PDB: 5653 件ウェブページステータス検索Chemie searchBIRD

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1LOQ	Crystal structure of orotidine monophosphate decarboxylase complexed with product UMP 分子名称: URIDINE-5'-MONOPHOSPHATE, orotidine 5'-monophosphate decarboxylase 著者 Wu, N, Pai, E.F. 登録日 2002-05-06 公開日 2002-08-07 最終更新日 2018-01-31 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structures of inhibitor complexes reveal an alternate binding mode in orotidine-5'-monophosphate decarboxylase. J.Biol.Chem., 277, 2002
1KLY	Orotidine monophosphate decarboxylase D70G mutant complexed with 6-azaUMP 分子名称: 6-AZA URIDINE 5'-MONOPHOSPHATE, OROTIDINE 5'-PHOSPHATE DECARBOXYLASE 著者 Wu, N, Gillon, W, Pai, E.F. 登録日 2001-12-13 公開日 2002-06-28 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Mapping the active site-ligand interactions of orotidine 5'-monophosphate decarboxylase by crystallography. Biochemistry, 41, 2002
1KM4	crystal structure of ODCase mutant K72A complexed with UMP 分子名称: OROTIDINE 5'-PHOSPHATE DECARBOXYLASE, URIDINE-5'-MONOPHOSPHATE 著者 Wu, N, Gillon, W, Pai, E.F. 登録日 2001-12-13 公開日 2002-06-28 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Mapping the active site-ligand interactions of orotidine 5'-monophosphate decarboxylase by crystallography. Biochemistry, 41, 2002
1JUB	The K136E mutant of lactococcus lactis dihydroorotate dehydrogenase A 分子名称: FLAVIN MONONUCLEOTIDE, GLYCEROL, MAGNESIUM ION, ... 著者 Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S. 登録日 2001-08-24 公開日 2003-09-09 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function J.Biol.Chem., 278, 2003
2PRH	The structures of apo- and inhibitor bound human dihydroorotate dehydrogenase reveal conformational flexibility within the inhibitor binding site 分子名称: 6-CHLORO-2-(2'-FLUOROBIPHENYL-4-YL)-3-METHYLQUINOLINE-4-CARBOXYLIC ACID, DECYLAMINE-N,N-DIMETHYL-N-OXIDE, Dihydroorotate dehydrogenase, ... 著者 Walse, B, Dufe, V.T, Al-Karadaghi, S. 登録日 2007-05-04 公開日 2008-05-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The structures of human dihydroorotate dehydrogenase with and without inhibitor reveal conformational flexibility in the inhibitor and substrate binding sites Biochemistry, 47, 2008
2P1F	Human UMP Synthase (C-terminal Domain-Orotidine 5'-Monophosphate Decarboxylase) 分子名称: GLYCEROL, SODIUM ION, SULFATE ION, ... 著者 Liu, Y, Tang, H.L, Pai, E.F. 登録日 2007-03-05 公開日 2007-04-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Human UMP Synthase (C-terminal Domain-Orotidine 5'-Monophosphate Decarboxylase) TO BE PUBLISHED
1KLZ	Crystal structure of orotidine monophosphate decarboxylase mutant D70A complexed with UMP 分子名称: CHLORIDE ION, OROTIDINE 5'-PHOSPHATE DECARBOXYLASE, URIDINE-5'-MONOPHOSPHATE 著者 Wu, N, Gillon, W, Pai, E.F. 登録日 2001-12-13 公開日 2002-06-28 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Mapping the active site-ligand interactions of orotidine 5'-monophosphate decarboxylase by crystallography. Biochemistry, 41, 2002
1KM6	Crystal structure of ODCase mutant D70AK72A complexed with OMP 分子名称: OROTIDINE 5'-PHOSPHATE DECARBOXYLASE, OROTIDINE-5'-MONOPHOSPHATE 著者 Wu, N, Gillon, W, Pai, E.F. 登録日 2001-12-13 公開日 2002-06-28 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Mapping the active site-ligand interactions of orotidine 5'-monophosphate decarboxylase by crystallography. Biochemistry, 41, 2002
2PRZ	S. cerevisiae orotate phosphoribosyltransferase complexed with OMP 分子名称: CHLORIDE ION, OROTIDINE-5'-MONOPHOSPHATE, Orotate phosphoribosyltransferase 1 著者 Gonzalez-Segura, L, Hurley, T.D, McClard, R.W. 登録日 2007-05-04 公開日 2008-01-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.895 Å) 主引用文献 Ternary complex formation and induced asymmetry in orotate phosphoribosyltransferase. Biochemistry, 46, 2007
2PRY	Apo form of S. cerevisiae orotate phosphoribosyltransferase 分子名称: MAGNESIUM ION, Orotate phosphoribosyltransferase 1 著者 Gonzalez-Segura, L, Hurley, T.D, McClard, R.W. 登録日 2007-05-04 公開日 2008-01-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Ternary complex formation and induced asymmetry in orotate phosphoribosyltransferase. Biochemistry, 46, 2007
2Q8L	Crystal structure of orotidine 5'-phosphate decarboxylase from Plasmodium falciparum 分子名称: Orotidine-monophosphate-decarboxylase, PHOSPHATE ION 著者 Liu, Y, Lau, W, Lew, J, Amani, M, Hui, R, Pai, E.F, Structural Genomics Consortium (SGC) 登録日 2007-06-11 公開日 2007-06-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of orotidine 5'-phosphate decarboxylase from Plasmodium falciparum. To be Published
2QGA	Plasmodium vivax adenylosuccinate lyase Pv003765 with AMP bound 分子名称: ADENOSINE MONOPHOSPHATE, Adenylosuccinate lyase, CALCIUM ION, ... 著者 Lunin, V.V, Wernimont, A.K, Lew, J, Kozieradzki, I, Bochkarev, A, Arrowsmith, C.H, Sundstrom, M, Weigelt, J, Edwards, A.E, Hui, R, Hills, T, Altamentova, S, Structural Genomics Consortium (SGC) 登録日 2007-06-28 公開日 2007-07-24 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Plasmodium vivax adenylosuccinate lyase Pv003765 with AMP bound To be Published
1LOR	crystal structure of orotidine 5'-monophosphate complexed with BMP 分子名称: 6-HYDROXYURIDINE-5'-PHOSPHATE, orotidine monophosphate decarboxylase 著者 Wu, N, Pai, E.F. 登録日 2002-05-06 公開日 2002-08-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structures of inhibitor complexes reveal an alternate binding mode in orotidine-5'-monophosphate decarboxylase. J.Biol.Chem., 277, 2002
1JQX	The R57A mutant of Lactococcus lactis dihydroorotate dehydrogenase A 分子名称: FLAVIN MONONUCLEOTIDE, GLYCEROL, MAGNESIUM ION, ... 著者 Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S. 登録日 2001-08-09 公開日 2003-09-09 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function J.Biol.Chem., 278, 2003
1JRC	The N67A mutant of Lactococcus lactis dihydroorotate dehydrogenase A 分子名称: FLAVIN MONONUCLEOTIDE, OROTIC ACID, dihydroorotate dehydrogenase A 著者 Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S. 登録日 2001-08-13 公開日 2003-09-09 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function J.Biol.Chem., 278, 2003
1JUE	1.8 A resolution structure of native lactococcus lactis dihydroorotate dehydrogenase A 分子名称: ACETIC ACID, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... 著者 Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S. 登録日 2001-08-24 公開日 2003-09-09 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function J.Biol.Chem., 278, 2003
2QG9	Structure of a regulatory subunit mutant D19A of ATCase from E. coli 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, ZINC ION 著者 Stec, B, Williams, M.K, Stieglitz, K.A, Kantrowitz, E.R. 登録日 2007-06-28 公開日 2008-02-19 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Comparison of two T-state structures of regulatory-chain mutants of Escherichia coli aspartate transcarbamoylase suggests that His20 and Asp19 modulate the response to heterotropic effectors. Acta Crystallogr.,Sect.D, 63, 2007
1ML4	The PALA-liganded Aspartate transcarbamoylase catalytic subunit from Pyrococcus abyssi 分子名称: Aspartate Transcarbamoylase, N-(PHOSPHONACETYL)-L-ASPARTIC ACID 著者 Van Boxstael, S, Cunin, R, Maes, D. 登録日 2002-08-30 公開日 2003-02-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Aspartate Transcarbamylase from the Hyperthermophilic Archaeon Pyrococcus abyssi: Thermostability and 1.8A Resolution Crystal Structure of the Catalytic Subunit Complexed With the Bisubstrate Analogue N-Phosphonacetyl-L-aspartate. J.Mol.Biol., 326, 2003
2QGF	Structure of regulatory chain mutant H20A of asparate transcarbamoylase from E. coli 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, ZINC ION 著者 Stec, B, Williams, M.K, Stieglitz, K.A, Kantrowitz, E.R. 登録日 2007-06-28 公開日 2008-02-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Comparison of two T-state structures of regulatory-chain mutants of Escherichia coli aspartate transcarbamoylase suggests that His20 and Asp19 modulate the response to heterotropic effectors. Acta Crystallogr.,Sect.D, 63, 2007
4MGH	Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight from Xenon Trapping and Statistical Coupling Analysis 分子名称: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Tanwar, A.S, Goyal, V.D, Choudhary, D, Panjikar, S, Anand, R. 登録日 2013-08-28 公開日 2013-12-11 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Importance of hydrophobic cavities in allosteric regulation of formylglycinamide synthetase: insight from xenon trapping and statistical coupling analysis Plos One, 8, 2013
6M4U	Crystal structure of FKBP-FRB T2098L mutant in complex with rapamycin 分子名称: CHLORIDE ION, GLYCEROL, Peptidyl-prolyl cis-trans isomerase FKBP1A, ... 著者 Kikuchi, M, Wu, D, Inoue, T, Umehara, T. 登録日 2020-03-09 公開日 2020-08-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Rational design and implementation of a chemically inducible heterotrimerization system. Nat.Methods, 17, 2020
5X6P	Crystal structure of Pseudomonas fluorescens KMO 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase 著者 Kim, H.T, Hwang, K.Y. 登録日 2017-02-22 公開日 2018-02-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Structural Basis for Inhibitor-Induced Hydrogen Peroxide Production by Kynurenine 3-Monooxygenase Cell Chem Biol, 25, 2018
7NGE	Crystal structure of L-Trp/Indoleamine 2,3-dioxygenagse 1 (hIDO1) complex with the JK-loop refined in the closed conformation 分子名称: CHLORIDE ION, GLYCEROL, Indoleamine 2,3-dioxygenase 1, ... 著者 Mirgaux, M, Wouters, J. 登録日 2021-02-09 公開日 2021-12-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Temporary Intermediates of L-Trp Along the Reaction Pathway of Human Indoleamine 2,3-Dioxygenase 1 and Identification of an Exo Site. Int J Tryptophan Res, 14, 2021
6LYM	Crystal structure of D657A mutant of formylglycinamidine synthetase 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... 著者 Sharma, N, Tanwar, A.S, Anand, R. 登録日 2020-02-14 公開日 2021-02-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 Mechanism of Coordinated Gating and Signal Transduction in Purine Biosynthetic Enzyme Formylglycinamidine Synthetase. Acs Catalysis, 12, 2022
6LYO	Crystal Structure of H296A mutant of Formylglycinamidine Synthetase 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... 著者 Sharma, N, Tanwar, A.S, Anand, R. 登録日 2020-02-15 公開日 2021-02-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Mechanism of Coordinated Gating and Signal Transduction in Purine Biosynthetic Enzyme Formylglycinamidine Synthetase. Acs Catalysis, 12, 2022

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