8CIK
| Altai wapiti (Cervus elaphus sibiricus) chymosin at 2.2 A resolution | 分子名称: | Chymosin, GLYCEROL | 著者 | Diusenova, S.E, Shevtsov, M.B, Borshchevskiy, V.I, Belenkaya, S.V, Kolybalov, D.S, Arkhipov, S.G, Volosnikova, E.A, Elchaninov, V.V, Shcherbakov, D.N. | 登録日 | 2023-02-09 | 公開日 | 2023-03-08 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Altai wapiti (Cervus elaphus sibiricus) chymosin at 2.2 A resolution To Be Published
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6KSY
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4DG1
| Crystal structure of HIV-1 reverse transcriptase (RT) with polymorphism mutation K172A and K173A | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, MAGNESIUM ION, ... | 著者 | Tu, X, Kirby, K.A, Marchand, B, Sarafianos, S.G. | 登録日 | 2012-01-24 | 公開日 | 2012-06-20 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | HIV-1 Reverse Transcriptase (RT) Polymorphism 172K Suppresses the Effect of Clinically Relevant Drug Resistance Mutations to Both Nucleoside and Non-nucleoside RT Inhibitors. J.Biol.Chem., 287, 2012
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1MBM
| NSP4 proteinase from Equine Arteritis Virus | 分子名称: | chymotrypsin-like serine protease | 著者 | Barrette-Ng, I.H, Ng, K.K.-S, Mark, B.L, van Aken, D, Cherney, M.M, Garen, C, Kolodenko, Y, Gorbalenya, A.E, Snijder, E.J, James, M.N.G. | 登録日 | 2002-08-03 | 公開日 | 2002-10-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of Arterivirus nsp4: the smallest chymotrypsin-like proteinase with an alpha/beta C-terminal extension and alternate conformations of the oxyanion hole J.Biol.Chem., 277, 2002
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5XSF
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1N8O
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3LYF
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9GWD
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1YPH
| High resolution structure of bovine alpha-chymotrypsin | 分子名称: | CHYMOTRYPSIN A, chain A, chain B, ... | 著者 | Razeto, A, Galunsky, B, Kasche, V, Wilson, K.S, Lamzin, V.S. | 登録日 | 2005-01-31 | 公開日 | 2006-02-14 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | 主引用文献 | High resolution structure of native bovine alpha-chymotrypsin To be Published
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8ACX
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5XSE
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2ESU
| Crystal structure of Asn to Gln mutant of Winged Bean Chymotrypsin Inhibitor protein | 分子名称: | Chymotrypsin inhibitor 3, NICKEL (II) ION, SULFATE ION | 著者 | Dattagupta, J.K, Sen, U, Dasgupta, J, Khamrui, S. | 登録日 | 2005-10-27 | 公開日 | 2006-06-13 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Spacer Asn Determines the Fate of Kunitz (STI) Inhibitors, as Revealed by Structural and Biochemical Studies on WCI Mutants. Biochemistry, 45, 2006
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2ET2
| Crystal structure of an Asn to Ala mutant of Winged Bean Chymotrypsin Inhibitor protein | 分子名称: | Chymotrypsin inhibitor 3, NICKEL (II) ION, SULFATE ION | 著者 | Dattagupta, J.K, Sen, U, Dasgupta, J, Khamrui, S. | 登録日 | 2005-10-27 | 公開日 | 2006-06-13 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Spacer Asn Determines the Fate of Kunitz (STI) Inhibitors, as Revealed by Structural and Biochemical Studies on WCI Mutants. Biochemistry, 45, 2006
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1OFG
| GLUCOSE-FRUCTOSE OXIDOREDUCTASE | 分子名称: | GLUCOSE-FRUCTOSE OXIDOREDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Kingston, R.L, Scopes, R.K, Baker, E.N. | 登録日 | 1996-10-17 | 公開日 | 1997-04-21 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The structure of glucose-fructose oxidoreductase from Zymomonas mobilis: an osmoprotective periplasmic enzyme containing non-dissociable NADP. Structure, 4, 1996
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4V9E
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3T62
| Crystal structure of recombinant Kunitz Type serine protease Inhibitor-1 from the Caribbean Sea anemone Stichodactyla helianthus in complex with bovine chymotrypsin | 分子名称: | Chymotrypsinogen A, Kunitz-type proteinase inhibitor SHPI-1, SULFATE ION | 著者 | Garcia-Fernandez, R, Dominguez, R, Oberthuer, D, Pons, T, Gonzalez-Gonzalez, Y, Chavez, M.A, Betzel, C, Redecke, L. | 登録日 | 2011-07-28 | 公開日 | 2012-08-01 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural insights into chymotrypsin inhibition by the Kunitz-type inhibitor-1 from the marine invertebrate Stichodactyla helianthus To be Published
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1YXA
| Serpina3n, a murine orthologue of human antichymotrypsin | 分子名称: | serine (or cysteine) proteinase inhibitor, clade A, member 3N | 著者 | Horvath, A.J, Irving, J.A, Law, R.H, Rossjohn, J, Bottomley, S.P, Quinsey, N.S, Pike, R.N, Coughlin, P.B, Whisstock, J.C. | 登録日 | 2005-02-20 | 公開日 | 2005-09-06 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The murine orthologue of human antichymotrypsin: a structural paradigm for clade A3 serpins. J.Biol.Chem., 280, 2005
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1WKD
| TRNA-GUANINE TRANSGLYCOSYLASE | 分子名称: | TRNA-GUANINE TRANSGLYCOSYLASE, ZINC ION | 著者 | Romier, C, Reuter, K, Suck, D, Ficner, R. | 登録日 | 1996-08-06 | 公開日 | 1997-07-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase reveal aspartate 102 as the active site nucleophile. Biochemistry, 35, 1996
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1WKF
| TRNA-GUANINE TRANSGLYCOSYLASE | 分子名称: | TRNA-GUANINE TRANSGLYCOSYLASE, ZINC ION | 著者 | Romier, C, Reuter, K, Suck, D, Ficner, R. | 登録日 | 1996-08-06 | 公開日 | 1997-07-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase reveal aspartate 102 as the active site nucleophile. Biochemistry, 35, 1996
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1WKE
| TRNA-GUANINE TRANSGLYCOSYLASE | 分子名称: | TRNA-GUANINE TRANSGLYCOSYLASE, ZINC ION | 著者 | Romier, C, Reuter, K, Suck, D, Ficner, R. | 登録日 | 1996-08-06 | 公開日 | 1997-07-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase reveal aspartate 102 as the active site nucleophile. Biochemistry, 35, 1996
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2BSM
| Novel, potent small molecule inhibitors of the molecular chaperone Hsp90 discovered through structure-based design | 分子名称: | 5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-(4-METHOXYPHENYL)-1H-PYRAZOLE-3-CARBOXAMIDE, HEAT SHOCK PROTEIN HSP90-ALPHA | 著者 | Dymock, B.W, Barril, X, Brough, P.A, Cansfield, J.E, Massey, A, McDonald, E, Hubbard, R.E, Surgenor, A, Roughley, S.D, Webb, P, Workman, P, Wright, L, Drysdale, M.J. | 登録日 | 2005-05-23 | 公開日 | 2005-06-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Novel, potent small-molecule inhibitors of the molecular chaperone Hsp90 discovered through structure-based design. J. Med. Chem., 48, 2005
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2BT0
| Novel, potent small molecule inhibitors of the molecular chaperone Hsp90 discovered through structure-based design | 分子名称: | 4-[4-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-METHYL-1H-PYRAZOL-5-YL]-6-ETHYLBENZENE-1,3-DIOL, HEAT SHOCK PROTEIN HSP90-ALPHA | 著者 | Dymock, B.W, Barril, X, Brough, P.A, Cansfield, J.E, Massey, A, McDonald, E, Hubbard, R.E, Surgenor, A, Roughley, S.D, Webb, P, Workman, P, Wright, L, Drysdale, M.J. | 登録日 | 2005-05-24 | 公開日 | 2005-06-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Novel, potent small-molecule inhibitors of the molecular chaperone Hsp90 discovered through structure-based design. J. Med. Chem., 48, 2005
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5IBL
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5IBT
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3SM0
| tRNA-Guanine Transglycosylase in complex with lin-Benzohypoxanthine Inhibitor | 分子名称: | 4-{2-[(cyclopentylmethyl)amino]ethyl}-2-(methylamino)-3,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, GLYCEROL, Queuine tRNA-ribosyltransferase, ... | 著者 | Klebe, G, Immekus, F, Heine, A. | 登録日 | 2011-06-27 | 公開日 | 2012-06-27 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | From lin-Benzoguanines to lin-Benzohypoxanthines as Ligands for Zymomonas mobilis tRNA-Guanine Transglycosylase: Replacement of Protein-Ligand Hydrogen Bonding by Importing Water Clusters. Chemistry, 18, 2012
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