4J1P
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![BU of 4j1p by Molmil](/molmil-images/mine/4j1p) | X-ray crystal structure of bromodomain 2 of human brd2 in complex with rvx208 to 1.08 A resolution | 分子名称: | 1,2-ETHANEDIOL, 2-[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]-5,7-dimethoxyquinazolin-4(3H)-one, Bromodomain containing 2, ... | 著者 | Stein, A.J, White, A, Suto, R.K. | 登録日 | 2013-02-01 | 公開日 | 2014-01-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | 主引用文献 | RVX-208, an Inducer of ApoA-I in Humans, Is a BET Bromodomain Antagonist. Plos One, 8, 2013
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1RUV
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![BU of 1ruv by Molmil](/molmil-images/mine/1ruv) | RIBONUCLEASE A-URIDINE VANADATE COMPLEX: HIGH RESOLUTION RESOLUTION X-RAY STRUCTURE (1.3 A) | 分子名称: | RIBONUCLEASE A, TERTIARY-BUTYL ALCOHOL, URIDINE-2',3'-VANADATE | 著者 | Ladner, J.E, Wladkowski, B, Svensson, L.A, Sjolin, L, Gilliland, G.L. | 登録日 | 1995-07-27 | 公開日 | 1997-04-01 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | X-ray structure of a ribonuclease A-uridine vanadate complex at 1.3 A resolution. Acta Crystallogr.,Sect.D, 53, 1997
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3KWY
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5O3D
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![BU of 5o3d by Molmil](/molmil-images/mine/5o3d) | Human Brd2(BD2) mutant in complex with 9-ET | 分子名称: | (2~{S})-1-[(2~{S})-2-oxidanylpropoxy]propan-2-ol, Bromodomain-containing protein 2, CHLORIDE ION, ... | 著者 | Chan, K.-H, Runcie, A.C, Ciulli, A. | 登録日 | 2017-05-23 | 公開日 | 2018-02-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Optimization of a "bump-and-hole" approach to allele-selective BET bromodomain inhibition. Chem Sci, 9, 2018
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1SCR
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![BU of 1scr by Molmil](/molmil-images/mine/1scr) | HIGH-RESOLUTION STRUCTURES OF SINGLE-METAL-SUBSTITUTED CONCANAVALIN A: THE CO,CA-PROTEIN AT 1.6 ANGSTROMS AND THE NI,CA-PROTEIN AT 2.0 ANGSTROMS | 分子名称: | CALCIUM ION, CONCANAVALIN A, NICKEL (II) ION | 著者 | Emmerich, C, Helliwell, J.R, Redshaw, M, Naismith, J.H, Harrop, S.J, Raftery, J, Kalb, A.J, Yariv, J, Dauter, Z, Wilson, K.S. | 登録日 | 1993-12-06 | 公開日 | 1994-05-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | High-resolution structures of single-metal-substituted concanavalin A: the Co,Ca-protein at 1.6 A and the Ni,Ca-protein at 2.0 A. Acta Crystallogr.,Sect.D, 50, 1994
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4CTG
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![BU of 4ctg by Molmil](/molmil-images/mine/4ctg) | The limits of structural plasticity in a picornavirus capsid revealed by a massively expanded equine rhinitis A virus particle | 分子名称: | P1 | 著者 | Bakker, S.E, Groppelli, E, Pearson, A.R, Stockley, P.G, Rowlands, D.J, Ranson, N.A. | 登録日 | 2014-03-13 | 公開日 | 2014-05-21 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (17 Å) | 主引用文献 | Limits of Structural Plasticity in a Picornavirus Capsid Revealed by a Massively Expanded Equine Rhinitis a Virus Particle. J.Virol., 88, 2014
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1JNO
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![BU of 1jno by Molmil](/molmil-images/mine/1jno) | Gramicidin A in Sodium Dodecyl Sulfate Micelles (NMR) | 分子名称: | GRAMICIDIN A | 著者 | Tucker, W.A, Sham, S, Townsley, L.E, Hinton, J.F. | 登録日 | 2001-07-24 | 公開日 | 2001-08-08 | 最終更新日 | 2023-11-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structures of Gramicidins A, B, and C Incorporated Into Sodium Dodecyl Sulfate Micelles. Biochemistry, 40, 2001
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4J8N
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5O3E
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![BU of 5o3e by Molmil](/molmil-images/mine/5o3e) | Human Brd2(BD2) mutant in complex with Me-Am1 | 分子名称: | (2~{R})-2-[(4~{S})-6-(4-chlorophenyl)-8-methoxy-1-methyl-4~{H}-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]-~{N}-ethyl-propanamide, (2~{S})-1-[(2~{S})-2-oxidanylpropoxy]propan-2-ol, Bromodomain-containing protein 2, ... | 著者 | Chan, K.-H, Runcie, A.C, Ciulli, A. | 登録日 | 2017-05-23 | 公開日 | 2018-02-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Optimization of a "bump-and-hole" approach to allele-selective BET bromodomain inhibition. Chem Sci, 9, 2018
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4NA3
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1Z9K
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4EQW
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![BU of 4eqw by Molmil](/molmil-images/mine/4eqw) | Crystal Structure of the Y361F, Y419F Mutant of Staphylococcus aureus CoADR | 分子名称: | CHLORIDE ION, COENZYME A, Coenzyme A disulfide reductase, ... | 著者 | Edwards, J.S, Wallace, B.D, Wallen, J.R, Claiborne, A, Redinbo, M.R. | 登録日 | 2012-04-19 | 公開日 | 2012-10-17 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Turnover-Dependent Covalent Inactivation of Staphylococcus aureus Coenzyme A-Disulfide Reductase by Coenzyme A-Mimetics: Mechanistic and Structural Insights. Biochemistry, 51, 2012
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1XKM
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![BU of 1xkm by Molmil](/molmil-images/mine/1xkm) | NMR structure of antimicrobial peptide distinctin in water | 分子名称: | Distinctin chain A, Distinctin chain B | 著者 | Amodeo, P, Raimondo, D, Andreotti, G, Motta, A, Scaloni, A. | 登録日 | 2004-09-29 | 公開日 | 2005-04-05 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | A folding-dependent mechanism of antimicrobial peptide resistance to degradation unveiled by solution structure of distinctin. Proc.Natl.Acad.Sci.Usa, 102, 2005
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4EQS
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![BU of 4eqs by Molmil](/molmil-images/mine/4eqs) | Crystal structure of the Y419F mutant of Staphylococcus aureus CoADR | 分子名称: | CHLORIDE ION, COENZYME A, Coenzyme A disulfide reductase, ... | 著者 | Wallace, B.D, Edwards, J.S, Wallen, J.R, Claiborne, A, Redinbo, M.R. | 登録日 | 2012-04-19 | 公開日 | 2012-10-17 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Turnover-Dependent Covalent Inactivation of Staphylococcus aureus Coenzyme A-Disulfide Reductase by Coenzyme A-Mimetics: Mechanistic and Structural Insights. Biochemistry, 51, 2012
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4EUB
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4EU5
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![BU of 4eu5 by Molmil](/molmil-images/mine/4eu5) | Succinyl-CoA:acetate CoA-transferase (AarCH6) in complex with CoA | 分子名称: | CHLORIDE ION, COENZYME A, Succinyl-CoA:acetate coenzyme A transferase | 著者 | Mullins, E.A, Kappock, T.J. | 登録日 | 2012-04-25 | 公開日 | 2012-10-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.743 Å) | 主引用文献 | Crystal Structures of Acetobacter aceti Succinyl-Coenzyme A (CoA):Acetate CoA-Transferase Reveal Specificity Determinants and Illustrate the Mechanism Used by Class I CoA-Transferases. Biochemistry, 51, 2012
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7YJB
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![BU of 7yjb by Molmil](/molmil-images/mine/7yjb) | Crystal structure of Stenoloma chusanum chalcone synthase 1 (ScCHS1) complex with CoA and Eriodictyol | 分子名称: | (2S)-2-(3,4-DIHYDROXYPHENYL)-5,7-DIHYDROXY-2,3-DIHYDRO-4H-CHROMEN-4-ONE, COENZYME A, chalcone synthase 1 (ScCHS1) | 著者 | Li, J.X, Cheng, A.X, Zhang, P. | 登録日 | 2022-07-19 | 公開日 | 2022-08-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Molecular and structural characterization of a promiscuous chalcone synthase from the fern species Stenoloma chusanum. J Integr Plant Biol, 64, 2022
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7YJ9
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3MJG
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![BU of 3mjg by Molmil](/molmil-images/mine/3mjg) | The structure of a platelet derived growth factor receptor complex | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-type platelet-derived growth factor receptor, ... | 著者 | Shim, A.H.R, He, X. | 登録日 | 2010-04-12 | 公開日 | 2010-06-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structures of a platelet-derived growth factor/propeptide complex and a platelet-derived growth factor/receptor complex. Proc.Natl.Acad.Sci.USA, 107, 2010
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4DTG
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![BU of 4dtg by Molmil](/molmil-images/mine/4dtg) | Hemostatic effect of a monoclonal antibody mAb 2021 blocking the interaction between FXa and TFPI in a rabbit hemophilia model | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Humanized recombinant FAB fragment, ... | 著者 | Svensson, L.A, Breinholt, J, Krogh, B.O, Hilden, I. | 登録日 | 2012-02-21 | 公開日 | 2012-06-13 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Hemostatic effect of a monoclonal antibody mAb 2021 blocking the interaction between FXa and TFPI in a rabbit hemophilia model. Blood, 119, 2012
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4DGC
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![BU of 4dgc by Molmil](/molmil-images/mine/4dgc) | TRIMCyp cyclophilin domain from Macaca mulatta: cyclosporin A complex | 分子名称: | TRIMCyp, cyclosporin A | 著者 | Caines, M.E.C, Bichel, K, Price, A.J, McEwan, W.A, James, L.C. | 登録日 | 2012-01-25 | 公開日 | 2012-02-08 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Diverse HIV viruses are targeted by a conformationally dynamic antiviral. Nat.Struct.Mol.Biol., 19, 2012
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3DR8
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![BU of 3dr8 by Molmil](/molmil-images/mine/3dr8) | Structure of yncA, a putative ACETYLTRANSFERASE from Salmonella typhimurium with its cofactor Acetyl-CoA | 分子名称: | ACETATE ION, ACETYL COENZYME *A, CHLORIDE ION, ... | 著者 | Singer, A.U, Skarina, T, Onopriyenko, O, Edwards, A.M, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2008-07-10 | 公開日 | 2008-08-12 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure of yncA, a putative ACETYLTRANSFERASE from Salmonella typhimurium with its cofactor Acetyl-CoA To be Published
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1D6D
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![BU of 1d6d by Molmil](/molmil-images/mine/1d6d) | SOLUTION DNA STRUCTURE CONTAINING (A-A)-T TRIADS INTERDIGITATED BETWEEN A-T BASE PAIRS AND GGGG TETRADS; NMR, 8 STRUCT. | 分子名称: | 5'-D(*AP*AP*GP*GP*TP*TP*TP*TP*AP*AP*GP*G)-3' | 著者 | Kuryavyi, V.V, Kettani, A, Wang, W, Jones, R, Patel, D.J. | 登録日 | 1999-10-13 | 公開日 | 2000-01-17 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | A diamond-shaped zipper-like DNA architecture containing triads sandwiched between mismatches and tetrads. J.Mol.Biol., 295, 2000
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5QTZ
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![BU of 5qtz by Molmil](/molmil-images/mine/5qtz) | TGF-BETA RECEPTOR TYPE 1 KINASE DOMAIN (T204D) IN COMPLEX WITH 6-[1-(2,2-DIFLUOROETHYL)-4-(6-METHYLPYRIDIN-2-YL)-1H-IMIDAZOL-5-YL]IMIDAZO[1,2-A]PYRIDINE | 分子名称: | 6-[1-(2,2-difluoroethyl)-4-(6-methylpyridin-2-yl)-1H-imidazol-5-yl]imidazo[1,2-a]pyridine, GLYCEROL, TGF-beta receptor type-1 | 著者 | Sheriff, S. | 登録日 | 2019-11-19 | 公開日 | 2020-02-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Discovery of BMS-986260, a Potent, Selective, and Orally Bioavailable TGF beta R1 Inhibitor as an Immuno-oncology Agent. Acs Med.Chem.Lett., 11, 2020
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4EUD
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