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8FND
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BU of 8fnd by Molmil
Structure of E138K HIV-1 intasome with Dolutegravir bound
分子名称: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ...
著者Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D.
登録日2022-12-27
公開日2023-08-09
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants.
Sci Adv, 9, 2023
8FNO
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BU of 8fno by Molmil
Structure of E138K/G140A/Q148R HIV-1 intasome with Dolutegravir bound
分子名称: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ...
著者Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D.
登録日2022-12-28
公開日2023-08-09
最終更新日2023-09-20
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants.
Sci Adv, 9, 2023
8FNG
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BU of 8fng by Molmil
Structure of E138K HIV-1 intasome with Dolutegravir bound
分子名称: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ...
著者Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D.
登録日2022-12-27
公開日2023-08-09
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants.
Sci Adv, 9, 2023
8FNH
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BU of 8fnh by Molmil
Structure of Q148K HIV-1 intasome with Dolutegravir bound
分子名称: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ...
著者Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D.
登録日2022-12-27
公開日2023-08-09
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants.
Sci Adv, 9, 2023
8FNM
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BU of 8fnm by Molmil
Structure of G140A/Q148K HIV-1 intasome with Dolutegravir bound
分子名称: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ...
著者Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D.
登録日2022-12-27
公開日2023-08-09
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants.
Sci Adv, 9, 2023
8FNP
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BU of 8fnp by Molmil
Structure of E138K/G140S/Q148H HIV-1 intasome with Dolutegravir bound
分子名称: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ...
著者Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D.
登録日2022-12-28
公開日2023-08-09
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants.
Sci Adv, 9, 2023
8FNQ
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Structure of E138K/G140A/Q148K HIV-1 intasome with 4d bound
分子名称: 4-amino-N-[(2,4-difluorophenyl)methyl]-1-hydroxy-6-(6-hydroxyhexyl)-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide, DNA (25-MER), DNA (27-MER), ...
著者Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D.
登録日2022-12-28
公開日2023-08-09
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants.
Sci Adv, 9, 2023
8FEG
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BU of 8feg by Molmil
CryoEM structure of Kappa Opioid Receptor bound to a semi-peptide and Gi1
分子名称: ACE-TYR-ALA-DTY-THR-THR-CYS-THR-DPN-XT9, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Fay, J.F, Che, T.
登録日2022-12-06
公開日2023-12-06
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (2.54 Å)
主引用文献Design and structural validation of peptide-drug conjugate ligands of the kappa-opioid receptor.
Nat Commun, 14, 2023
1GBD
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BU of 1gbd by Molmil
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID
分子名称: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID INHIBITOR, SULFATE ION
著者Mace, J.E, Agard, D.A.
登録日1995-09-06
公開日1996-01-29
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
6EST
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BU of 6est by Molmil
INTERACTION OF THE PEPTIDE CF3-LEU-ALA-NH-C6H4-CF3(TFLA) WITH PORCINE PANCREATIC ELASTASE. X-RAY STUDIES AT 1.8 ANGSTROMS
分子名称: CALCIUM ION, DIMETHYLFORMAMIDE, PORCINE PANCREATIC ELASTASE, ...
著者Prange, T, Li De Lasierra, I.
登録日1990-06-15
公開日1991-10-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Interaction of the peptide CF3-Leu-Ala-NH-C6H4-CF3 (TFLA) with porcine pancreatic elastase. X-ray studies at 1.8 A.
J.Mol.Recog., 3, 1990
1GBM
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BU of 1gbm by Molmil
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID
分子名称: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID INHIBITOR, SULFATE ION
著者Mace, J.E, Agard, D.A.
登録日1995-09-06
公開日1996-01-29
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
1GBB
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BU of 1gbb by Molmil
Alpha-lytic protease with met 190 replaced by ALA AND GLY 216 replaced by ALA complex with METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID
分子名称: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID INHIBITOR, SULFATE ION
著者Mace, J.E, Agard, D.A.
登録日1995-09-06
公開日1996-01-29
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
1GBI
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BU of 1gbi by Molmil
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY LEU COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID
分子名称: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID INHIBITOR, SULFATE ION
著者Mace, J.E, Agard, D.A.
登録日1995-09-06
公開日1996-01-29
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
1GBL
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BU of 1gbl by Molmil
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID
分子名称: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID INHIBITOR, SULFATE ION
著者Mace, J.E, Agard, D.A.
登録日1995-09-06
公開日1996-01-29
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
1GBC
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BU of 1gbc by Molmil
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID
分子名称: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID INHIBITOR, SULFATE ION
著者Mace, J.E, Agard, D.A.
登録日1995-09-06
公開日1996-01-29
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
1GBH
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BU of 1gbh by Molmil
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY LEU COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID
分子名称: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID INHIBITOR, SULFATE ION
著者Mace, J.E, Agard, D.A.
登録日1995-09-06
公開日1996-01-29
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
1GBK
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BU of 1gbk by Molmil
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID
分子名称: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID INHIBITOR, SULFATE ION
著者Mace, J.E, Agard, D.A.
登録日1995-09-06
公開日1996-01-29
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
1GBF
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BU of 1gbf by Molmil
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY LEU COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID
分子名称: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID INHIBITOR, SULFATE ION
著者Mace, J.E, Agard, D.A.
登録日1995-09-06
公開日1996-01-29
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
8H05
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BU of 8h05 by Molmil
Minor polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2022-09-28
公開日2022-11-30
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
8H03
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BU of 8h03 by Molmil
Major polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a preclinical Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2022-09-28
公開日2022-11-30
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
8H04
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BU of 8h04 by Molmil
Major polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2022-09-28
公開日2022-11-30
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
8H8C
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BU of 8h8c by Molmil
Type VI secretion system effector RhsP in its post-autoproteolysis and dimeric form
分子名称: C-terminal peptide from Putative Rhs-family protein, Putative Rhs-family protein
著者Tang, L, Dong, S.Q, Rasheed, N, Wu, H.W, Zhou, N.K, Li, H.D, Wang, M.L, Zheng, J, He, J, Chao, W.C.H.
登録日2022-10-22
公開日2023-01-18
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献Vibrio parahaemolyticus prey targeting requires autoproteolysis-triggered dimerization of the type VI secretion system effector RhsP.
Cell Rep, 41, 2022
8H8B
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BU of 8h8b by Molmil
Type VI secretion system effector RhsP in its pre-autoproteolysis and monomeric form
分子名称: Putative Rhs-family protein
著者Tang, L, Dong, S.Q, Rasheed, N, Wu, H.W, Zhou, N.K, Li, H.D, Wang, M.L, Zheng, J, He, J, Chao, W.C.H.
登録日2022-10-22
公開日2023-01-18
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Vibrio parahaemolyticus prey targeting requires autoproteolysis-triggered dimerization of the type VI secretion system effector RhsP.
Cell Rep, 41, 2022
8H8A
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BU of 8h8a by Molmil
Type VI secretion system effector RhsP in its post-autoproteolysis and monomeric form
分子名称: C-terminal peptide from Putative Rhs-family protein, Putative Rhs-family protein
著者Tang, L, Dong, S.Q, Rasheed, N, Wu, H.W, Zhou, N.K, Li, H.D, Wang, M.L, Zheng, J, He, J, Chao, W.C.H.
登録日2022-10-22
公開日2023-01-18
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Vibrio parahaemolyticus prey targeting requires autoproteolysis-triggered dimerization of the type VI secretion system effector RhsP.
Cell Rep, 41, 2022
8WTB
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BU of 8wtb by Molmil
Crystal structure of McsA/McsB complex truncated by chymotrypsin
分子名称: Protein-arginine kinase, Protein-arginine kinase activator protein, ZINC ION
著者Arifuzzaman, M, Kwon, E, Kim, D.Y.
登録日2023-10-18
公開日2024-05-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural insights into the regulation of protein-arginine kinase McsB by McsA.
Proc.Natl.Acad.Sci.USA, 121, 2024

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