of Lon Proteases J.Mol.Biol., 351, 2005
1Z0B	Crystal Structure of A. fulgidus Lon proteolytic domain E506A mutant 分子名称: CALCIUM ION, Putative protease La homolog type 著者 Botos, I, Melnikov, E.E, Cherry, S, Kozlov, S, Makhovskaya, O.V, Tropea, J.E, Gustchina, A, Rotanova, T.V, Wlodawer, A. 登録日 2005-03-01 公開日 2005-08-02 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Atomic-resolution Crystal Structure of the Proteolytic Domain of Archaeoglobus fulgidus Lon Reveals the Conformational Variability in the Active Sites of Lon Proteases J.Mol.Biol., 351, 2005
1Z0C	Crystal Structure of A. fulgidus Lon proteolytic domain D508A mutant 分子名称: Putative protease La homolog type 著者 Botos, I, Melnikov, E.E, Cherry, S, Kozlov, S, Makhovskaya, O.V, Tropea, J.E, Gustchina, A, Rotanova, T.V, Wlodawer, A. 登録日 2005-03-01 公開日 2005-08-02 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Atomic-resolution Crystal Structure of the Proteolytic Domain of Archaeoglobus fulgidus Lon Reveals the Conformational Variability in the Active Sites of Lon Proteases J.Mol.Biol., 351, 2005
1RRE	Crystal structure of E.coli Lon proteolytic domain 分子名称: ATP-dependent protease La, SULFATE ION 著者 Botos, I, Melnikov, E.E, Cherry, S, Tropea, J.E, Khalatova, A.G, Rasulova, F, Dauter, Z, Maurizi, M.R, Rotanova, T.V, Wlodawer, A, Gustchina, A. 登録日 2003-12-08 公開日 2004-02-03 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 The catalytic domain of Escherichia coli Lon protease has a unique fold and a Ser-Lys dyad in the active site J.Biol.Chem., 279, 2004
4YPM	Crystal structure of a LonA protease domain in complex with bortezomib 分子名称: CITRIC ACID, DI(HYDROXYETHYL)ETHER, Lon protease, ... 著者 Lin, C.-C, Chang, C.-I. 登録日 2015-03-13 公開日 2016-03-16 最終更新日 2016-05-18 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural Basis for the Magnesium-Dependent Activation and Hexamerization of the Lon AAA+ Protease Structure, 24, 2016
8DVH	Crystal structure of ATP-dependent Lon protease from Bacillus subtillis (BsLonBA) 分子名称: Lon protease 2, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, SODIUM ION 著者 Sekula, B, Li, M, Gustchina, A, Wlodawer, A. 登録日 2022-07-29 公開日 2022-11-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Unique Structural Fold of LonBA Protease from Bacillus subtilis, a Member of a Newly Identified Subfamily of Lon Proteases. Int J Mol Sci, 23, 2022
1XHK	Crystal structure of M. jannaschii Lon proteolytic domain 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Putative protease La homolog, SULFATE ION 著者 Im, Y.J, Na, Y, Kang, G.B, Rho, S.-H, Kim, M.-K, Lee, J.H, Chung, C.H, Eom, S.H. 登録日 2004-09-20 公開日 2004-10-05 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The active site of a lon protease from Methanococcus jannaschii distinctly differs from the canonical catalytic Dyad of Lon proteases. J.Biol.Chem., 279, 2004
4FWG	Crystal structure of the Lon-like protease MtaLonC in complex with lactacystin 分子名称: Omuralide, open form, PHOSPHATE ION, ... 著者 Chang, C.I, Kuo, C.I, Huang, K.F. 登録日 2012-07-01 公開日 2013-06-26 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Structures of an ATP-independent Lon-like protease and its complexes with covalent inhibitors Acta Crystallogr.,Sect.D, 69, 2013
4FW9	Crystal structure of the Lon-like protease MtaLonC 分子名称: PHOSPHATE ION, TTC1975 peptidase 著者 Chang, C.I, Ihara, K, Kuo, C.I, Huang, K.F, Wakatsuki, S. 登録日 2012-06-30 公開日 2013-06-26 最終更新日 2013-09-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structures of an ATP-independent Lon-like protease and its complexes with covalent inhibitors Acta Crystallogr.,Sect.D, 69, 2013
3K1J	Crystal structure of Lon protease from Thermococcus onnurineus NA1 分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Cha, S.S, An, Y.J. 登録日 2009-09-28 公開日 2010-09-22 最終更新日 2014-02-12 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of Lon protease: molecular architecture of gated entry to a sequestered degradation chamber Embo J., 29, 2010
2X36	Structure of the proteolytic domain of the Human Mitochondrial Lon protease 分子名称: LON PROTEASE HOMOLOG, MITOCHONDRIAL 著者 Garcia, J, Ondrovicova, G, Blagova, E, Levdikov, V.M, Bauer, J.A, Kutejova, E, Wilkinson, A.J, Wilson, K.S. 登録日 2010-01-21 公開日 2010-05-19 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of the Catalytic Domain of the Human Mitochondrial Lon Protease: Proposed Relation of Oligomer Formation and Activity. Protein Sci., 19, 2010
4FWD	Crystal structure of the Lon-like protease MtaLonC in complex with bortezomib 分子名称: N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, PHOSPHATE ION, TTC1975 peptidase 著者 Chang, C.I, Kuo, C.I, Huang, K.F. 登録日 2012-06-30 公開日 2013-06-26 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Structures of an ATP-independent Lon-like protease and its complexes with covalent inhibitors Acta Crystallogr.,Sect.D, 69, 2013
1Z0E	Crystal Structure of A. fulgidus Lon proteolytic domain 分子名称: Putative protease La homolog type 著者 Botos, I, Melnikov, E.E, Cherry, S, Kozlov, S, Makhovskaya, O.V, Tropea, J.E, Gustchina, A, Rotanova, T.V, Wlodawer, A. 登録日 2005-03-01 公開日 2005-08-02 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Atomic-resolution Crystal Structure of the Proteolytic Domain of Archaeoglobus fulgidus Lon Reveals the Conformational Variability in the Active Sites of Lon Proteases J.Mol.Biol., 351, 2005
7EV6	Crystal structure of the Lon-like protease MtaLonC with D581A mutation in complex with F-b20-Q 分子名称: Endopeptidase La, F-b20-Q peptide {ortho-aminobenzoic acid (Abz)- QLRSLNGEWRFAWFPAPEAV[Tyr(3-NO2)]A}, PHOSPHATE ION 著者 Hsieh, K.Y, Kuo, C.I, Su, S.C, Huang, K.F, Chang, C.I. 登録日 2021-05-20 公開日 2021-11-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex. Sci Adv, 7, 2021
1RR9	Catalytic domain of E.coli Lon protease 分子名称: ATP-dependent protease La, SULFATE ION 著者 Botos, I, Melnikov, E.E, Cherry, S, Tropea, J.E, Khalatova, A.G, Dauter, Z, Maurizi, M.R, Rotanova, T.V, Wlodawer, A, Gustchina, A. 登録日 2003-12-08 公開日 2003-12-23 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The catalytic domain of Escherichia coli Lon protease has a unique fold and a Ser-Lys dyad in the active site J.Biol.Chem., 279, 2004
7EV4	Crystal structure of the Lon-like protease MtaLonC with S582A mutation in complex with F-b20-Q 分子名称: Endopeptidase La, F-b20-Q peptide {ortho-aminobenzoic acid (Abz)- QLRSLNGEWRFAWFPAPEAV[Tyr(3-NO2)]A}, PHOSPHATE ION 著者 Hsieh, K.Y, Kuo, C.I, Su, S.C, Huang, K.F, Chang, C.I. 登録日 2021-05-20 公開日 2021-11-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex. Sci Adv, 7, 2021
6X27	Lon protease proteolytic domain complexed with bortezomib 分子名称: GLYCEROL, Lon protease homolog, mitochondrial, ... 著者 Lee, C.C, Spraggon, G. 登録日 2020-05-20 公開日 2021-04-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Structure-Based Design of Selective LONP1 Inhibitors for Probing In Vitro Biology. J.Med.Chem., 64, 2021
4FWH	Crystal structure of the Lon-like protease MtaLonC in complex with MG262 分子名称: N-[(benzyloxy)carbonyl]-L-leucyl-N-[(1R)-1-(dihydroxyboranyl)-3-methylbutyl]-L-leucinamide, PHOSPHATE ION, TTC1975 peptidase 著者 Chang, C.I, Kuo, C.I, Huang, K.F. 登録日 2012-07-01 公開日 2013-06-26 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Structures of an ATP-independent Lon-like protease and its complexes with covalent inhibitors Acta Crystallogr.,Sect.D, 69, 2013
7EUY	Crystal structure of the Lon-like protease MtaLonC with D582A mutation in complex with substrate polypeptide 分子名称: ALA-PRO-GLU-ALA-VAL, Endopeptidase La, PHOSPHATE ION 著者 Hsieh, K.Y, Kuo, C.I, Su, S.C, Huang, K.F, Chang, C.I. 登録日 2021-05-19 公開日 2021-11-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex. Sci Adv, 7, 2021
6WYS	Lon protease proteolytic domain 分子名称: Lon protease homolog, mitochondrial, SULFATE ION 著者 Lee, C.C, Spraggon, G. 登録日 2020-05-13 公開日 2021-04-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.229 Å) 主引用文献 Structure-Based Design of Selective LONP1 Inhibitors for Probing In Vitro Biology. J.Med.Chem., 64, 2021
8EIL	C-Terminal Domain of BrxL from Acinetobacter BREX type I phage restriction system 分子名称: MALONIC ACID, Protease Lon-related BREX system protein BrxL, SUCCINIC ACID 著者 Doyle, L.A, Stoddard, B.L, Kaiser, B. 登録日 2022-09-15 公開日 2023-02-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure, substrate binding and activity of a unique AAA+ protein: the BrxL phage restriction factor. Nucleic Acids Res., 51, 2023
7EUX	Crystal structure of the Lon-like protease MtaLonC with D581A mutation in complex with substrate polypeptide 分子名称: ALA-PRO-GLU-ALA-VAL, Endopeptidase La, PHOSPHATE ION 著者 Hsieh, K.Y, Kuo, C.I, Su, S.C, Huang, K.F, Chang, C.I. 登録日 2021-05-19 公開日 2021-11-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex. Sci Adv, 7, 2021
1Z0G	Crystal Structure of A. fulgidus Lon proteolytic domain 分子名称: Putative protease La homolog type 著者 Botos, I, Melnikov, E.E, Cherry, S, Kozlov, S, Makhovskaya, O.V, Tropea, J.E, Gustchina, A, Rotanova, T.V, Wlodawer, A. 登録日 2005-03-01 公開日 2005-08-02 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Atomic-resolution Crystal Structure of the Proteolytic Domain of Archaeoglobus fulgidus Lon Reveals the Conformational Variability in the Active Sites of Lon Proteases J.Mol.Biol., 351, 2005
7FIE	Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex (conformation 2) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... 著者 Li, S, Hsieh, K, Kuo, C, Su, S, Huang, K, Zhang, K, Chang, C.I. 登録日 2021-07-31 公開日 2021-11-24 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (2.36 Å) 主引用文献 Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex. Sci Adv, 7, 2021
7FD4	A complete three-dimensional structure of the Lon protease translocating a protein substrate (conformation 1) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Alpha-S1-casein, Lon protease, ... 著者 Li, S, Hsieh, K, Kuo, C, Lee, S, Pintilie, G, Zhang, K, Chang, C. 登録日 2021-07-16 公開日 2021-11-03 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Complete three-dimensional structures of the Lon protease translocating a protein substrate. Sci Adv, 7, 2021

 

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