PDB: 43 件ウェブページステータス検索Chemie searchBIRD

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1OTF	4-OXALOCROTONATE TAUTOMERASE-TRICLINIC CRYSTAL FORM 分子名称: 4-OXALOCROTONATE TAUTOMERASE 著者 Subramanya, H.S, Roper, D.I, Dauter, Z, Dodson, E.J, Davies, G.J, Wilson, K.S, Wigley, D.B. 登録日 1995-11-09 公開日 1996-04-03 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Enzymatic ketonization of 2-hydroxymuconate: specificity and mechanism investigated by the crystal structures of two isomerases. Biochemistry, 35, 1996
1S0Y	The structure of trans-3-chloroacrylic acid dehalogenase, covalently inactivated by the mechanism-based inhibitor 3-bromopropiolate at 2.3 Angstrom resolution 分子名称: MALONIC ACID, alpha-subunit of trans-3-chloroacrylic acid dehalogenase, beta-subunit of trans-3-chloroacrylic acid dehalogenase 著者 de Jong, R.M, Brugman, W, Poelarends, G.J, Whitman, C.P, Dijkstra, B.W. 登録日 2004-01-05 公開日 2004-02-24 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The X-ray structure of trans-3-chloroacrylic acid dehalogenase reveals a novel hydration mechanism in the tautomerase superfamily J.Biol.Chem., 279, 2004
4OTC	4-OXALOCROTONATE TAUTOMERASE OBSERVED AS AN OCTODECAMER, TRIGONAL CRYSTAL FORM 分子名称: 4-OXALOCROTONATE TAUTOMERASE, SULFATE ION 著者 Taylor, A.B, Whitman, C.P, Hackert, M.L. 登録日 1998-10-15 公開日 2001-08-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Native and inhibitor complex structures of 4-oxalocrotonate tautomerase from Pseudomonas putida mt-2 (University of Texas at Austin-136 pages) Thesis, 1998
1BJP	CRYSTAL STRUCTURE OF 4-OXALOCROTONATE TAUTOMERASE INACTIVATED BY 2-OXO-3-PENTYNOATE AT 2.4 ANGSTROMS RESOLUTION 分子名称: 2-OXO-3-PENTENOIC ACID, 4-OXALOCROTONATE TAUTOMERASE 著者 Taylor, A.B, Czerwinski, R.M, Johnson Junior, W.H, Whitman, C.P, Hackert, M.L. 登録日 1998-06-26 公開日 1998-12-02 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of 4-oxalocrotonate tautomerase inactivated by 2-oxo-3-pentynoate at 2.4 A resolution: analysis and implications for the mechanism of inactivation and catalysis. Biochemistry, 37, 1998
2X4K	Crystal structure of SAR1376, a putative 4-oxalocrotonate tautomerase from the methicillin-resistant Staphylococcus aureus (MRSA) 分子名称: 4-OXALOCROTONATE TAUTOMERASE, ACETATE ION, PHOSPHATE ION, ... 著者 Oke, M, Carter, L.G, Johnson, K.A, Liu, H, Mcmahon, S.A, White, M.F, Naismith, J.H. 登録日 2010-02-01 公開日 2010-07-21 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 The Scottish Structural Proteomics Facility: Targets, Methods and Outputs. J.Struct.Funct.Genomics, 11, 2010
6OGM	Crystal structure of apo unFused 4-OT 分子名称: 4-oxalocrotonate tautomerase, GLYCEROL 著者 Medellin, B.P, Whitman, C.P, Zhang, Y.J. 登録日 2019-04-03 公開日 2020-02-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.865 Å) 主引用文献 Structural, Kinetic, and Mechanistic Analysis of an Asymmetric 4-Oxalocrotonate Tautomerase Trimer. Biochemistry, 58, 2019
7M59	Crystal structure of N2, a member of 4-oxalocrotonate tautomerase (4-OT) family 分子名称: Tautomerase domain-containing protein 著者 Medellin, B.P, Moreno, R.Y, Zhang, Y.J. 登録日 2021-03-23 公開日 2021-06-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Kinetic and Structural Analysis of Two Linkers in the Tautomerase Superfamily: Analysis and Implications. Biochemistry, 60, 2021
3RY0	Crystal structure of TomN, a 4-Oxalocrotonate Tautomerase homologue in Tomaymycin biosynthetic pathway 分子名称: Putative tautomerase 著者 Zhang, Y, Yan, W.P, Li, W.Z, Whitman, C.P. 登録日 2011-05-10 公開日 2011-08-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Kinetic, Crystallographic, and Mechanistic Characterization of TomN: Elucidation of a Function for a 4-Oxalocrotonate Tautomerase Homologue in the Tomaymycin Biosynthetic Pathway. Biochemistry, 50, 2011
7XUY	Crystal structure of 5-chloro-2-hydroxymuconate tautomerase CnbG 分子名称: Tautomerase 著者 Ma, H.L, Li, D.F. 登録日 2022-05-20 公開日 2023-03-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 Structural insights into the substrate specificity of 5-chloro-2-hydroxymuconate tautomerase CnbG. Biochem.Biophys.Res.Commun., 620, 2022
6GHW	Substituting the prolines of 4-oxalocrotonate tautomerase with non-canonical analogue (2S)-3,4-dehydroproline 分子名称: 2-hydroxymuconate tautomerase, CALCIUM ION 著者 Pavkov-Keller, T, Lukesch, M.S, Wiltschi, B, Gruber, K. 登録日 2018-05-09 公開日 2019-03-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Substituting the catalytic proline of 4-oxalocrotonate tautomerase with non-canonical analogues reveals a finely tuned catalytic system. Sci Rep, 9, 2019
6FPS	Crystal structure of 4-oxalocrotonate tautomerase triple mutant L8Y/M45Y/F50A 分子名称: 2-hydroxymuconate tautomerase, GLYCEROL, PHOSPHATE ION 著者 Pijning, T, Thunnissen, A.M.W.H. 登録日 2018-02-12 公開日 2019-03-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Enantioselective Synthesis of Pharmaceutically Active gamma-Aminobutyric Acids Using a Tailor-Made Artificial Michaelase in One-Pot Cascade Reactions. ACS Catal, 9, 2019
7PUO	Structure of a fused 4-OT variant engineered for asymmetric Michael addition reactions 分子名称: 2-hydroxymuconate tautomerase,Chains: A,B,C,D,E,F,2-hydroxymuconate tautomerase, CHLORIDE ION, GLYCEROL 著者 Rozeboom, H.J, Thunnissen, A.M.W.H, Poelarends, G.J. 登録日 2021-09-30 公開日 2022-01-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Gene Fusion and Directed Evolution to Break Structural Symmetry and Boost Catalysis by an Oligomeric C-C Bond-Forming Enzyme. Angew.Chem.Int.Ed.Engl., 61, 2022
2FM7	Evolution of Enzymatic Activity in the Tautomerase Superfamily: Mechanistic and Structural Consequences of the L8R Mutation in 4-Oxalocrotonate Tautomerase 分子名称: 4-Oxalocrotonate Tautomerase, CHLORIDE ION 著者 Almrud, J.J, Hackert, M.L. 登録日 2006-01-08 公開日 2006-09-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Evolution of enzymatic activity in the tautomerase superfamily: mechanistic and structural consequences of the L8R mutation in 4-oxalocrotonate tautomerase Biochemistry, 45, 2006
3ABF	Crystal Structure of a 4-Oxalocrotonate Tautomerase Homologue (TTHB242) 分子名称: 4-oxalocrotonate tautomerase, SULFATE ION 著者 Kida, H, Miki, K. 登録日 2009-12-10 公開日 2010-12-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Crystal Structure of a 4-Oxalocrotonate Tautomerase Homologue (TTHB242) from Thermus thermophilus HB8 To be Published
3M20	Crystal structure of DmpI from Archaeoglobus fulgidus determined to 2.37 Angstroms resolution 分子名称: 4-oxalocrotonate tautomerase, putative 著者 Hackert, M.L, Whitman, C.P, Almrud, J.J, Dasgupta, R, Kern, A.D. 登録日 2010-03-06 公開日 2010-09-01 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Kinetic and structural characterization of DmpI from Helicobacter pylori and Archaeoglobus fulgidus, two 4-oxalocrotonate tautomerase family members. Bioorg.Chem., 38, 2010
3M21	Crystal structure of DmpI from Helicobacter pylori Determined to 1.9 Angstroms resolution 分子名称: Probable tautomerase HP_0924 著者 Hackert, M.L, Whitman, C.P, Almrud, J.J, Dasgupta, R, Kern, A.D, Czerwinski, R.M. 登録日 2010-03-06 公開日 2010-09-01 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Kinetic and structural characterization of DmpI from Helicobacter pylori and Archaeoglobus fulgidus, two 4-oxalocrotonate tautomerase family members. Bioorg.Chem., 38, 2010
4X19	Crystal structure of native 4-OT from Pseudomonas putida mt-2 at 1.94 Angstrom 分子名称: 2-hydroxymuconate tautomerase, COBALT HEXAMMINE(III) 著者 Thunnissen, A.M.W.H, Poddar, H. 登録日 2014-11-24 公開日 2015-03-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.944 Å) 主引用文献 Evidence for the Formation of an Enamine Species during Aldol and Michael-type Addition Reactions Promiscuously Catalyzed by 4-Oxalocrotonate Tautomerase. Chembiochem, 16, 2015
5CLO	Crystal structure of a 4-oxalocrotonate tautomerase mutant in complex with nitrostyrene at 2.3 Angstrom 分子名称: 2-hydroxymuconate tautomerase, trans beta nitrostyrene 著者 Thunnissen, A.M.W.H, Poddar, H. 登録日 2015-07-16 公開日 2016-03-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Using mutability landscapes of a promiscuous tautomerase to guide the engineering of enantioselective Michaelases. Nat Commun, 7, 2016
5TIG	CRYSTAL STRUCTURE OF 4-OXALOCROTONATE TAUTOMERASE INACTIVATED BY BrHPD 分子名称: (3E)-5-hydroxy-2-oxopent-3-enoic acid, 2-hydroxymuconate tautomerase 著者 Zhang, Y, Li, W, Stack, T. 登録日 2016-10-02 公開日 2018-02-21 最終更新日 2019-04-17 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Inactivation of 4-Oxalocrotonate Tautomerase by 5-Halo-2-hydroxy-2,4-pentadienoates. Biochemistry, 57, 2018
5CLN	Crystal structure of a 4-oxalocrotonate tautomerase mutant at 2.7 Angstrom 分子名称: 2-hydroxymuconate tautomerase 著者 Thunnissen, A.M.W.H, Poddar, H. 登録日 2015-07-16 公開日 2016-03-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Using mutability landscapes of a promiscuous tautomerase to guide the engineering of enantioselective Michaelases. Nat Commun, 7, 2016
6BGN	Crystal Structure of 4-Oxalocrotonate Tautomerase After Incubation with 5-Fluoro-2-hydroxy-2,4-pentadienoate 分子名称: 2-hydroxymuconate tautomerase, 5-fluoranyl-2-oxidanylidene-pentanoic acid, GLYCEROL, ... 著者 Zhang, Y, Li, W, Stack, T. 登録日 2017-10-29 公開日 2018-02-21 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Inactivation of 4-Oxalocrotonate Tautomerase by 5-Halo-2-hydroxy-2,4-pentadienoates. Biochemistry, 57, 2018
4X1C	Crystal structure of 4-OT from Pseudomonas putida mt-2 with an enamine adduct on the N-terminal proline at 1.7 Angstrom resolution 分子名称: 2-hydroxymuconate tautomerase, COBALT HEXAMMINE(III) 著者 Thunnissen, A.M.W.H, Poddar, H. 登録日 2014-11-24 公開日 2015-03-11 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Evidence for the Formation of an Enamine Species during Aldol and Michael-type Addition Reactions Promiscuously Catalyzed by 4-Oxalocrotonate Tautomerase. Chembiochem, 16, 2015
6BLM	Crystal Structure of Native Fused 4-OT 分子名称: 4-oxalocrotonate tautomerase 著者 LeVieux, J, Baas, B.J, Zhang, Y.J, Whitman, C.P. 登録日 2017-11-10 公開日 2017-12-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.488 Å) 主引用文献 A global view of structure-function relationships in the tautomerase superfamily. J. Biol. Chem., 293, 2018
6VVR	Q0 fused 4-OT wild type symmetric trimer 分子名称: Tautomerase 著者 Medellin, B.P, Whitman, C.P, Zhang, Y.J. 登録日 2020-02-18 公開日 2020-04-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Basis for the Asymmetry of a 4-Oxalocrotonate Tautomerase Trimer. Biochemistry, 59, 2020
6VVW	W0 fused 4-OT wild type symmetric trimer 分子名称: Tautomerase 著者 Medellin, B.P, Whitman, C.P, Zhang, Y.J. 登録日 2020-02-18 公開日 2020-04-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Basis for the Asymmetry of a 4-Oxalocrotonate Tautomerase Trimer. Biochemistry, 59, 2020

 

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