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7E6E
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Crystal structure of PMP-bound form of cysteine desulfurase SufS R376A from Bacillus subtilis in D-cycloserine-inhibition
分子名称: 1,2-ETHANEDIOL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Cysteine desulfurase SufS, ...
著者Nakamura, R, Takahashi, Y, Fujishiro, T.
登録日2021-02-22
公開日2022-03-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms.
Febs J., 289, 2022
7E6F
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Crystal structure of PMP-bound form of cysteine desulfurase SufS R376A from Bacillus subtilis in L-cycloserine-inhibition
分子名称: 1,2-ETHANEDIOL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Cysteine desulfurase SufS, ...
著者Nakamura, R, Takahashi, Y, Fujishiro, T.
登録日2021-02-22
公開日2022-03-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms.
Febs J., 289, 2022
7E7G
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BU of 7e7g by Molmil
2-aminoethylphosphonate:pyruvate aminotransferase (AEPT) native
分子名称: 2-aminoethylphosphonate--pyruvate transaminase
著者Jia, H, Zhang, Q, Bartlam, M.
登録日2021-02-26
公開日2021-03-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural characterization of a 2-aminoethylphosphonate:pyruvate aminotransferase from Pseudomonas aeruginosa PAO1.
Biochem.Biophys.Res.Commun., 552, 2021
7MHV
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BU of 7mhv by Molmil
Crystal Structure of Cysteine desulfurase NifS from Legionella pneumophila Philadelphia 1 in complex with pyridoxal 5'-phosphate
分子名称: 1,2-ETHANEDIOL, Cysteine desulfurase, PHOSPHATE ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-04-15
公開日2021-05-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal Structure of Cysteine desulfurase NifS from Legionella pneumophila Philadelphia 1 in complex with pyridoxal 5'-phosphate
to be published
7MKV
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Engineered PLP-dependent decarboxylative aldolase from Aspergillus flavus, UstD2.0, bound as the internal aldimine
分子名称: Cysteine desulfurase-like protein ustD
著者Ellis, J.M, Buller, A.R, Bingman, C.A.
登録日2021-04-27
公開日2022-05-04
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Biocatalytic synthesis of non-standard amino acids by a decarboxylative aldol reaction
Nat Catal, 5, 2022
7NS7
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BU of 7ns7 by Molmil
Human L-alanine:glyoxylate aminotransferase minor allele variant: AGXT-Mi (P11L-I340M)
分子名称: L-alanine:glyoxylate aminotransferase
著者Cellini, B, Dindo, M.
登録日2021-03-05
公開日2022-03-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural dynamics shape the fitness window of alanine:glyoxylate aminotransferase.
Protein Sci., 31, 2022
7RRN
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E. coli cysteine desulfurase SufS R56A
分子名称: CHLORIDE ION, Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE
著者Dunkle, J.A, Gogar, R, Frantom, P.A.
登録日2021-08-10
公開日2023-01-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Contributions of the active site floor in cysteine desulfurase activity
To be published
7RTK
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BU of 7rtk by Molmil
Structure of the (NIAU)2 complex with N-terminal mutation of ISCU2 Y35D at 2.5 A resolution
分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ...
著者Boniecki, M.T, Cygler, M.
登録日2021-08-13
公開日2021-08-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The essential function of ISCU2 and its conserved N-terminus in Fe/S cluster biogenesis
To Be Published
7RUJ
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E. coli cysteine desulfurase SufS N99A
分子名称: CHLORIDE ION, Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE
著者Dunkle, J.A, Gogar, R, Frantom, P.A.
登録日2021-08-17
公開日2023-01-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The beta-latch structural element of the SufS cysteine desulfurase mediates active site accessibility and SufE transpersulfurase positioning.
J.Biol.Chem., 299, 2023
7RW3
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E. coli cysteine desulfurase SufS N99D
分子名称: Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE
著者Dunkle, J.A, Gogar, R, Frantom, P.A.
登録日2021-08-19
公開日2023-01-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The beta-latch structural element of the SufS cysteine desulfurase mediates active site accessibility and SufE transpersulfurase positioning.
J.Biol.Chem., 299, 2023
7T7J
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BU of 7t7j by Molmil
Crystal Structure of Phosphoserine aminotransferase from Klebsiella pneumoniae subsp. pneumoniae in complex with Pyridoxal phosphate
分子名称: PYRIDOXAL-5'-PHOSPHATE, Phosphoserine aminotransferase
著者Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-12-15
公開日2022-01-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal Structure of Phosphoserine aminotransferase from Klebsiella pneumoniae subsp. pneumoniae in complex with Pyridoxal phosphate
to be published
7TLM
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Structure of Atopobium parvulum SufS
分子名称: Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE
著者Karunakaran, G, Couture, J.F.
登録日2022-01-18
公開日2022-02-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural analysis of Atopobium parvulum SufS cysteine desulfurase linked to Crohn's disease.
Febs Lett., 596, 2022
7TLP
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Structure of Atopobium parvulum SufS K235R
分子名称: Cysteine desulfurase, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE]
著者Karunakaran, G, Couture, J.F.
登録日2022-01-18
公開日2022-02-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Structural analysis of Atopobium parvulum SufS cysteine desulfurase linked to Crohn's disease.
Febs Lett., 596, 2022
7TLQ
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Structure of Atopobium parvulum SufS C375S
分子名称: Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE
著者Karunakaran, G, Couture, J.F.
登録日2022-01-18
公開日2022-02-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural analysis of Atopobium parvulum SufS cysteine desulfurase linked to Crohn's disease.
Febs Lett., 596, 2022
7TLR
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Structure of Atopobium parvulum SufS A34Y mutant
分子名称: Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE
著者Karunakaran, G, Couture, J.F.
登録日2022-01-18
公開日2022-02-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural analysis of Atopobium parvulum SufS cysteine desulfurase linked to Crohn's disease.
Febs Lett., 596, 2022
7XEJ
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SufS with D-cysteine for 5 min
分子名称: (2~{S})-2-[(~{E})-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3-sulfanyl-propanoic acid, 1,2-ETHANEDIOL, Cysteine desulfurase SufS, ...
著者Nakamiura, R, Fujishiro, T.
登録日2022-03-31
公開日2023-04-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献X-ray crystallographic snapshots of the thioazolidine formation upon the PLP during inhibition of SufS by D-cysteine
to be published
7XEK
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SufS with D-cysteine for 30 min
分子名称: (2~{S},4~{S})-2-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]-1,3-thiazolidine-4-carboxylic acid, 1,2-ETHANEDIOL, Cysteine desulfurase SufS, ...
著者Nakamura, R, Fujishiro, T.
登録日2022-03-31
公開日2023-04-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献X-ray crystallographic snapshots of the thioazolidine formation upon the PLP during inhibition of SufS by D-cysteine
to be published
7XEL
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BU of 7xel by Molmil
SufS soaked with D-penicillamine
分子名称: 1,2-ETHANEDIOL, Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER, ...
著者Nakamura, R, Fujishiro, T.
登録日2022-03-31
公開日2023-04-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-ray crystallographic snapshots of the thioazolidine formation upon the PLP during inhibition of SufS by D-cysteine
to be published
7XEN
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BU of 7xen by Molmil
SufS with L-penicillamine
分子名称: (2~{R})-3-methyl-2-[(~{E})-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3-sulfanyl-butanoic acid, Cysteine desulfurase SufS
著者Nakamura, R, Fujishiro, T.
登録日2022-03-31
公開日2023-04-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献X-ray crystallographic snapshots of the thioazolidine formation upon the PLP during inhibition of SufS by D-cysteine
to be published
7XEP
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BU of 7xep by Molmil
SufS with L-propargylglycine
分子名称: 1,2-ETHANEDIOL, Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER, ...
著者Nakamura, R, Fujishiro, T.
登録日2022-03-31
公開日2023-04-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Inhibition mechanism of SufS by L-propargylglycine
to be published
7XEQ
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BU of 7xeq by Molmil
NifS with D-cysteine
分子名称: (2~{S},4~{S})-2-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]-1,3-thiazolidine-4-carboxylic acid, CHLORIDE ION, Cysteine desulfurase IscS, ...
著者Nakamura, R, Fujishiro, T.
登録日2022-03-31
公開日2023-04-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献X-ray crystallographic snapshots of the thioazolidine formation upon the PLP during inhibition of SufS by D-cysteine
to be published
7XES
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NifS with L-penicillamine
分子名称: (2~{R})-3-methyl-2-[(~{E})-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3-sulfanyl-butanoic acid, CHLORIDE ION, Cysteine desulfurase IscS, ...
著者Nakamura, R, Fujishiro, T.
登録日2022-03-31
公開日2023-04-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献X-ray crystallographic snapshots of the thioazolidine formation upon the PLP during inhibition of SufS by D-cysteine
to be published
7XET
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SufS with beta-cyano-L-alanine
分子名称: (2~{E})-3-cyano-2-[[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylimino]propanoic acid, Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER, ...
著者Nakamura, R, Fujishiro, T.
登録日2022-03-31
公開日2023-04-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Inhibition mechanism of SufS by L-propargylglycine
to be published
7YB3
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SufS with D-cysteine for 1 min
分子名称: Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER, TRIETHYLENE GLYCOL
著者Nakamura, R, Fujishiro, T.
登録日2022-06-28
公開日2023-07-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Snapshots of thiazolidine fomration of PLP-dependent enzyme SufS
to be published
8A5V
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BU of 8a5v by Molmil
Crystal structure of the human phosposerine aminotransferase (PSAT)
分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Phosphoserine aminotransferase, SULFATE ION
著者Costanzi, E, Demitri, N, Ullah, R, Marchesan, F, Peracchi, A, Zangelmi, E, Storici, P, Campanini, B.
登録日2022-06-16
公開日2023-03-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献L-serine biosynthesis in the human central nervous system: Structure and function of phosphoserine aminotransferase.
Protein Sci., 32, 2023

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件を2024-10-30に公開中

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