PDB: 222624 件ウェブページステータス検索Chemie searchBIRD

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8VAX	Cadmium catalyzed primer extension product with 14mer primer and mixed phosphorothioate activated G monomer 分子名称: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, Cadmium catalyzed nonenzymatic RNA primer extension product, MAGNESIUM ION 著者 Fang, Z, Szostak, J.W. 登録日 2023-12-11 公開日 2024-04-17 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.417 Å) 主引用文献 Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension. J.Am.Chem.Soc., 146, 2024
8VAW	Magnesium catalyzed primer extension product with 14mer primer and mixed phosphorothioate activated G monomer 分子名称: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, Magnesium catalyzed nonenzymatic RNA primer extension product 著者 Fang, Z, Szostak, J.W. 登録日 2023-12-11 公開日 2024-04-17 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension. J.Am.Chem.Soc., 146, 2024
8VAT	Structure of the E. coli clamp loader bound to the beta clamp in a Open-RNAp/t conformation 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... 著者 Landeck, J.T, Kelch, B.A. 登録日 2023-12-11 公開日 2024-03-27 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8VAS	Structure of the E. coli clamp loader bound to the beta clamp in an Altered-Collar conformation 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... 著者 Landeck, J.T, Kelch, B.A. 登録日 2023-12-11 公開日 2024-03-27 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8VAR	Structure of the E. coli clamp loader bound to the beta clamp in a Closed-DNA2 conformation 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... 著者 Landeck, J.T, Kelch, B.A. 登録日 2023-12-11 公開日 2024-03-27 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8VAQ	Structure of the E. coli clamp loader bound to the beta clamp in a Closed-DNA1 conformation 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... 著者 Landeck, J.T, Kelch, B.A. 登録日 2023-12-11 公開日 2024-03-27 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8VAP	Structure of the E. coli clamp loader bound to the beta clamp in a Fully-Open conformation 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... 著者 Landeck, J.T, Kelch, B.A. 登録日 2023-12-11 公開日 2024-03-27 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8VAO	Simulation-driven design of prefusion stabilized SARS-CoV-2 spike S2 antigen 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2 著者 Zhou, L, McLellan, J.S. 登録日 2023-12-11 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Simulation-Driven Design of Stabilized SARS-CoV-2 Spike S2 Immunogens To Be Published
8VAN	Structure of the E. coli clamp loader bound to the beta clamp in an Initial-Binding conformation 分子名称: Beta sliding clamp, DNA polymerase III subunit delta, DNA polymerase III subunit delta', ... 著者 Landeck, J.T, Pajak, J, Kelch, B.A. 登録日 2023-12-11 公開日 2024-03-27 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (7.7 Å) 主引用文献 Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8VAM	Structure of the E. coli clamp loader bound to the beta clamp in a Semi-Open conformation 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... 著者 Landeck, J.T, Kelch, B.A. 登録日 2023-12-11 公開日 2024-03-27 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8VAL	Structure of the E. coli clamp loader bound to the beta clamp in a Open-DNAp/t conformation 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... 著者 Landeck, J.T, Kelch, B.A. 登録日 2023-12-11 公開日 2024-03-27 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8VAF	Cryogenic electron microscopy structure of apo human serum albumin 分子名称: Serum albumin 著者 Catalano, C, Lucier, K.W, To, D, Senko, S, Tran, N.L, Farwell, A.C, Silva, S.M, Dip, P.V, Poweleit, N, Scapin, G. 登録日 2023-12-11 公開日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 The CryoEM structure of human serum albumin in complex with ligands. J.Struct.Biol., 216, 2024
8VAE	Cryogenic electron microscopy structure of human serum albumin in complex with salicylic acid 分子名称: 2-HYDROXYBENZOIC ACID, Serum albumin 著者 Catalano, C, Lucier, K.W, To, D, Senko, S, Tran, N.L, Farwell, A.C, Silva, S.M, Dip, P.V, Poweleit, N, Scapin, G. 登録日 2023-12-11 公開日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 The CryoEM structure of human serum albumin in complex with ligands. J.Struct.Biol., 216, 2024
8VAC	Cryogenic electron microscopy structure of human serum albumin in complex with teniposide 分子名称: (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-(thiophen-2-ylmethylidene)-beta-D-glucopyranoside, Serum albumin 著者 Catalano, C, Lucier, K.W, To, D, Senko, S, Tran, N.L, Farwell, A.C, Silva, S.M, Dip, P.V, Poweleit, N, Scapin, G. 登録日 2023-12-11 公開日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 The CryoEM structure of human serum albumin in complex with ligands. J.Struct.Biol., 216, 2024
8VA2	Symmetry expanded map of 2 gamma-tubulins bound to 2 alpha tubulins in gamma tubulin ring complex capped microtubule end. 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Aher, A, Urnavicius, L, Kapoor, T.M. 登録日 2023-12-10 公開日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Symmetry expanded map of 2 gamma-tubulins bound to 2 alpha tubulins. To Be Published
8VA1	S. aureus TarL H300N in complex with CDP-ribitol (single tetramer) 分子名称: CDP-ribitol, Teichoic acid ribitol-phosphate polymerase TarL 著者 Li, F.K.K, Worrall, L.J, Strynadka, N.C.J. 登録日 2023-12-10 公開日 2024-04-03 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Cryo-EM analysis of S. aureus TarL, a polymerase in wall teichoic acid biogenesis central to virulence and antibiotic resistance. Sci Adv, 10, 2024
8V9U	Solution NMR structure of human DNMT1 N-terminal alpha-helical domain 分子名称: DNA (cytosine-5)-methyltransferase 1 著者 Hu, Q, Botuyan, M.V, Mer, G. 登録日 2023-12-09 公開日 2024-02-28 最終更新日 2024-06-05 実験手法 SOLUTION NMR 主引用文献 Identification of a conserved alpha-helical domain at the N terminus of human DNA methyltransferase 1. J.Biol.Chem., 300, 2024
8V9Q	Crystal structure of mGalNAc-T1 in complex with the mucin glycopeptide Muc5AC-13, Mn2+, and UDP. 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Samara, N.L, Collette, A.M. 登録日 2023-12-08 公開日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 An unusual dual sugar-binding lectin domain controls the substrate specificity of a mucin-type O-glycosyltransferase. Sci Adv, 10, 2024
8V9P	Proteus vulgaris tryptophan indole-lyase complexed with (3S)-dioxindolyl-L-alanine 分子名称: (2~{E})-2-[(~{Z})-[2-methyl-3-oxidanyl-5-[[oxidanyl-bis(oxidanylidene)-$l^{6}-phosphanyl]oxymethyl]-1~{H}-pyridin-4-ylidene]methyl]imino-3-[(3~{S})-3-oxidanyl-2-oxidanylidene-1~{H}-indol-3-yl]propanoic acid, DIMETHYL SULFOXIDE, POTASSIUM ION, ... 著者 Phillips, R.S. 登録日 2023-12-08 公開日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Proteus vulgaris tryptophan indole-lyase complexed with L-ethionine To Be Published
8V9O	Imaging scaffold engineered to bind the therapeutic protein target BARD1 分子名称: CALCIUM ION, Tetrahedral Nanocage Cage Component Fused to Anti-BARD1 Darpin, Tetrahedral Nanocage Cage, ... 著者 Agdanowski, M.P, Castells-Graells, R, Sawaya, M.R, Yeates, T.O, Arbing, M.A. 登録日 2023-12-08 公開日 2024-05-15 最終更新日 2024-06-12 実験手法 X-RAY DIFFRACTION (3.81 Å) 主引用文献 X-ray crystal structure of a designed rigidified imaging scaffold in the ligand-free conformation. Acta Crystallogr.,Sect.F, 80, 2024
8V9M	Human Ornithine Aminotransferase cocrystallized with its inhibitor, (R)-3-amino-5,5-difluorocyclohex-1-ene-1-carboxylic acid. 分子名称: 3-fluoro-5-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]benzoic acid, GLYCEROL, Ornithine aminotransferase, ... 著者 Vargas, A.L, Devitt, A, Kaley, N, Silverman, R, Liu, D. 登録日 2023-12-08 公開日 2024-05-08 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Design, Synthesis, and Mechanistic Studies of ( R )-3-Amino-5,5-difluorocyclohex-1-ene-1-carboxylic Acid as an Inactivator of Human Ornithine Aminotransferase. Acs Chem.Biol., 19, 2024
8V9L	Cryo-EM structure of the Mycobacterium smegmatis 70S ribosome in complex with hibernation factor Msmeg1130 (Balon) and MsmegEF-Tu(GDP) (Composite structure 6) 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S2, ... 著者 Rybak, M.Y, Helena-Bueno, K, Hill, C.H, Melnikov, S.V, Gagnon, M.G. 登録日 2023-12-08 公開日 2024-02-07 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
8V9K	Cryo-EM structure of the Mycobacterium smegmatis 70S ribosome in complex with hibernation factor Rv2629 (Balon) (Structure 5) 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S2, ... 著者 Rybak, M.Y, Helena-Bueno, K, Hill, C.H, Melnikov, S.V, Gagnon, M.G. 登録日 2023-12-08 公開日 2024-02-07 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
8V9J	Cryo-EM structure of the Mycobacterium smegmatis 70S ribosome in complex with hibernation factor Msmeg1130 (Balon) (Structure 4) 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S14, ... 著者 Rybak, M.Y, Helena-Bueno, K, Hill, C.H, Melnikov, S.V, Gagnon, M.G. 登録日 2023-12-08 公開日 2024-02-07 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
8V9I	1-deoxy-D-xylulose 5-phosphate synthase (DXPS) from Deinococcus radiodurans with D-phenylalanine-derived triazole acetylphosphonate (D-PheTrAP) bound 分子名称: 1-deoxy-D-xylulose-5-phosphate synthase, 2-HYDROXY BUTANE-1,4-DIOL, 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-{(1S)-1-[(S)-(2-{1-[(1R)-1-carboxy-2-phenylethyl]-1H-1,2,3-triazol-4-yl}ethoxy)(hydroxy)phosphoryl]-1-hydroxyethyl}-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium, ... 著者 Chen, P.Y.-T, Drennan, C.L. 登録日 2023-12-08 公開日 2024-04-24 実験手法 X-RAY DIFFRACTION (1.981 Å) 主引用文献 Potent Inhibition of E. coli DXP Synthase by a gem -Diaryl Bisubstrate Analog. Acs Infect Dis., 10, 2024

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