Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6V5A
DownloadVisualize
BU of 6v5a by Molmil
Crystal structure of the human BK channel gating ring L390P mutant
分子名称: CALCIUM ION, Calcium-activated potassium channel subunit alpha-1, SULFATE ION
著者Deng, Z, Yuan, P.
登録日2019-12-03
公開日2020-07-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Coupling of Ca2+and voltage activation in BK channels through the alpha B helix/voltage sensor interface.
Proc.Natl.Acad.Sci.USA, 117, 2020
7PXE
DownloadVisualize
BU of 7pxe by Molmil
Ca2+ bound Drosophila Slo channel
分子名称: (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, CALCIUM ION, CHOLESTEROL, ...
著者Raisch, T, Brockmann, A, Ebbinghaus-Kintscher, U, Freigang, J, Gutbrod, O, Kubicek, J, Maertens, B, Hofnagel, O, Raunser, S.
登録日2021-10-08
公開日2021-12-15
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.38 Å)
主引用文献Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM.
Nat Commun, 12, 2021
8S3E
DownloadVisualize
BU of 8s3e by Molmil
Structure of rabbit Slo1 in complex with gamma1/LRRC26
分子名称: (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, CALCIUM ION, CHOLESTEROL, ...
著者Redhardt, M, Raunser, S, Raisch, T.
登録日2024-02-20
公開日2024-04-10
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.39 Å)
主引用文献Cryo-EM structure of the Slo1 potassium channel with the auxiliary gamma 1 subunit suggests a mechanism for depolarization-independent activation.
Febs Lett., 598, 2024
7PXH
DownloadVisualize
BU of 7pxh by Molmil
Emodepside-bound Drosophila Slo channel
分子名称: (3~{S},6~{R},9~{S},12~{R},15~{S},18~{R},21~{S},24~{R})-4,6,10,16,18,22-hexamethyl-3,9,15,21-tetrakis(2-methylpropyl)-12,24-bis[(4-morpholin-4-ylphenyl)methyl]-1,7,13,19-tetraoxa-4,10,16,22-tetrazacyclotetracosane-2,5,8,11,14,17,20,23-octone, (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, CALCIUM ION, ...
著者Raisch, T, Brockmann, A, Ebbinghaus-Kintscher, U, Freigang, J, Gutbrod, O, Kubicek, J, Maertens, B, Hofnagel, O, Raunser, S.
登録日2021-10-08
公開日2021-12-15
最終更新日2021-12-22
実験手法ELECTRON MICROSCOPY (2.59 Å)
主引用文献Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM.
Nat Commun, 12, 2021
8HK6
DownloadVisualize
BU of 8hk6 by Molmil
potassium channel
分子名称: POTASSIUM ION, Potassium channel subfamily T member 1, ZINC ION
著者Jiang, D.H, Zhang, J.T.
登録日2022-11-25
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (2.64 Å)
主引用文献Structural basis of human Slo2.2 channel gating and modulation.
Cell Rep, 42, 2023
8HKF
DownloadVisualize
BU of 8hkf by Molmil
ion channel
分子名称: POTASSIUM ION, Potassium channel subfamily T member 1, ZINC ION
著者Jiang, D.H, Zhang, Z.T.
登録日2022-11-25
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (2.66 Å)
主引用文献Structural basis of human Slo2.2 channel gating and modulation.
Cell Rep, 42, 2023
7PXF
DownloadVisualize
BU of 7pxf by Molmil
Ca2+ free Drosophila Slo channel
分子名称: Isoform J of Calcium-activated potassium channel slowpoke, MAGNESIUM ION, POTASSIUM ION
著者Raisch, T, Brockmann, A, Ebbinghaus-Kintscher, U, Freigang, J, Gutbrod, O, Kubicek, J, Maertens, B, Hofnagel, O, Raunser, S.
登録日2021-10-08
公開日2021-12-15
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM.
Nat Commun, 12, 2021
8GHF
DownloadVisualize
BU of 8ghf by Molmil
cryo-EM structure of hSlo1 in plasma membrane vesicles
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, CHOLESTEROL, ...
著者Tao, X, Zhao, C, MacKinnon, R.
登録日2023-03-10
公開日2023-05-10
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Membrane protein isolation and structure determination in cell-derived membrane vesicles.
Proc.Natl.Acad.Sci.USA, 120, 2023
7PXG
DownloadVisualize
BU of 7pxg by Molmil
Verruculogen-bound Drosophila Slo channel
分子名称: (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, CALCIUM ION, CHOLESTEROL, ...
著者Raisch, T, Brockmann, A, Ebbinghaus-Kintscher, U, Freigang, J, Gutbrod, O, Kubicek, J, Maertens, B, Hofnagel, O, Raunser, S.
登録日2021-10-08
公開日2021-12-15
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM.
Nat Commun, 12, 2021
8HKK
DownloadVisualize
BU of 8hkk by Molmil
ion channel
分子名称: POTASSIUM ION, Potassium channel subfamily T member 1, SODIUM ION, ...
著者Jiang, D.H, Zhang, J.T.
登録日2022-11-27
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (2.84 Å)
主引用文献Structural basis of human Slo2.2 channel gating and modulation.
Cell Rep, 42, 2023
8HKQ
DownloadVisualize
BU of 8hkq by Molmil
ion channel
分子名称: POTASSIUM ION, Potassium channel subfamily T member 1, SODIUM ION, ...
著者Jiang, D.H, Zhang, J.T.
登録日2022-11-27
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of human Slo2.2 channel gating and modulation.
Cell Rep, 42, 2023
7RK6
DownloadVisualize
BU of 7rk6 by Molmil
Aplysia Slo1 with Barium
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, BARIUM ION, BK channel, ...
著者Zhu, J, Srivastava, S, Cachau, R, Holmgren, M.
登録日2021-07-22
公開日2022-06-22
最終更新日2023-04-05
実験手法ELECTRON MICROSCOPY (2.91 Å)
主引用文献CryoEM structure of Aplysia Slo1 with 0 mM Ba2+ at 2.91 A
To Be Published
7RJT
DownloadVisualize
BU of 7rjt by Molmil
Aplysia Slo1 with Barium
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, BARIUM ION, BK channel, ...
著者Zhu, J, Srivastava, S, Cachau, R, Holmgren, M.
登録日2021-07-21
公開日2022-06-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献CryoEM structure of Aplysia Slo1 with 10 mM Ba2+ at 2.93 A
To Be Published
8HKM
DownloadVisualize
BU of 8hkm by Molmil
ion channel
分子名称: POTASSIUM ION, Potassium channel subfamily T member 1, ZINC ION, ...
著者Jiang, D.H, Zhang, J.T.
登録日2022-11-27
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Structural basis of human Slo2.2 channel gating and modulation.
Cell Rep, 42, 2023
3MT5
DownloadVisualize
BU of 3mt5 by Molmil
Crystal Structure of the Human BK Gating Apparatus
分子名称: CALCIUM ION, Potassium large conductance calcium-activated channel, subfamily M, ...
著者Yuan, P, MacKinnon, R.
登録日2010-04-30
公開日2010-06-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the human BK channel Ca2+-activation apparatus at 3.0 A resolution.
Science, 329, 2010
7YO3
DownloadVisualize
BU of 7yo3 by Molmil
Cryo-EM structure of human Slo1-LRRC26 complex with C4 symmetry
分子名称: CALCIUM ION, Calcium-activated potassium channel subunit alpha-1, Leucine-rich repeat-containing protein 26, ...
著者Yamanouchi, D, Nureki, O.
登録日2022-08-01
公開日2023-08-30
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for dual allosteric gating modulation of Slo1-LRRC channel complex
To Be Published
3NAF
DownloadVisualize
BU of 3naf by Molmil
Structure of the Intracellular Gating Ring from the Human High-conductance Ca2+ gated K+ Channel (BK Channel)
分子名称: Calcium-activated potassium channel subunit alpha-1,Calcium-activated potassium channel subunit alpha-1,Calcium-activated potassium channel subunit alpha-1
著者Wu, Y, Yang, Y, Ye, S, Jiang, Y.
登録日2010-06-01
公開日2010-06-30
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of the gating ring from the human large-conductance Ca(2+)-gated K(+) channel.
Nature, 466, 2010
8HIR
DownloadVisualize
BU of 8hir by Molmil
potassium channels
分子名称: POTASSIUM ION, Potassium channel subfamily T member 1, SODIUM ION, ...
著者Jiang, D.H, Zhang, J.T.
登録日2022-11-21
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Structural basis of human Slo2.2 channel gating and modulation.
Cell Rep, 42, 2023
6V22
DownloadVisualize
BU of 6v22 by Molmil
Cryo-EM structure of Ca2+-bound hsSlo1-beta4 channel complex
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Tao, X, MacKinnon, R.
登録日2019-11-22
公開日2019-12-25
最終更新日2020-10-07
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Molecular structures of the human Slo1 K + channel in complex with beta 4.
Elife, 8, 2019
7YO2
DownloadVisualize
BU of 7yo2 by Molmil
Cryo-EM structure of RCK1-RCK2 mutated human Slo1 apo
分子名称: Calcium-activated potassium channel subunit alpha-1
著者Yamanouchi, D, Nureki, O.
登録日2022-08-01
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for dual allosteric gating modulation of Slo1-LRRC channel complex
To Be Published
8GHG
DownloadVisualize
BU of 8ghg by Molmil
Cryo-EM structure of hSlo1 in digitonin, Ca2+-free and EDTA-free
分子名称: Calcium-activated potassium channel subunit alpha-1
著者Tao, X, Zhao, C, MacKinnon, R.
登録日2023-03-10
公開日2023-05-10
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Membrane protein isolation and structure determination in cell-derived membrane vesicles.
Proc.Natl.Acad.Sci.USA, 120, 2023
4HPF
DownloadVisualize
BU of 4hpf by Molmil
Structure of the human SLO3 gating ring
分子名称: Potassium channel subfamily U member 1
著者Leonetti, M.D, Yuan, P, MacKinnon, R.
登録日2012-10-23
公開日2012-11-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Functional and structural analysis of the human SLO3 pH- and voltage-gated K+ channel.
Proc.Natl.Acad.Sci.USA, 109, 2012
7YNZ
DownloadVisualize
BU of 7ynz by Molmil
Cryo-EM structure of human Slo1-LRRC26 complex with C1 symmetry
分子名称: CALCIUM ION, Calcium-activated potassium channel subunit alpha-1, Leucine-rich repeat-containing protein 26, ...
著者Yamanouchi, D, Nureki, O.
登録日2022-08-01
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis for dual allosteric gating modulation of Slo1-LRRC channel complex
To Be Published
6ND0
DownloadVisualize
BU of 6nd0 by Molmil
human BK channel reconstituted into liposomes
分子名称: Calcium-activated potassium channel subunit alpha-1
著者Wang, L, Tonggu, L.
登録日2018-12-13
公開日2020-06-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Broken symmetry in the human BK channel
To Be Published
6V35
DownloadVisualize
BU of 6v35 by Molmil
Cryo-EM structure of Ca2+-free hsSlo1-beta4 channel complex
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ...
著者Tao, X, MacKinnon, R.
登録日2019-11-25
公開日2019-12-25
最終更新日2020-10-07
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Molecular structures of the human Slo1 K + channel in complex with beta 4.
Elife, 8, 2019

 

12>

226262

件を2024-10-16に公開中

PDB statisticsPDBj update infoContact PDBjnumon