Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7WPU
DownloadVisualize
BU of 7wpu by Molmil
The 0.95 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with undecanoic acid
分子名称: Fatty acid-binding protein, heart, PENTAETHYLENE GLYCOL, ...
著者Sugiyama, S, Matsuoka, S, Tsuchikawa, H, Sonoyama, M, Inoue, Y, Hayashi, F, Murata, M.
登録日2022-01-24
公開日2023-01-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献The 0.95 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with undecanoic acid
To Be Published
7WOM
DownloadVisualize
BU of 7wom by Molmil
The 0.90 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with eicosapentaenoic acid
分子名称: 5,8,11,14,17-EICOSAPENTAENOIC ACID, Fatty acid-binding protein, heart
著者Sugiyama, S, Kakinouchi, K, Nakano, R, Matsuoka, S, Tsuchikawa, H, Sonoyama, M, Inoue, Y, Hayashi, F, Murata, M.
登録日2022-01-21
公開日2023-01-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (0.9 Å)
主引用文献The 0.90 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with eicosapentaenoic acid
To Be Published
5QIM
DownloadVisualize
BU of 5qim by Molmil
TGF-BETA RECEPTOR TYPE 1 KINASE DOMAIN (T204D) IN COMPLEX WITH N-{4-[3-(5-METHOXYPYRIDIN-2-YL)-1H-PYRROLO[3,2-B] PYRIDIN-2-YL]PYRIDIN-2-YL}ACETAMIDE
分子名称: GLYCEROL, N-{4-[3-(5-methoxypyridin-2-yl)-1H-pyrrolo[3,2-b]pyridin-2-yl]pyridin-2-yl}acetamide, TGF-beta receptor type-1
著者Sheriff, S.
登録日2018-08-05
公開日2018-10-31
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Discovery of 4-Azaindole Inhibitors of TGF beta RI as Immuno-oncology Agents.
ACS Med Chem Lett, 9, 2018
7WKG
DownloadVisualize
BU of 7wkg by Molmil
The 0.84 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with erucic acid
分子名称: (Z)-docos-13-enoic acid, Fatty acid-binding protein, heart, ...
著者Sugiyama, S, Kakinouchi, K, Nakano, R, Matsuoka, S, Tsuchikawa, H, Sonoyama, M, Inoue, Y, Hayashi, F, Murata, M.
登録日2022-01-09
公開日2023-01-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (0.84 Å)
主引用文献The 0.84 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with erucic acid
To Be Published
7WPG
DownloadVisualize
BU of 7wpg by Molmil
The 0.90 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with heptanoic acid
分子名称: Fatty acid-binding protein, heart, HEXAETHYLENE GLYCOL, ...
著者Sugiyama, S, Matsuoka, S, Tsuchikawa, H, Sonoyama, M, Inoue, Y, Hayashi, F, Murata, M.
登録日2022-01-23
公開日2023-01-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (0.9 Å)
主引用文献The 0.90 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with heptanoic acid
To Be Published
3SKF
DownloadVisualize
BU of 3skf by Molmil
Crystal structure of beta-site app-cleaving enzyme 1 (BACE-WT) complex with (2S)-2-((3S)-3-(acetylamino)-3-(butan-2-yl)-2-oxopyrrolidin-1-yl)-N-((2S,3R)-3-hydroxy-4-((3-methoxybenzyl)amino)-1-phenylbutan-2-yl)-4-phenylbutanamide
分子名称: (2S)-2-{(3S)-3-(acetylamino)-3-[(2S)-butan-2-yl]-2-oxopyrrolidin-1-yl}-N-{(2S,3R)-3-hydroxy-4-[(3-methoxybenzyl)amino]-1-phenylbutan-2-yl}-4-phenylbutanamide, Beta-secretase 1, IODIDE ION
著者Muckelbauer, J.K.
登録日2011-06-22
公開日2011-08-31
最終更新日2011-11-02
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Synthesis and in vivo evaluation of cyclic diaminopropane BACE-1 inhibitors.
Bioorg.Med.Chem.Lett., 21, 2011
3SLZ
DownloadVisualize
BU of 3slz by Molmil
The crystal structure of XMRV protease complexed with TL-3
分子名称: FORMIC ACID, SODIUM ION, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate, ...
著者Li, M, Gustchina, A, Wlodawer, A.
登録日2011-06-27
公開日2011-10-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural and biochemical characterization of the inhibitor complexes of xenotropic murine leukemia virus-related virus protease.
Febs J., 278, 2011
3SM2
DownloadVisualize
BU of 3sm2 by Molmil
The crystal structure of XMRV protease complexed with Amprenavir
分子名称: gag-pro-pol polyprotein, {3-[(4-AMINO-BENZENESULFONYL)-ISOBUTYL-AMINO]-1-BENZYL-2-HYDROXY-PROPYL}-CARBAMIC ACID TETRAHYDRO-FURAN-3-YL ESTER
著者Li, M, Gustchina, A, Wlodawer, A.
登録日2011-06-27
公開日2011-10-12
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural and biochemical characterization of the inhibitor complexes of xenotropic murine leukemia virus-related virus protease.
Febs J., 278, 2011
3SOD
DownloadVisualize
BU of 3sod by Molmil
CHANGES IN CRYSTALLOGRAPHIC STRUCTURE AND THERMOSTABILITY OF A CU,ZN SUPEROXIDE DISMUTASE MUTANT RESULTING FROM THE REMOVAL OF BURIED CYSTEINE
分子名称: COPPER (II) ION, COPPER,ZINC SUPEROXIDE DISMUTASE, ZINC ION
著者Mcree, D.E, Redford, S.M, Getzoff, E.D, Lepock, J.R, Hallewell, R.A, Tainer, J.A.
登録日1990-06-26
公開日1993-04-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Changes in crystallographic structure and thermostability of a Cu,Zn superoxide dismutase mutant resulting from the removal of a buried cysteine.
J.Biol.Chem., 265, 1990
3SGA
DownloadVisualize
BU of 3sga by Molmil
STRUCTURES OF PRODUCT AND INHIBITOR COMPLEXES OF STREPTOMYCES GRISEUS PROTEASE A AT 1.8 ANGSTROMS RESOLUTION. A MODEL FOR SERINE PROTEASE CATALYSIS
分子名称: ACE-PRO-ALA-PRO-PHE-ALDEHYDE, PROTEINASE A (SGPA)
著者Sielecki, A.R, James, M.N.G.
登録日1990-05-29
公開日1991-10-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of product and inhibitor complexes of Streptomyces griseus protease A at 1.8 A resolution. A model for serine protease catalysis.
J.Mol.Biol., 144, 1980
3SOS
DownloadVisualize
BU of 3sos by Molmil
Benzothiazinone inhibitor in complex with FXIa
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CITRIC ACID, Coagulation factor XI, ...
著者Fradera, X, Kazemier, B, Oubrie, A.
登録日2011-06-30
公開日2012-04-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献High-resolution crystal structures of factor XIa coagulation factor in complex with nonbasic high-affinity synthetic inhibitors.
Acta Crystallogr.,Sect.F, 68, 2012
5NHH
DownloadVisualize
BU of 5nhh by Molmil
Human Erk2 with an Erk1/2 inhibitor
分子名称: 5-(2-methoxyethyl)-2-[2-(oxan-4-ylamino)pyrimidin-4-yl]-6,7-dihydro-1~{H}-pyrrolo[3,2-c]pyridin-4-one, Mitogen-activated protein kinase 1, SULFATE ION
著者Debreczeni, J.E, Ward, R.A, Bethel, P, Cook, C, Davies, E, Eckersley, K, Fairley, G, Feron, L, Flemington, V, Graham, M.A, Greenwood, R, Hopcroft, P, Howard, T.D, Hudson, J, James, M, Jones, C.D, Jones, C.R, Lamont, S, Lewis, R, Lindsay, N, Roberts, K, Simpson, I, StGallay, S, Swallow, S, Tonge, M.
登録日2017-03-21
公開日2017-04-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structure-Guided Discovery of Potent and Selective Inhibitors of ERK1/2 from a Modestly Active and Promiscuous Chemical Start Point.
J. Med. Chem., 60, 2017
5NHO
DownloadVisualize
BU of 5nho by Molmil
Human Erk2 with an Erk1/2 inhibitor
分子名称: (6~{S})-5-(2-methoxyethyl)-6-methyl-2-[5-methyl-2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-6,7-dihydro-1~{H}-pyrrolo[3,2-c]pyridin-4-one, Mitogen-activated protein kinase 1, SULFATE ION
著者Debreczeni, J.E, Ward, R.A, Bethel, P, Cook, C, Davies, E, Eckersley, K, Fairley, G, Feron, L, Flemington, V, Graham, M.A, Greenwood, R, Hopcroft, P, Howard, T.D, Hudson, J, James, M, Jones, C.D, Jones, C.R, Lamont, S, Lewis, R, Lindsay, N, Roberts, K, Simpson, I, StGallay, S, Swallow, S, Tonge, M.
登録日2017-03-22
公開日2017-04-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Structure-Guided Discovery of Potent and Selective Inhibitors of ERK1/2 from a Modestly Active and Promiscuous Chemical Start Point.
J. Med. Chem., 60, 2017
5NHV
DownloadVisualize
BU of 5nhv by Molmil
Human Erk2 with an Erk1/2 inhibitor
分子名称: 7-[2-(oxan-4-ylamino)pyrimidin-4-yl]-3,4-dihydro-2~{H}-pyrrolo[1,2-a]pyrazin-1-one, Mitogen-activated protein kinase 1, SULFATE ION
著者Debreczeni, J.E, Ward, R.A, Bethel, P, Cook, C, Davies, E, Eckersley, K, Fairley, G, Feron, L, Flemington, V, Graham, M.A, Greenwood, R, Hopcroft, P, Howard, T.D, Hudson, J, James, M, Jones, C.D, Jones, C.R, Lamont, S, Lewis, R, Lindsay, N, Roberts, K, Simpson, I, StGallay, S, Swallow, S, Tonge, M.
登録日2017-03-22
公開日2017-04-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure-Guided Discovery of Potent and Selective Inhibitors of ERK1/2 from a Modestly Active and Promiscuous Chemical Start Point.
J. Med. Chem., 60, 2017
7XGY
DownloadVisualize
BU of 7xgy by Molmil
cryo-EM structure of hemoglobin
分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE
著者Liu, N, Wang, H.W.
登録日2022-04-07
公開日2022-11-09
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Uniform thin ice on ultraflat graphene for high-resolution cryo-EM.
Nat.Methods, 20, 2023
3T1T
DownloadVisualize
BU of 3t1t by Molmil
MglA bound to GDP in P1 tetrameric arrangement
分子名称: GUANOSINE-5'-DIPHOSPHATE, Gliding protein mglA
著者Miertzschke, M, Vetter, I.R, Koerner, C, Wittinghofer, A.
登録日2011-07-22
公開日2011-08-31
最終更新日2011-11-02
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural analysis of the Ras-like G protein MglA and its cognate GAP MglB and implications for bacterial polarity.
Embo J., 30, 2011
3T28
DownloadVisualize
BU of 3t28 by Molmil
TMAO-grown trypsin (bovine)-previously unreported tetragonal crystal form
分子名称: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ...
著者Cahn, J, Venkat, M, Saxby, S, Juers, D.
登録日2011-07-22
公開日2011-12-28
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography.
Acta Crystallogr.,Sect.D, 68, 2012
3T3S
DownloadVisualize
BU of 3t3s by Molmil
Human Cytochrome P450 2A13 in complex with Pilocarpine
分子名称: (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one, Cytochrome P450 2A13, PROTOPORPHYRIN IX CONTAINING FE
著者DeVore, N.M, Scott, E.E.
登録日2011-07-25
公開日2011-12-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural comparison of cytochromes P450 2A6, 2A13, and 2E1 with pilocarpine.
Febs J., 279, 2012
5NGU
DownloadVisualize
BU of 5ngu by Molmil
Human Erk2 with an Erk1/2 inhibitor
分子名称: 2-[2-[[4-(4-methylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one, Mitogen-activated protein kinase 1, SULFATE ION
著者Debreczeni, J.E, Ward, R.A, Bethel, P, Cook, C, Davies, E, Eckersley, K, Fairley, G, Feron, L, Flemington, V, Graham, M.A, Greenwood, R, Hopcroft, P, Howard, T.D, Hudson, J, James, M, Jones, C.D, Jones, C.R, Lamont, S, Lewis, R, Lindsay, N, Roberts, K, Simpson, I, StGallay, S, Swallow, S, Tonge, M.
登録日2017-03-20
公開日2017-04-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Structure-Guided Discovery of Potent and Selective Inhibitors of ERK1/2 from a Modestly Active and Promiscuous Chemical Start Point.
J. Med. Chem., 60, 2017
7Y9O
DownloadVisualize
BU of 7y9o by Molmil
Crystal structure of a CYP109B4 variant from Bacillus sonorensis
分子名称: CALCIUM ION, Cytochrome P450 monooxygenase YjiB, IMIDAZOLE, ...
著者Shen, P.P, Huang, J.-W, Li, X, Liu, W.D, Chen, C.-C, Guo, R.-T.
登録日2022-06-25
公開日2023-05-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Rationally Controlling Selective Steroid Hydroxylation via Scaffold Sampling of a P450 Family
Acs Catalysis, 13, 2023
7XR8
DownloadVisualize
BU of 7xr8 by Molmil
Structure of the S8 family protease A4095
分子名称: Major intracellular serine protease
著者Cheng, J.H, Cao, H.Y, Wang, P.
登録日2022-05-09
公開日2023-05-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structure of the S8 family protease A4095
To Be Published
7Y97
DownloadVisualize
BU of 7y97 by Molmil
Crystal structure of CYP109B4 from Bacillus Sonorensis
分子名称: Cytochrome P450 monooxygenase YjiB, PROTOPORPHYRIN IX CONTAINING FE
著者Shen, P.P, Huang, J.-W, Li, X, Liu, W.D, Chen, C.-C, Guo, R.-T.
登録日2022-06-24
公開日2023-05-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Rationally Controlling Selective Steroid Hydroxylation via Scaffold Sampling of a P450 Family
Acs Catalysis, 13, 2023
7XVV
DownloadVisualize
BU of 7xvv by Molmil
Structure of neuraminidase from influenza B-like viruses derived from spiny eel
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neuraminidase, ...
著者Chai, Y, Gao, F.
登録日2022-05-24
公開日2023-05-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural and inhibitor sensitivity analysis of influenza B-like viral neuraminidases derived from Asiatic toad and spiny eel.
Proc.Natl.Acad.Sci.USA, 119, 2022
7XVW
DownloadVisualize
BU of 7xvw by Molmil
Structure of neuraminidase from influenza B-like viruses derived from spiny eel
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(1-ACETYLAMINO-2-ETHYL-BUTYL)-4-GUANIDINO-2-HYDROXY-CYCLOPENTANECARBOXYLIC ACID, CALCIUM ION, ...
著者Chai, Y, Gao, F.
登録日2022-05-25
公開日2023-05-31
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural and inhibitor sensitivity analysis of influenza B-like viral neuraminidases derived from Asiatic toad and spiny eel.
Proc.Natl.Acad.Sci.USA, 119, 2022
7Y98
DownloadVisualize
BU of 7y98 by Molmil
Crystal structure of CYP109B4 from Bacillus Sonorensis in complex with Testosterone
分子名称: Cytochrome P450 monooxygenase YjiB, PROTOPORPHYRIN IX CONTAINING FE, TESTOSTERONE
著者Shen, P.P, Huang, J.-W, Li, X, Liu, W.D, Chen, C.-C, Guo, R.-T.
登録日2022-06-24
公開日2023-05-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Rationally Controlling Selective Steroid Hydroxylation via Scaffold Sampling of a P450 Family
Acs Catalysis, 13, 2023

226262

件を2024-10-16に公開中

PDB statisticsPDBj update infoContact PDBjnumon