8YJX
 
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8VBT
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8VBU
 | | Structure of the monofunctional Staphylococcus aureus PBP1 in its beta-lactam (Oxacillin) inhibited form | | 分子名称: | (2R,4S)-5,5-dimethyl-2-[(1R)-1-{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}-2-oxoethyl]-1,3-thiazolidine-4-carb oxylic acid, Penicillin-binding protein 1 | | 著者 | Bon, C.G, Lee, J, Caveney, N.A, Strynadka, N.C.J. | | 登録日 | 2023-12-12 | | 公開日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1.
J.Struct.Biol., 216, 2024
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8VBW
 | | Structure of the monofunctional Staphylococcus aureus PBP1 in its beta-lactam (Ertapenem) inhibited form | | 分子名称: | (4R,5S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, Penicillin-binding protein 1 | | 著者 | Bon, C.G, Lee, J, Caveney, N.A, Strynadka, N.C.J. | | 登録日 | 2023-12-12 | | 公開日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1.
J.Struct.Biol., 216, 2024
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8VBV
 | | Structure of the monofunctional Staphylococcus aureus PBP1 in its beta-lactam (Cephalexin) inhibited form | | 分子名称: | (2S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5-methyl-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Penicillin-binding protein 1 | | 著者 | Bon, C.G, Lee, J, Caveney, N.A, Strynadka, N.C.J. | | 登録日 | 2023-12-12 | | 公開日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1.
J.Struct.Biol., 216, 2024
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8U55
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8TJ3
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8P1U
 | | Structure of divisome complex FtsWIQLB | | 分子名称: | Cell division protein FtsB, Cell division protein FtsL, Cell division protein FtsQ, ... | | 著者 | Yang, L, Chang, S, Tang, D, Dong, H. | | 登録日 | 2023-05-12 | | 公開日 | 2024-05-22 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural insights into the activation of the divisome complex FtsWIQLB.
Cell Discov, 10, 2024
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8C5W
 | | Crystal Structure of Penicillin-binding Protein 3 (PBP3) from Staphylococcus Epidermidis in complex with Cefotaxime | | 分子名称: | CEFOTAXIME, C3' cleaved, open, ... | | 著者 | Schwinzer, M, Brognaro, H, Rohde, H, Betzel, C. | | 登録日 | 2023-01-10 | | 公開日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Structure and Dynamics of the Penicillin-Binding Protein 3 from Staphylococcus Epidermidis Native and in Complex with Cefotaxime and Vaborbactam
Int J Appl Biol Pharm, 2023
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8C5O
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8C5B
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8F67
 | | Crystal structure of the refolded Penicillin Binding Protein 5 (PBP5) of Enterococcus faecium | | 分子名称: | Pbp5, SULFATE ION | | 著者 | D'Andrea, E.D, Schoenle, M.V, Choy, M.S, Peti, W, Page, R. | | 登録日 | 2022-11-16 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.59 Å) | | 主引用文献 | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
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8F3H
 | | Crystal structure of Penicillin Binding Protein 5 (PBP5) S466 insertion variant apo form from Enterococcus faecium | | 分子名称: | Penicillin binding protein 5, SULFATE ION | | 著者 | D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. | | 登録日 | 2022-11-10 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
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8F3L
 | | Crystal structure of Penicillin Binding Protein 5 (PBP5) T485A variant penicillin bound form from Enterococcus faecium | | 分子名称: | OPEN FORM - PENICILLIN G, Penicillin binding protein 5, SULFATE ION | | 著者 | D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. | | 登録日 | 2022-11-10 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
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8F3O
 | | Crystal structure of Penicillin Binding Protein 5 (PBP5) R464A variant apo form from Enterococcus faecium | | 分子名称: | Penicillin binding protein 5, SULFATE ION | | 著者 | D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Peti, W, Page, R. | | 登録日 | 2022-11-10 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
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8F3S
 | | Crystal structure of Penicillin Binding Protein 5 (PBP5) T485M T499I variant penicillin bound form from Enterococcus faecium | | 分子名称: | OPEN FORM - PENICILLIN G, Penicillin binding protein 5, SULFATE ION | | 著者 | D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. | | 登録日 | 2022-11-10 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
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8F3T
 | | Crystal structure of Penicillin Binding Protein 5 (PBP5) T485M T499I V629E variant apo form from Enterococcus faecium | | 分子名称: | Penicillin binding protein 5, SODIUM ION, SULFATE ION | | 著者 | D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. | | 登録日 | 2022-11-10 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
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8F3I
 | | Crystal structure of Penicillin Binding Protein 5 (PBP5) S466 insertion variant penicillin bound form from Enterococcus faecium | | 分子名称: | OPEN FORM - PENICILLIN G, Penicillin binding protein 5, SULFATE ION | | 著者 | D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. | | 登録日 | 2022-11-10 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
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8F3Z
 | | Crystal structure of Penicillin Binding Protein 5 (PBP5) S422A variant apo form from Enterococcus faecium | | 分子名称: | Penicillin binding protein 5, SULFATE ION | | 著者 | Schoenle, M.V, D'Andrea, E.D, Choy, M.S, Peti, W, Page, R. | | 登録日 | 2022-11-10 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
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8F3U
 | | Crystal structure of Penicillin Binding Protein 5 (PBP5) T485M T499I V629E variant penicillin bound form from Enterococcus faecium | | 分子名称: | OPEN FORM - PENICILLIN G, Penicillin binding protein 5, SULFATE ION | | 著者 | D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. | | 登録日 | 2022-11-10 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
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8F3N
 | | Crystal structure of Penicillin Binding Protein 5 (PBP5) T485A variant with S466 insertion penicillin bound form from Enterococcus faecium | | 分子名称: | OPEN FORM - PENICILLIN G, Penicillin binding protein 5, SULFATE ION | | 著者 | D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. | | 登録日 | 2022-11-10 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
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8F3F
 | | Crystal structure of Penicillin Binding Protein 5 (PBP5) T485M variant apo form from Enterococcus faecium | | 分子名称: | Penicillin binding protein 5, SULFATE ION | | 著者 | D'Andrea, E.D, Choy, M.S, Hunashal, Y, Schoenle, M.V, Page, R, Peti, W. | | 登録日 | 2022-11-10 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
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8F3R
 | | Crystal structure of Penicillin Binding Protein 5 (PBP5) T485M T499I variant apo form from Enterococcus faecium | | 分子名称: | Penicillin binding protein 5, SULFATE ION | | 著者 | D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. | | 登録日 | 2022-11-10 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
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8F3P
 | | Crystal structure of Penicillin Binding Protein 5 (PBP5) R464A variant penicillin bound form from Enterococcus faecium | | 分子名称: | OPEN FORM - PENICILLIN G, Penicillin binding protein 5, SULFATE ION | | 著者 | D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. | | 登録日 | 2022-11-10 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | | 主引用文献 | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
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8F3J
 | | Crystal structure of Penicillin Binding Protein 5 (PBP5) T485A variant apo form from Enterococcus faecium | | 分子名称: | Penicillin binding protein 5, SULFATE ION | | 著者 | D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. | | 登録日 | 2022-11-10 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
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