PDB: 10962 件ウェブページステータス検索Chemie searchBIRD

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3RSF	Crystal structure of tm0922, a fusion of a domain of unknown function and ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Thermotoga maritima in complex with P1,P4-Di(adenosine-5') tetraphosphate 分子名称: BIS(ADENOSINE)-5'-TETRAPHOSPHATE, POTASSIUM ION, Putative uncharacterized protein, ... 著者 Shumilin, I.A, Cymborowski, M, Lesley, S.A, Minor, W. 登録日 2011-05-02 公開日 2011-06-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Identification of unknown protein function using metabolite cocktail screening. Structure, 20, 2012
3W0E	Structure of elastase inhibitor AFUEI (crystal form II) 分子名称: Elastase inhibitor AFUEI 著者 Imada, K, Sakuma, M, Okumura, Y, Ogawa, K, Nikai, T, Homma, M. 登録日 2012-10-29 公開日 2013-05-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 X-ray Structure Analysis and Characterization of AFUEI, an Elastase Inhibitor from Aspergillus fumigatus J.Biol.Chem., 288, 2013
3VV7	Crystal Structure of beta secetase in complex with 2-amino-6-((1S,2R)-2-(3'-methoxybiphenyl-3-yl)cyclopropyl)-3-methylpyrimidin-4(3H)-one 分子名称: 2-amino-6-[(1S,2R)-2-(3'-methoxybiphenyl-3-yl)cyclopropyl]-3-methylpyrimidin-4(3H)-one, Beta-secretase 1, GLYCEROL, ... 著者 Yonezawa, S, Yamamoto, T, Yamakawa, H, Muto, C, Hosono, M, Hattori, K, Higashino, K, Sakagami, M, Togame, H, Tanaka, Y, Nakano, T, Takemoto, H, Arisawa, M, Shuto, S. 登録日 2012-07-17 公開日 2012-10-24 最終更新日 2013-09-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Conformational restriction approach to beta-secretase (BACE1) inhibitors: effect of a cyclopropane ring to induce an alternative binding mode. J.Med.Chem., 55, 2012
3VZV	Crystal structure of human mdm2 with a dihydroimidazothiazole inhibitor 分子名称: 1-{[(5R,6S)-5,6-bis(4-chlorophenyl)-6-methyl-3-(propan-2-yl)-5,6-dihydroimidazo[2,1-b][1,3]thiazol-2-yl]carbonyl}-N,N-dimethyl-L-prolinamide, E3 ubiquitin-protein ligase Mdm2 著者 Shimizu, H, Katakura, S, Miyazaki, M, Naito, H, Sugimoto, Y, Kawato, H, Okayama, T, Soga, T. 登録日 2012-10-16 公開日 2013-02-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Lead optimization of novel p53-MDM2 interaction inhibitors possessing dihydroimidazothiazole scaffold Bioorg.Med.Chem.Lett., 23, 2013
3RTB	Crystal structure of tm0922, a fusion of a domain of unknown function and ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Thermotoga maritima soaked with Adenosine-3'-5'-Diphosphate 分子名称: ADENOSINE-3'-5'-DIPHOSPHATE, GLYCEROL, POTASSIUM ION, ... 著者 Shumilin, I.A, Cymborowski, M, Lesley, S.A, Minor, W. 登録日 2011-05-03 公開日 2011-07-27 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Identification of unknown protein function using metabolite cocktail screening. Structure, 20, 2012
3W5B	Crystal structure of the recombinant SERCA1a (calcium pump of fast twitch skeletal muscle) in the E1.Mg2+ state 分子名称: 2',3'-O-[(1r)-2,4,6-trinitrocyclohexa-2,5-diene-1,1-diyl]adenosine 5'-(dihydrogen phosphate), MAGNESIUM ION, PHOSPHATIDYLETHANOLAMINE, ... 著者 Toyoshima, C, Iwasawa, S, Ogawa, H, Hirata, A, Tsueda, J, Inesi, G. 登録日 2013-01-27 公開日 2013-03-06 最終更新日 2013-03-27 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structures of the calcium pump and sarcolipin in the Mg2+-bound E1 state. Nature, 495, 2013
3W69	Crystal structure of human mdm2 with a dihydroimidazothiazole inhibitor 分子名称: (5R,6S)-2-[((2S,5R)-2-{[(3R)-4-acetyl-3-methylpiperazin-1-yl]carbonyl}-5-ethylpyrrolidin-1-yl)carbonyl]-5,6-bis(4-chlorophenyl)-3-isopropyl-6-methyl-5,6-dihydroimidazo[2,1-b][1,3]thiazole, E3 ubiquitin-protein ligase Mdm2, SULFATE ION 著者 Shimizu, H, Katakura, S, Miyazaki, M, Naito, H, Sugimoto, Y, Kawato, H, Okayama, T, Soga, T. 登録日 2013-02-12 公開日 2013-06-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Synthesis and evaluation of novel orally active p53-MDM2 interaction inhibitors Bioorg.Med.Chem., 21, 2013
3WOR	Crystal structure of the DAP BII octapeptide complex 分子名称: Angiotensin II, GLYCEROL, ZINC ION, ... 著者 Sakamoto, Y, Suzuki, Y, Iizuka, I, Tateoka, C, Roppongi, S, Fujimoto, M, Nonaka, T, Ogasawara, W, Tanaka, N. 登録日 2013-12-29 公開日 2014-09-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 S46 peptidases are the first exopeptidases to be members of clan PA SCI REP, 4, 2014
3WTW	Crystal structure of the complex comprised of ETS1(K167A), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA 分子名称: Core-binding factor subunit beta, DNA (5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ... 著者 Shiina, M, Hamada, K, Ogata, K. 登録日 2014-04-21 公開日 2014-08-20 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427, 2015
3RU2	Crystal structure of tm0922, a fusion of a domain of unknown function and ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Thermotoga maritima soaked with NADPH. 分子名称: BETA-6-HYDROXY-1,4,5,6-TETRAHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, ... 著者 Shumilin, I.A, Cymborowski, M, Lesley, S.A, Minor, W. 登録日 2011-05-04 公開日 2011-07-27 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Identification of unknown protein function using metabolite cocktail screening. Structure, 20, 2012
3WTX	Crystal structure of the complex comprised of ETS1(Y329A), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA 分子名称: Core-binding factor subunit beta, DNA (5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ... 著者 Shiina, M, Hamada, K, Ogata, K. 登録日 2014-04-21 公開日 2014-08-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427, 2015
3WOQ	Crystal structure of the DAP BII hexapeptide complex III 分子名称: Angiotensin IV, GLYCEROL, ZINC ION, ... 著者 Sakamoto, Y, Suzuki, Y, Iizuka, I, Tateoka, C, Roppongi, S, Fujimoto, M, Nonaka, T, Ogasawara, W, Tanaka, N. 登録日 2013-12-29 公開日 2014-09-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 S46 peptidases are the first exopeptidases to be members of clan PA SCI REP, 4, 2014
3WX0	The crystal structure of D-lactate dehydrogenase from Escherichia coli 分子名称: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding 著者 Furukawa, N, Togawa, M, Miyanaga, A, Nakajima, M, Taguchi, H. 登録日 2014-07-08 公開日 2015-07-08 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Allosteric D-lactate dehydrogenases from three Gram-negative bacteria To be Published
3WAF	X-ray structure of apo-TtFbpA, a ferric ion-binding protein from thermus thermophilus HB8 分子名称: ISOPROPYL ALCOHOL, Iron ABC transporter, periplasmic iron-binding protein 著者 Wang, S, Ogata, M, Horita, S, Ohtsuka, J, Nagata, K, Tanokura, M. 登録日 2013-05-02 公開日 2014-05-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A novel mode of ferric ion coordination by the periplasmic ferric ion-binding subunit FbpA of an ABC-type iron transporter from Thermus thermophilus HB8. Acta Crystallogr.,Sect.D, 70, 2014
3WTV	Crystal structure of the complex comprised of ETS1(V170G), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA 分子名称: Core-binding factor subunit beta, DNA (5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ... 著者 Shiina, M, Hamada, K, Ogata, K. 登録日 2014-04-21 公開日 2014-08-20 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427, 2015
3WFL	Crtstal structure of glycoside hydrolase family 5 beta-mannanase from Talaromyces trachyspermus 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... 著者 Suzuki, K, Ichinose, H, Kamino, K, Ogasawara, W, Kaneko, S, Fushinobu, S. 登録日 2013-07-19 公開日 2014-07-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Purification, cloning, functional expression, structure, and characterization of a thermostable beta-mannanase from Talaromyces trachyspermus and its efficiency in production of mannooligosaccharides from coffee wastes To be Published
3WHI	Crystal structure of unautoprocessed form of IS1-inserted Pro-subtilisin E 分子名称: CALCIUM ION, Subtilisin E 著者 Uehara, R, Angkawidjaja, C, Koga, Y, Kanaya, S. 登録日 2013-08-26 公開日 2013-12-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Formation of the High-Affinity Calcium Binding Site in Pro-subtilisin E with the Insertion Sequence IS1 of Pro-Tk-subtilisin Biochemistry, 52, 2013
3W5S	Crystal Structure of Maleylacetate Reductase from Rhizobium sp. strain MTP-10005 分子名称: BENZAMIDINE, GLYCEROL, Maleylacetate reductase, ... 著者 Fujii, T, Ogawa, A, Goda, Y, Yamauchi, T, Yoshida, M, Oikawa, T, Hata, Y. 登録日 2013-02-06 公開日 2014-02-12 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Crystal Structure of Maleylacetate Reductase from Rhizobium sp. strain MTP-10005 To be Published
3W7A	Crystal Structure of azoreductase AzrC fin complex with sulfone-modified azo dye Acid Red 88 分子名称: 4-[(E)-(2-hydroxynaphthalen-1-yl)diazenyl]naphthalene-1-sulfonic acid, CALCIUM ION, FLAVIN MONONUCLEOTIDE, ... 著者 Yu, J, Ogata, D, Ooi, T, Yao, M. 登録日 2013-02-27 公開日 2014-02-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structures of AzrA and of AzrC complexed with substrate or inhibitor: insight into substrate specificity and catalytic mechanism. Acta Crystallogr.,Sect.D, 70, 2014
3WON	Crystal structure of the DAP BII dipeptide complex III 分子名称: GLYCEROL, TYROSINE, VALINE, ... 著者 Sakamoto, Y, Suzuki, Y, Iizuka, I, Tateoka, C, Roppongi, S, Fujimoto, M, Nonaka, T, Ogasawara, W, Tanaka, N. 登録日 2013-12-29 公開日 2014-09-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 S46 peptidases are the first exopeptidases to be members of clan PA SCI REP, 4, 2014
3WOL	Crystal structure of the DAP BII dipeptide complex I 分子名称: GLYCEROL, TYROSINE, VALINE, ... 著者 Sakamoto, Y, Suzuki, Y, Iizuka, I, Tateoka, C, Roppongi, S, Fujimoto, M, Nonaka, T, Ogasawara, W, Tanaka, N. 登録日 2013-12-29 公開日 2014-09-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 S46 peptidases are the first exopeptidases to be members of clan PA SCI REP, 4, 2014
3W78	Crystal Structure of azoreductase AzrC in complex with NAD(P)-inhibitor Cibacron Blue 分子名称: CIBACRON BLUE, FLAVIN MONONUCLEOTIDE, FMN-dependent NADH-azoreductase 著者 Yu, J, Ogata, D, Ooi, T, Yao, M. 登録日 2013-02-27 公開日 2014-02-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Structures of AzrA and of AzrC complexed with substrate or inhibitor: insight into substrate specificity and catalytic mechanism. Acta Crystallogr.,Sect.D, 70, 2014
3WTT	Crystal structure of the complex comprised of phosphorylated ETS1, RUNX1, CBFBETA, and the tcralpha gene enhancer DNA 分子名称: 5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3', 5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3', Core-binding factor subunit beta, ... 著者 Shiina, M, Hamada, K, Ogata, K. 登録日 2014-04-21 公開日 2014-08-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427, 2015
3WOM	Crystal structure of the DAP BII dipeptide complex II 分子名称: GLYCEROL, TYROSINE, VALINE, ... 著者 Sakamoto, Y, Suzuki, Y, Iizuka, I, Tateoka, C, Roppongi, S, Fujimoto, M, Nonaka, T, Ogasawara, W, Tanaka, N. 登録日 2013-12-29 公開日 2014-09-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 S46 peptidases are the first exopeptidases to be members of clan PA SCI REP, 4, 2014
3WTS	Crystal structure of the complex comprised of ETS1, RUNX1, CBFBETA, and the tcralpha gene enhancer DNA 分子名称: 5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3', 5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3', Core-binding factor subunit beta, ... 著者 Shiina, M, Hamada, K, Ogata, K. 登録日 2014-04-21 公開日 2014-08-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427, 2015

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