5AJ0
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![BU of 5aj0 by Molmil](/molmil-images/mine/5aj0) | Cryo electron microscopy of actively translating human polysomes (POST state). | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Behrmann, E, Loerke, J, Budkevich, T.V, Yamamoto, K, Schmidt, A, Penczek, P.A, Vos, M.R, Burger, J, Mielke, T, Scheerer, P, Spahn, C.M.T. | 登録日 | 2015-02-19 | 公開日 | 2015-05-20 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural Snapshots of Actively Translating Human Ribosomes Cell(Cambridge,Mass.), 161, 2015
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6Y57
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![BU of 6y57 by Molmil](/molmil-images/mine/6y57) | Structure of human ribosome in hybrid-PRE state | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A. | 登録日 | 2020-02-25 | 公開日 | 2020-04-15 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes. Cell Rep, 31, 2020
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7JT2
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3DLL
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![BU of 3dll by Molmil](/molmil-images/mine/3dll) | The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning | 分子名称: | 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Wilson, D.N, Schluenzen, F, Harms, J.M, Starosta, A.L, Connell, S.R, Fucini, P. | 登録日 | 2008-06-27 | 公開日 | 2008-09-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning Proc.Natl.Acad.Sci.Usa, 105, 2008
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1NWX
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![BU of 1nwx by Molmil](/molmil-images/mine/1nwx) | COMPLEX OF THE LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS WITH ABT-773 | 分子名称: | 23S RIBOSOMAL RNA, 5S RIBOSOMAL RNA, CETHROMYCIN, ... | 著者 | Schluenzen, F, Harms, J, Franceschi, F, Hansen, H.A.S, Bartels, H, Zarivach, R, Yonath, A. | 登録日 | 2003-02-07 | 公開日 | 2003-03-18 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural basis for the antibiotic activity of ketolides and azalides. Structure, 11, 2003
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7BL3
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![BU of 7bl3 by Molmil](/molmil-images/mine/7bl3) | pre-50S-ObgE particle state 2 | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L11, 50S ribosomal protein L13, ... | 著者 | Hilal, T, Nikolay, R, Spahn, C.M.T. | 登録日 | 2021-01-18 | 公開日 | 2021-05-12 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization. Mol.Cell, 81, 2021
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5MEI
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![BU of 5mei by Molmil](/molmil-images/mine/5mei) | Crystal structure of Agelastatin A bound to the 80S ribosome | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | McClary, B, Zinshteyn, B, Meyer, M, Jouanneau, M, Pellegrino, S, Yusupova, G, Schuller, A, Reyes, J.C.P, Lu, J, Luo, C, Dang, Y, Romo, D, Yusupov, M, Green, R, Liu, J.O. | 登録日 | 2016-11-15 | 公開日 | 2017-06-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A. Cell Chem Biol, 24, 2017
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8PW7
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![BU of 8pw7 by Molmil](/molmil-images/mine/8pw7) | A respirasome from murine liver | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Vercellino, I, Sazanov, L.A. | 登録日 | 2023-07-19 | 公開日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | SCAF1 drives the compositional diversity of mammalian respirasomes. Nat.Struct.Mol.Biol., 2024
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1RHZ
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![BU of 1rhz by Molmil](/molmil-images/mine/1rhz) | The structure of a protein conducting channel | 分子名称: | Preprotein translocase secE subunit, Preprotein translocase secY subunit, SecBeta | 著者 | van den Berg, B, Clemons Jr, W.M, Collinson, I, Modis, Y, Hartmann, E, Harrison, S.C, Rapoport, T.A. | 登録日 | 2003-11-15 | 公開日 | 2004-01-06 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | X-ray structure of a protein-conducting channel. Nature, 427, 2004
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1XBP
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![BU of 1xbp by Molmil](/molmil-images/mine/1xbp) | Inhibition of peptide bond formation by pleuromutilins: The structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with Tiamulin | 分子名称: | 23S RIBOSOMAL RNA, 50S ribosomal protein L11, 50S ribosomal protein L13, ... | 著者 | Schluenzen, F, Pyetan, E, Fucini, P, Yonath, A, Harms, J.M. | 登録日 | 2004-08-31 | 公開日 | 2005-03-01 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin. Mol.Microbiol., 54, 2004
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8IR3
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3J7O
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![BU of 3j7o by Molmil](/molmil-images/mine/3j7o) | Structure of the mammalian 60S ribosomal subunit | 分子名称: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | 著者 | Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S. | 登録日 | 2014-08-01 | 公開日 | 2014-09-03 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution. Cell(Cambridge,Mass.), 157, 2014
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5LZE
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![BU of 5lze by Molmil](/molmil-images/mine/5lze) | Structure of the 70S ribosome with Sec-tRNASec in the classical pre-translocation state (C) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Fischer, N, Neumann, P, Bock, L.V, Maracci, C, Wang, Z, Paleskava, A, Konevega, A.L, Schroeder, G.F, Grubmueller, H, Ficner, R, Rodnina, M.V, Stark, H. | 登録日 | 2016-09-29 | 公開日 | 2016-11-23 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | The pathway to GTPase activation of elongation factor SelB on the ribosome. Nature, 540, 2016
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6UCQ
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![BU of 6ucq by Molmil](/molmil-images/mine/6ucq) | Crystal structure of the Thermus thermophilus 70S ribosome recycling complex | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Zhou, D, Tanzawa, T, Gagnon, M.G, Lin, J. | 登録日 | 2019-09-17 | 公開日 | 2019-12-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural basis for ribosome recycling by RRF and tRNA. Nat.Struct.Mol.Biol., 27, 2020
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6BUW
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![BU of 6buw by Molmil](/molmil-images/mine/6buw) | Thermus thermophilus 70S complex containing 16S G299A ram mutation and empty A site. | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M. | 登録日 | 2017-12-11 | 公開日 | 2018-11-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscoding. Nucleic Acids Res., 47, 2019
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6N8O
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![BU of 6n8o by Molmil](/molmil-images/mine/6n8o) | Cryo-EM structure of Rpl10-inserted (RI) pre-60S ribosomal subunit | 分子名称: | 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | 著者 | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | 登録日 | 2018-11-29 | 公開日 | 2019-03-13 | 最終更新日 | 2020-01-08 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome. Nat Commun, 10, 2019
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6X7F
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![BU of 6x7f by Molmil](/molmil-images/mine/6x7f) | Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B2 (TTC-B2) containing an mRNA with a 24 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Ebright, R.H, Wang, C, Su, M. | 登録日 | 2020-05-29 | 公開日 | 2020-09-02 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural basis of transcription-translation coupling. Science, 369, 2020
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7OJ0
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![BU of 7oj0 by Molmil](/molmil-images/mine/7oj0) | Cryo-EM structure of 70S ribosome stalled with TnaC peptide and RF2 | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Su, T, Kudva, R, Becker, T, Berninghausen, O, Heijne, G, Cheng, J, Beckmann, R. | 登録日 | 2021-05-13 | 公開日 | 2021-09-15 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural basis of l-tryptophan-dependent inhibition of release factor 2 by the TnaC arrest peptide. Nucleic Acids Res., 49, 2021
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6N8J
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![BU of 6n8j by Molmil](/molmil-images/mine/6n8j) | Cryo-EM structure of late nuclear (LN) pre-60S ribosomal subunit | 分子名称: | 5.8S rRNA, 5S rRNA, 60S ribosomal protein L11-A, ... | 著者 | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | 登録日 | 2018-11-29 | 公開日 | 2019-03-13 | 最終更新日 | 2020-01-08 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome. Nat Commun, 10, 2019
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6C57
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![BU of 6c57 by Molmil](/molmil-images/mine/6c57) | Crystal structure of mutant human geranylgeranyl pyrophosphate synthase (Y246D) in complex with bisphosphonate inhibitor FV0109 | 分子名称: | Geranylgeranyl pyrophosphate synthase, {[(2-{3-[(4-fluorobenzene-1-carbonyl)amino]phenyl}thieno[2,3-d]pyrimidin-4-yl)amino]methylene}bis(phosphonic acid) | 著者 | Park, J, Bin, X, Vincent, F, Tsantrizos, Y.S, Berghuis, A.M. | 登録日 | 2018-01-15 | 公開日 | 2018-09-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Unraveling the Prenylation-Cancer Paradox in Multiple Myeloma with Novel Geranylgeranyl Pyrophosphate Synthase (GGPPS) Inhibitors. J. Med. Chem., 61, 2018
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7QV1
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7QV2
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8WIB
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![BU of 8wib by Molmil](/molmil-images/mine/8wib) | Cryo- EM structure of Mycobacterium smegmatis 70S ribosome, E- tRNA and RafH. | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Kumar, N, Sharma, S, Kaushal, P.S. | 登録日 | 2023-09-24 | 公開日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Nat Commun, 15, 2024
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8WI7
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![BU of 8wi7 by Molmil](/molmil-images/mine/8wi7) | Cryo- EM structure of Mycobacterium smegmatis 70S ribosome, bS1 and RafH. | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Kumar, N, Sharma, S, Kaushal, P.S. | 登録日 | 2023-09-24 | 公開日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Nat Commun, 15, 2024
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8WIC
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![BU of 8wic by Molmil](/molmil-images/mine/8wic) | Cryo- EM structure of Mycobacterium smegmatis 50S ribosomal subunit (body 1) of 70S ribosome, E- tRNA and RafH. | 分子名称: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Kumar, N, Sharma, S, Kaushal, P.S. | 登録日 | 2023-09-24 | 公開日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Nat Commun, 15, 2024
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