PDB: 98041 件ウェブページステータス検索Chemie searchBIRD

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7KTF	DNA Polymerase Mu, 8-oxodGTP:Ct Product State Ternary Complex, 50 mM Mg2+ (180min) 分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA (5'-D(*CP*GP*GP*CP*CP*TP*AP*CP*G)-3'), ... 著者 Jamsen, J.A, Wilson, S.H. 登録日 2020-11-24 公開日 2021-12-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.489 Å) 主引用文献 Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12, 2021
7KT8	DNA Polymerase Mu, 8-oxodGTP:At Product State Ternary Complex, 50 mM Mg2+ (180min) 分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Jamsen, J.A, Wilson, S.H. 登録日 2020-11-24 公開日 2021-12-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.701 Å) 主引用文献 Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12, 2021
7KT3	DNA Polymerase Mu, 8-oxodGTP:At Pre-Catalytic Ground State Ternary Complex, 20 mM Ca2+ (120min) 分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Jamsen, J.A, Wilson, S.H. 登録日 2020-11-24 公開日 2021-12-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.879 Å) 主引用文献 Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12, 2021
7KT4	DNA Polymerase Mu, 8-oxodGTP:At Reaction State Ternary Complex, 10 mM Mn2+ (30min) 分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Jamsen, J.A, Wilson, S.H. 登録日 2020-11-24 公開日 2021-12-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.922 Å) 主引用文献 Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12, 2021
7KT7	DNA Polymerase Mu, 8-oxodGTP:At Reaction State Ternary Complex, 50 mM Mg2+ (60min) 分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Jamsen, J.A, Wilson, S.H. 登録日 2020-11-24 公開日 2021-12-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12, 2021
7KTE	DNA Polymerase Mu, 8-oxodGTP:Ct Reaction State Ternary Complex, 50 mM Mg2+ (90min) 分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Jamsen, J.A, Wilson, S.H. 登録日 2020-11-24 公開日 2021-12-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.479 Å) 主引用文献 Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12, 2021
7KTN	DNA Polymerase Mu, 8-oxodGTP:At Product State Ternary Complex, 10 mM Mg2+ (2160min) 分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Jamsen, J.A, Wilson, S.H. 登録日 2020-11-24 公開日 2021-12-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12, 2021
7KTG	DNA Polymerase Mu, 8-oxodGTP:Ct Product State Ternary Complex, 50 mM Mg2+ (960min) 分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Jamsen, J.A, Wilson, S.H. 登録日 2020-11-24 公開日 2021-12-15 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.445 Å) 主引用文献 Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12, 2021
4QCL	Crystal structure of the catalytic core of human DNA polymerase alpha in ternary complex with an RNA-primed DNA template and dCTP 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA TEMPLATE, ... 著者 Baranovskiy, A.G, Suwa, Y, Babayeva, N.D, Gu, J, Tahirov, T.H. 登録日 2014-05-12 公開日 2014-11-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Activity and fidelity of human DNA polymerase alpha depend on primer structure J.Biol.Chem., 2018
5UBF	Crystal structure of the RctB domains 2-3, RctB-155-483 分子名称: RctB replication initiator protein 著者 Orlova, N, Waldor, M.K, Jeruzalmi, D. 登録日 2016-12-20 公開日 2017-01-11 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The replication initiator of the cholera pathogen's second chromosome shows structural similarity to plasmid initiators. Nucleic Acids Res., 45, 2017
7KT0	DNA Polymerase Mu, dGTP:At Ground State Ternary Complex, 50 mM Mg2+ (60min) 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ... 著者 Jamsen, J.A, Wilson, S.H. 登録日 2020-11-24 公開日 2022-01-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12, 2021
7KT1	DNA Polymerase Mu, dGTP:At Reaction State Ternary Complex, 50 mM Mn2+ (180min) 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Jamsen, J.A, Wilson, S.H. 登録日 2020-11-24 公開日 2022-01-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.665 Å) 主引用文献 Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12, 2021
7KSU	DNA Polymerase Mu, dGTP:Ct Product State Ternary Complex, 10 mM Mn2+ (4min) 分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Jamsen, J.A, Wilson, S.H. 登録日 2020-11-24 公開日 2022-01-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12, 2021
7KT2	DNA Polymerase Mu, dGTP:At Product State Ternary Complex, 50 mM Mn2+ (225min) 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ... 著者 Jamsen, J.A, Wilson, S.H. 登録日 2020-11-24 公開日 2022-01-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.499 Å) 主引用文献 Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12, 2021
7KSZ	DNA Polymerase Mu, dGTP:At Pre-Catalytic Ground State Ternary Complex, 10 mM Ca2+ (960min) 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ... 著者 Jamsen, J.A, Wilson, S.H. 登録日 2020-11-24 公開日 2022-01-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.417 Å) 主引用文献 Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12, 2021
5TY1	Identification of a New Zinc Binding Chemotype by Fragment Screening 分子名称: (5R)-5-(2,4-dimethoxyphenyl)-1,3-oxazolidine-2,4-dione, Carbonic anhydrase 2, SODIUM ION, ... 著者 Peat, T.S. 登録日 2016-11-18 公開日 2017-10-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Identification of a New Zinc Binding Chemotype by Fragment Screening. J. Med. Chem., 60, 2017
8GQU	AK-42 inhibitor binding human ClC-2 TMD 分子名称: 2-[[2,6-bis(chloranyl)-3-phenylmethoxy-phenyl]amino]pyridine-3-carboxylic acid, Chloride channel protein 2 著者 Wang, L. 登録日 2022-08-30 公開日 2023-07-05 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42. Nat Commun, 14, 2023
7KTK	DNA Polymerase Mu (K438D), 8-oxodGTP:Ct Ground State Ternary Complex, 50 mM Mg2+ (90min) 分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... 著者 Jamsen, J.A, Wilson, S.H. 登録日 2020-11-24 公開日 2022-05-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.419 Å) 主引用文献 Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12, 2021
7KSS	DNA Polymerase Mu, dGTP:Ct Pre-Catalytic Ground State Ternary Complex, 10 mM Ca2+ (20min) 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Jamsen, J.A, Wilson, S.H. 登録日 2020-11-24 公開日 2022-05-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.503 Å) 主引用文献 Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12, 2021
7KTH	DNA Polymerase Mu, 8-oxodGTP:Ct Product State Ternary Complex, 10 mM Mg2+ (2160min) 分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Jamsen, J.A, Wilson, S.H. 登録日 2020-11-24 公開日 2022-05-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.476 Å) 主引用文献 Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12, 2021
7KTB	DNA Polymerase Mu, 8-oxodGTP:Ct Reaction State Ternary Complex, 10 mM Mn2+ (40min) 分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Jamsen, J.A, Wilson, S.H. 登録日 2020-11-24 公開日 2022-05-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.576 Å) 主引用文献 Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12, 2021
7KTC	DNA Polymerase Mu, 8-oxodGTP:Ct Product State Ternary Complex, 10 mM Mn2+ (120min) 分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Jamsen, J.A, Wilson, S.H. 登録日 2020-11-24 公開日 2022-05-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.653 Å) 主引用文献 Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12, 2021
7KTI	DNA Polymerase Mu, 8-oxodGTP:Ct Product State Ternary Complex, 20 uM Mn2+ (120min) 分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Jamsen, J.A, Wilson, S.H. 登録日 2020-11-24 公開日 2022-05-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12, 2021
4QAX	Crystal structure of post-catalytic binary complex of Phosphoglycerate mutase from Staphylococcus aureus 分子名称: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, 2-PHOSPHOGLYCERIC ACID, MANGANESE (II) ION 著者 Roychowdhury, A, Kundu, A, Bose, M, Gujar, A, Das, A.K. 登録日 2014-05-06 公開日 2015-05-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 STRUCTURAL AND FUNCCTIONAL ANALYSIS of PHOSPHOGLYCERATE MUTASE from STAPHYLOCOCCUS AUREUS To be Published
7KTD	DNA Polymerase Mu, 8-oxodGTP:Ct Product State Ternary Complex, 10 mM Mn2+ (960min) 分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Jamsen, J.A, Wilson, S.H. 登録日 2020-11-24 公開日 2022-05-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.551 Å) 主引用文献 Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Nat Commun, 12, 2021

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