7Y82
 
 | | CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA complex bound to self RNA target | | 分子名称: | MAGNESIUM ION, RAMP superfamily protein, Self RNA target, ... | | 著者 | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | | 登録日 | 2022-06-22 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | | 主引用文献 | Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase.
Nat Commun, 13, 2022
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7Y83
 | | CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA in complex with TPR-CHAT protease bound to non-self RNA target | | 分子名称: | CHAT domain protein, MAGNESIUM ION, RAMP superfamily protein, ... | | 著者 | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | | 登録日 | 2022-06-22 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | | 主引用文献 | Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase.
Nat Commun, 13, 2022
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3BZB
 | | Crystal structure of uncharacterized protein CMQ451C from the primitive red alga Cyanidioschyzon merolae | | 分子名称: | Uncharacterized protein | | 著者 | McCoy, J.G, Bitto, E, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | | 登録日 | 2008-01-17 | | 公開日 | 2008-01-29 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Crystal structure of uncharacterized protein CMQ451C from the primitive red alga Cyanidioschyzon merolae.
To be Published
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5W1V
 | | Structure of the HLA-E-VMAPRTLIL/GF4 TCR complex | | 分子名称: | Beta-2-microglobulin, GF4 T cell receptor alpha chain, GF4 T cell receptor beta chain, ... | | 著者 | Gras, S, Walpole, N, Farenc, C, Rossjohn, J. | | 登録日 | 2017-06-04 | | 公開日 | 2017-10-04 | | 最終更新日 | 2020-01-01 | | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | | 主引用文献 | A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct alpha beta T cell receptors.
J. Biol. Chem., 292, 2017
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5VMM
 | | Staphylococcus aureus IsdB bound to human hemoglobin | | 分子名称: | Hemoglobin subunit alpha, Hemoglobin subunit beta, Iron-regulated cell wall-anchored protein, ... | | 著者 | Bowden, C.F, Chan, A.C, Murphy, M.E. | | 登録日 | 2017-04-27 | | 公開日 | 2017-11-15 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Structure-function analyses reveal key features in Staphylococcus aureus IsdB-associated unfolding of the heme-binding pocket of human hemoglobin.
J. Biol. Chem., 293, 2018
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2K2I
 | | NMR Solution structure of the C-terminal domain (T94-Y172) of the human centrin 2 in complex with a repeat sequence of human Sfi1 (R641-T660) | | 分子名称: | Centrin-2, SFI1 peptide | | 著者 | Martinez-Sanz, J, Assairi, L, Blouquit, Y, Duchambon, P, Mouawad, L, Craescu, C. | | 登録日 | 2008-04-02 | | 公開日 | 2009-02-17 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure, dynamics and thermodynamics of the human centrin 2/hSfi1 complex
J.Mol.Biol., 395, 2010
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3CAZ
 | | Crystal structure of a BAR protein from Galdieria sulphuraria | | 分子名称: | BAR protein | | 著者 | McCoy, J.G, Bitto, E, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | | 登録日 | 2008-02-20 | | 公開日 | 2008-03-04 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.344 Å) | | 主引用文献 | Crystal structure of a BAR protein from Galdieria sulphuraria.
To be Published
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5VXG
 | | Crystal structure of Xanthomonas campestris OleA E117Q bound with Cerulenin | | 分子名称: | (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, 3-oxoacyl-[ACP] synthase III, ... | | 著者 | Jensen, M.R, Wilmot, C.M. | | 登録日 | 2017-05-23 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | OleA Glu117 is key to condensation of two fatty-acyl coenzyme A substrates in long-chain olefin biosynthesis.
Biochem. J., 474, 2017
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1MQ6
 | | Crystal Structure of 3-chloro-N-[4-chloro-2-[[(5-chloro-2-pyridinyl)amino]carbonyl]-6-methoxyphenyl]-4-[[(4,5-dihydro-2-oxazolyl)methylamino]methyl]-2-thiophenecarboxamide Complexed with Human Factor Xa | | 分子名称: | 3-CHLORO-N-[4-CHLORO-2-[[(5-CHLORO-2-PYRIDINYL)AMINO]CARBONYL]-6-METHOXYPHENYL]-4-[[(4,5-DIHYDRO-2-OXAZOLYL)METHYLAMINO]METHYL]-2-THIOPHENECARBOXAMIDE, CALCIUM ION, COAGULATION FACTOR X HEAVY CHAIN, ... | | 著者 | Adler, M, Whitlow, M. | | 登録日 | 2002-09-13 | | 公開日 | 2003-01-28 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structures of Two Potent Nonamidine Inhibitors Bound to Factor Xa
Biochemistry, 41, 2002
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5VXD
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1REK
 | | Crystal structure of cAMP-dependent protein kinase complexed with balanol analog 8 | | 分子名称: | 3-[(3-SEC-BUTYL-4-HYDROXYBENZOYL)AMINO]AZEPAN-4-YL 4-(2-HYDROXY-5-METHOXYBENZOYL)BENZOATE, PENTANAL, cAMP-dependent protein kinase, ... | | 著者 | Akamine, P, Madhusudan, Brunton, L.L, Ou, H.D, Canaves, J.M, Xuong, N.H, Taylor, S.S. | | 登録日 | 2003-11-06 | | 公開日 | 2004-02-24 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Balanol analogues probe specificity determinants and the conformational malleability of the cyclic 3',5'-adenosine monophosphate-dependent protein kinase catalytic subunit
Biochemistry, 43, 2004
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5VZ7
 | | Pre-catalytic ternary complex of human Polymerase Mu (G433A) mutant with incoming nonhydrolyzable UMPNPP | | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, ... | | 著者 | Moon, A.F, Pryor, J.M, Ramsden, D.A, Kunkel, T.A, Bebenek, K, Pedersen, L.C. | | 登録日 | 2017-05-27 | | 公開日 | 2017-07-05 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.551 Å) | | 主引用文献 | Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme polymerase Mu.
Nucleic Acids Res., 45, 2017
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5VZD
 | | Pre-catalytic ternary complex of human Polymerase Mu (W434A) mutant with incoming nonhydrolyzable UMPNPP | | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, ... | | 著者 | Moon, A.F, Pryor, J.M, Ramsden, D.A, Kunkel, T.A, Bebenek, K, Pedersen, L.C. | | 登録日 | 2017-05-27 | | 公開日 | 2017-07-05 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.602 Å) | | 主引用文献 | Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme polymerase Mu.
Nucleic Acids Res., 45, 2017
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4FEV
 | | Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor pyrazolopyrimidine PP1 | | 分子名称: | 1-TER-BUTYL-3-P-TOLYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE, ACETATE ION, Aminoglycoside 3'-phosphotransferase AphA1-IAB, ... | | 著者 | Stogios, P.J, Evdokimova, E, Wawrzak, Z, Minasov, G, Egorova, O, Di Leo, R, Shakya, T, Spanogiannopoulos, P, Wright, G.D, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2012-05-30 | | 公開日 | 2012-06-20 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance.
Biochem.J., 454, 2013
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1RE8
 | | Crystal structure of cAMP-dependent protein kinase complexed with balanol analog 2 | | 分子名称: | 3-[(4-HYDROXYBENZOYL)AMINO]AZEPAN-4-YL 4-(2-HYDROXYBENZOYL)BENZOATE, N-OCTANE, cAMP-dependent protein kinase, ... | | 著者 | Akamine, P, Madhusudan, Brunton, L.L, Ou, H.D, Canaves, J.M, Xuong, N.H, Taylor, S.S. | | 登録日 | 2003-11-06 | | 公開日 | 2004-02-24 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Balanol analogues probe specificity determinants and the conformational malleability of the cyclic 3',5'-adenosine monophosphate-dependent protein kinase catalytic subunit
Biochemistry, 43, 2004
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1OUF
 | | CONTRIBUTION OF HYDROPHOBIC RESIDUES TO THE STABILITY OF HUMAN LYSOZYME: X-RAY STRUCTURE OF THE V130A MUTANT | | 分子名称: | LYSOZYME, SODIUM ION | | 著者 | Takano, K, Yamagata, Y, Fujii, S, Yutani, K. | | 登録日 | 1996-08-23 | | 公開日 | 1997-02-12 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Contribution of the hydrophobic effect to the stability of human lysozyme: calorimetric studies and X-ray structural analyses of the nine valine to alanine mutants.
Biochemistry, 36, 1997
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4OQ9
 | | Satellite Tobacco Mosaic Virus Refined to 1.4 A Resolution using non-crystallographic symmetry restraints | | 分子名称: | Coat protein, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Larson, S.B, Day, J.S, McPherson, A. | | 登録日 | 2014-02-07 | | 公開日 | 2014-09-10 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Satellite tobacco mosaic virus refined to 1.4 angstrom resolution.
Acta Crystallogr.,Sect.D, 70, 2014
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4E14
 | | Crystal structure of kynurenine formamidase conjugated with phenylmethylsulfonyl fluoride | | 分子名称: | 1,2-ETHANEDIOL, SODIUM ION, kynurenine formamidase | | 著者 | Han, Q, Robinson, H, Li, J. | | 登録日 | 2012-03-05 | | 公開日 | 2012-06-27 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Biochemical identification and crystal structure of kynurenine formamidase from Drosophila melanogaster.
Biochem.J., 446, 2012
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1K3Z
 | | X-ray crystal structure of the IkBb/NF-kB p65 homodimer complex | | 分子名称: | Transcription factor p65, transcription factor inhibitor I-kappa-B-beta | | 著者 | Shiva, M, Huang, D.B, Chen, Y, Huxford, T, Ghosh, S, Ghosh, G. | | 登録日 | 2001-10-04 | | 公開日 | 2002-10-04 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | X-ray crystal structure of an IkappaBbeta x NF-kappaB p65 homodimer complex.
J.Biol.Chem., 278, 2003
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1OUG
 | | CONTRIBUTION OF HYDROPHOBIC RESIDUES TO THE STABILITY OF HUMAN LYSOZYME: X-RAY STRUCTURE OF THE V2A MUTANT | | 分子名称: | LYSOZYME, SODIUM ION | | 著者 | Takano, K, Yamagata, Y, Fujii, S, Yutani, K. | | 登録日 | 1996-08-23 | | 公開日 | 1997-02-12 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Contribution of the hydrophobic effect to the stability of human lysozyme: calorimetric studies and X-ray structural analyses of the nine valine to alanine mutants.
Biochemistry, 36, 1997
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5XM0
 | | The mouse nucleosome structure containing H2A, H2B type3-A, H3.3, and H4 | | 分子名称: | DNA (146-MER), Histone H2A type 1-B, Histone H2B type 3-A, ... | | 著者 | Taguchi, H, Horikoshi, N, Kurumizaka, H. | | 登録日 | 2017-05-12 | | 公開日 | 2018-03-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.874 Å) | | 主引用文献 | Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration.
Nat Commun, 9, 2018
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1N6Z
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4DMR
 | | REDUCED DMSO REDUCTASE FROM RHODOBACTER CAPSULATUS WITH BOUND DMSO SUBSTRATE | | 分子名称: | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, DIMETHYL SULFOXIDE, DMSO REDUCTASE, ... | | 著者 | Mcalpine, A.S, Bailey, S. | | 登録日 | 1997-04-30 | | 公開日 | 1998-03-18 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The high resolution crystal structure of DMSO reductase in complex with DMSO.
J.Mol.Biol., 275, 1998
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1R9U
 | | Refined structure of peptaibol zervamicin IIB in methanol solution from trans-hydrogen bond J couplings | | 分子名称: | ZERVAMICIN IIB | | 著者 | Shenkarev, Z.O, Balashova, T.A, Yakimenko, Z.A, Ovchinnikova, T.V, Arseniev, A.S. | | 登録日 | 2003-10-31 | | 公開日 | 2004-11-09 | | 最終更新日 | 2018-10-10 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Biosynthetic Uniform 13C,15N-Labelling of Zervamicin Iib. Complete 13C and 15N NMR Assignment.
J.Pept.Sci., 9, 2003
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5XNF
 | | Crystal structure of the branched-chain polyamine synthase (BpsA) from Thermococcus kodakarensis | | 分子名称: | FE (III) ION, GLYCEROL, N(4)-bis(aminopropyl)spermidine synthase, ... | | 著者 | Mizohata, E, Tse, K.M, Fujita, J, Inoue, T. | | 登録日 | 2017-05-22 | | 公開日 | 2018-08-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Active site geometry of a novel aminopropyltransferase for biosynthesis of hyperthermophile-specific branched-chain polyamine.
FEBS J., 284, 2017
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