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6ZBK
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BU of 6zbk by Molmil
Crystal structure of the human complex between RPAP3 and TRBP
分子名称: RISC-loading complex subunit TARBP2, RNA polymerase II-associated protein 3
著者Charron, C, Abel, Y, Charpentier, B, Rederstorff, M.
登録日2020-06-08
公開日2021-06-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献The interaction between RPAP3 and TRBP reveals a possible involvement of the HSP90/R2TP chaperone complex in the regulation of miRNA activity.
Nucleic Acids Res., 50, 2022
5LYP
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BU of 5lyp by Molmil
Crystal structure of the Tpr Domain of Sgt2.
分子名称: BORATE ION, Small glutamine-rich tetratricopeptide repeat-containing protein 2
著者Krysztofinska, E.M, Morgan, R.M.L, Thapaliya, A, Evans, N.J, Murray, J.W, Martinez-Lumbreras, S, Isaacson, R.L.
登録日2016-09-28
公開日2017-10-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure and Interactions of the TPR Domain of Sgt2 with Yeast Chaperones and Ybr137wp.
Front Mol Biosci, 4, 2017
4GCO
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BU of 4gco by Molmil
Central domain of stress-induced protein-1 (STI-1) from C.elegans
分子名称: Protein STI-1
著者Osipiuk, J, Bigelow, L, Gu, M, Van Oosten-Hawle, P, Morimoto, R.I, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2012-07-30
公開日2012-08-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Central domain of stress-induced protein-1 (STI-1) from C.elegans
To be Published
3UPV
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BU of 3upv by Molmil
TPR2B-domain:pHsp70-complex of yeast Sti1
分子名称: Heat shock protein SSA4, Heat shock protein STI1
著者Schmid, A.B, Lagleder, S, Graewert, M.A, Roehl, A, Hagn, F, Wandinger, S.K, Cox, M.B, Demmer, O, Richter, K, Groll, M, Kessler, H.
登録日2011-11-18
公開日2012-01-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop.
Embo J., 31, 2012
3VTX
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BU of 3vtx by Molmil
Crystal structure of MamA protein
分子名称: GLYCEROL, MamA
著者Zeytuni, N, Baran, D, Davidov, G, Zarivach, R.
登録日2012-06-08
公開日2012-10-31
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Inter-phylum structural conservation of the magnetosome-associated TPR-containing protein, MamA
J.Struct.Biol., 180, 2012
6EOU
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BU of 6eou by Molmil
O-GlcNAc transferase TPR domain with the intellectual disability associated mutation L254F
分子名称: UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
著者Gundogdu, M, van Aalten, D.M.F.
登録日2017-10-10
公開日2018-05-09
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The O-GlcNAc Transferase Intellectual Disability Mutation L254F Distorts the TPR Helix.
Cell Chem Biol, 25, 2018
5JHE
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BU of 5jhe by Molmil
The Crystal Structure of the Saccharomyces cerevisiae Co-Chaperone Cpr7
分子名称: Peptidyl-prolyl cis-trans isomerase CYP7
著者Yu, Q, Xu, L.
登録日2016-04-20
公開日2017-04-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Crystal Structure of the Saccharomyces cerevisiae Co-Chaperone Cpr7
To Be Published
4GCN
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BU of 4gcn by Molmil
N-terminal domain of stress-induced protein-1 (STI-1) from C.elegans
分子名称: Protein STI-1, TRIETHYLENE GLYCOL
著者Osipiuk, J, Bigelow, L, Gu, M, Van Oosten-Hawle, P, Morimoto, R.I, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2012-07-30
公開日2012-08-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献N-terminal domain of stress-induced protein-1 (STI-1) from C.elegans
To be Published
5OMP
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BU of 5omp by Molmil
Human FKBP5 protein
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP5, SULFATE ION
著者Kumar, R, Moche, M, Winblad, B, Pavlov, P.
登録日2017-08-01
公開日2017-11-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Combined x-ray crystallography and computational modeling approach to investigate the Hsp90 C-terminal peptide binding to FKBP51.
Sci Rep, 7, 2017
1ELR
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BU of 1elr by Molmil
Crystal structure of the TPR2A domain of HOP in complex with the HSP90 peptide MEEVD
分子名称: HSP90-PEPTIDE MEEVD, NICKEL (II) ION, TPR2A-DOMAIN OF HOP
著者Scheufler, C, Brinker, A, Hartl, F.U, Moarefi, I.
登録日2000-03-14
公開日2000-04-26
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine.
Cell(Cambridge,Mass.), 101, 2000
3FP2
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BU of 3fp2 by Molmil
Crystal structure of Tom71 complexed with Hsp82 C-terminal fragment
分子名称: ATP-dependent molecular chaperone HSP82, CHLORIDE ION, MAGNESIUM ION, ...
著者Li, J, Qian, X, Hu, J, Sha, B.
登録日2009-01-03
公開日2009-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Molecular chaperone Hsp70/Hsp90 prepares the mitochondrial outer membrane translocon receptor Tom71 for preprotein loading.
J.Biol.Chem., 284, 2009
3FP3
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BU of 3fp3 by Molmil
Crystal structure of Tom71
分子名称: CHLORIDE ION, SULFATE ION, TPR repeat-containing protein YHR117W
著者Li, J, Qian, X, Hu, J, Sha, B.
登録日2009-01-03
公開日2009-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Molecular chaperone Hsp70/Hsp90 prepares the mitochondrial outer membrane translocon receptor Tom71 for preprotein loading.
J.Biol.Chem., 284, 2009
3VTY
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BU of 3vty by Molmil
Crystal structure of MamA
分子名称: CHLORIDE ION, MamA
著者Zeytuni, N, Baran, D, Davidov, G, Zarivach, R.
登録日2012-06-08
公開日2012-10-31
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Inter-phylum structural conservation of the magnetosome-associated TPR-containing protein, MamA
J.Struct.Biol., 180, 2012
5LYN
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BU of 5lyn by Molmil
Structure of the Tpr Domain of Sgt2 in complex with yeast Ssa1 peptide fragment
分子名称: PRO-THR-VAL-GLU-GLU-VAL-ASP, Small glutamine-rich tetratricopeptide repeat-containing protein 2, ZINC ION
著者Krysztofinska, E.M, Evans, N.J, Thapaliya, A, Murray, J.W, Morgan, R.M.L, Martinez-Lumbreras, S, Isaacson, R.L.
登録日2016-09-28
公開日2017-10-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and Interactions of the TPR Domain of Sgt2 with Yeast Chaperones and Ybr137wp.
Front Mol Biosci, 4, 2017
4JA7
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BU of 4ja7 by Molmil
Rat PP5 co-crystallized with P5SA-2
分子名称: MAGNESIUM ION, Serine/threonine-protein phosphatase 5
著者Haslbeck, V, Helmuth, M, Alte, F, Popowicz, G, Schmidt, W, Weiwad, M, Fischer, G, Gemmecker, G, Sattler, M, Striggow, F, Groll, M, Richter, K.
登録日2013-02-18
公開日2014-02-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Selective activators of protein phosphatase 5 target the auto-inhibitory mechanism.
Biosci.Rep., 35, 2015
3ESK
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BU of 3esk by Molmil
Structure of HOP TPR2A domain in complex with the non-cognate Hsc70 peptide ligand
分子名称: Heat shock cognate 71 kDa protein, NICKEL (II) ION, Stress-induced-phosphoprotein 1
著者Kajander, T, Regan, L.
登録日2008-10-06
公開日2009-07-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Electrostatic interactions of Hsp-organizing protein tetratricopeptide domains with Hsp70 and Hsp90: computational analysis and protein engineering.
J.Biol.Chem., 284, 2009
5JJT
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BU of 5jjt by Molmil
Crystal structure of a type 5 serine/threonine protein phosphatase from Arabidopsis thaliana
分子名称: NICKEL (II) ION, Serine/threonine-protein phosphatase 5
著者Li, H.M, Pu, H.
登録日2016-04-25
公開日2017-04-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.103 Å)
主引用文献Crystal structure of a type 5 serine/threonine protein phosphatase from Arabidopsis thaliana
To Be Published
3FP4
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BU of 3fp4 by Molmil
Crystal structure of Tom71 complexed with Ssa1 C-terminal fragment
分子名称: CHLORIDE ION, SODIUM ION, SULFATE ION, ...
著者Li, J, Qian, X, Hu, J, Sha, B.
登録日2009-01-03
公開日2009-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Molecular chaperone Hsp70/Hsp90 prepares the mitochondrial outer membrane translocon receptor Tom71 for preprotein loading.
J.Biol.Chem., 284, 2009
3LCA
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BU of 3lca by Molmil
Structure of Tom71 complexed with Hsp70 Ssa1 C terminal tail indicating conformational plasticity
分子名称: GLYCEROL, Heat shock protein SSA1, Protein TOM71
著者Li, J.Z, Sha, B.D.
登録日2010-01-10
公開日2010-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献The structural plasticity of Tom71 for mitochondrial precursor translocations.
Acta Crystallogr.,Sect.F, 66, 2010
3FWV
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BU of 3fwv by Molmil
Crystal Structure of a Redesigned TPR Protein, T-MOD(VMY), in Complex with MEEVF Peptide
分子名称: Heat shock protein HSP 90-beta, Hsc70/Hsp90-organizing protein, NICKEL (II) ION
著者Jackrel, M.E, Valverde, R, Regan, L.
登録日2009-01-19
公開日2009-04-21
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Redesign of a protein-peptide interaction: characterization and applications
Protein Sci., 18, 2009
7DHG
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BU of 7dhg by Molmil
Crystal structure of SARS-CoV-2 Orf9b complex with human TOM70
分子名称: Mitochondrial import receptor subunit TOM70, ORF9b protein
著者Gao, X, Zhu, K, Qin, B, Olieric, V, Wang, M, Cui, S.
登録日2020-11-14
公開日2021-05-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of SARS-CoV-2 Orf9b in complex with human TOM70 suggests unusual virus-host interactions.
Nat Commun, 12, 2021
5OJ8
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BU of 5oj8 by Molmil
Crystal structure of the KLC1-TPR domain ([A1-B5] fragment)
分子名称: Kinesin light chain 1, PHOSPHATE ION
著者Nguyen, T.Q, Chenon, M, Vilela, F, Velours, C, Fernandez-Varela, P, Llinas, P, Menetrey, J.
登録日2017-07-20
公開日2017-10-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.247 Å)
主引用文献Structural plasticity of the N-terminal capping helix of the TPR domain of kinesin light chain.
PLoS ONE, 12, 2017
6FV0
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BU of 6fv0 by Molmil
Crystal structure of the TPR domain of KLC1 in complex with the C-terminal peptide of torsinA
分子名称: DI(HYDROXYETHYL)ETHER, Kinesin light chain 1,Torsin-1A, nanobody
著者Pernigo, S, Dodding, M.P, Steiner, R.A.
登録日2018-02-28
公開日2018-03-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Structural basis for isoform-specific kinesin-1 recognition of Y-acidic cargo adaptors.
Elife, 7, 2018
4JA9
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BU of 4ja9 by Molmil
Rat PP5 apo
分子名称: MAGNESIUM ION, Serine/threonine-protein phosphatase 5
著者Haslbeck, V, Helmuth, M, Alte, F, Popowicz, G, Schmidt, W, Weiwad, M, Fischer, G, Gemmecker, G, Sattler, M, Striggow, F, Groll, M, Richter, K.
登録日2013-02-18
公開日2014-02-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Selective activators of protein phosphatase 5 target the auto-inhibitory mechanism.
Biosci.Rep., 35, 2015
2VYI
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BU of 2vyi by Molmil
Crystal Structure of the TPR domain of Human SGT
分子名称: SGTA PROTEIN
著者Dutta, S, Tan, Y.J.
登録日2008-07-24
公開日2008-08-12
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and Functional Characterization of Human Sgt and its Interaction with Vpu of the Human Immunodeficiency Virus Type 1.
Biochemistry, 47, 2008

 

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