PDB: 224004 件ウェブページステータス検索Chemie searchBIRD

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7NLA	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-119 分子名称: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-02-22 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
4U9G	Crystal structure of an H-NOX protein from S. oneidensis in the Fe(II)CO ligation state, Q154A/Q155A/K156A mutant 分子名称: CARBON MONOXIDE, NO-binding heme-dependent sensor protein, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Herzik Jr, M.A, Jonnalagadda, R, Kuriyan, J, Marletta, M.A. 登録日 2014-08-06 公開日 2014-10-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural insights into the role of iron-histidine bond cleavage in nitric oxide-induced activation of H-NOX gas sensor proteins. Proc.Natl.Acad.Sci.USA, 111, 2014
7NLE	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-118 分子名称: 14-3-3 protein sigma, 4-(4-methylpiperazin-1-yl)sulfonylbenzaldehyde, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-02-22 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7MYS	Crystal structure of a tRNA (guanine-N1)-methyltransferase from Acinetobacter baumannii AB5075-UW bound to S-adenosyl homocysteine 分子名称: S-ADENOSYL-L-HOMOCYSTEINE, tRNA (guanine-N(1)-)-methyltransferase 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-05-21 公開日 2021-06-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of a tRNA (guanine-N1)-methyltransferase from Acinetobacter baumannii AB5075-UW bound to S-adenosyl homocysteine To Be Published
7P5O	Crystal structure of Aspergillus fumigatus phosphoglucomutase in complex with the reaction intermediate 分子名称: 1,6-di-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, Phosphoglucomutase 著者 Raimi, O.G, Yan, K, van Aalten, D.M.F. 登録日 2021-07-14 公開日 2022-07-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Targeting an essential step in the biosynthetic pathway of uridine diphosphate glucose in Aspergillus fumigatus To Be Published
7NJ9	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-133 分子名称: 14-3-3 protein sigma, 4-(3,4-dihydro-2~{H}-quinolin-1-ylsulfonyl)benzaldehyde, DI(HYDROXYETHYL)ETHER, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-02-16 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7NM9	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-110 分子名称: 14-3-3 protein sigma, 6-(2-bromanylimidazol-1-yl)pyridine-3-carbaldehyde, DI(HYDROXYETHYL)ETHER, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-02-23 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7NJB	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-132 分子名称: 14-3-3 protein sigma, 4-piperidin-1-ylsulfonylbenzaldehyde, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-02-16 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
4TUV	X-ray crystal structure of CYP119 from Sulfolobus acidocaldarius, complexed with 4-(4-chlorophenyl)imidazole 分子名称: 4-(4-CHLOROPHENYL)IMIDAZOLE, Cytochrome P450 119, PROTOPORPHYRIN IX CONTAINING FE 著者 Madrona, Y. 登録日 2014-06-24 公開日 2015-02-18 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.501 Å) 主引用文献 NMR and X-ray Analysis of CYP119 Ligand Dependent Conformational Changes. To Be Published
7NK3	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-128 分子名称: 14-3-3 protein sigma, 2-(4-methylphenyl)sulfonyl-3,4-dihydro-1~{H}-isoquinoline, CALCIUM ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-02-17 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7NIF	14-3-3 sigma with Pin1 binding site pS72 and covalently bound TCF521-011 分子名称: 1-(4-methylphenyl)imidazole, 14-3-3 protein sigma, CALCIUM ION, ... 著者 Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. 登録日 2021-02-12 公開日 2021-06-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
4TZB	Structure of NDM-Metallo-beta-lactamase 分子名称: CADMIUM ION, COBALT (II) ION, Metallo-beta-lactamase, ... 著者 Ferguson, J.A, Makena, A, Brem, J, McDonough, M.A, Schofield, C.J. 登録日 2014-07-09 公開日 2015-07-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.029 Å) 主引用文献 Structure of Metallo-beta-lactamase To Be Published
7NJ8	14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1007 分子名称: 14-3-3 protein sigma, CALCIUM ION, MAGNESIUM ION, ... 著者 Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. 登録日 2021-02-16 公開日 2021-06-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
4TVO	Structure of Malate Dehydrogenase from Mycobacterium tuberculosis 分子名称: Malate dehydrogenase, SODIUM ION, SULFATE ION 著者 Ferraris, D.M, Rizzi, M. 登録日 2014-06-27 公開日 2015-01-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structures of citrate synthase and malate dehydrogenase of Mycobacterium tuberculosis. Proteins, 83, 2015
7SBU	Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with a highly potent antibody J08 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, J08 Fab heavy chain, ... 著者 Liu, H, Wilson, I.A. 登録日 2021-09-25 公開日 2022-05-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody. Proc.Natl.Acad.Sci.USA, 119, 2022
7NJ6	14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1005 分子名称: 14-3-3 protein sigma, 4-[4-(trifluoromethyl)imidazol-1-yl]benzaldehyde, CALCIUM ION, ... 著者 Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. 登録日 2021-02-16 公開日 2021-06-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
4TZ7	Crystal structure of type I phosphatidylinositol 4-phosphate 5-kinase alpha from Zebrafish 分子名称: Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 著者 Hu, J, Qin, Y, Wang, J, Li, L, Wu, D, Ha, Y. 登録日 2014-07-09 公開日 2015-09-02 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.31 Å) 主引用文献 Resolution of structure of PIP5K1A reveals molecular mechanism for its regulation by dimerization and dishevelled. Nat Commun, 6, 2015
7NIX	14-3-3 sigma with AS160 binding site pT642 分子名称: 14-3-3 protein sigma, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, MAGNESIUM ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-02-14 公開日 2021-06-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
4TZJ	Structure of C. elegans HIM-3 bound to HTP-3 closure motif-4 分子名称: C. elegans HIM-3 and HTP-3 著者 Rosenberg, S.C, Corbett, K.D. 登録日 2014-07-10 公開日 2014-11-19 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.851 Å) 主引用文献 The Chromosome Axis Controls Meiotic Events through a Hierarchical Assembly of HORMA Domain Proteins. Dev.Cell, 31, 2014
7N63	X-ray structure of HCAN_0200, an aminotransferase from Helicobacter canadensis in complex with its external aldimine 分子名称: (2R,3R,4S,5S,6R)-3,5-dihydroxy-4-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}-6-methyltetrahydro-2H-pyran-2-yl [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl dihydrogen diphosphate, 1,2-ETHANEDIOL, CHLORIDE ION, ... 著者 Griffiths, W.A, Heisdorf, C.J, Thoden, J.B, Holden, H.M. 登録日 2021-06-07 公開日 2021-06-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Investigation of the enzymes required for the biosynthesis of an unusual formylated sugar in the emerging human pathogen Helicobacter canadensis. Protein Sci., 30, 2021
7NIG	14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1008 分子名称: 14-3-3 protein sigma, 2-bromanyl-4-imidazol-1-yl-benzaldehyde, CALCIUM ION, ... 著者 Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. 登録日 2021-02-12 公開日 2021-06-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
4U18	Crystal structure of human peroxisomal delta3,delta2, enoyl-CoA isomerase (ISO-ECI2) 分子名称: CHLORIDE ION, Enoyl-CoA delta isomerase 2, mitochondrial, ... 著者 Onwukwe, G.U, Koski, M.K, Wierenga, R.K. 登録日 2014-07-15 公開日 2014-12-24 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Human Delta (3) , Delta (2) -enoyl-CoA isomerase, type 2: a structural enzymology study on the catalytic role of its ACBP domain and helix-10. Febs J., 282, 2015
7N7B	crystal structure of the N-formyltrasferase HCAN_0200 from Helicobacter canadensis on complex with folinic acid and dTDP-3-aminofucose 分子名称: (3R,4S,5R,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl][hydroxy-[[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate, 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... 著者 Heisdorf, C.J, Thoden, J.B, Holden, H.M. 登録日 2021-06-10 公開日 2021-06-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Investigation of the enzymes required for the biosynthesis of an unusual formylated sugar in the emerging human pathogen Helicobacter canadensis. Protein Sci., 30, 2021
4U1C	Crystal structure of the eIF3a/eIF3c PCI-domain heterodimer 分子名称: Eukaryotic translation initiation factor 3 subunit A, Eukaryotic translation initiation factor 3 subunit C 著者 Erzberger, J.P, Schaefer, T, Ban, N. 登録日 2014-07-15 公開日 2014-09-10 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Molecular Architecture of the 40SeIF1eIF3 Translation Initiation Complex. Cell, 158, 2014
7NJA	14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1006 分子名称: 14-3-3 protein sigma, CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... 著者 Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. 登録日 2021-02-16 公開日 2021-06-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021

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