PDB: 238582 件ウェブページステータス検索Chemie searchBIRD

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7MR9	Crystal structure of the first bromodomain (BD1) of human BRD4 bound to NC-II-153 分子名称: 1,2-ETHANEDIOL, 2-methyl-4-[3-(2-oxopyrrolidin-1-yl)phenyl]isoquinolin-1(2H)-one, Bromodomain-containing protein 4 著者 Chan, A, Schonbrunn, E. 登録日 2021-05-07 公開日 2022-08-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.19 Å) 主引用文献 Bivalent BET Bromodomain Inhibitors Confer Increased Potency and Selectivity for BRDT via Protein Conformational Plasticity. J.Med.Chem., 65, 2022
7MRA	Crystal structure of the first bromodomain (BD1) of human BRD4 bound to NC-II-259 分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, N-[3-(2-methyl-1-oxo-1,2-dihydroisoquinolin-4-yl)phenyl]ethanesulfonamide 著者 Chan, A, Schonbrunn, E. 登録日 2021-05-07 公開日 2022-08-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.16 Å) 主引用文献 Bivalent BET Bromodomain Inhibitors Confer Increased Potency and Selectivity for BRDT via Protein Conformational Plasticity. J.Med.Chem., 65, 2022
7MRB	Crystal structure of the first bromodomain (BD1) of human BRD4 bound to NC-III-53 分子名称: Bromodomain-containing protein 4, N-[4-(4-chlorophenoxy)-3-(2-methyl-1-oxo-1,2-dihydroisoquinolin-4-yl)phenyl]ethanesulfonamide 著者 Chan, A, Schonbrunn, E. 登録日 2021-05-07 公開日 2022-08-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Bivalent BET Bromodomain Inhibitors Confer Increased Potency and Selectivity for BRDT via Protein Conformational Plasticity. J.Med.Chem., 65, 2022
7MRH	Crystal structure of the first bromodomain (BD1) of human BRDT bound to NC-II-259 分子名称: Bromodomain testis-specific protein, N-[3-(2-methyl-1-oxo-1,2-dihydroisoquinolin-4-yl)phenyl]ethanesulfonamide 著者 Chan, A, Schonbrunn, E. 登録日 2021-05-07 公開日 2022-08-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Bivalent BET Bromodomain Inhibitors Confer Increased Potency and Selectivity for BRDT via Protein Conformational Plasticity. J.Med.Chem., 65, 2022
7MRG	Crystal structure of the first bromodomain (BD1) of human BRDT bound to NC-II-153 分子名称: 1,2-ETHANEDIOL, 2-methyl-4-[3-(2-oxopyrrolidin-1-yl)phenyl]isoquinolin-1(2H)-one, Bromodomain testis-specific protein, ... 著者 Chan, A, Schonbrunn, E. 登録日 2021-05-07 公開日 2022-08-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Bivalent BET Bromodomain Inhibitors Confer Increased Potency and Selectivity for BRDT via Protein Conformational Plasticity. J.Med.Chem., 65, 2022
7MSS	Human E105Qa GTP-specific succinyl-CoA synthetase complexed with succinate, magnesium ion and CoA 分子名称: COENZYME A, GLYCEROL, MAGNESIUM ION, ... 著者 Huang, J, Fraser, M.E. 登録日 2021-05-12 公開日 2022-10-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 The structure of succinyl-CoA synthetase bound to the succinyl-phosphate intermediate clarifies the catalytic mechanism of ATP-citrate lyase Acta Crystallogr.,Sect.F, 78, 2022
7MSR	Human E105Qa GTP-specific succinyl-CoA synthetase complexed with succinyl-phosphate, magnesium ion and desulfo-coenzyme A 分子名称: 1,2-ETHANEDIOL, 4-oxo-4-(phosphonooxy)butanoic acid, DESULFO-COENZYME A, ... 著者 Huang, J, Fraser, M.E. 登録日 2021-05-12 公開日 2022-10-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 The structure of succinyl-CoA synthetase bound to the succinyl-phosphate intermediate clarifies the catalytic mechanism of ATP-citrate lyase Acta Crystallogr.,Sect.F, 78, 2022
3JAE	Structure of alpha-1 glycine receptor by single particle electron cryo-microscopy, glycine-bound state 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alphaZ1 著者 Du, J, Lu, W, Wu, S.P, Cheng, Y.F, Gouaux, E. 登録日 2015-06-08 公開日 2015-09-09 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Glycine receptor mechanism elucidated by electron cryo-microscopy. Nature, 526, 2015
7N2O	AS4.2-YEIH-HLA*B27 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, GLYCEROL, ... 著者 Yang, X, Jude, K.M, Garcia, K.C. 登録日 2021-05-29 公開日 2022-12-07 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
7N2Q	AS4.3-YEIH-HLA*B27 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, AS4.3 T cell receptor alpha chain, AS4.3 T cell receptor beta chain, ... 著者 Yang, X, Jude, K.M, Garcia, K.C. 登録日 2021-05-29 公開日 2022-12-07 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
7N2S	AS3.1-PRPF3-HLA*B27 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, GLYCEROL, ... 著者 Yang, X, Jude, K.M, Garcia, K.C. 登録日 2021-05-29 公開日 2022-12-07 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
7N2R	AS4.3-PRPF3-HLA*B27 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, AS4.3 T cell receptor alpha chain, ... 著者 Yang, X, Jude, K.M, Garcia, K.C. 登録日 2021-05-29 公開日 2022-12-07 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
7N2N	TCR-antigen complex AS4.2-PRPF3-HLA*B27 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, GLYCEROL, ... 著者 Yang, X, Jude, K.M, Garcia, K.C. 登録日 2021-05-29 公開日 2022-12-07 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
3JVN	Crystal Structure of the acetyltransferase VF_1542 from Vibrio fischeri, Northeast Structural Genomics Consortium Target VfR136 分子名称: Acetyltransferase, SULFATE ION 著者 Forouhar, F, Neely, H, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Zhao, L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) 登録日 2009-09-17 公開日 2009-09-29 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Northeast Structural Genomics Consortium Target VfR136 To be Published
7N2P	AS4.3-RNASEH2b-HLA*B27 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, AS4.3 T cell receptor alpha chain, AS4.3 T cell receptor beta chain, ... 著者 Yang, X, Jude, K.M, Garcia, K.C. 登録日 2021-05-29 公開日 2022-12-07 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
7N4O	Crystal structure of R20A human Galectin-7 mutant 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Galectin-7 著者 Pham, N.T.H, Calmettes, C, Doucet, N. 登録日 2021-06-04 公開日 2023-01-25 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal structure of R20A human Galectin-7 mutant To Be Published
7N8G	Crystal structure of R20A-R22A human Galectin-7 mutant 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ... 著者 Pham, N.T.H, Calmettes, C, Doucet, N. 登録日 2021-06-14 公開日 2023-01-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of R20A human Galectin-7 mutant To Be Published
7MXR	Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' recessed-end DNA (r-2) 分子名称: DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... 著者 Shi, Y, Beese, L.S. 登録日 2021-05-19 公開日 2023-05-10 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.101 Å) 主引用文献 Structures of reaction intermediates reveal transient Mg2+-binding events that dynamically coordinate Human Exonuclease I activities To Be Published
7MXS	Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' recessed-end DNA (cr) 分子名称: DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... 著者 Shi, Y, Beese, L.S. 登録日 2021-05-19 公開日 2023-05-10 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.798 Å) 主引用文献 Structures of reaction intermediates reveal transient Mg2+-binding events that dynamically coordinate Human Exonuclease I activities To Be Published
7MXU	Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' flap DNA (cf2) 分子名称: DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*A)-3'), DNA (5'-D(P*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... 著者 Shi, Y, Beese, L.S. 登録日 2021-05-19 公開日 2023-05-10 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.042 Å) 主引用文献 Structures of reaction intermediates reveal transient Mg2+-binding events that dynamically coordinate Human Exonuclease I activities To Be Published
7MXV	Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' recessed-end DNA (ur) 分子名称: DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... 著者 Shi, Y, Beese, L.S. 登録日 2021-05-19 公開日 2023-05-10 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.211 Å) 主引用文献 Structures of reaction intermediates reveal transient Mg2+-binding events that dynamically coordinate Human Exonuclease I activities To Be Published
7MXT	Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' recessed-end DNA (cmr) 分子名称: DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... 著者 Shi, Y, Beese, L.S. 登録日 2021-05-19 公開日 2023-05-10 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.048 Å) 主引用文献 Structures of reaction intermediates reveal transient Mg2+-binding events that dynamically coordinate Human Exonuclease I activities To Be Published
7N6C	Crystal structure of R22A human Galectin-7 mutant 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ... 著者 Pham, N.T.H, Calmettes, C, Doucet, N. 登録日 2021-06-08 公開日 2023-01-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of R20A human Galectin-7 mutant To Be Published
3JZY	Crystal structure of human Intersectin 2 C2 domain 分子名称: Intersectin 2, UNKNOWN ATOM OR ION 著者 Shen, Y, Tempel, W, Tong, Y, Li, Y, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) 登録日 2009-09-24 公開日 2009-10-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Crystal structure of human Intersectin 2 C2 domain To be Published
7N96	Crystal structure of D103A human Galectin-7 mutant 分子名称: GLYCEROL, Galectin-7 著者 Pham, N.T.H, Calmettes, C, Doucet, N. 登録日 2021-06-16 公開日 2023-01-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Crystal structure of D103A human Galectin-7 mutant To Be Published

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