1FNM
| STRUCTURE OF THERMUS THERMOPHILUS EF-G H573A | 分子名称: | ELONGATION FACTOR G, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | 著者 | Laurberg, M, Kristensen, O, Martemyanov, K, Gudkov, A.T, Nagaev, I, Hughes, D, Liljas, A. | 登録日 | 2000-08-22 | 公開日 | 2000-11-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of a mutant EF-G reveals domain III and possibly the fusidic acid binding site. J.Mol.Biol., 303, 2000
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3ZMB
| Native structure of Farnesyl Pyrophosphate Synthase from Pseudomonas aeruginosa PA01, with bound fragment SPB02696. | 分子名称: | 3-(2-oxo-1,3-benzoxazol-3(2H)-yl)propanoic acid, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Schmidberger, J.W, Schnell, R, Schneider, G. | 登録日 | 2013-02-07 | 公開日 | 2014-02-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Characterization of Substrate and Inhibitor Binding to Farnesyl Pyrophosphate Synthase from Pseudomonas Aeruginosa Acta Crystallogr.,Sect.D, 71, 2015
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3ZL6
| Native structure of Farnesyl Pyrophosphate Synthase from Pseudomonas aeruginosa PAO1, with bound fragment KM10833. | 分子名称: | 2-(1,2-benzoxazol-3-yl)ethanoic acid, DIMETHYL SULFOXIDE, GERANYLTRANSTRANSFERASE, ... | 著者 | Schmidberger, J.W, Schnell, R, Schneider, G. | 登録日 | 2013-01-28 | 公開日 | 2014-02-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural Characterization of Substrate and Inhibitor Binding to Farnesyl Pyrophosphate Synthase from Pseudomonas Aeruginosa. Acta Crystallogr.,Sect.D, 71, 2015
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1SOQ
| Crystal structure of the transthyretin mutant A108Y/L110E solved in space group C2 | 分子名称: | Transthyretin | 著者 | Hornberg, A, Olofsson, A, Eneqvist, T, Lundgren, E, Sauer-Eriksson, A.E. | 登録日 | 2004-03-15 | 公開日 | 2004-07-06 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The beta-strand D of transthyretin trapped in two discrete conformations Biochim.Biophys.Acta, 1700, 2004
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423D
| 5'-D(*AP*CP*CP*GP*AP*CP*GP*TP*CP*GP*GP*T)-3' | 分子名称: | DNA (5'-D(*AP*CP*CP*GP*AP*CP*GP*TP*CP*GP*GP*T)-3'), MAGNESIUM ION | 著者 | Rozenberg, H, Rabinovich, D, Frolow, F, Hegde, R.S, Shakked, Z. | 登録日 | 1998-09-14 | 公開日 | 1999-10-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural code for DNA recognition revealed in crystal structures of papillomavirus E2-DNA targets. Proc.Natl.Acad.Sci.USA, 95, 1998
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4A82
| Fitted model of staphylococcus aureus sav1866 model ABC transporter in the human cystic fibrosis transmembrane conductance regulator volume map EMD-1966. | 分子名称: | CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | 著者 | Rosenberg, M.F, ORyan, L.P, Hughes, G, Zhao, Z, Aleksandrov, L.A, Riordan, J.R, Ford, R.C. | 登録日 | 2011-11-18 | 公開日 | 2012-01-11 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (9 Å) | 主引用文献 | The Cystic Fibrosis Transmembrane Conductance Regulator (Cftr):3D Structure and Localisation of a Channel Gate. J.Biol.Chem., 286, 2011
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6RSJ
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3ZXU
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1RRC
| T4 POLYNUCLEOTIDE KINASE BOUND TO 5'-GTC-3' SSDNA | 分子名称: | 5'-D(*GP*TP*C)-3', ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | 著者 | Eastberg, J.H, Pelletier, J, Stoddard, B.L. | 登録日 | 2003-12-08 | 公開日 | 2004-02-17 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | Recognition of DNA substrates by T4 bacteriophage polynucleotide kinase. Nucleic Acids Res., 32, 2004
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424D
| 5'-D(*AP*CP*CP*GP*AP*CP*GP*TP*CP*GP*GP*T)-3' | 分子名称: | DNA (5'-D(*AP*CP*CP*GP*AP*CP*GP*TP*CP*GP*GP*T)-3') | 著者 | Rozenberg, H, Rabinovich, D, Frolow, F, Hegde, R.S, Shakked, Z. | 登録日 | 1998-09-14 | 公開日 | 1999-10-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural code for DNA recognition revealed in crystal structures of papillomavirus E2-DNA targets. Proc.Natl.Acad.Sci.USA, 95, 1998
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425D
| 5'-D(*AP*CP*CP*GP*GP*TP*AP*CP*CP*GP*GP*T)-3' | 分子名称: | DNA (5'-D(*AP*CP*CP*GP*GP*TP*AP*CP*CP*GP*GP*T)-3') | 著者 | Rozenberg, H, Rabinovich, D, Frolow, F, Hegde, R.S, Shakked, Z. | 登録日 | 1998-09-14 | 公開日 | 1999-10-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural code for DNA recognition revealed in crystal structures of papillomavirus E2-DNA targets. Proc.Natl.Acad.Sci.USA, 95, 1998
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4AOF
| Selective small molecule inhibitor discovered by chemoproteomic assay platform reveals regulation of Th17 cell differentiation by PI3Kgamma | 分子名称: | N-[6-(5-methylsulfonylpyridin-3-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]ethanamide, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM | 著者 | Bergamini, G, Bell, K, Shimamura, S, Werner, T, Cansfield, A, Muller, K, Perrin, J, Rau, C, Ellard, K, Hopf, C, Doce, C, Leggate, D, Mangano, R, Mathieson, T, OMahony, A, Plavec, I, Rharbaoui, F, Reinhard, F, Savitski, M.M, Ramsden, N, Hirsch, E, Drewes, G, Rausch, O, Bantscheff, M, Neubauer, G. | 登録日 | 2012-03-26 | 公開日 | 2012-05-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | A Selective Inhibitor Reveals Pi3Kgamma Dependence of T(H)17 Cell Differentiation. Nat.Chem.Biol., 8, 2012
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4AGW
| Discovery of a small molecule type II inhibitor of wild-type and gatekeeper mutants of BCR-ABL, PDGFRalpha, Kit, and Src kinases | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-{2-[(cyclopropylcarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}-N-{4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromet hyl)phenyl}benzamide, GLYCEROL, ... | 著者 | Weisberg, E, Choi, H.G, Seeliger, M, Gray, N, Griffin, J.D. | 登録日 | 2012-02-01 | 公開日 | 2012-02-15 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Discovery of a Small-Molecule Type II Inhibitor of Wild-Type and Gatekeeper Mutants of Bcr-Abl, Pdgfralpha, Kit, and Src Kinases: Novel Type II Inhibitor of Gatekeeper Mutants. Blood, 115, 2010
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1UV0
| Pancreatitis-associated protein 1 from human | 分子名称: | PANCREATITIS-ASSOCIATED PROTEIN 1, ZINC ION | 著者 | Abergel, C, Shepard, W, Christal, L. | 登録日 | 2004-01-12 | 公開日 | 2004-01-14 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Crystallization and preliminary crystallographic study of HIP/PAP, a human C-lectin overexpressed in primary liver cancers. Acta Crystallogr.,Sect.D, 55, 1999
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1GHJ
| SOLUTION STRUCTURE OF THE LIPOYL DOMAIN OF THE 2-OXOGLUTARATE DEHYDROGENASE COMPLEX FROM AZOTOBACTER VINELAND II, NMR, MINIMIZED AVERAGE STRUCTURE | 分子名称: | E2, THE DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX | 著者 | Berg, A, Vervoort, J, De Kok, A. | 登録日 | 1996-01-16 | 公開日 | 1997-01-11 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the lipoyl domain of the 2-oxoglutarate dehydrogenase complex from Azotobacter vinelandii. J.Mol.Biol., 261, 1996
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1SOK
| Crystal structure of the transthyretin mutant A108Y/L110E solved in space group p21212 | 分子名称: | Transthyretin | 著者 | Hornberg, A, Olofsson, A, Eneqvist, T, Lundgren, E, Sauer-Eriksson, A.E. | 登録日 | 2004-03-15 | 公開日 | 2004-07-06 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The beta-strand D of transthyretin trapped in two discrete conformations Biochim.Biophys.Acta, 1700, 2004
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1GHK
| SOLUTION STRUCTURE OF THE LIPOYL DOMAIN OF THE 2-OXOGLUTARATE DEHYDROGENASE COMPLEX FROM AZOTOBACTER VINELAND II, NMR, 25 STRUCTURES | 分子名称: | E2, THE DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX | 著者 | Berg, A, Vervoort, J, De Kok, A. | 登録日 | 1996-01-16 | 公開日 | 1997-01-11 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the lipoyl domain of the 2-oxoglutarate dehydrogenase complex from Azotobacter vinelandii. J.Mol.Biol., 261, 1996
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1UUZ
| IVY:A NEW FAMILY OF PROTEIN | 分子名称: | INHIBITOR OF VERTEBRATE LYSOZYME, LYSOZYME C | 著者 | Abergel, C, Lembo, F, Byrne, D, Maza, C, Claverie, J.M. | 登録日 | 2004-01-12 | 公開日 | 2004-01-14 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure and Evolution of the Ivy Protein Family, Unexpected Lysozyme Inhibitors in Gram-Negative Bacteria. Proc.Natl.Acad.Sci.USA, 104, 2007
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1T4E
| Structure of Human MDM2 in complex with a Benzodiazepine Inhibitor | 分子名称: | (4-CHLOROPHENYL)[3-(4-CHLOROPHENYL)-7-IODO-2,5-DIOXO-1,2,3,5-TETRAHYDRO-4H-1,4-BENZODIAZEPIN-4-YL]ACETIC ACID, Ubiquitin-protein ligase E3 Mdm2 | 著者 | Grasberger, B.L, Schubert, C, Koblish, H.K, Carver, T.E, Franks, C.F, Zhao, S.Y, Lu, T, LaFrance, L.V, Parks, D.J. | 登録日 | 2004-04-29 | 公開日 | 2005-02-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells J.Med.Chem., 48, 2005
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1W4H
| Peripheral-subunit from mesophilic, thermophilic and hyperthermophilic bacteria fold by ultrafast, apparently two-state transitions | 分子名称: | DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE | 著者 | Ferguson, N, Sharpe, T.D, Schartau, P.J, Allen, M.D, Johnson, C.M, Fersht, A.R. | 登録日 | 2004-07-23 | 公開日 | 2005-07-20 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Ultra-Fast Barrier-Limited Folding in the Peripheral Subunit-Binding Domain Family. J.Mol.Biol., 353, 2005
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1DIK
| PYRUVATE PHOSPHATE DIKINASE | 分子名称: | PYRUVATE PHOSPHATE DIKINASE, SULFATE ION | 著者 | Herzberg, O, Chen, C.C.H. | 登録日 | 1995-12-06 | 公開日 | 1996-04-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Swiveling-domain mechanism for enzymatic phosphotransfer between remote reaction sites. Proc.Natl.Acad.Sci.USA, 93, 1996
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1EGI
| STRUCTURE OF A C-TYPE CARBOHYDRATE-RECOGNITION DOMAIN (CRD-4) FROM THE MACROPHAGE MANNOSE RECEPTOR | 分子名称: | CALCIUM ION, MACROPHAGE MANNOSE RECEPTOR | 著者 | Feinberg, H, Park-Snyder, S, Kolatkar, A.R, Heise, C.T, Taylor, M.E, Weis, W.I. | 登録日 | 2000-02-15 | 公開日 | 2000-08-30 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of a C-type carbohydrate recognition domain from the macrophage mannose receptor. J.Biol.Chem., 275, 2000
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3LQV
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3LCC
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3LRU
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