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4V4F
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The structure of the trp RNA-binding attenuation protein (TRAP) bound to a RNA molecule containing UAGAU repeats
分子名称: 5'-R(*UP*AP*GP*AP*UP)-3', TRANSCRIPTION ATTENUATION PROTEIN MTRB, TRYPTOPHAN
著者Hopcroft, N.H, Manfredo, A, Wendt, A.L, Brzozowski, A.M, Gollnick, P, Antson, A.A.
登録日2003-12-08
公開日2014-07-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Interaction of RNA with Trap: The Role of Triplet Repeats and Separating Spacer Nucleotides
J.Mol.Biol., 338, 2004
3BVP
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Crystal Structure of the N-terminal Catalytic Domain of TP901-1 Integrase
分子名称: TP901-1 Integrase
著者Yuan, P, Van Duyne, G.D.
登録日2008-01-07
公開日2008-08-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Tetrameric structure of a serine integrase catalytic domain.
Structure, 16, 2008
4W4G
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Postcleavage state of 70S bound to HigB toxin and AAA (lysine) codon
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Schureck, M.A, Maehigashi, T, Dunkle, J.A, Dunham, C.M.
登録日2014-08-14
公開日2015-10-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Defining the mRNA recognition signature of a bacterial toxin protein.
Proc.Natl.Acad.Sci.USA, 112, 2015
4V8B
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Crystal structure analysis of ribosomal decoding (near-cognate tRNA-leu complex).
分子名称: 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
著者Jenner, L, Demeshkina, N, Yusupov, M, Yusupova, G.
登録日2011-12-06
公開日2014-07-09
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A new understanding of the decoding principle on the ribosome.
Nature, 484, 2012
4V9N
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BU of 4v9n by Molmil
Crystal structure of the 70S ribosome bound with the Q253P mutant of release factor RF2.
分子名称: 16S rRNA (1504-MER), 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Santos, N, Zhu, J, Donohue, J.P, Korostelev, A.A, Noller, H.F.
登録日2013-04-26
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Crystal Structure of the 70S Ribosome Bound with the Q253P Mutant Form of Release Factor RF2.
Structure, 21, 2013
4V6A
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BU of 4v6a by Molmil
Structure of EF-P bound to the 70S ribosome.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Stanley, R.E, Blaha, G.
登録日2009-06-15
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Formation of the first peptide bond: the structure of EF-P bound to the 70S ribosome.
Science, 325, 2009
4V82
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Crystal structure of cyanobacterial Photosystem II in complex with terbutryn
分子名称: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
著者Gabdulkhakov, A, Broser, M, Guskov, A, Kern, J, Glockner, C, Muh, F, Saenger, W, Zouni, A.
登録日2010-11-30
公開日2014-07-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis of cyanobacterial photosystem II Inhibition by the herbicide terbutryn
J.Biol.Chem., 286, 2011
4V83
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Crystal structure of a complex containing domain 3 from the PSIV IGR IRES RNA bound to the 70S ribosome.
分子名称: 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Zhu, J, Korostelev, A, Costantino, D, Noller, H.F, Kieft, J.S.
登録日2010-12-13
公開日2014-07-09
最終更新日2014-12-10
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystal structures of complexes containing domains from two viral internal ribosome entry site (IRES) RNAs bound to the 70S ribosome.
Proc.Natl.Acad.Sci.USA, 108, 2011
1MP1
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BU of 1mp1 by Molmil
Solution structure of the PWI motif from SRm160
分子名称: Ser/Arg-related nuclear matrix protein
著者Szymczyna, B.R, Bowman, J, McCracken, S, Pineda-Lucena, A, Lu, Y, Cox, B, Lambermon, M, Graveley, B.R, Arrowsmith, C.H, Blencowe, B.J.
登録日2002-09-11
公開日2003-09-16
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and function of the PWI motif: a novel nucleic acid-binding domain that facilitates pre-mRNA processing.
Genes Dev., 17, 2003
1M13
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Crystal Structure of the Human Pregane X Receptor Ligand Binding Domain in Complex with Hyperforin, a Constituent of St. John's Wort
分子名称: 4-HYDROXY-5-ISOBUTYRYL-6-METHYL-1,3,7-TRIS-(3-METHYL-BUT-2-ENYL)-6-(4-METHYL-PENT-3-ENYL)-BICYCLO[3.3.1]NON-3-ENE-2,9-DIONE, Orphan Nuclear Receptor PXR
著者Watkins, R.E, Maglich, J.M, Moore, L.B, Wisely, G.B, Noble, S.M, Davis-Searles, P.R, Lambert, M.H, Kliewer, S.A, Redinbo, M.R.
登録日2002-06-17
公開日2003-03-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献2.1 A Crystal Structure of Human PXR in Complex with the St. John's Wort Compound Hyperforin
Biochemistry, 42, 2003
4W2R
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Structure of Hs/AcPRC2 in complex with 5,8-dichloro-2-[(4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-7-[(R)-methoxy(oxetan-3-yl)methyl]-3,4-dihydroisoquinolin-1(2H)-one
分子名称: 5,8-dichloro-2-[(4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-7-[(R)-methoxy(oxetan-3-yl)methyl]-3,4-dihydroisoquinolin-1(2H)-one, Enhancer of zeste 2 polycomb repressive complex 2 subunit, Polycomb protein EED, ...
著者Gajiwala, K.S, Brooun, A, Liu, W, Deng, Y, Stewart, A.E.
登録日2017-09-25
公開日2017-12-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Optimization of Orally Bioavailable Enhancer of Zeste Homolog 2 (EZH2) Inhibitors Using Ligand and Property-Based Design Strategies: Identification of Development Candidate (R)-5,8-Dichloro-7-(methoxy(oxetan-3-yl)methyl)-2-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3,4-dihydroisoquinolin-1(2H)-one (PF-06821497).
J. Med. Chem., 61, 2018
4W2F
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BU of 4w2f by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with amicoumacin, mRNA and three deacylated tRNAs in the A, P and E sites
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Polikanov, Y.S, Osterman, I.A, Szal, T, Tashlitsky, V.N, Serebryakova, M.V, Kusochek, P, Bulkley, D, Malanicheva, I.A, Efimenko, T.A, Efremenkova, O.V, Konevega, A.L, Shaw, K.J, Bogdanov, A.A, Rodnina, M.V, Dontsova, O.A, Mankin, A.S, Steitz, T.A, Sergiev, P.V.
登録日2014-09-12
公開日2014-10-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
Mol.Cell, 56, 2014
4WQF
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Crystal structure of the Thermus thermophilus 70S ribosome in complex with elongation factor G and fusidic acid in the post-translocational state
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Lin, J, Gagnon, M.G, Steitz, T.A.
登録日2014-10-21
公開日2015-01-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation.
Cell, 160, 2015
4WM7
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Crystal Structure of Human Enterovirus D68 in Complex with Pleconaril
分子名称: 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, VP1, VP2, ...
著者Liu, Y, Sheng, J, Fokine, A, Meng, G, Long, F, Kuhn, R.J, Rossmann, M.G.
登録日2014-10-08
公開日2015-01-14
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Virus structure. Structure and inhibition of EV-D68, a virus that causes respiratory illness in children.
Science, 347, 2015
4WRA
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BU of 4wra by Molmil
Complex of 70S ribosome with tRNA-Tyr and mRNA with A-A mismatch in the first position in the A-site and with antibiotic paromomycin.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
登録日2014-10-23
公開日2015-06-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4WQ1
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Complex of 70S ribosome with tRNA-Tyr and mRNA with C-A mismatch in the first position in the A-site.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
登録日2014-10-21
公開日2015-06-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4V8E
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BU of 4v8e by Molmil
Crystal structure analysis of ribosomal decoding (near-cognate tRNA-tyr complex).
分子名称: 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
著者Jenner, L, Demeshkina, N, Yusupov, M, Yusupova, G.
登録日2011-12-07
公開日2014-07-09
最終更新日2019-07-03
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A new understanding of the decoding principle on the ribosome.
Nature, 484, 2012
4V97
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BU of 4v97 by Molmil
Crystal structure of the bacterial ribosome ram mutation G299A.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Fagan, C.E, Dunkle, J.A, Maehigashi, T, Dunham, C.M.
登録日2012-04-06
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.516 Å)
主引用文献Reorganization of an intersubunit bridge induced by disparate 16S ribosomal ambiguity mutations mimics an EF-Tu-bound state.
Proc.Natl.Acad.Sci.USA, 110, 2013
4WSG
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BU of 4wsg by Molmil
Crystal Structure of Soluble WR PIV5 F-GCNt
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0
著者Poor, T.A, Song, A.S, Welch, B.D, Kors, C.A, Jardetzky, T.S, Lamb, R.A.
登録日2014-10-27
公開日2015-01-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal Structure of Soluble WR PIV5 F-GCNt
J.Virol., 89, 2015
4WPO
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BU of 4wpo by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with elongation factor G in the pre-translocational state
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Lin, J, Gagnon, M.G, Steitz, T.A.
登録日2014-10-20
公開日2015-01-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation.
Cell, 160, 2015
4WU1
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Complex of 70S ribosome with tRNA-Tyr and mRNA with G-U mismatch in the second position in the P-site
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
登録日2014-10-30
公開日2015-06-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4X51
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X-ray structure of mouse interleukin-10 mutant - S1_E8del, C149Y
分子名称: Interleukin-10
著者Kuenze, G.
登録日2014-12-04
公開日2015-01-14
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献X-ray structure of mouse interleukin-10 mutant - S1_E8del, C149Y
To Be Published
4V6F
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Elongation complex of the 70S ribosome with three tRNAs and mRNA.
分子名称: 16S ribosomal RNA, 23S RIBOSOMAL RNA, 23S RRNA, ...
著者Jenner, L.B, Yusupova, G, Yusupov, M.
登録日2009-07-09
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural aspects of messenger RNA reading frame maintenance by the ribosome.
Nat.Struct.Mol.Biol., 17, 2010
4V8R
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The crystal structures of the eukaryotic chaperonin CCT reveal its functional partitioning
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
著者Kalisman, N, Schroder, G.F, Levitt, M.
登録日2012-03-28
公開日2014-07-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献The Crystal Structures of the Eukaryotic Chaperonin Cct Reveal its Functional Partitioning
Structure, 21, 2013
4V8F
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Crystal structure analysis of ribosomal decoding (near-cognate tRNA-ttyr complex with paromomycin).
分子名称: 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
著者Jenner, L, Demeshkina, N, Yusupov, M, Yusupova, G.
登録日2011-12-07
公開日2014-07-09
最終更新日2019-07-03
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A new understanding of the decoding principle on the ribosome.
Nature, 484, 2012

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