8JB8
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3SQC
| SQUALENE-HOPENE CYCLASE | 分子名称: | SQUALENE--HOPENE CYCLASE | 著者 | Wendt, K.U, Schulz, G.E. | 登録日 | 1998-09-04 | 公開日 | 1999-05-18 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The structure of the membrane protein squalene-hopene cyclase at 2.0 A resolution. J.Mol.Biol., 286, 1999
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6ZG7
| bovine ATP synthase rotor domain, state 1 | 分子名称: | ATP synthase F(0) complex subunit C2, mitochondrial, ATP synthase subunit delta, ... | 著者 | Spikes, T, Montgomery, M.G, Walker, J.E. | 登録日 | 2020-06-18 | 公開日 | 2020-09-09 | 最終更新日 | 2020-09-30 | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | 主引用文献 | Structure of the dimeric ATP synthase from bovine mitochondria. Proc.Natl.Acad.Sci.USA, 117, 2020
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2J10
| p53 tetramerization domain mutant T329F Q331K | 分子名称: | CELLULAR TUMOR ANTIGEN P53 | 著者 | Carbajo, R.J, Mora, P, Sanchez del Pino, M.M, Perez-Paya, E, Pineda-Lucena, A. | 登録日 | 2006-08-08 | 公開日 | 2007-08-28 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solvent-exposed residues located in the beta-sheet modulate the stability of the tetramerization domain of p53--a structural and combinatorial approach. Proteins, 71, 2008
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8TID
| Combined linker domain of N-DRC and associated proteins Tetrahymena | 分子名称: | AAA family ATPase CDC48 subfamily protein, CFAP20, Calmodulin 7-2, ... | 著者 | Ghanaeian, A.G, Majhi, S.M, McCaffrey, C.M, Nami, B.N, Black, C.B, Yang, S.K, Legal, T.L, Papoulas, O.P, Janowska, M.J, Valente-Paterno, M.V, Marcotte, E.M, Wloga, D.W, Bui, K.H. | 登録日 | 2023-07-19 | 公開日 | 2023-09-27 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Integrated modeling of the Nexin-dynein regulatory complex reveals its regulatory mechanism. Nat Commun, 14, 2023
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6Z37
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6ZBB
| bovine ATP synthase Fo domain | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ATP synthase F(0) complex subunit B1, mitochondrial, ... | 著者 | Spikes, T, Montgomery, M.G, Walker, J.E. | 登録日 | 2020-06-08 | 公開日 | 2020-09-09 | 最終更新日 | 2020-09-30 | 実験手法 | ELECTRON MICROSCOPY (3.61 Å) | 主引用文献 | Structure of the dimeric ATP synthase from bovine mitochondria. Proc.Natl.Acad.Sci.USA, 117, 2020
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6ZIU
| bovine ATP synthase stator domain, state 3 | 分子名称: | ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase protein 8, ... | 著者 | Spikes, T.E, Montgomery, M.G, Walker, J.E. | 登録日 | 2020-06-26 | 公開日 | 2020-09-09 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (6.02 Å) | 主引用文献 | Structure of the dimeric ATP synthase from bovine mitochondria. Proc.Natl.Acad.Sci.USA, 117, 2020
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6YYE
| TREM2 extracellular domain (19-131) in complex with single-chain variable fragment (scFv-2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, TREM2 Single chain variable 2, Triggering receptor expressed on myeloid cells 2 | 著者 | Szykowska, A, Preger, C, Krojer, T, Mukhopadhyay, S.M.M, McKinley, G, Graslund, S, Wigren, E, Persson, H, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Di Daniel, E, Burgess-Brown, N, Bullock, A. | 登録日 | 2020-05-04 | 公開日 | 2021-02-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.36 Å) | 主引用文献 | Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain. Structure, 29, 2021
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6OEL
| Engineered Fab bound to IL-4 receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit gamma, Interleukin-4 receptor subunit alpha, ... | 著者 | Jude, K.M, Moraga, I, Spangler, J.B, Garcia, K.C. | 登録日 | 2019-03-27 | 公開日 | 2019-08-07 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | A strategy for the selection of monovalent antibodies that span protein dimer interfaces. J.Biol.Chem., 294, 2019
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4H3G
| Structure of BACE Bound to 2-((7aR)-7a-(4-(3-cyanophenyl)thiophen-2-yl)-2-imino-3-methyl-4-oxohexahydro-1H-pyrrolo[3,4-d]pyrimidin-6(2H)-yl)nicotinonitrile | 分子名称: | 2-{(2E,4aR,7aR)-7a-[4-(3-cyanophenyl)thiophen-2-yl]-2-imino-3-methyl-4-oxooctahydro-6H-pyrrolo[3,4-d]pyrimidin-6-yl}pyridine-3-carbonitrile, Beta-secretase 1, L(+)-TARTARIC ACID | 著者 | Strickland, C, Mandal, M. | 登録日 | 2012-09-13 | 公開日 | 2012-11-07 | 最終更新日 | 2012-11-21 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Design and Validation of Bicyclic Iminopyrimidinones As Beta Amyloid Cleaving Enzyme-1 (BACE1) Inhibitors: Conformational Constraint to Favor a Bioactive Conformation. J.Med.Chem., 55, 2012
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6Z79
| Variant Surface Glycoprotein VSGsur, I3C ("Magic Triangle") derivative used for phasing of the structure and subsequently as a model for molecular replacement of native, mutants, and drug soaks. | 分子名称: | 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, Variant surface glycoprotein Sur, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Zeelen, J.P, Straaten van, M, Stebbins, C.E. | 登録日 | 2020-05-30 | 公開日 | 2021-03-17 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Structure of trypanosome coat protein VSGsur and function in suramin resistance. Nat Microbiol, 6, 2021
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2J0Z
| p53 tetramerization domain wild type | 分子名称: | CELLULAR TUMOR ANTIGEN P53 | 著者 | Carbajo, R.J, Mora, P, Sanchez del Pino, M.M, Perez-Paya, E, Pineda-Lucena, A. | 登録日 | 2006-08-08 | 公開日 | 2007-08-28 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solvent-exposed residues located in the beta-sheet modulate the stability of the tetramerization domain of p53--a structural and combinatorial approach. Proteins, 71, 2008
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6Z8H
| Crystal structure of Variant Surface Glycoprotein VSG13 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Variant surface glycoprotein MITat 1.13, ... | 著者 | Stebbins, C.E, Hempelmann, A, Van Straaten, M, Zeelen, J. | 登録日 | 2020-06-02 | 公開日 | 2021-03-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Structure of trypanosome coat protein VSGsur and function in suramin resistance. Nat Microbiol, 6, 2021
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7U51
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6Z8G
| Crystal structure of VSG13 soaked in 0.5 M used to phase VSG13 to solve the structure. | 分子名称: | BROMIDE ION, SULFATE ION, Variant surface glycoprotein MITat 1.13, ... | 著者 | Stebbins, C.E, Hempelmann, A, Van Straaten, M, Zeelen, J. | 登録日 | 2020-06-02 | 公開日 | 2021-03-17 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Structure of trypanosome coat protein VSGsur and function in suramin resistance. Nat Microbiol, 6, 2021
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7U52
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4HA5
| Structure of BACE Bound to (S)-3-(5-(2-imino-1,4-dimethyl-6-oxohexahydropyrimidin-4-yl)thiophen-3-yl)benzonitrile | 分子名称: | 3-{5-[(2E,4S)-2-imino-1,4-dimethyl-6-oxohexahydropyrimidin-4-yl]thiophen-3-yl}benzonitrile, Beta-secretase 1, L(+)-TARTARIC ACID | 著者 | Strickland, C, Mandal, M. | 登録日 | 2012-09-25 | 公開日 | 2012-10-17 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Design and Validation of Bicyclic Iminopyrimidinones As Beta Amyloid Cleaving Enzyme-1 (BACE1) Inhibitors: Conformational Constraint to Favor a Bioactive Conformation. J.Med.Chem., 55, 2012
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7U50
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6ZDU
| Structure of telomerase from Candida albicans in complexe with TWJ fragment of telomeric RNA | 分子名称: | Chains: C,D, Telomerase reverse transcriptase | 著者 | Zhai, L, Rety, S, Chen, W.F, Auguin, D, Xi, X.G. | 登録日 | 2020-06-15 | 公開日 | 2021-04-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | 主引用文献 | Crystal structures of N-terminally truncated telomerase reverse transcriptase from fungi‡. Nucleic Acids Res., 49, 2021
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6Z4R
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6ZCC
| X-ray structure of the Haloalkane dehalogenase HOB (HaloTag7-based Oligonucleotide Binder) labeled with a chloroalkane-tetramethylrhodamine fluorophore substrate | 分子名称: | ACETATE ION, CALCIUM ION, Haloalkane dehalogenase, ... | 著者 | Tarnawski, M, Johnsson, K, Hiblot, J. | 登録日 | 2020-06-10 | 公開日 | 2021-04-21 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Kinetic and Structural Characterization of the Self-Labeling Protein Tags HaloTag7, SNAP-tag, and CLIP-tag. Biochemistry, 60, 2021
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6Z4T
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6ZD2
| Structure of apo telomerase from Candida Tropicalis truncated from C-terminal domain | 分子名称: | SODIUM ION, Telomerase reverse transcriptase | 著者 | Zhai, L, Rety, S, Chen, W.F, Auguin, D, Xi, X.G. | 登録日 | 2020-06-13 | 公開日 | 2021-04-28 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | 主引用文献 | Crystal structures of N-terminally truncated telomerase reverse transcriptase from fungi‡. Nucleic Acids Res., 49, 2021
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6ZDQ
| Structure of telomerase from Candida albicans in complexe with TWJ fragment of telomeric RNA | 分子名称: | RNA, Telomerase reverse transcriptase | 著者 | Zhai, L, Rety, S, Chen, W.F, Auguin, D, Xi, X.G. | 登録日 | 2020-06-15 | 公開日 | 2021-04-28 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | 主引用文献 | Crystal structures of N-terminally truncated telomerase reverse transcriptase from fungi‡. Nucleic Acids Res., 49, 2021
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