PDB: 223532 件ウェブページステータス検索Chemie searchBIRD

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4R53	dihydrodipicolinate synthase from C. jejuni with vacant active site and vacant allosteric site 分子名称: 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, CHLORIDE ION, ... 著者 Conly, C.J.T. 登録日 2014-08-20 公開日 2015-10-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Tyrosine 110 plays a critical role in regulating the allosteric inhibition of Campylobacter jejuni dihydrodipicolinate synthase by lysine. Biochemistry, 53, 2014
4R2U	Crystal Structure of PPARgamma in complex with SR1664 分子名称: 4'-[(2,3-dimethyl-5-{[(1S)-1-(4-nitrophenyl)ethyl]carbamoyl}-1H-indol-1-yl)methyl]biphenyl-2-carboxylic acid, Peroxisome proliferator-activated receptor gamma 著者 Marciano, D.P, Kamenecka, T, Griffin, P.R, Bruning, J.B. 登録日 2014-08-13 公開日 2015-07-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Pharmacological repression of PPAR gamma promotes osteogenesis. Nat Commun, 6, 2015
4RBT	PduA K26A S40L mutant, from Salmonella enterica serovar Typhimurium LT2 分子名称: Propanediol utilization protein PduA, SULFATE ION 著者 Chun, S, Sawaya, M.R, Yeates, T.O. 登録日 2014-09-12 公開日 2015-02-18 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Selective molecular transport through the protein shell of a bacterial microcompartment organelle. Proc.Natl.Acad.Sci.USA, 112, 2015
4RCG	Crystal Structure Analysis of MTB PEPCK without Mn+2 分子名称: DI(HYDROXYETHYL)ETHER, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Brynda, J, Dostal, J, Snasel, J, Fanfrlik, J, Pichova, I, Machova, I. 登録日 2014-09-16 公開日 2015-04-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural and Functional Studies of Phosphoenolpyruvate Carboxykinase from Mycobacterium tuberculosis. Plos One, 10, 2015
4RCJ	Crystal structure of YTHDF1 YTH domain in complex with 5mer m6A RNA 分子名称: RNA (5'-R(*GP*GP*(6MZ)P*CP*U)-3'), UNKNOWN ATOM OR ION, YTH domain-containing family protein 1 著者 Tempel, W, Xu, C, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2014-09-16 公開日 2014-11-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural Basis for the Discriminative Recognition of N6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins. J.Biol.Chem., 290, 2015
4RF3	Crystal Structure of ketoreductase from Lactobacillus kefir, mutant A94F 分子名称: GLYCEROL, MAGNESIUM ION, NADPH dependent R-specific alcohol dehydrogenase 著者 Tang, Y, Tibrewal, N, Cascio, D. 登録日 2014-09-24 公開日 2015-09-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.694 Å) 主引用文献 Origins of stereoselectivity in evolved ketoreductases. Proc.Natl.Acad.Sci.USA, 112, 2015
4QRG	Crystal structure of I86L mutant of papain 分子名称: CHLORIDE ION, Papain, SODIUM ION 著者 Dutta, S, Choudhury, D, Roy, S, Biswas, S. 登録日 2014-07-01 公開日 2015-08-05 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (2.497 Å) 主引用文献 Pro-peptide regulates the substrate specificity and zymogen activation process of papain: A structural and mechanistic insight To be Published
4QRV	Crystal structure of I86F mutant of papain 分子名称: CHLORIDE ION, Papain, SODIUM ION 著者 Dutta, S, Choudhury, D, Roy, S. 登録日 2014-07-02 公開日 2015-08-12 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (1.978 Å) 主引用文献 Pro-peptide regulates the substrate specificity and zymogen activation process of papain: A structural and mechanistic insight to be published
4QTL	Crystal structure of human carbonic anhydrase isozyme II with inhibitor 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-(benzylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide, Carbonic anhydrase 2, ... 著者 Smirnov, A, Manakova, E, Grazulis, S. 登録日 2014-07-08 公開日 2015-04-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Functionalization of Fluorinated Benzenesulfonamides and Their Inhibitory Properties toward Carbonic Anhydrases Chemmedchem, 10, 2015
4R8Z	Crystal Structure of PA4781 HD-GYP domain from Pseudomonas aeruginosa at 2.2A resolution showing a bi-metallic Ni ion center 分子名称: CHLORIDE ION, Cyclic di-GMP phosphodiesterase, NICKEL (II) ION 著者 Giardina, G, Cutruzzolaa, F, Rinaldo, S, Stelitano, V. 登録日 2014-09-03 公開日 2015-03-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis of functional diversification of the HD-GYP domain revealed by the Pseudomonas aeruginosa PA4781 protein, which displays an unselective bimetallic binding site. J.Bacteriol., 197, 2015
4RDR	Structure of the bacterial Zn-transporter ZnuD from Neisseria meningitidis (locked conformation bound to zinc and cadmium ions) 分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, 1,2-ETHANEDIOL, CADMIUM ION, ... 著者 Calmettes, C, Moraes, T.F. 登録日 2014-09-19 公開日 2015-08-19 最終更新日 2015-09-16 実験手法 X-RAY DIFFRACTION (2.472 Å) 主引用文献 The molecular mechanism of Zinc acquisition by the neisserial outer-membrane transporter ZnuD. Nat Commun, 6, 2015
4R0P	Ifqins, an amyloid forming segment from human lysozyme spanning residues 56-61 分子名称: Lysozyme C 著者 Sievers, S, Eisenberg, D.S, Sawaya, M.R. 登録日 2014-08-01 公開日 2014-12-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Structure-based design of functional amyloid materials. J.Am.Chem.Soc., 136, 2014
4R0R	Ebolavirus GP Prehairpin Intermediate Mimic 分子名称: eboIZN21 著者 Clinton, T.R, Weinstock, M.T, Jacobsen, M.T, Szabo-Fresnais, N, Pandya, M.J, Whitby, F.G, Herbert, A.S, Prugar, L.I, McKinnon, R, Hill, C.P, Welch, B.D, Dye, J.M, Eckert, D.M, Kay, M.S. 登録日 2014-08-01 公開日 2014-10-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Design and characterization of ebolavirus GP prehairpin intermediate mimics as drug targets. Protein Sci., 24, 2015
4R11	A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo 分子名称: Cadherin-related hmr-1, IODIDE ION, Protein humpback-2 著者 Choi, H.-J, Loveless, T, Lynch, A, Bang, I, Hardin, J, Weis, W.I. 登録日 2014-08-03 公開日 2015-04-29 実験手法 X-RAY DIFFRACTION (2.789 Å) 主引用文献 A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo Dev.Cell, 33, 2015
4RGB	Crystal structure of a putative carveol dehydrogenase from Mycobacterium avium bound to NAD 分子名称: Carveol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2014-09-29 公開日 2014-10-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors. Sci Rep, 7, 2017
4QRU	Crystal Structure of HLA B*0801 in complex with ELR_MYM, ELRRKMMYM 分子名称: 55 kDa immediate-early protein 1, ACETATE ION, Beta-2-microglobulin, ... 著者 Gras, S, Twist, K.-A, Rossjohn, J. 登録日 2014-07-02 公開日 2015-02-04 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Molecular imprint of exposure to naturally occurring genetic variants of human cytomegalovirus on the T cell repertoire. Sci Rep, 4, 2014
4QSJ	Crystal structure of human carbonic anhydrase isozyme XIII with 2-chloro-4-{[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio]acetyl}benzenesulfonamide 分子名称: 1,2-ETHANEDIOL, 2-chloro-4-{[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide, CITRIC ACID, ... 著者 Smirnov, A, Manakova, E, Grazulis, S. 登録日 2014-07-04 公開日 2015-01-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Intrinsic Thermodynamics and Structure Correlation of Benzenesulfonamides with a Pyrimidine Moiety Binding to Carbonic Anhydrases I, II, VII, XII, and XIII Plos One, 9, 2014
4RF5	Crystal structure of ketoreductase from Lactobacillus kefir, E145S mutant 分子名称: GLYCEROL, MAGNESIUM ION, NADPH dependent R-specific alcohol dehydrogenase 著者 Tang, Y, Tibrewal, N, Cascio, D. 登録日 2014-09-24 公開日 2015-09-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.596 Å) 主引用文献 Origins of stereoselectivity in evolved ketoreductases. Proc.Natl.Acad.Sci.USA, 112, 2015
4RFQ	Human Methyltransferase-Like 18 分子名称: Histidine protein methyltransferase 1 homolog, S-ADENOSYLMETHIONINE, UNKNOWN ATOM OR ION 著者 Tempel, W, Ravichandran, M, Li, Y, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Hong, B.S, Structural Genomics Consortium (SGC) 登録日 2014-09-26 公開日 2014-10-08 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Human Methyltransferase-Like 18 TO BE PUBLISHED
4QQ7	Crystal Structure of Putative stringent starvation protein A from Burkholderia cenocepacia with bound glutathione 分子名称: D-glucose, GLUTATHIONE, Putative stringent starvation protein A 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2014-06-26 公開日 2014-07-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of Putative stringent starvation protein A from Burkholderia cenocepacia with bound glutathione TO BE PUBLISHED
4QR3	Brd4 Bromodomain 1 complex with its novel inhibitors 分子名称: Bromodomain-containing protein 4, N-cyclopentyl-3-(2-oxo-2,3-dihydro-1,3-thiazol-4-yl)benzenesulfonamide 著者 Xiong, B, Cao, D.Y, Chen, T.T, Xu, Y.C. 登録日 2014-06-30 公開日 2015-07-01 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.374 Å) 主引用文献 Fragment-based drug discovery of 2-thiazolidinones as BRD4 inhibitors: 2. Structure-based optimization J.Med.Chem., 58, 2015
4R22	TnrA-DNA complex 分子名称: DNA (5'-D(*CP*GP*TP*GP*TP*AP*AP*GP*GP*AP*AP*TP*TP*CP*TP*GP*AP*CP*AP*CP*G)-3'), HTH-type transcriptional regulator TnrA 著者 Schumacher, M.A. 登録日 2014-08-08 公開日 2015-03-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis. Genes Dev., 29, 2015
4QRX	Crystal structure of pro-papain mutant at pH 4.0 分子名称: pro-papain 著者 Dutta, S, Choudhury, D, Roy, S, Biswas, S. 登録日 2014-07-02 公開日 2015-08-05 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (3.138 Å) 主引用文献 Pro-peptide regulates the substrate specificity and zymogen activation process of papain: A structural and mechanistic insight to be published
4QQG	Crystal structure of an N-terminal HTATIP fragment 分子名称: Histone acetyltransferase KAT5, UNKNOWN ATOM OR ION 著者 Liu, Y, Tempel, W, Wernimont, A.K, Dobrovetsky, E, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2014-06-27 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural and histone binding studies of the chromo barrel domain of TIP60. FEBS Lett., 592, 2018
4QSA	Crystal structure of human carbonic anhydrase isozyme II with 2-chloro-4-{[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio]acetyl}benzenesulfonamide 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-chloro-4-{[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide, Carbonic anhydrase 2, ... 著者 Smirnov, A, Manakova, E, Grazulis, S. 登録日 2014-07-03 公開日 2015-01-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.501 Å) 主引用文献 Intrinsic Thermodynamics and Structure Correlation of Benzenesulfonamides with a Pyrimidine Moiety Binding to Carbonic Anhydrases I, II, VII, XII, and XIII Plos One, 9, 2014

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