4UMG
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![BU of 4umg by Molmil](/molmil-images/mine/4umg) | Crystal structure of the Lin-41 filamin domain | 分子名称: | PROTEIN LIN-41 | 著者 | Tocchini, C, Keusch, J.J, Miller, S.B, Finger, S, Gut, H, Stadler, M, Ciosk, R. | 登録日 | 2014-05-16 | 公開日 | 2014-10-01 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | The Trim-Nhl Protein Lin-41 Controls the Onset of Developmental Plasticity in Caenorhabditis Elegans. Plos Genet., 10, 2014
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4UFZ
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![BU of 4ufz by Molmil](/molmil-images/mine/4ufz) | Synthesis of Novel NAD Dependant DNA Ligase Inhibitors via Negishi Cross-Coupling: Development of SAR and Resistance Studies | 分子名称: | 1-(2,4-dimethylbenzyl)-6-oxo-1,6-dihydropyridine-3-carboxamide, 5,7-bis(azanyl)-2-tert-butyl-4-(1,3-thiazol-2-yl)pyrido[2,3-d]pyrimidine-6-carbonitrile, DNA LIGASE | 著者 | Murphy-Benenato, K.E, Boriack-Sjodin, P.A, Martinez-Botella, G, Carcanague, D, Gingipali, L, Gowravaram, M, Harang, J, Hale, M, Ioannidis, G, Jahic, H, Johnstone, M, Kutschke, A, Laganas, V.A, Loch, J, Oguto, H, Patel, S.J. | 登録日 | 2015-03-20 | 公開日 | 2015-10-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Negishi Cross-Coupling Enabled Synthesis of Novel Nad(+)-Dependent DNA Ligase Inhibitors and Sar Development. Bioorg.Med.Chem.Lett., 25, 2015
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4UMP
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![BU of 4ump by Molmil](/molmil-images/mine/4ump) | Structure of MELK in complex with inhibitors | 分子名称: | 3-(isoquinolin-7-yl)prop-2-yn-1-ol, MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE | 著者 | Johnson, C.N, Berdini, V, Beke, L, Bonnet, P, Brehmer, D, Coyle, J.E, Day, P.J, Frederickson, M, Freyne, E.J.E, Gilissen, R.A.H.J, Hamlett, C.C.F, Howard, S, Meerpoel, L, McMenamin, R, Patel, S, Rees, D.C, Sharff, A, Sommen, F, Wu, T, Linders, J.T.M. | 登録日 | 2014-05-20 | 公開日 | 2014-10-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Fragment-Based Discovery of Type I Inhibitors of Maternal Embryonic Leucine Zipper Kinase Acs Med.Chem.Lett., 6, 2015
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4UI3
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4UHT
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4UMR
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![BU of 4umr by Molmil](/molmil-images/mine/4umr) | Structure of MELK in complex with inhibitors | 分子名称: | 4-fluoro-N-(1,2,3,4-tetrahydroisoquinolin-7-yl)benzamide, MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE | 著者 | Johnson, C.N, Berdini, V, Beke, L, Bonnet, P, Brehmer, D, Coyle, J.E, Day, P.J, Frederickson, M, Freyne, E.J.E, Gilissen, R.A.H.J, Hamlett, C.C.F, Howard, S, Meerpoel, L, McMenamin, R, Patel, S, Rees, D.C, Sharff, A, Sommen, F, Wu, T, Linders, J.T.M. | 登録日 | 2014-05-20 | 公開日 | 2014-10-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Fragment-Based Discovery of Type I Inhibitors of Maternal Embryonic Leucine Zipper Kinase Acs Med.Chem.Lett., 6, 2015
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4UI5
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7O77
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![BU of 7o77 by Molmil](/molmil-images/mine/7o77) | Structure of the PL6 family alginate lyase Patl3640 from Pseudoalteromonas atlantica T6c | 分子名称: | GLYCEROL, Poly(Beta-D-mannuronate) lyase | 著者 | Ballut, L, Violot, S, Carrique, L, Aghajari, N. | 登録日 | 2021-04-13 | 公開日 | 2021-07-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.321 Å) | 主引用文献 | Exploring molecular determinants of polysaccharide lyase family 6-1 enzyme activity. Glycobiology, 31, 2021
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4UHG
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4UIZ
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![BU of 4uiz by Molmil](/molmil-images/mine/4uiz) | N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 7-(3,4-dimethoxyphenyl)-2-(4-methanesulfonylpiperazine-1-carbonyl)-5-methyl-4H,5H-thieno-3,2-c- pyridin-4-one | 分子名称: | 1,2-ETHANEDIOL, 7-(3,4-dimethoxyphenyl)-5-methyl-2-(4-methylsulfonylpiperazin-1-yl)carbonyl-thieno[3,2-c]pyridin-4-one, BROMODOMAIN-CONTAINING PROTEIN 4 | 著者 | Chung, C, Theodoulou, N.T, Bamborough, P, Humphreys, P.G. | 登録日 | 2015-04-03 | 公開日 | 2015-04-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | 主引用文献 | The Discovery of I-Brd9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition. J.Med.Chem., 59, 2016
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4UR3
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![BU of 4ur3 by Molmil](/molmil-images/mine/4ur3) | Crystal structure of the PCE reductive dehalogenase from S. multivorans P2(1) crystal form | 分子名称: | IRON/SULFUR CLUSTER, NORPSEUDO-B12, TETRACHLOROETHENE REDUCTIVE DEHALOGENASE CATALYTIC SUBUNIT | 著者 | Bommer, M, Kunze, C, Fesseler, J, Schubert, T, Diekert, G, Dobbek, H. | 登録日 | 2014-06-25 | 公開日 | 2014-10-15 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.235 Å) | 主引用文献 | Structural Basis for Organohalide Respiration. Science, 346, 2014
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4UR0
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![BU of 4ur0 by Molmil](/molmil-images/mine/4ur0) | Crystal structure of the PCE reductive dehalogenase from S. multivorans in complex with trichloroethene | 分子名称: | 1,1,2-trichloroethene, BENZAMIDINE, GLYCEROL, ... | 著者 | Bommer, M, Kunze, C, Fesseler, J, Schubert, T, Diekert, G, Dobbek, H. | 登録日 | 2014-06-25 | 公開日 | 2014-10-15 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.798 Å) | 主引用文献 | Structural Basis for Organohalide Respiration. Science, 346, 2014
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7O7A
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4UXJ
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![BU of 4uxj by Molmil](/molmil-images/mine/4uxj) | Leishmania major Thymidine Kinase in complex with dTTP | 分子名称: | MAGNESIUM ION, THYMIDINE KINASE, THYMIDINE-5'-TRIPHOSPHATE, ... | 著者 | Timm, J, Bosch-Navarrete, C, Recio, E, Nettleship, J.E, Rada, H, Gonzalez-Pacanowska, D, Wilson, K.S. | 登録日 | 2014-08-22 | 公開日 | 2015-05-27 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural and Kinetic Characterization of Thymidine Kinase from Leishmania Major. Plos Negl Trop Dis, 9, 2015
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7O78
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![BU of 7o78 by Molmil](/molmil-images/mine/7o78) | Structure of the PL6 family chondroitinase B from Pseudopedobacter saltans, Pedsa3807 | 分子名称: | Polysaccharide lyase from Pseudopedobacter saltans, Pedsa3807 | 著者 | Ballut, L, Violot, S, Carrique, L, Aghajari, N. | 登録日 | 2021-04-13 | 公開日 | 2021-07-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Exploring molecular determinants of polysaccharide lyase family 6-1 enzyme activity. Glycobiology, 31, 2021
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4UTJ
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7NUG
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4UTQ
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![BU of 4utq by Molmil](/molmil-images/mine/4utq) | A structural model of the active ribosome-bound membrane protein insertase YidC | 分子名称: | ATP SYNTHASE SUBUNIT C, MEMBRANE PROTEIN INSERTASE YIDC | 著者 | Wickles, S, Singharoy, A, Andreani, J, Seemayer, S, Bischoff, L, Berninghausen, O, Soeding, J, Schulten, K, vanderSluis, E.O, Beckmann, R. | 登録日 | 2014-07-22 | 公開日 | 2014-07-30 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (8 Å) | 主引用文献 | A Structural Model of the Active Ribosome-Bound Membrane Protein Insertase Yidc. Elife, 3, 2014
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7O79
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![BU of 7o79 by Molmil](/molmil-images/mine/7o79) | Structure of the PL6 family polysaccharide lyase Pedsa3628 from Pseudopedobacter saltans | 分子名称: | PHOSPHATE ION, Poly(Beta-D-mannuronate) lyase | 著者 | Ballut, L, Violot, S, Carrique, L, Aghajari, N. | 登録日 | 2021-04-13 | 公開日 | 2021-07-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Exploring molecular determinants of polysaccharide lyase family 6-1 enzyme activity. Glycobiology, 31, 2021
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8CWV
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7NUH
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1BDI
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![BU of 1bdi by Molmil](/molmil-images/mine/1bdi) | PURINE REPRESSOR MUTANT-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX | 分子名称: | DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), HYPOXANTHINE, PROTEIN (PURINE REPRESSOR) | 著者 | Glasfeld, A, Schumacher, M.A, Choi, K.Y, Zalkin, H, Brennan, R.G. | 登録日 | 1996-07-25 | 公開日 | 1997-04-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | A Positively Charged Residue Bound in the Minor Groove Does not Alter the Bending of a DNA Duplex J.Am.Chem.Soc., 118, 1996
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4USN
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![BU of 4usn by Molmil](/molmil-images/mine/4usn) | The structure of the immature HIV-1 capsid in intact virus particles at sub-nm resolution | 分子名称: | P24 | 著者 | Schur, F.K.M, Hagen, W.J.H, Rumlova, M, Ruml, T, Mueller, B, Kraeusslich, H.-G, Briggs, J.A.G. | 登録日 | 2014-07-11 | 公開日 | 2014-11-05 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (8.8 Å) | 主引用文献 | Structure of the Immature HIV-1 Capsid in Intact Virus Particles at 8.8 A Resolution. Nature, 517, 2015
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8CWU
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4UXT
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![BU of 4uxt by Molmil](/molmil-images/mine/4uxt) | Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN HEAVY CHAIN ISOFORM 5A, ... | 著者 | Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. | 登録日 | 2014-08-27 | 公開日 | 2014-09-24 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (7.4 Å) | 主引用文献 | Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins. Elife, 3, 2014
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